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Social Phobia
()
.
)(Hippocrates 400 .
"
"
) ) Charles Darwin
)) physiology
social phobia
) )phobie des situations socials
( )
( ) social neurosis
) (Joseph Wolpe ( systematic
) desensitization
( ) Isaac Marks
" " (
Diagonstic and Statistical Manual of
Mental Disorders ),
1989
1985
) ) Michael Liebowitz
) ) Richard Heimberg
(DSM-
) IV ( social
) ) phobia ( social
anxiety disorder ),
) ) psychology ()
1990
:
( 1426: )1
:
-%7
%14
2 1
..
% 13
.
-
..
.
- -
.. .
()
%0.9 %1.7 %1.5
%2.6 .
7
%14
2 1 .
.
%13 .
.
:
12 17
.
.
.
.
%80
: %45
%59 %19
.%17
.
.
%70
%63 .
.
.
.
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.
..
.
.
.
..
()
.. ..
.
..
..
..
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..
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.
!!..
:
. .
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%90
.
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-1 ( ) .
.
-2
.
-3
.
-4
.
-5
.
-6
.
-7
.
-8 .
-9
.
-10 .
\
observational
) )learning .
( )
30 50
" "
( Bruch and Heimberg 1994:
) Caster et al 1999
( ) Daniel and Plomin 1985
.
%15-10
.
.
.
( )
(Stemberg et al 1995
)
Beidel
) and Turner 1998) ,
) )Gilmartin 1987
.
( ) Leung et al 1994
-
.
" "
"" ""
( )
( ) fight-or-flight
.
)(serotonin
) )dopamine neurotransmission D2
) ) Norepinephrine
) ) GABA
amygdada
) ) Anterior cingulated cortex
.
( )
( )
( schema ),
( safety
) behaviors ) ( clark & wells 1995
.
-:
-1
.
.
-2
.
-3
.
-4 .
-5 18
.
-6
.
.
"
"
"
" .
.
.
) ) unipolar depression
14263 24
166
panic disorder 33
% generalized anxietr disorder
%19 post traumatic stress
disorder % 36 substance abuse
disorder % 18 .% 23
%75 %61 %90
) ) Avoidant personality disorder
(bipolar disorder ),
cyclothymic-anxious-sensitive!
hypomania
.
" "
%90
.
.
" .
" ( 1414 ) .
(
)
.
)..
.
.
.. .
.
B F Skinner
()
()
""
( )
(
)
2006
amygdala limbic system
:
( Cognitive-
) behavioral therapy CBT
.
) ) psychotherapy
:
:
Heimberg
interpersonal therapy
.
SSRIs
( Selective serotonin
) reuptake inhibitors SSRI
paroxetine
paxil seroxat
1995
% 55
% 23.9
2004
fluoxetine
50.8 % 54.2
% 31.7 1 2
Clinical Global Impression-Improvement scale
,
.
2004
1985
( ) monoamine oxidase inhibitors MAOI
.
(
Reversible inhibitors of monoamine oxidase subtype A
) RIMA
.
alprzolam clonazepam
GABA
mirtazapine
performance phobia
beta blockers
d-cycloserine DCS
agonist NMDA
.
)1
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)2 .
)3 .
...... .
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....
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)5
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)13
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