Rating: 0 out of 5 stars
0 ratings
Unavailable
Unavailable
Unavailable
Ebook948 pages10 hours
Biophysical Characterization of Proteins in Developing Biopharmaceuticals
Rating: 0 out of 5 stars
()
Currently unavailable
Currently unavailable
About this ebook
Biophysical Characterization of Proteins in Developing Biopharmaceuticals is concerned with the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure this book takes the reader on a journey on how to best achieve this goal using the key relevant and practical methods commonly employed in the biopharmaceutical industry today as well as up and coming promising methods that are now gaining increasing attention.
As a general resource guide this book has been written with the intent to help today’s industrial scientists working in the biopharmaceutical industry or the scientists of tomorrow who are planning a career in this industry on how to successfully implement these biophysical methodologies. In so doing a keen focus is placed on understanding the capability of these methodologies in terms of what information they can deliver. Aspects of how to best acquire this biophysical information on these very complex drug molecules, while avoiding potential pitfalls, in order to make concise, well informed productive decisions about their development are key points that are also covered.
- Presents the reader with a clear understanding of the real world issues and challenges in using these methods.
- Highlights the capabilities and limitations of each method.
- Discusses how to best analyze the data generated from these methods.
- Points out what one needs to look for to avoid making faulty conclusions and mistakes.
- In total it provides a check list or road map that empowers the industrial scientists as to what they need to be concerned with in order to effectively do their part in successfully developing these new drugs in an efficient and cost effective manner.
Unavailable
Related to Biophysical Characterization of Proteins in Developing Biopharmaceuticals
Related ebooks
Biophysical Methods for Biotherapeutics: Discovery and Development Applications Systems Biology in Drug Discovery and Development Rating: 0 out of 5 stars0 ratingsRegulated Bioanalytical Laboratories: Technical and Regulatory Aspects from Global Perspectives Rating: 0 out of 5 stars0 ratingsSurfactants in Biopharmaceutical Development Rating: 0 out of 5 stars0 ratingsApproaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics Rating: 0 out of 5 stars0 ratingsThe Path from Biomarker Discovery to Regulatory Qualification Rating: 0 out of 5 stars0 ratingsMolecular Biological Markers for Toxicology and Risk Assessment Rating: 0 out of 5 stars0 ratingsEssential Chemistry for Formulators of Semisolid and Liquid Dosages Rating: 5 out of 5 stars5/5Metabolomics for Biomedical Research Rating: 0 out of 5 stars0 ratingsBiotransformation and Metabolite Elucidation of Xenobiotics: Characterization and Identification Rating: 0 out of 5 stars0 ratingsPediatric Non-Clinical Drug Testing: Principles, Requirements, and Practice Rating: 0 out of 5 stars0 ratingsAnalysis of Aggregates and Particles in Protein Pharmaceuticals Rating: 0 out of 5 stars0 ratingsMolecular Microbial Diagnostic Methods: Pathways to Implementation for the Food and Water Industries Rating: 0 out of 5 stars0 ratingsConcepts and Techniques in Genomics and Proteomics Rating: 0 out of 5 stars0 ratingsClinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation Rating: 0 out of 5 stars0 ratingsTechniques for Downstream process for Biologic Drugs and Vaccines Rating: 0 out of 5 stars0 ratingsEssentials of Botanical Extraction: Principles and Applications Rating: 5 out of 5 stars5/5In Vitro Toxicology Rating: 0 out of 5 stars0 ratingsIntroduction to Biologic and Biosimilar Product Development and Analysis Rating: 0 out of 5 stars0 ratingsMutagenicity: Assays and Applications Rating: 5 out of 5 stars5/5Glucose Monitoring Devices: Measuring Blood Glucose to Manage and Control Diabetes Rating: 0 out of 5 stars0 ratingsThe Design and Development of Novel Drugs and Vaccines: Principles and Protocols Rating: 0 out of 5 stars0 ratingsMicrofluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery Rating: 0 out of 5 stars0 ratingsBiological Drug Products: Development and Strategies Rating: 0 out of 5 stars0 ratingsMonoclonal Antibodies: Physicochemical Analysis Rating: 0 out of 5 stars0 ratingsBiotechnology in Healthcare, Volume 2: Applications and Initiatives Rating: 0 out of 5 stars0 ratingsBiomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation Rating: 0 out of 5 stars0 ratingsPharmaceutical Biotechnology in Drug Development Rating: 0 out of 5 stars0 ratingsPredictive Approaches in Drug Discovery and Development: Biomarkers and In Vitro / In Vivo Correlations Rating: 0 out of 5 stars0 ratings
Medical For You
The Lost Book of Simple Herbal Remedies: Discover over 100 herbal Medicine for all kinds of Ailment Inspired By Barbara O'Neill Rating: 0 out of 5 stars0 ratingsHolistic Herbal: A Safe and Practical Guide to Making and Using Herbal Remedies Rating: 4 out of 5 stars4/5The Hormone Reset Diet: Heal Your Metabolism to Lose Up to 15 Pounds in 21 Days Rating: 4 out of 5 stars4/5Adult ADHD: How to Succeed as a Hunter in a Farmer's World Rating: 4 out of 5 stars4/5The Vagina Bible: The Vulva and the Vagina: Separating the Myth from the Medicine Rating: 5 out of 5 stars5/5Period Power: Harness Your Hormones and Get Your Cycle Working For You Rating: 4 out of 5 stars4/5Rewire Your Brain: Think Your Way to a Better Life Rating: 4 out of 5 stars4/5Mediterranean Diet Meal Prep Cookbook: Easy And Healthy Recipes You Can Meal Prep For The Week Rating: 5 out of 5 stars5/5The Diabetes Code: Prevent and Reverse Type 2 Diabetes Naturally Rating: 4 out of 5 stars4/5What Happened to You?: Conversations on Trauma, Resilience, and Healing Rating: 4 out of 5 stars4/5The 40 Day Dopamine Fast Rating: 4 out of 5 stars4/5The Amazing Liver and Gallbladder Flush Rating: 5 out of 5 stars5/5Tight Hip Twisted Core: The Key To Unresolved Pain Rating: 4 out of 5 stars4/5ATOMIC HABITS:: How to Disagree With Your Brain so You Can Break Bad Habits and End Negative Thinking Rating: 5 out of 5 stars5/5Healthy Gut, Healthy You: The Personalized Plan to Transform Your Health from the Inside Out Rating: 4 out of 5 stars4/5Working Stiff: Two Years, 262 Bodies, and the Making of a Medical Examiner Rating: 4 out of 5 stars4/5Herbal Healing for Women Rating: 4 out of 5 stars4/5The Art of Dying Well: A Practical Guide to a Good End of Life Rating: 4 out of 5 stars4/5Woman: An Intimate Geography Rating: 4 out of 5 stars4/5The Big Fat Surprise: Why Butter, Meat and Cheese Belong in a Healthy Diet Rating: 4 out of 5 stars4/5Women With Attention Deficit Disorder: Embrace Your Differences and Transform Your Life Rating: 5 out of 5 stars5/5Summary of Dr. Gundry's Diet Evolution: Turn off the Genes That Are Killing You and Your Waistline Rating: 3 out of 5 stars3/5Gut: The Inside Story of Our Body's Most Underrated Organ (Revised Edition) Rating: 4 out of 5 stars4/5Hidden Lives: True Stories from People Who Live with Mental Illness Rating: 4 out of 5 stars4/5
Related podcast episodes
C-Suite Quick Takes: OIS Goes Behind the Scenes with Four Emerging Biotech Companies 0% found this document usefulThe ESMO 2022 Clinical Practice Guidelines for use of systemic therapy in advanced thyroid care 0% found this document usefulStem Cell Therapy and Personal Stem Cell Banking with Sean Berman and Kevin Ferber : 1058 0% found this document usefulNeogen: Why AOAC? 0% found this document usefulImproving the State of Cell Isolation & Recovery with Andrew Breite from VitaCyte 0% found this document usefulMedical Information 0% found this document usefulOIS Retina 2022: How to Execute New Treatments for Dry AMD and GA 0% found this document usefulEp. 80. Bob Gravani: Unconscious Competence in Food Safety 0% found this document usefulPayerTalkCE Presents: Applying Real-World Experience to Better Manage the Use of Oncology Biosimilars 0% found this document useful
Related articles
Opinion: Bringing Order To The ‘Wild Frontier’ Of Microbiome Medicine STATArticle
Opinion: Bringing Order To The ‘Wild Frontier’ Of Microbiome Medicine
Oct 2, 2018
When it comes to #microbiome medicine, @US_FDA and @NIH need to create a solid, science-based regulatory framework to help realize the promise of living drugs.
4 min readOpinion: From Bench To Bedside, Biologics Require Excellence At Every Stage STATArticle
Opinion: From Bench To Bedside, Biologics Require Excellence At Every Stage
Feb 13, 2020
Quality and trust go together. As an industry, biologic manufacturers must deliver on quality. Public trust of sophisticated biological products will follow.
3 min readOpinion: Real-world Data Can Help Make Better Drugs And Do It Faster STATArticle
Opinion: Real-world Data Can Help Make Better Drugs And Do It Faster
May 2, 2018
Relying solely on clinical trials to demonstrate the safety and effectiveness of new drugs can be risky. Real-world data can help.
4 min readBedside Drug Production Will Truly Enable Personalized Medicine STATArticle
Bedside Drug Production Will Truly Enable Personalized Medicine
Jun 19, 2017
4 min readOpinion: Real-world Evidence Is Changing The Way We Study Drug Safety And Effectiveness STATArticle
Opinion: Real-world Evidence Is Changing The Way We Study Drug Safety And Effectiveness
Jan 29, 2019
Instead of waiting for fleshed-out protocols for using real-world evidence, pharmaceutical companies should dive in now using a commonsense approach that relies on rigor and reason.
4 min readOpinion: Manufacturing: The Next Breakthrough In Gene Therapy STATArticle
Opinion: Manufacturing: The Next Breakthrough In Gene Therapy
Dec 18, 2019
As the race heats up to bring gene therapy to market, breakthroughs in manufacturing are often the key — or break down the barrier — to delivering these therapies to…
3 min readThe World’s Best Hospitals2023 Newsweek InternationalArticle
The World’s Best Hospitals2023
Mar 10, 2023
9 min readThe World’s Best Hospitals2023 NewsweekArticle
The World’s Best Hospitals2023
Mar 10, 2023
9 min readWheeler’s Breathtaking Ignorance of Science, in One Comment Union of Concerned ScientistsArticle
Wheeler’s Breathtaking Ignorance of Science, in One Comment
Jun 6, 2019
4 min readOpinion: Synthetic Control Arms Can Save Time And Money In Clinical Trials STATArticle
Opinion: Synthetic Control Arms Can Save Time And Money In Clinical Trials
Feb 5, 2019
Synthetic control arms aren't the solution to all of the challenges facing randomized trials, but they represent a great way for drug development companies to start using real-world evidence.
4 min readThe World’s Best Hospitals 2024 NewsweekArticle
The World’s Best Hospitals 2024
Mar 8, 2024
10 min readThe World’s Best Hospitals 2024 Newsweek InternationalArticle
The World’s Best Hospitals 2024
Mar 8, 2024
10 min readProbiotics Are Touted As Good For The Gut. They May Be Trouble For The Immune System STATArticle
Probiotics Are Touted As Good For The Gut. They May Be Trouble For The Immune System
Apr 2, 2019
Some scientists worry probiotics aren’t as innocuous as they seem — and might be affecting the way other medicines work in the body.
4 min readWhat to Expect at FDA’s Vaccine Advisory Committee Meeting Union of Concerned ScientistsArticle
What to Expect at FDA’s Vaccine Advisory Committee Meeting
Oct 19, 2020
5 min readSFI Health — Home of Flordis WellBeingArticle
SFI Health — Home of Flordis
Sep 13, 2023
3 min readTHE WORLD’S BEST Specialized Hospitals 2023 NewsweekArticle
THE WORLD’S BEST Specialized Hospitals 2023
Sep 16, 2022
72 min readOpinion: FDA Should Use Its Existing Program To Qualify New Tools For Drug Safety Testing STATArticle
Opinion: FDA Should Use Its Existing Program To Qualify New Tools For Drug Safety Testing
Aug 20, 2019
3 min readOpinion: China Isn’t Yet Ready To Conduct Clinical Trials For The Pharma Industry STATArticle
Opinion: China Isn’t Yet Ready To Conduct Clinical Trials For The Pharma Industry
Aug 3, 2018
3 min readWorld’s Best Specialized Hospitals 2001 Newsweek InternationalArticle
World’s Best Specialized Hospitals 2001
Nov 13, 2020
9 min readProbiotics Studies Often Don’t Disclose Safety Data Or Risks, Report Finds STATArticle
Probiotics Studies Often Don’t Disclose Safety Data Or Risks, Report Finds
Jul 16, 2018
Many studies of probiotics fail to adequately report on adverse events, a new analysis finds, making it impossible to broadly conclude whether the products are safe.
3 min readFunctional Pathology in Australia The Art of HealingArticle
Functional Pathology in Australia
Dec 1, 2019
7 min readOpinion: Two Words To Help Ned Sharpless Revolutionize Clinical Trials: Data Standards STATArticle
Opinion: Two Words To Help Ned Sharpless Revolutionize Clinical Trials: Data Standards
May 13, 2019
4 min readOpinion: Novartis Violated FDA’s Sacred Principle: In God We Trust, All Others Must Bring Data STATArticle
Opinion: Novartis Violated FDA’s Sacred Principle: In God We Trust, All Others Must Bring Data
Aug 14, 2019
6 min readWorld’s Best Specialized Hospitals 2021 NewsweekArticle
World’s Best Specialized Hospitals 2021
Nov 13, 2020
9 min readOpinion: Combatting Misinformation On Biosimilars And Preparing The Market For Them Can Save The U.S. Billions STATArticle
Opinion: Combatting Misinformation On Biosimilars And Preparing The Market For Them Can Save The U.S. Billions
Jun 19, 2019
For more than a decade, biosimilars have flourished in Europe. That hasn't happened in the U.S. because of misinformation and poor market preparation.
5 min readThe Parker Institute Touts Early Results In Pancreatic Cancer Trial — And A New Model To Accelerate Drug Development STATArticle
The Parker Institute Touts Early Results In Pancreatic Cancer Trial — And A New Model To Accelerate Drug Development
Mar 31, 2019
3 min readWhy Are Elite Athletes Different Than The Rest Of Us? Take A Look At Their Microbes STATArticle
Why Are Elite Athletes Different Than The Rest Of Us? Take A Look At Their Microbes
Jun 24, 2019
Elite athletes really are different from you and me. Or, at least their gut microbes are. Scientists who analyzed stool samples of 15 runners a week before and after they competed in the 2015 Boston Marathon found unusually high levels of one particu
3 min readOpinion: All Study Participants Have A Right To Know Their Own Results. My Lab Has Been Doing That For Years STATArticle
Opinion: All Study Participants Have A Right To Know Their Own Results. My Lab Has Been Doing That For Years
Sep 5, 2018
Giving study participants their individual results can drive greater public participation in research, increased support for science, and better health.
6 min readCell Therapies – Australia Playing Catch Up? AQ: Australian QuarterlyArticle
Cell Therapies – Australia Playing Catch Up?
Sep 30, 2016
13 min readThe Latest Word On PROBIOTICS Your FamilyArticle
The Latest Word On PROBIOTICS
Jun 17, 2019
2 min read
Reviews for Biophysical Characterization of Proteins in Developing Biopharmaceuticals
Rating: 0 out of 5 stars
0 ratings
0 ratings0 reviews