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Epidemiology
Every year:
Extra-pulmonary manifestations
Infected sputum (M. tuberculosis) Dietary products e.g. unpasturised milk, M. bovis)
Haematogenous spread
Secondry to pulmonary TB
Pathogenesis
After ingestion the organism is trapped in the
Peyers patches
It
undergoes inflammatory enlargement Leads to transverse mucosal ulceration Element of endarteritis Ultimately may lead to bowel perforation
Mesenteric lymph node infected Enlarge and caseate Intra abdominal abscess formation
Pathogenesis
Fibrosis may follow leading to napkin ring
strictures Extensive inflammation of submucosa and subserosa at ICJ hyperplastic form Adjacent bowel loops, mesentery, and nodes adhere a mass intestinal cocoon
Pathogenesis
Peritoneal involvement takes the form of the
numerous tubercles on the peritoneum and intestine Omentum thickens to form a rolled-up omentum Ascites is usually present
Pathogenesis
Haematogenous involvement presents as
multiple parenchymal abcesses with organomegaly of the liver, spleen, and pancreas. Contagious spread from the
Spine Genitourinary tract Parietal wall Retro peritoneum
Peritoneal
Wet type: Ascites Generalized Loculated Dry plastic Mesenteric thickening Caseous lymph node Fibrous adhesions
Peritoneal
Mesenteric Involvement
Solid Organ