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Goodpasture Syndrome, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
Goodpasture Syndrome, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
Goodpasture Syndrome, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
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Goodpasture Syndrome, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions

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This book describes Goodpasture Syndrome, Diagnosis and Treatment and Related Diseases
Goodpasture syndrome is an infrequent and possibly life-threatening autoimmune disease.
Some forms of the disease affect just the lung or the kidney.
It produces accumulation of autoimmune proteins in the kidneys and lungs that causes damage of these organs.
Without proper diagnosis and treatment, the disorder can cause significant bleeding in the lungs, kidney inflammation and failure, and even death.
Causes
Goodpasture syndrome is a disorder of autoimmune cause.
It happens when the immune system incorrectly attacks and damages healthy body tissue.
People with this syndrome produce substances that assault a protein called collagen in the small air sacs in the lungs and the filtering units (glomeruli) of the kidneys.
These substances are called anti-glomerular basement membrane (Anti-GBM) antibodies.
The glomerular basement membrane is the part of the kidneys that helps filter waste and extra fluid from the blood.
Anti-glomerular basement membrane antibodies are antibodies attacking this membrane.
They can injure the basement membrane, which can cause kidney damage.
Occasionally, this disorder is activated by a viral respiratory infection or by breathing in hydrocarbon solvents.
In such cases, the immune system may attack organs or tissues because it incorrectly believes them for these viruses or foreign chemicals.
The immune system's faulty reaction causes bleeding in the air sacs of the lungs and inflammation in the kidney's filtering units.
Certain respiratory infections may activate the immune system.
Being exposed to hydrocarbon fumes, metallic dust, tobacco smoke, or certain drugs, such as cocaine, may also raise the risk.
Doctors thought the immune system attacks lung and kidney tissue because the body’s defenses recognize parts of those organs as foreign to the body itself.
Certain people appear to be more vulnerable to this disorder due to genetics.
This involves people who have inherited specific proteins from their parents, present as part of the HLA (human leukocyte antigens) system.
Early symptoms may be:
1. Fatigue, weakness, or lethargy
2. Nausea or vomiting
3. Loss of appetite
4. Unhealthy, pale appearance
Lung symptoms may be:
1. Coughing up blood (hemoptysis)
2. Dry cough
3. Shortness of breath or difficulty breathing
Occasionally symptoms involving the lungs can become life-threatening, producing respiratory failure, mostly if there is a lot of bleeding.
Kidney and other symptoms are:
1.Bloody urine or foamy urine
2.Burning sensation during urination
3.Nausea and vomiting
4.Pale skin
5.Swelling (edema) in any area of the body, particularly in the legs
6.Elevated blood pressure readings
7.Back pain below the ribs
Diagnosis:
1.A blood test may reveal the evidence of antibodies (proteins produced by the immune system to fight whatever it is that has been identified as a risk) that suggest the presence of the disease.
It can also reveal abnormal kidney function.
2.Urinalysis results are often abnormal, and show blood and protein in the urine, indicating kidney diseases.
3.A chest X-ray or CT scan may reveal lung damage and bleeding in the lungs.
4.A kidney biopsy may show anomalies that indicate the presence of Goodpasture syndrome.
Treatment:
1.Plasmapheresis, which eliminates harmful antibodies to help decrease inflammation in the kidneys and lungs.
2.Immunosuppressive drugs prevent the immune system from making the antibodies that injure the lungs and kidneys
3.Corticosteroids reduce inflammation and suppress the immune system.
Dialysis or kidney transplant may be done if kidney failure can no longer be treated.

TABLE OF CONTENT
Introduction
Chapter 1 Goodpasture Syndrome
Chapter 2 Causes
Chapter 3 Symptoms

LanguageEnglish
PublisherKenneth Kee
Release dateMar 28, 2019
ISBN9780463695043
Goodpasture Syndrome, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
Author

Kenneth Kee

Medical doctor since 1972.Started Kee Clinic in 1974 at 15 Holland Dr #03-102, relocated to 36 Holland Dr #01-10 in 2009.Did my M.Sc (Health Management ) in 1991 and Ph.D (Healthcare Administration) in 1993.Dr Kenneth Kee is still working as a family doctor at the age of 74However he has reduced his consultation hours to 3 hours in the morning and 2 hours inthe afternoon.He first started writing free blogs on medical disorders seen in the clinic in 2007 on http://kennethkee.blogspot.com.His purpose in writing these simple guides was for the health education of his patients which is also his dissertation for his Ph.D (Healthcare Administration). He then wrote an autobiography account of his journey as a medical student to family doctor on his other blog http://afamilydoctorstale.blogspot.comThis autobiography account “A Family Doctor’s Tale” was combined with his early “A Simple Guide to Medical Disorders” into a new Wordpress Blog “A Family Doctor’s Tale” on http://ken-med.com.From which many free articles from the blog was taken and put together into 1000 eBooks.He apologized for typos and spelling mistakes in his earlier books.He will endeavor to improve the writing in futures.Some people have complained that the simple guides are too simple.For their information they are made simple in order to educate the patients.The later books go into more details of medical disorders.He has published 1000 eBooks on various subjects on health, 1 autobiography of his medical journey, another on the autobiography of a Cancer survivor, 2 children stories and one how to study for his nephew and grand-daughter.The purpose of these simple guides is to educate patient on health disorders and not meant as textbooks.He does not do any night duty since 2000 ever since Dr Tan had his second stroke.His clinic is now relocated to the Buona Vista Community Centre.The 2 units of his original clinic are being demolished to make way for a new Shopping Mall.He is now doing some blogging and internet surfing (bulletin boards since the 1980's) startingwith the Apple computer and going to PC.The entire PC is upgraded by himself from XT to the present Pentium duo core.The present Intel i7 CPU is out of reach at the moment because the CPU is still expensive.He is also into DIY changing his own toilet cistern and other electric appliance.His hunger for knowledge has not abated and he is a lifelong learner.The children have all grown up and there are 2 grandchildren who are even more technically advanced than the grandfather where mobile phones are concerned.This book is taken from some of the many articles in his blog (now with 740 posts) A Family Doctor’s Tale.Dr Kee is the author of:"A Family Doctor's Tale""Life Lessons Learned From The Study And Practice Of Medicine""Case Notes From A Family Doctor"

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    Book preview

    Goodpasture Syndrome, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions - Kenneth Kee

    Goodpasture Syndrome,

    A

    Simple

    Guide

    To

    The Condition,

    Diagnosis,

    Treatment

    And

    Related Conditions

    By

    Dr Kenneth Kee

    M.B.,B.S. (Singapore)

    Ph.D (Healthcare Administration)

    Copyright Kenneth Kee 2019 Smashwords Edition

    Published by Kenneth Kee at Smashwords.com

    Dedication

    This book is dedicated

    To my wife Dorothy

    And my children

    Carolyn, Grace

    And Kelvin

    This book describes Goodpasture Syndrome, Diagnosis and Treatment and Related Diseases which is seen in some of my patients in my Family Clinic.

    (What You Need to Treat Goodpasture Syndrome)

    This eBook is licensed for your personal enjoyment only. This eBook may not be re-sold or given away to other people. If you would like to share this book with another person, please purchase an additional copy for each reader.

    If you’re reading this book and did not purchase it, or it was not purchased for your use only, then please return to Smashwords.com and purchase your own copy.

    Thank you for respecting the hard work of this author.

    Introduction

    I have been writing medical articles for my blog: http://kennethkee.blogspot.com (A Simple Guide to Medical Disorder) for the benefit of my patients since 2007.

    My purpose in writing these simple guides was for the health education of my patients.

    Health Education was also my dissertation for my Ph.D (Healthcare Administration).

    I then wrote an autobiolographical account of his journey as a medical student to family doctor on his other blog: http://afamilydoctorstale.blogspot.com.

    This autobiolographical account A Family Doctor’s Tale was combined with my early A Simple Guide to Medical Disorders into a new Wordpress Blog A Family Doctor’s Tale on http://kenkee481.wordpress.com.

    From which many free articles from the blog was taken and put together into 800 eBooks.

    Some people have complained that the simple guides are too simple.

    For their information they are made simple in order to educate the patients.

    The later books go into more details of medical disorders.

    The first chapter is always from my earlier blogs which unfortunately tends to have typos and spelling mistakes.

    Since 2013, I have tried to improve my spelling and writing.

    As I tried to bring the patient the latest information about a disorder or illness by reading the latest journals both online and offline, I find that I am learning more and improving on my own medical knowledge in diagnosis and treatment for my patients.

    Just by writing all these simple guides I find that I have learned a lot from your reviews (good or bad), criticism and advice.

    I am sorry for the repetitions in these simple guides as the second chapters onwards have new information as compared to my first chapter taken from my blog.

    I also find repetition definitely help me and maybe some readers to remember the facts in the books more easily.

    I apologize if these repetitions are irritating to some readers.

    Chapter 1

    Goodpasture syndrome

    What is Goodpasture syndrome?

    Goodpasture syndrome is an infrequent and possibly life-threatening autoimmune disease.

    Some forms of the disease affect just the lung or the kidney.

    Goodpasture syndrome is a rare disease that can cause rapidly worsening kidney failure and lung disease.

    It produces accumulation of autoimmune proteins in the kidneys and lungs that causes damage of these organs.

    It is believed to happen in

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