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Social Phobia
()








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)(Hippocrates 400 .
"





"

) ) Charles Darwin
)) physiology
social phobia
) )phobie des situations socials
( )
( ) social neurosis

) (Joseph Wolpe ( systematic
) desensitization


( ) Isaac Marks



" " (
Diagonstic and Statistical Manual of
Mental Disorders ),
1989


1985


) ) Michael Liebowitz
) ) Richard Heimberg
(DSM-
) IV ( social
) ) phobia ( social
anxiety disorder ),
) ) psychology ()


1990

:

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%90

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\
observational
) )learning .
( )

30 50
" "



( Bruch and Heimberg 1994:
) Caster et al 1999
( ) Daniel and Plomin 1985


.


%15-10

.
.


.



( )
(Stemberg et al 1995
)



Beidel
) and Turner 1998) ,

) )Gilmartin 1987



.






( ) Leung et al 1994

-




.

" "









"" ""


( )
( ) fight-or-flight





.




)(serotonin
) )dopamine neurotransmission D2



) ) Norepinephrine
) ) GABA


amygdada

) ) Anterior cingulated cortex

.


( )
( )




( schema ),





( safety
) behaviors ) ( clark & wells 1995



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) ) unipolar depression
14263 24
166


panic disorder 33
% generalized anxietr disorder
%19 post traumatic stress
disorder % 36 substance abuse
disorder % 18 .% 23



%75 %61 %90
) ) Avoidant personality disorder



(bipolar disorder ),

cyclothymic-anxious-sensitive!


hypomania
.


" "

%90




.






.








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(
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.



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.

B F Skinner

()

()



""




( )
(
)

2006
amygdala limbic system








:
( Cognitive-
) behavioral therapy CBT
.

) ) psychotherapy




:

:
















Heimberg


interpersonal therapy

.


SSRIs
( Selective serotonin
) reuptake inhibitors SSRI



paroxetine
paxil seroxat

1995
% 55
% 23.9
2004
fluoxetine


50.8 % 54.2
% 31.7 1 2
Clinical Global Impression-Improvement scale
,
.




2004








1985
( ) monoamine oxidase inhibitors MAOI
.





(
Reversible inhibitors of monoamine oxidase subtype A
) RIMA
.

alprzolam clonazepam






GABA

mirtazapine



performance phobia
beta blockers


d-cycloserine DCS



agonist NMDA


.

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