Bloomberg Businessweek

Growing New Knees

Biotech company Vericel uses a patient’s own cartilage cells to make more

At first, Courtney Mannino blamed the dull ache in her left knee on a ligament she’d torn in high school. She ignored it as long as she could, but she had to cut her 4-mile runs in half, then to zero when the pain wouldn’t let up. Soon the young doctor cringed at the thought of even navigating some stairs to get to work. The diagnosis was unlucky: cartilage damage too severe to be treated with cortisone shots and over-the-counter painkillers, yet not severe enough to

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