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Handbook of Process Chromatography: Development, Manufacturing, Validation and Economics
Unavailable
Handbook of Process Chromatography: Development, Manufacturing, Validation and Economics
Unavailable
Handbook of Process Chromatography: Development, Manufacturing, Validation and Economics
Ebook318 pages9 hours

Handbook of Process Chromatography: Development, Manufacturing, Validation and Economics

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About this ebook

This book will update the original edition published in 1997. Since the publication of the first edition, the biotechnology and biologics industries have gained extensive knowledge and experience in downstream processing using chromatography and other technologies associated with recovery and purification unit operations. This book will tie that experience together for the next generation of readers.

Updates include:

- sources and productivity
- types of products made today
- experiences in clinical and licensed products
- economics
- current status of validation
- illustrations and tables
- automated column packing
- automated systems

New topics include:

- the use of disposables
- multiproduct versus dedicated production
- design principles for chromatography media and filters
- ultrafiltration principles and optimization
- risk assessments
- characterization studies
- design space
- platform technologies
- process analytical technologies (PATs)
- biogenerics
- comparability assessments

Key Features:

- new approaches to process optimiaztion
- use of patform technologies
- applying risk assessment to process design
LanguageEnglish
Release dateDec 8, 2007
ISBN9780080554518
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Handbook of Process Chromatography: Development, Manufacturing, Validation and Economics
Author

Gunter Jagschies

Dr. Jagschies is a 30-plus year employee at GE Healthcare Life Sciences and a globally recognized expert in bioprocessing. He has published numerous papers and two books on the development, manufacturing and economics of biotherapeutics, and in 2012 he received the BioProcess International award “Thought Leader of the Decade”.

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