Everand Logo

Welcome to Everand!

  • Discover millions of ebooks, audiobooks, and so much more with a free trial

    Only $11.99/month after trial. Cancel anytime.

    Unavailable
    NGF and Related Molecules in Health and Disease
    Unavailable
    NGF and Related Molecules in Health and Disease
    Unavailable
    NGF and Related Molecules in Health and Disease
    Ebook1,604 pages17 hours

    NGF and Related Molecules in Health and Disease

    ()

    Currently unavailable

    Currently unavailable

    About this ebook

    The book highlights different aspects of current understanding of neurotrophin-receptor signal transduction pathways, including the signaling endosome hypothesis. Findings on the synaptotrophic potential of NGF and related neurotrophins, neurotrophin involvement in neuronal stem cell biology, biological activity of the NGF precursor proNGF, and nociception- and antinociception-associated activity of NGF and/or BDNF are also presented and discussed.



    Several chapters deal with the involvement of various neurotrophins in the control of different nonneuronal processes, such as immune, inflammatory and allergic reactions, tissue repair and wound healing. The findings showed that neurotrophins play important roles in the pathobiology of a surprising variety of seemingly unrelated non-neurological diseases, including bronchial asthma, rheumatoid arthritis, systemic sclerosis, hair growth disorders, psoriasis, corneal and skin ulcers, atherosclerosis, metabolic syndrome, crush syndrome, and Behçet's disease. There are also chapters on the involvement of NGF and related molecules in neurological diseases, including Huntington's disease, the multiple sclerosis-like model of experimental allergic encephalomyelitis, peripheral neuropathies, neuroblastoma, Parkinson's disease, Alzheimer's disease, and even motion sickness syndrome, also psychiatric disorders, including depression and schizophrenia. Finally, potential important therapeutic benefits are presented, for diabetic neuropathy, gastrointestinal dysmotility, CNS neurodegenerative disease, spinal cord injuries, cutaneous and corneal ulcers, as well as peripheral ischemic vasculopathy.

    LanguageEnglish
    PublisherElsevier Science
    Release dateDec 10, 2003
    ISBN9780080497501
    Unavailable
    NGF and Related Molecules in Health and Disease

    Related to NGF and Related Molecules in Health and Disease

    Related ebooks

    Biology For You

    View More
    View More

    Related podcast episodes

    Related articles

    • Article

      These Molecules May Drive Brain Inflammation

      May 1, 2017

      While brain inflammation is a major part of neurodegenerative diseases including multiple sclerosis, Alzheimer’s, Parkinson’s, ALS, and others, comparatively little is known about its causes and exact role in various diseases. Now, researchers may ha

      2 min read

    • Article

      Faulty Glial Cells Are At The Center Of Huntington’s Disease

      Dec 18, 2018

      Support cells in the brain are key contributors to Huntington’s disease, according to a new study. The research gives scientists a clearer picture of what is happening in the brains of people with the disease and lays out a potential path for treatme

      3 min read

    • Article

      Antioxidants May Interrupt Parkinson’s Nerve Degeneration

      Sep 12, 2017

      New research may have found a cause of nerve degeneration in patients with Parkinson’s disease and a potential treatment that can interrupt the process. Scientists identified a toxic cascade that leads to neuronal degeneration in patients with Parkin

      2 min read

    • Article

      MicroRNA Snippets May Warn Of Alzheimer’s Down The Road

      Jun 29, 2018

      Tiny snippets of genetic material called microRNA may offer a way to detect conditions such as Alzheimer’s disease earlier, according to a new study. Researchers have discovered that changes in microRNA are detectable in mice long before they start t

      2 min read

    • Article

      These Brains Cells Don’t Die, But They Do Move

      Jun 22, 2018

      Scientists have thought for decades that one area of the brain simply disappears during human development. Now, genetic similarities between cells in the subplate and neurons linked to autism suggest a different scenario. In a new paper, researchers

      2 min read

    • Article

      How Light Affects The Gut

      Sep 27, 2020

      How Light Affects The Gut
      1 min read

    • Article

      Research Using Brains-in-a-dish Forces A Radical Rethinking Of Huntington’s Disease

      Dec 10, 2019

      The new understanding, that Huntington's may start before birth, is surprising because it has long seemed like a prototypical neurodegenerative disease that doesn't strike until adulthood.

      6 min read

    • Article

      How Motor Neurons Falter in Spinal Muscular Atrophy

      May 18, 2017

      Scientists have discovered a chain of events in which the mutation that causes spinal muscular atrophy disrupts motor neurons and their communication with muscle. The discovery follows US approval in December of the first treatment for the disease th

      2 min read

    • Article

      This Disruption Contributes to Muscle Paralysis

      Dec 8, 2017

      New research marks a step forward in the quest to find the cause of amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig’s disease. In the cells of flies, mice, and humans with ALS, scientists have pinpointed a process that collapses when a

      3 min read

    • Article

      ‘Powerhouse’ Gene Plays Key Role In Kidney Failure

      Mar 21, 2024

      Scientists have identified a gene that plays a crucial role in regulating energy supply to cells that drive kidney failure, according to a new study. The discovery concerning the gene, named WWP2, offers a new target for therapies aimed at mitigating

      2 min read

    Related categories

    Reviews for NGF and Related Molecules in Health and Disease

    0 ratings

    0 ratings0 reviews

    What did you think?

    Tap to rate

    Review must be at least 10 words