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Centrifugal Separations in Biotechnology
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About this ebook
This book is the first devoted to centrifugal separation in biotechnology. It is of value to
professionals in the chemical, bioprocess, and biotech sectors, and all those concerned with bioseparation, bioprocessing, unit-operations and process engineering.
Key topics covered include a full introduction to centrifugation, sedimentation and separation; detailed coverage of centrifuge types, including batch and semi-batch centrifuges, disk-stack and tubular decanter centrifuges; methods for increasing solids concentration; laboratory and pilot testing of centrifuges; selection and sizing centrifuges; scale-up of equipment, performance prediction and analysis of test results using numerical simulation.
professionals in the chemical, bioprocess, and biotech sectors, and all those concerned with bioseparation, bioprocessing, unit-operations and process engineering.
Key topics covered include a full introduction to centrifugation, sedimentation and separation; detailed coverage of centrifuge types, including batch and semi-batch centrifuges, disk-stack and tubular decanter centrifuges; methods for increasing solids concentration; laboratory and pilot testing of centrifuges; selection and sizing centrifuges; scale-up of equipment, performance prediction and analysis of test results using numerical simulation.
- A comprehensive guide to centrifuges, their optimal development and operation in the biotechnology industry
- Applications for the separation of proteins, DNA, mitochondria, ribosomes, lysosomes and other cellular elements
- Provides detailed process information and data to assist in the development of particular processes from existing systems
- Explores the commercial applications of centrifuges in biotechnology
- Guidance on troubleshooting and optimizing centrifuges
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Author
Wallace Woon-Fong Leung
Dr. Wallace Woon-Fong Leung is a Distinguished Research Professor from Hong Kong Polytechnic University. He was formerly Chair Professor of Innovative Products and Technologies (2005-2020) and founder and Director of Research Institute of Innovative Products and Technologies (2005-2011) in the same University. He has worked in filtration and separation for 45 years both in industry in the US and academia in Hong Kong from membrane filtration, sedimentation, vacuum filter, centrifugation, air filtration, and photocatalytic oxidation. He has 52 US patents, single-authored 3 books, several handbook chapters, and over 80 SCI papers. He has trained many engineers and graduated 9 PhD students. He is a fellow respectively of AICHE, ASME, AFS, HKIE, and Hong Kong Academy of Engineering Sciences. He is the Chairman of International Delegation on Filtration, 2016 – 2022, with 13 member countries worldwide and Chairman of the 9th and 13th World Filtration Congress in 2004 and 2022, respectively. He received his BSc from Cornell, and both SMME and ScD from MIT. In 2015, he has received the Frank Tiller Award for his lifetime contribution in engineering and education on filtration and separation technologies by the American Filtration and Separations Society. Dr. Leung is also a multidisciplinary engineer, scientist, and educator with international academic and industrial experiences. During the COVID-19 pandemic, he has deployed his invented nanofiber technologies in mass production of highly protective, highly breathable facemasks for the public railroad.
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