The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations
5/5
()
About this ebook
A volume in the Emerging Issues in Analytical Chemistry series, The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations provides analytical chemistry methods that address the latest issues surrounding cannabis-based products. The plethora of marketed strains of cannabis and cannabinoid-containing products, combined with the lack of industry standards and labelling requirements, adds to the general perception of poor quality control and limited product oversight. The methods described in this leading-edge volume help to support the manufacturing, labelling, and distribution of safe and consistent products with known chemical content and demonstrated performance characteristics. It treats analytical chemistry within the context of the diverse issues surrounding medicinal and recreational cannabis in a manner designed to foster understanding and rational perspective in non-scientist stakeholders as well as scientists who are concerned with bringing a necessary degree of order to a field now characterized by confusion and contradiction.
- Addresses current and emerging analytical chemistry methods - an approach that is unique among the literature on this topic
- Presents information from a broad perspective of the issues in a single compact volume
- Employs language comprehensible to non-technical stakeholders as well as to specialists in analytical chemistry
Brian F. Thomas
Brian F. Thomas earned his doctoral degree in 1992 from the Medical College of Virginia/Virginia Commonwealth University, USA. He then joined Research Triangle Institute and assumed the role of Principal Investigator on National Institute on Drug Abuse (NIDA) research contracts titled “Purity Specifications, Storage and Distribution for Medications Development, “Preparation and Distribution of Research Drug Products, and “Production, Analysis and Distribution of Cannabis, Marijuana Cigarettes and Related Materials. Serving in these roles, he coordinated the preparation and analysis of research drugs and substance abuse treatment medications at RTI for over 28 years. In addition to contract research, Dr. Thomas served as Principal Investigator on several NIDA R01 grant-funded research awards involving the characterization of cannabinoid ligand-receptor interactions and their relationship to in vivo pharmacological effects. In 2019, he joined Canopy Growth Corporation as Senior Director, Analytical Chemistry, Discovery Sciences, and Pharmaceutics, where he had management oversight of drug substance and product testing to support preclinical and clinical studies of cannabinoids in accordance with regulatory guidance. He also directed the integration of medicinal chemistry and in vitro pharmacological screening approaches to support development of consumer products and drive clinical drug discovery and therapeutic product development and commercialization efforts. He was subsequently recruited by The Cronos Group to serve as the Director of Analytical Sciences, with management oversight of scientists at production and research and development facilities in the United States, Canada, and Israel. He also engaged with the US Hemp Roundtable and other trade and scientific organizations to provide critical input to regulations and regulatory oversight by state, federal, and international regulatory authorities. He is currently providing pharmaceutical consulting services as the Principal Scientist at Empirical Pharmaceutical Services, LLC. He also serves on the Scientific Advisory Boards of Bright Green Corporation and Biopharmaceutical Research Company, two of the cannabis companies selected by the US government to grow, manufacture, and sell, legally under federal and state laws, cannabis and cannabis-related products for research, pharmaceutical applications, and export. He has authored or co-authored over 120 peer-reviewed manuscripts and numerous book chapters, coauthored a book, and served as the Series Editor of Elsevier’s Emerging Issues in Analytical Chemistry.
Related to The Analytical Chemistry of Cannabis
Related ebooks
The Endocannabinoidome: The World of Endocannabinoids and Related Mediators Rating: 0 out of 5 stars0 ratingsEssentials of Botanical Extraction: Principles and Applications Rating: 5 out of 5 stars5/5Weed Science: Cannabis Controversies and Challenges Rating: 0 out of 5 stars0 ratingsIntroduction to Biological and Small Molecule Drug Research and Development: Theory and Case Studies Rating: 5 out of 5 stars5/5Natural Products and Drug Discovery: An Integrated Approach Rating: 0 out of 5 stars0 ratingsProdrug Design: Perspectives, Approaches and Applications in Medicinal Chemistry Rating: 3 out of 5 stars3/5The Cannabinoids: Chemical, Pharmacologic, and Therapeutic Aspects Rating: 0 out of 5 stars0 ratingsTerpenes: The Magic in Cannabis Rating: 4 out of 5 stars4/5Marijuana Chemistry: Genetics, Processing, Potency Rating: 4 out of 5 stars4/5The Pot Book: A Complete Guide to Cannabis Rating: 3 out of 5 stars3/5Cannabis: Evolution and Ethnobotany Rating: 3 out of 5 stars3/5100 Best Cannabis Strains: A Pocket Guide for Medicinal and Recreational Use Rating: 5 out of 5 stars5/5Brave New Weed: Adventures into the Uncharted World of Cannabis Rating: 3 out of 5 stars3/5Marijuana Harvest: How to Maximize Quality and Yield in Your Cannabis Garden Rating: 4 out of 5 stars4/5Growing Marijuana: The Home Grower's Guide Rating: 5 out of 5 stars5/5Cannabis Sativa Volume 2: The Essential Guide to the World's Finest Marijuana Strains Rating: 0 out of 5 stars0 ratingsThe Cannabis Revolution©: What You Need to Know Rating: 0 out of 5 stars0 ratingsThe Little Book of Cannabis: How Marijuana Can Improve Your Life Rating: 4 out of 5 stars4/5Cannabis Indica Volume 3: The Essential Guide to the World's Finest Marijuana Strains Rating: 5 out of 5 stars5/5Grow Marijuana Calendar: Easy Growing Marijuana Tips, Drinks & Recipes Rating: 2 out of 5 stars2/5The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy Rating: 0 out of 5 stars0 ratingsGrowing Marijuana: How to Plant, Cultivate, and Harvest Your Own Weed Rating: 5 out of 5 stars5/5
Biology For You
Why We Sleep: Unlocking the Power of Sleep and Dreams Rating: 4 out of 5 stars4/5Dopamine Detox: Biohacking Your Way To Better Focus, Greater Happiness, and Peak Performance Rating: 3 out of 5 stars3/5Gut: The Inside Story of Our Body's Most Underrated Organ (Revised Edition) Rating: 4 out of 5 stars4/5Sapiens: A Brief History of Humankind Rating: 4 out of 5 stars4/5The Sixth Extinction: An Unnatural History Rating: 4 out of 5 stars4/5The Obesity Code: the bestselling guide to unlocking the secrets of weight loss Rating: 4 out of 5 stars4/5Peptide Protocols: Volume One Rating: 4 out of 5 stars4/5The Grieving Brain: The Surprising Science of How We Learn from Love and Loss Rating: 4 out of 5 stars4/5The Winner Effect: The Neuroscience of Success and Failure Rating: 5 out of 5 stars5/5The Soul of an Octopus: A Surprising Exploration into the Wonder of Consciousness Rating: 4 out of 5 stars4/5A Crack In Creation: Gene Editing and the Unthinkable Power to Control Evolution Rating: 4 out of 5 stars4/5Woman: An Intimate Geography Rating: 4 out of 5 stars4/5"Cause Unknown": The Epidemic of Sudden Deaths in 2021 & 2022 Rating: 5 out of 5 stars5/5Lifespan: Why We Age—and Why We Don't Have To Rating: 4 out of 5 stars4/5A Letter to Liberals: Censorship and COVID: An Attack on Science and American Ideals Rating: 3 out of 5 stars3/5How Emotions Are Made: The Secret Life of the Brain Rating: 4 out of 5 stars4/5Lies My Gov't Told Me: And the Better Future Coming Rating: 4 out of 5 stars4/5Other Minds: The Octopus, the Sea, and the Deep Origins of Consciousness Rating: 4 out of 5 stars4/5Mother of God: An Extraordinary Journey into the Uncharted Tributaries of the Western Amazon Rating: 4 out of 5 stars4/5The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race Rating: 4 out of 5 stars4/5Suicidal: Why We Kill Ourselves Rating: 4 out of 5 stars4/5Emotional Blackmail: When the People in Your Life Use Fear, Obligation, and Guilt to Manipulate You Rating: 4 out of 5 stars4/5Anatomy and Physiology For Dummies Rating: 4 out of 5 stars4/5Anatomy 101: From Muscles and Bones to Organs and Systems, Your Guide to How the Human Body Works Rating: 4 out of 5 stars4/5The Deepest Well: Healing the Long-Term Effects of Childhood Trauma and Adversity Rating: 4 out of 5 stars4/5Morphic Resonance: The Nature of Formative Causation Rating: 4 out of 5 stars4/5The Blood of Emmett Till Rating: 4 out of 5 stars4/5Jaws: The Story of a Hidden Epidemic Rating: 4 out of 5 stars4/5Ultralearning: Master Hard Skills, Outsmart the Competition, and Accelerate Your Career Rating: 4 out of 5 stars4/5
Related categories
Reviews for The Analytical Chemistry of Cannabis
1 rating0 reviews
Book preview
The Analytical Chemistry of Cannabis - Brian F. Thomas
appreciated.
Chapter 1
The Botany of Cannabis sativa L.
Abstract
Cannabis sativa L. is among the oldest known cultivated plants, with a long history of medical use. Cannabis produces a unique class of terpenophenolic compounds called cannabinoids, 104 of which have been isolated, the major biologically active one being Δ⁹-tetrahydrocannabinol. Cannabidiol, an antiepileptic, is also important. Cannabis is an annual, normally dioecious and occasionally monoecious, wind-pollinated species and is highly allogamous (cross-fertilization) in nature. Therefore, maintaining the efficacy of selected high Δ⁹-tetrahydrocannabinol-yielding elite varieties grown from seeds under field or greenhouse conditions is very difficult. Thus, a careful screening of elite mother clones using GC-FID and their propagation using vegetative cuttings or advanced biotechnological approaches, including micropropagation, is the most suitable way to maintain quality. This chapter describes the botany, species debate, phenotype, screening of high-yielding clones using GC-FID, indoor and outdoor cultivation, micropropagation, quality assurance of propagated plants, harvesting, processing, and