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    IgA Nephropathy: Facts and Treatments
    IgA Nephropathy: Facts and Treatments
    IgA Nephropathy: Facts and Treatments
    Ebook73 pages33 minutes

    IgA Nephropathy: Facts and Treatments

    By John Smith

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    About this ebook

    IgA nephropathy is a chronic kidney illness that sometimes first appears during puberty and in young adults, affecting three times as many men as women. It is also known as IgAN, Berger’s disease, synpharyngitic glomerulonephritis and IgA nephritis.
    The disease is a form of glomerulonephritis - a condition where the kidneys’ glomeruli become inflamed. It typically follows an upper respiratory infection or a gastrointestinal infection. The disease is the most common type of glomerulonephritis.
    If you or a loved one is suffering from IgA nephropathy, this book outlines the facts of the disease and provides an indispensable reference for treatment options.

    LanguageEnglish
    PublisherAndale LLC
    Release dateOct 26, 2011
    ISBN9781465747068
    IgA Nephropathy: Facts and Treatments
    Author

    John Smith

    John was born in Norwich, Norfolk from a merchant family. He made his first dives among the wrecks on the east coast of the North Sea. For few years he worked on British oil rigs and then moved to Sharm El Sheikh in Egypt where he worked as an underwater guide. After he moved to Thailand and then to the Philippines. He now lives in Florida where he is a diver and writes novels. His articles on diving and marine biology have been published in many magazines

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      Book preview

      IgA Nephropathy - John Smith

      IGA Nephropathy: Facts and Treatments

      John Smith MA

      M Awad MD (Ed.)

      Smashwords Edition

      ****

      Copyright 2011 John Smith M, M Awad MD

      Smashwords Edition, License Notes

      This ebook is licensed for your personal enjoyment only. This ebook may not be re-sold or given away to other people. If you would like to share this book with another person, please purchase an additional copy for each recipient. If you’re reading this book and did not purchase it, or it was not purchased for your use only, then please return to Smashwords.com and purchase your own copy. Thank you for respecting the hard work of this author.

      Contents

      One: Introduction:

      Two: Symptoms and Signs

      Three: Causes

      Four: Related Disorders:

      Five: Diagnosis and Treatment:

      Six: Information on Investigational Therapies

      Seven: Organizations related to IgA Nephropathy

      Eight: How the Adrenals and Kidneys Work

      Nine: Glossary of Medical Terms

      Appendix A: Internet Resources / Further Reading

      References

      One: Introduction

      IgA nephropathy is a chronic kidney illness that sometimes first appears during puberty and in young adults, affecting three times as many men as women. It is also known as IgAN, Berger’s disease, synpharyngitic glomerulonephritis and IgA nephritis. IgA nephropathy gets its name because Immunoglobulin A (IgA) deposits in the renal glomerulus - a capillary tuft that is the first step in filtering blood for urine production.

      The disease is a form of glomerulonephritis - a condition where the kidneys’ glomeruli become inflamed. It typically follows an upper respiratory infection or a gastrointestinal infection. The disease is the most common type of glomerulonephritis.

      IgA nephropathy was first described by Heberden in 1801, when he noted that a five-year-old child had hematuria, purpura on the legs, abdominal pain and hematochezia (passage of fresh blood from the anus). However, it wasn’t until 1968 that Jean Berger and Hinglais described IgA deposits in the glomerulus. In the past, IgA nephropathy was thought to be a benign disease. However, long term studies have shown that the disease is far from benign - it frequently advances to renal failure in 25 to 30 percent of patients over a 20 year period. Renal failure may occur 30 years or more after the initial infection. Remission is, unfortunately, rare: only 5 percent of cases will fully recover. However, ten year survival rates are fairly high, at between 80 and 90 percent.

      Two: Symptoms and signs

      IgA nephropathy commonly has no symptoms at all - you may have a routine urinalysis where the disease is picked up. The primary symptom is hematuria -- the passing of blood in your urine. This could be accompanied by pain in the loins. The first characteristic symptom of the disease is blood in the urine due to acute nephritis or glomerulonephritis - inflammation of the kidneys. Hematuria occurs in about 40 to 50 percent of patients and usually occurs within a very short period of time - one to two days -- from the onset of the upper respiratory tract infection. There's frequently proteinuria -- loss of protein in the urine -- with slowly progressive changes in the kidneys. Proteinuria occurs in about 20 to 30 percent of patients (however, this symptom usually occurs in older patients).

      People with this condition may rarely show features of hypertension -- raised blood pressure - or edema in the illness’s first phase. Less than 5 percent of patients present with nephritic syndrome

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