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SYLLABUS OVERVIEW FOR GPAT/NIPER.

PHARMACEUTICS:

Lachman chapter 1 to 7 are important. Chapter 8, 11 22 are to be done from this book.

Tables on page number are important 27, 37,44,98, 151,165,174,321,357(only ingredients),416 (onlyingredients),419,434,453,463,467,508,514,515518,521,522,551570(names only), 621,631, 634, 642, 646 (tricky question like most permeable can be asked), 648.

Martin if you read subramanyam whole, then do chapter 1, and last 2 chapters (biomaterials and delivery systems from it.) Brahmankar whole book, read units of various parameters. CDDS. Remember various models. Cosmetics - remember only general things from mitthal. R. M Mehta posology, calculations are important. Cooper-gun read method for sterilization of various injections given at the end of book.

Containers, surgical instruments ans sterilization atleast see if u get time.

Extra stability testing, ICH guidelines, drug approval process like NDA, ANDA, Orange book. Intellectual property rights (NIPER only).

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What is being studied in NIPER is also asked.(THAT LEAVE TO US) GMP guidelines.

PHARMACOLOGY:

Rang and Dale remains the standard book for GPAT/NIPER. (Do all important tables from it.) K.D Tripathi see heamatology, cancer, antibiotics, disinfectants and vaccines from it. See adverse drug reactions from Roger-Walker book. Clical trials. Pharmacological classification from KDT only.

MEDICINAL CHEMISTRY:

Wilson read only following things:

-structures of important drugs(S) and their starting material.(SM)

Dapsone, Isoniazid, Etahmbutol, Pyrizinamide, Metronidazole, Methoxy Penicillin, Chloroquine, Ampicilin, Chlorpromazine, Haloperidol, Diazepam. Glutethimide, Phenobarbitone, Nikethamide, Isoprenaline, Ephedrine, Propranalol, Neostigmeine, Furosemide, Hydrochlorthiazide, Lignocaine, Procaine, Diphenhydramin, Pethidine, Indomethacin, Phenylbutazone, Thyroxine,Acetozolamide, Thiotepa, Cloxacillin.Nephazoline, Phentolamine, Streptomycin, Penicillin, Nitrofurantoin,

Thiobendazole, Digitoxin, Atropine, Cocaine, Methotrexate, Trimethoprim, Clonidine, Phentoin, 08401782004, 07814727760 Best Luck

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Papverine, Quinine, Chlorthalidone, Hydralazine.Mepyramine, Promathazine,Cyclizine, Cetrizine, Cyproheptadine, Triprolidine, Astemizole, Cimetidine, Ranitine, Antazoline, Tripelennamine, Benzocaine, Ketamine, Thiopentone,Valproic Acid, Carbamazepine, Methohexital, Amitryptiline, Testosterone, Progesterone, Hydrocortisone, Diethylstilbesterol, Dienesterol, Ethacrynic Acid, Allopurinol, Captopril, Proparanalol, Guanethidine, Dextripropoxyphene. Ibuprofen , Fentanyl, Indomathacin, Prednsolone, Betamethasone, Triamicinolone, Cortisone, Estradiol, Cholesterol, Stanozolol, Probenecid, Ketoconazole, Amphotericin, Nystatin, Primaquin, Artemisin, Gentamicin,Neomycin, Erythromycin,

Ampicilin,Amoxicillin.Tranyl Cypromine, Chloramphenicol, Metronidazole, Mebendazole,Thiabendazole, Cyclophophamide, Chlorambucil, Cisplatin, Diloxanide Furoate, Trimethoprim, Mefloquine, Mafenide, Amantidine, Zidovudine, Stavudine, Lamivudine, Foscarnet, Ganciclovir, Acyclovir, Alprazolam,Triazolam, Diazepam, Buspirone, Promazine, Pargyline, Guanadrel, Terazosin, Dopamine, Dobutamine, Noradrenaline, Atenolon, Pralidoxime, Isoprenaline, Pyridostigmine, Tacrine, Papaverine, Naloxone, Naltrexone, Morphine, Triamterene, Amiloride, Diltiazem, Verapamil, Nifedipine, Amlodipine, Atropine, D-Tubocurarine, Succinyl Choline, Emetine, Hydralazine, Reserpine, Vit. E, Tocopherols, Vit. A, Spiranolactone, Caffeine, Codeine, Piperacillin, Ticarcillin, Idoxiuridine, Fluorouracil, Metformin, Rosiglitazone, Glipizide, Gliburide, Busulfan, Mercaptopurine, Melphalan,Methyl Dopa, Minoxidil, Sulindac, Flucortisone, Ciprofloxacin, Gatifloxacin,Tamoxifen, Tolbutamide, Bupivacaine, Clomiphene, Diethyl Carbamazepine, Undecylenic Acid,Flucytosine, Griseofulvin, Terbinafine, Tolnaftate, Miconazole, Itraconazole, Lomefloxacin,Piperazine, Ivermectin,Kanamycin,Gentamicin,Minocycline, Rolicycline,

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Clindamycin,Vancomycin,Colistin,Polymixin, Bacitracin, Gramicidin, Mechlorethamine, Ifosfamide, Procarbazine,, Carboplatin, Hydroxyurea,Ketamine,Propofol, Halothane,Primidone, Gabapentin,

Theophylline, Theobromine, Amphetamine, Sibutramine, Buproprion,Phenylephrine, Tolazoline, Phentolamine, Donepezil, Edrophonium,Torasemide, Nitroglycerin, Digoxin,Enalapril,Losartan,

Valsartan,Clofibrate, Gemfibrozil,Fenofibrate, Nicotinic Acid, Probucol, Warfarin, Glimepiride, Propyl Thiouracil, Methimazole, Clemastine, Loratidine, Famotidine, Progesterone, Structure Of All Vitamins, Atovastatin(LIPITOR), Simvastatin.

STARTING MATERIAL OF FOLLOWING:

Dapsone,

isoniazid,

etahmbutol,

pyrizinamide,

chloroquine,

ampicilin,

chlorpromazine, ephedrine,

haloperidol, diazepam. Glutethimide,

phenobarbitone, nikethamide,

isoprenaline,

propranalol, neostigmeine, furosemide, hydrochlorthiazide, lignocaine, procaine, diphenhydramin, pethidine, indomethacin, phenylbutazone, thyroxine,acetozolamide, thiotepa, cloxacillin.nephazoline, digitoxin, atropine, cocaine, methotrexate, trimethoprim, clonidine, phentoin, papverine, quinine, mepyramine, promathazine,cyclizine, cetrizine, cyproheptadine, triprolidine, astemizole, cimetidine, ranitine, antazoline, benzocaine, ketamine, valproic acid, carbamazepine, methohexital, amitryptiline, testosterone, progesterone, hydrocortisone, diethylstilbesterol, dienesterol, ethacrynic acid, allopurinol, captopril, proparanalol, guanethidine, dextripropoxyphene. Ibuprofen, indomathacin, prednisolone, betamethasone, triamicinolone, cortisone, estradiol, cholesterol, stanozolol, chloramphenicol, , diloxanide furoate, trimethoprim, mefloquine, amantidine, diazepam, dopamine, dobutamine, 08401782004, 07814727760 Best Luck

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noradrenaline, atenolon, pralidoxime, isoprenaline, pyridostigmine, diltiazem, verapamil, nifedipine, amlodipine, atropine, d-tubocurarine, succinyl choline, emetine, hydralazine, clofibrate,

gemfibrozil,fenofibrate, nicotinic acid, sulindac, progesterone, edrophonium, nephazoline (these are enough)

-important SAR related point:

E:g position responsible for acid instability of erythromycin.

No of isomers for particular drug.

Active isomer.

Group responsible for activity of drug.

Which class drug belongs (chemical class, not pharmacological.pharmacological class from KDT only)

Steroid chapter is very important.

IUPAC you can see of above drugs from Harkishan singh book.just see the structure u will notice how iupac is given..for some of above drugs IUPAC must be complex and lengthy or not found just leave it.

Bioisosterism. QSAR from FOYE/SN Pandya. COMPFA like softwares.(NIPER) 08401782004, 07814727760 Best Luck

Pharmaosmosis.blogspot.com IUPAC From Harkishan Singh book only.

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PHARMACOGNOSY:

Kokate remains the standard book.

Whole book.

B.S, C.C, SYNONYM,USE,ADULTERANT,CHEMICAL TEST,SUBSTITUTE,STRUCTURE (OF IMP DRUGS)

IF THERE ARE LESS ADULTERANTS OR LESS INFO ABOUT ADULTERANTS IN KOKATE SEE TREASE AND EVANS FOR FURTHER.

EARLIER CHAPTERS GENERAL INTRODUCTION ARE IMPORTANYT FROM KOKATE. Trease-evans -see flavonoids and quality control chapter from it. And some tables from it. WHO guidelines Kokate is good but with limited information. see other book. Caretenoids Agrawal is good book. Remember only no of double bonds,structure,use. Biochemical pathways remember starting points. Amino acids from which alkaloids are derived are to be remembered

E:g tropane alkaloids from ornithine.

Microscopy of following drugs which seem important has to be done:khandelwaal

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Read Khandelwall book other then above microscopies full.

ORGANIC CHEMISTRY :

Read only name reactions:Hoffman rearrangement etc (Mehta and Mehta or Morrison/Boyd- We will provide in postal series. Stereochemistry from (M/M or M/B). Various catalyst from (M/M)

E:g Lindlar catalyst,Wilkinson catalyst

General concepts from M/M Glossary of M/M.

INORGANIC CHEMISTRY:

Bahl and Tuli only thermodynamic and nuclear pharmacy chapters are very important. Other chapters are also important. Chatwal remember only common names of compounda and their use and water for injection limits.

MICROBIOLOGY :

only Kokare (whole book) is enough. For microbiological tests see inamdar. 08401782004, 07814727760 Best Luck

Pharmaosmosis.blogspot.com Vaccines read from it and also IP. Something from TORTORA (for NIPER we will say later). Diagnostic tests.

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Use Cooper-Gun for Sterilization, methods of sterilization,see vaccines,injections and Labels (in appendices)

BIOCHEMISTRY :

Satyanarayan is enough:

Do chapters 1 to 7 and metabolism chapters.

Do all important tables.

Biochemical teats (from R.K. Goyal - available in Gujarat only others students should see Satyanarayan and Kale book) Fermentation causing microorganism from Inamdar.

PHARMA ANALYSIS:

Mass silverstein, kasture, ravishankar. NMR Ravishankar,kasture,kemp. (NIPER Pavia) UV,IR ravishankar, kasture, chatwal/YR Sharma.

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AAS/Flame photometry/Fluorimetry Ravishankar,kasture. Gravimetry/Redox/Acid-base/poalrimetry/polarography/conductometry/amperometry Ravishankar kasture.\ Calculations -Underwood. DSC/DTA/TGA Martin, Remington, Karl-fischer/Kjeldahl/Caurius/Dumas etc determination methods - Bahl and Bahl or any other book. Assays- Kasture or ravishankar. See analysis part from /Remington also. Circular Dichromism. Chromatography Ravishankar/Kasture. etc

JURISPUDENCE

GK Jani/ Kuchekar. Read important years. D and C act Schedules Form numbers Members Place of various institutes.

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NIPER ONLY

Biostatistics general concepts Management/Accountancy/Partnership: Use Gujarat board 11 or 12 standard books like accountancy, secretial practice etc or what is studied in NIPER. Noble prize winners recent. Pharma News recent General knowledge. Apptitude (maths) Recent approved USFDA DRUIGS (do only approved in MAY/JUNE/JULY upto NIPER exam date) Banks full forms and when they established. Pharmaceutical Full forms. Name and location of important institutes. Any other useful information which we say at last time. The things which are being studied in NIPER are also asked.

Most of this we will include in postal /series until you Read above things.

Dont Read for NIPER before GPAT.

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If you prepare above way no one can beat you in GPAT/NIPER.

BEST OF LUCK TO ALL.

Compiled by Top NIPER 50 Rankers .

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