A CME-CErtifiEd SupplEMEnt to And Clinical Neurology News Introduction .......................................................... 3 Epidemiology .......................................................

3 Diagnosis and Classification of Partial-Onset Seizures .................................... 4 Current Pharmacologic Management Strategies for Partial-Onset Seizures in Adolescence .................................................... 8 Role of Nonpharmacologic Strategies for Treatment-Resistant Partial-Onset Seizures ......................................10 Monitoring ..........................................................11 Investigational Therapies for Inadequately Controlled Partial-Onset Seizures ....................11 Epilepsy in Adolescence: Special Considerations .....................................13 Conclusions ........................................................17 Post-Test .............................................................20 Faculty Rinat Jonas, Course Director Assistant Professor Boston University School of Medicine Director, Pediatric Long-Term EEG Monitoring Division of Pediatric Neurology Boston Medical Center Boston, Massachusetts Carl W. Bazil, MD, PhD Caitlin Tynan Doyle Professor of Clinical Neurology Director, Epilepsy and Sleep Division Columbia University College of Physicians and Surgeons New York, New York James W. Wheless, MD Professor and Chief of Pediatric Neurology Le Bonheur Chair in Pediatric Neurology University of Tennessee Health Science Center Director, Neuroscience Institute and Le Bonheur Comprehensive Epilepsy Program Le Bonheur Children's Hospital Memphis, Tennessee Optimizing Treatment of Adolescents With Partial-Onset Seizures and Date of Original Release: February 2013 Expiration Date: February 2014 Course Code: CEE80512 Estimated Time to Complete Activity: 2.0 hours This educational activity is supported by an educational grant from Eisai Inc. Jointly sponsored by Model is for illustrative purposes only.