Demystifying Cancer Biology: What cancer actually is and the science behind its 'success': Clarity in Science, #1
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About this ebook
Demystifying Cancer Biology is a mini-textbook with a difference – written in clear, easy-to-understand language, this eBook will break down the barriers to understanding the complex world of the cellular and molecular biology of cancer.
Cancer biology is a highly specialized subject area that is rife with jargon and acronyms, and it requires a strong foundation in understanding the processes underlying cell growth, division, survival and movement. Demystifying Cancer Biology will help the reader build this foundational knowledge through the use of everyday analogies and metaphors.
As a lecturer, I structure my cancer biology teaching around Hanahan and Weinberg's classic review article describing the six fundamental hallmarks of cancer (Hanahan and Weinberg, 2000) because it gives students a broad understanding of the science of how cancer cells successfully colonize the host. However, I often found that students struggled to understand it because of the introduction of new terminology and the heavy use of jargon.
Ever the scientist, I decided to experiment with re-writing elements of this review article as blog posts, illustrating the hallmarks of cancer using everyday analogies and metaphors to help break down their barriers to understanding. By drawing comparisons between the characteristics of cancer cells with concepts students would be familiar with, such as likening the growth of cancer cells with the process of making pizza, students were able to grasp the basic concept in advance of the lecture and more readily keep up during the lectures.
The feedback I received from my students was fantastic and so I have extended this series of blog posts and brought them together into an edited eBook, available for free to anyone with an interest in learning more about the biology of cancer.
As a writer, I am passionate about communicating science clearly. As a researcher, I love to inspire and engage my students in learning more about what cancer is and how we can find ways to prevent its spread – the major cause of cancer-related deaths. As an educator, I believe in providing a variety of learning tools to make learning accessible to all. So, I have decided to record an audio version of this mini-textbook, which readers can access by following the link inside the book.
From students in the biological sciences through to cancer healthcare professionals, Demystifying Cancer Biology is an ideal beginner's guide that will break down the barriers to understanding the complexities surrounding cancer biology and the science behind its 'success'.
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Demystifying Cancer Biology - Mhairi Morris
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Demystifying Cancer Biology:
What cancer actually is and the science behind its ‘success’
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A ‘Clarity in Science’ series
Published by Essential Cancer Education
www.essentialcancereducation.com
© 2018 Dr Mhairi A Morris
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The right of Dr Mhairi A Morris to be identified as the author of the Work has been asserted her in accordance with the Copyright, Designs and Patents Act 1988.
All rights reserved. No part of this book may be reproduced or used in any form without permission from the author, except as permitted by copyright law.
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FREE GUIDE
Get your FREE guide: the incredibly simple 3-step system to help your patients live well with cancer
https://www.essentialcancereducation.com/3steps/
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Study hard what interests you the most in the most undisciplined, irreverent and original manner possible.
— Richard Feynman
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This book is dedicated to my past and present students who love cancer biology as much as I do and have a real thirst to learn more. May you continue your ‘undisciplined, irreverent and original studying’ for all your days to come. 🤓
Hi! I’m Dr Mhairi Morris (pronounced Vari
) and I’m a Biochemistry lecturer and cancer researcher at a UK university. I love teaching – I’m a Senior Fellow of the Higher Education Academy and I was also awarded local Teacher Fellow status at my previous institution. As an academic, though, I have a particularly large bee in my bonnet about clear communication in science education. I’m not your typical academic, you see, and I’m not afraid to admit that I too get bored when reading some textbooks or journal articles. Sometimes they can be so stuffy!
A couple of years ago, I had the pleasure and honor of working with a group of teenage and young adult cancer patients as part of a research project that I’m involved with. We were exploring the use of personalized 3D printed models of patients’ tumors in helping them come to terms with their diagnosis. It was during this time in my life that I began to explore the idea of communicating cancer clearly and I set up a blog to support my teaching practice at the time, which went down a storm with my students! Since then, I’ve become passionate about explaining complex cancer science in easy-to-understand, accessible language.
Why I chose to write this particular book:
The field of cancer biology is a highly specialized subject area that is rife with jargon and acronyms, and it requires a strong foundation in understanding the processes underlying cell growth, division, survival and movement.
In their seminal paper in 2000, Hanahan and Weinberg[1]¹ described six fundamental hallmarks of cancer in a review of the literature at that time. At only 13 pages in length, it is a relatively short review, and it would take the average academic in the field less than an hour to fully digest. But then, as I’ve already alluded to, I’m not your average academic
!
I included this article as an essential recommended text for my cancer biology lectures, and I expected my students to familiarize themselves with the content. However, I found they weren’t reading it! Their feedback to me suggested that the introduction of new terminology and the heavy use of jargon rendered the paper considerably inaccessible to the average student.
So, knowing that the use of imagery, stories and metaphors are powerful learning tools, I decided to experiment with blogging. I laid out the key information to support the lectures by illustrating the hallmarks of cancer using everyday analogies and metaphors to draw comparisons between the behaviors and characteristics of cancer cells with concepts students would be familiar with. So for example, by likening the growth of cancer cells with the process of making pizza.
The feedback I received from my students was fantastic, and so I decided to bring this series of blog posts together into an edited eBook, available for free to anyone and everyone with an interest in learning