2013 Project Lead The Way,

Inc.
PBS Project 6.1.1 Student Response Sheet Page 1



Project 6.1.1: Student Response Sheet

Introduction
Anna Garcia was only 38 when she died, meaning that at least one of her body
systems was no longer able to support life. The failure of one or more of her body
systems may be the result of injury due to an accident or could be the result of an
illness or a combination of illnesses. Before we can determine which system or
systems failed or what caused the failure which led to her death, we have to learn
more about the human body.

The human body is an amazing machine composed of many interrelated systems
which are in turn composed of cells, tissues, and organs that act independently and
interdependently within the body. No individual component of a human body works
alone. Components of each system in the body affect or interact with every other
system. The body is dependent upon the many interactions between all systems and
structures to maintain homeostasis and health. In this activity you will investigate the
different body systems that make up the human body and explore all of the ways
Annas various illnesses affected each body system, potentially resulting in her
premature death.

Procedure:

1. Look back in your course file and list all of the ways each body system was
impacted by the illness or disease Anna Garcia experienced in her life.
2. Reference Autopsy Reports, Medical Histories and past lab activities to help you
organize this information.
3. Record any evidence that shows how the illness or disease may have been
involved with her untimely death.
4. Be specific about relationships between body systems and illness. You will use
this chart to help construct your final timeline that explains how Anna died.
5. You will need to eventually upload this document to your e-portfolio under Annas
Cause of Death.










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Inc.
PBS Project 6.1.1 Student Response Sheet Page 2





Part II: Annas Illnesses

Illnesses
Effect on
System (if
applicable)


Diabetes Sickle Cell
Anemia
Heart Disease Urinary Tract
Infection
Cardiovascular









This can
cause
hypertension
causing the
vessels to
constrict and
restrict blood
flow. The
complications
of diabetes
damages the
blood vessels.




















This can cause
clots in arteries
restricting
blood flow.
Increased
cardiac output
is necessary to
compensate
for reduced
oxygen levels.
Buildup of
cholesterol in
the arteries or
the vessels
hardening can
cause blood to
cease flowing.

Infection
happens when
a bacteria gets
into the
bladder. When
infected it does
filter as well.
Because of her
decrease in
blood flow she
is more
susceptible to
infection.
Digestive High blood Bilirubin Heart disease The bacteria E.



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Inc.
PBS Project 6.1.1 Student Response Sheet Page 3










sugar levels
can cause
damage to the
vagus nerve,
that controls
stomach
contractions.
This can
cause a
buildup of
stomach
content and
acid
destroying the
digestive
system.
gallstones -
sickle cells die
in 20 days;
liver breaks
down the
bilirubin; extra
bilirubin can
become a
gallstone in the
gallbladder


(bilirubin forms
bile)





can lead to a
buildup of fluid
in areas like
the liver and
the abdomen.
This leads to
damage of the
system and
could lead to
death.
coli (the most
common
bacteria that
infect the
urinary tract),
live in the
digestive
system.
Digestive
system helps
filter through
what bacteria
stay or leave
the body.
Immune









Type 1 is an
autoimmune
disorder
meaning the
body already
has a hard
time telling
which cells
are bad and
which are
good
The blockage
of blood
vessels does
not allow for
the transport of
germ-fighting
cells (like T
cells).
Increases
infection
happens.
Heart disease
may weaken
the immune
system by not
supplying the
body enough
oxygen to
create cells to
combat
infections
Increased
production of
lymphocytes
(B & T cells)
and antibodies
against the
bacteria;
Inflammatory
response (may
increase
additional UTI
and/or damage
to urinary tract
structures.
Nervous









Nerves are
damaged
when oxygen
cant get
where it needs
to go, this is a
problem
because of
hypertension.

Increased risk
of stroke,
which can
damage the
nervous
system.
Increased in
children.
When nerves
get deprived of
oxygen they
begin to die
but nerves in
the heart do
not repair.
Spinal injury
impairs the
bladder.
Nervous
disorder
causes loss of
bladder
control.



2013 Project Lead The Way,

Inc.
PBS Project 6.1.1 Student Response Sheet Page 4

Respiratory









When the
vessels are
blocked,
oxygen
doesnt get
where it is
needed
Acute chest
syndrome.
Blockage of
blood vessels
causing lack of
oxygen.
Processes like
cellular
respiration can
be affected.
When the
heart isnt
working
oxygen doesnt
get where its
needed or
enough and
cells begin to
die.


Waste
products from
the respiratory
system are not
cleaned/
filtered as well.
Some bacteria
might build up
and cause an
infection.
Urinary









A buildup of
ketones could
have corroded
her urinary
system. The
kidneys can
be damaged
from filtering
too much
blood from
high blood
sugar levels.
Tract
infections are
more likely to
occur because
of a sickle
crisis.
Blood pressure
problems that
cause heart
disease can
put strain on
the urinary
system and
damage it
More likely to
get infection if
you are
diabetic. May
lead to kidney
stones and
pain. Due to
lack of blood
flow.

Sources Used:
webmd.com
medicinenet.com