Newsweek

One Day There Could Be a Blood Test for Autism

Tests for the risk of a child being born with the condition are elusive and controversial.
With his service dog, Clyde, by his side, Zachary Tucker, 11, who has Aspergers syndrome (a high functioning form of autism) brushes his teeth in Colorado Springs, Colo. on January 08, 2014.
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More than a decade ago, Judy Van de Water, a neuroimmunologist, decided to follow her instincts and research a condition she knew nothing about. Van de Water, now a lead scientist at the University of California Davis MIND Institute—an international research center for neurodevelopmental disorders—had spent her career studying the immune system. In 2000, she stumbled upon a compelling area of research: the immunobiology of autism.

Through studies on mice, rats and rhesus macaques and, eventually, retrospective and prospective analyses of children diagnosed with autism and their mothers, Van de Water identified eight autoantibodies made by a mother's immune system that appeared to be linked with autism risk if they crossed the placenta. Van de Water, who is also a researcher in the department of internal medicine at UC Davis, refers to her discovery as maternal autoantibody-related autism, or MAR autism. The concept is

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