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Multiple Choice Questions
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Q.2- Choose the Dienoic fatty acid out of the followinga) Oleic acid
b) Linoleic acid
c) Linolenic acid
d) Stearic acid
Q.3- Which of the following lipids is abundantly present in the white matter of brain?
a) Galactocerebroside
b) Glucocerebroside
c) Triglycerides
d) Gangliosides
Q.4- Which out of the following is not a Glycerophospholipid?
a) Cardiolipin
b) Plasmalogen
c) Lecithin
d) Sphingomyelin
Q.5- Which out of the following enzymes is defective in Gauchers disease?
a) - Glucocerebrosidase
b) Hexosaminidase A
c) Sphingomyelinase
d) - Galactocerebosidase
Q.6- Choose the Glycerophospholipid that acts as a precursor for second messengera) Phosphatidyl choline
b) Phosphatidyl Inositol
c) Phosphatidyl Serine
d) Phosphatidyl Ethanolamine
Q.7- Cholesterol is transported from extra hepatic tissues to liver by which of the following
lipoproteins?
a) Chylomicrons
b) VLDL
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c) LDL
d) HDL
8) All are non-essential fatty acids excepta)Palmitic acid
b) Linolenic
c) Oleic acid
d) Stearic acid
9) Which out of the following fatty acids is a precursor of prostaglandins?
a) Linoleic acid
b) Arachidonic acid
c) Eicosapentaenoic acid
d) Linolenic acid
10) Which of the following is an animal sterol?
a)Ergo sterol,
b) Stigma sterol,
c) Sitosterol
d) Cholesterol
11) Which out of the following is a fatty acid with 16 carbon atoms and one double bond?
a) Palmitoleic acid
b) Stearic acid
c) Erucic acid
d) Elaidic acid
12) Which out of the following is an 6 fatty acid?
a) Linolenic acid
b) Elaidic acid
c) Oleic acid
d) Arachidonic acid
13) A polar derivative of cholesterol is
a) Bile salt
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b) Oestrogen
c) Vitamin D
d) Progesterone
14) Which type of lipid is a receptor for cholera toxin in the intestine?
a) GM2 Ganglioside
b) GM1Ganglioside
c) Sphingomyelin
d) Galactocerebroside
15) Acetyl number is a measure ofa) Degree of unsaturation of a fat
b) Degree of rancidity of a fat
c) Measure of volatile fatty acids in a fat
d) Measure of number of OH groups in a fat
16) All are conditions of hypercholesterolemia excepta) Anemia,
b) Diabetes Mellitus,
c) Hypothyroidism
d) Nephrotic syndrome
17) Which out of the following is an inter mediate both for the synthesis of phospholipids and
Triacylglycerols?
a) Diacyl glycerol
b) Cholesterol
c) Choline
d) Inositol
18) Which fatty acid would have the least melting point out of the following-?
a) Stearic acid
b) Arachidonic acid
c) Timnodonic acid
d) Palmitic acid
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19) A 3 year child was brought with hepatosplenomegaly and mental retardation. Biopsy reveals
accumulation of sphingomyelin. What is the nature of the disease?
a)Gauchers
b) Niemann Picks
c) Krabbes
d Tay Sachs
20) Which of the following is not a source of glycerol?
a) Diet
b) Adipolysis
c) Glycolysis
d) Glycogenolysis
Answer Key
1)- c, 2)-b, 3)-a, 4)-d, 5)-a, 6)-b, 7)-d, 8)-b, 9)-b,10)-d,11)-a,12)-d,13)-a,14)-b,15)-d,16)-a, 17)-a, 18)c, 19)-b, 20)-d.
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Q.9) For which out of the following compounds cholesterol serves as a precursor?
a) Bile pigments
b) Bile salts
c) Vitamin K
d) Triacyl glycerol
Q.10) Glycerol is required for the formation of all of the following compounds excepta) Glucose
b) Triacyl glycerol
c) Phospholipids
d) Glycolipids
Q.11) Which out of the following is a fatty acid with 18 carbon atoms and one double bond in
the trans configuration?
a) Palmitoleic acid
b) Oleic acid
c) Erucic acid
d) Elaidic acid
Q. 12) Which out of the following is a hydroxy fatty acid?
a) Linolenic acid
b) Linoleic acid
c) Palmitic acid
d) Cerebronic acid
Q. 13)Which of the following enzymes is present in the snake venom ?
a) Phospholipase A1
b) PhospholipaseA2
c) Phospholipase B
d) Phospholipase D
Q. 14) Which type of lipid is negatively charged at physiological pH?
a) GM2 Ganglioside
b) Glucocerebroside
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c) Sphingomyelin
d) Galactocerebroside
Q. 15) The Iodine number of Linolenic acid isa) 1
b) 6
c) 4
d) 3
Q. 16) Which of the following is not a derived lipid?
a) Arachidonic acid
b) Diacyl glycerol
c) HDL
d) Vitamin D
Q. 17) Which out of the following is not an essential fatty acid
a) Arachidic acid
b) Arachidonic acid
c) Linoleic acid
d) Linolenic acid
Q. 18) The number of mgms of KOH required to neutralize the free and combined fatty acids
in one gram of a given fat is calleda) Acid number
b) Polenske number
c) Saponification number
d) Iodine number
Q. 19) Choose out of the following, a fatty acid with 20 carbon atoms and four double bondsa) Timnodonic acid
b) Arachidonic acid
c) Clupanodonic acid
d) Nervonic acid
Q. 20) Glycerol is not present inhttp://www.namrata.co/category/chemistry-of-lipids-and-eicosanoids/multiple-choice-questions-chemistry-of-lipids-and-eicosanoids/
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a) Cerebrosides
b) Platelet activating factor
c) Lecithin
d) Plasmalogen
Answer key
1)-a, 2)-a, 3)-d, 4)-a, 5)- b, 6)- d, 7)- b, 8)- c, 9)- b, 10)- d, 11)- d, 12)- d, 13)- b, 14)- a, 15)- b, 16)c, 17)- a, 18)- c, 19)- b, 20)-a.
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c) Lecithin
d) Sphingomyelin
Q.5- Which out of the following enzymes is defective in Gauchers disease?
a) - Glucocerebrosidase
b) Hexosaminidase A
c) Sphingomyelinase
d) - Galactocerebosidase
Q.6- Choose the Glycerophospholipid that acts as a lipotropic agenta) Phosphatidyl choline
b) Phosphatidyl Inositol
c) Phosphatidyl Serine
d)Cardiolipin
Q.7- Dietary triacylglycerols are transported from intestine to hepatic and extra hepatic tissues
by which of the following lipoproteins?
a) Chylomicrons
b) VLDL
c) LDL
d) HDL
Q.8) All are non -essential fatty acids excepta)Oleic acid
b) Linolenic
c) Palmitic acid
d) Stearic acid
Q.9) For which out of the following compounds cholesterol does not serve as a precursor?
a) Bile pigments
b) Bile salts
c) Vitamin D
d) Sex hormones
Q.10) Glycerol is required for the formation of all of the following compounds excepthttp://www.namrata.co/category/chemistry-of-lipids-and-eicosanoids/multiple-choice-questions-chemistry-of-lipids-and-eicosanoids/
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a) Glucose
b) Triacyl glycerol
c) Phospholipids
d) Glycolipids
Q.11) Which out of the following is a fatty acid with 18 carbon atoms and one double bond in
the cis configuration?
a) Palmitoleic acid
b) Oleic acid
c) Erucic acid
d) Elaidic acid
Q. 12) Which out of the following is an 6 fatty acid?
a) Linolenic acid
b) Linoleic acid
c) Palmitic acid
d) Cerebronic acid
Q. 13) The normal level of serum Total cholesterol is?
a) 150-220 mg/dl
b) 100-200 mg/dl
c) 1.5-2.5g/dl
d) 20-40 mg/dl
Q. 14) Which type of lipid is left undegraded in Niemann Picks disease?
a) GM2 Ganglioside
b) GM1Ganglioside
c) Sphingomyelin
d) Galactocerebroside
Q. 15) The Iodine number of cholesterol isa) 1
b) 2
c) 4
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d) 3
Q. 16) What are the components of a Galactocerebroside?
a) Sphingosine+ fatty acid+ Galactose
b) Glycerol +Fatty acids +Phosphoric acid+ Galactose
c) Glycerol +Fatty acids +Phosphoric acid +Nitrogenous base+ Galactose
d) Sphingosine+ fatty acids +Phosphoric acid+ Galactose
Q. 17) Which phospholipid out of the following is a component of inner mitochondrial
membrane?
a) Cardiolipin
b) Lecithin
c) Plasmalogen
d) Cephalin
Q. 18)- The significance of estimating L: S ratio of amniotic fluid in a pregnant female lies in
evaluatinga) Fetal heart rate
b) Fetal lung maturity
c) Fetal head size
d) Expected date of delivery
Q. 19) Choose out of the following, a fatty acid with 20 carbon atoms and four double bondsa) Timnodonic acid
b) Arachidonic acid
c) Clupanodonic acid
d) Nervonic acid
Q. 20) Glycerol is present ina) Cerebrosides
b) Gangliosides
c) Sphingomyelin
d) Plasmalogen
Key to Answers
1)- c, 2)-a,3)-b,4)-d,5)-a,6)-a,7)-a,8)-b,9)-a,10)-d,11)-b,12)-b,13)-b,14)-c,15)-b,16)-a,17)-a,18)http://www.namrata.co/category/chemistry-of-lipids-and-eicosanoids/multiple-choice-questions-chemistry-of-lipids-and-eicosanoids/
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b,19)-b,20)-d
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d) Linolenic acid
Q.9- What is the cause of hyper acidity on long-term usage of Aspirin?
a) Inhibition of cyclo oxygenase
b) Increased synthesis of PGs
c) Inhibition of Phospholipase A2
d) All of the above
Q.10- Which nitrogenous base out of the following is present in lecithin ?
a) Choline
b) Adenine
c) Ethanolamine
d) Any of the above
Q.11- Cholesterol is a precursor of all excepta)Bile salts,
b)Bilirubin
c) Steroids
d) vitamin D
Q.12- Glycerol is used for the synthesis of all excepta) Glucose.,
b) Phospholipids,
c) Glycolipids,
d) Triacylglycerol
Q.13- Which out of the following is a fatty acid with 16 carbon atoms and one double bond?
a) Palmitoleic acid
b) Oleic acid
c) Erucic acid
d) Elaidic acid
Q.14-Which out of the following is an 3 fatty acid?
a) Linolenic acid
b) Linoleic acid
c) Palmitic acid
d) Arachidonic acid
Q.15- Fats on keeping fora long time under go spontaneous hydrolysis, what is this process
called?
a) Saponification
b) Hydrolytic Rancidity
c) Decomposition
d) All of the above
Q.16- Which out of the following enzymes is deficient in Gauchers disease?
a) Beta Glucosidase
b) Beta Galactosidase
c) Hexosaminidase A
d) Neuraminidase
Q.17- Prostcyclins are synthesized in- ?
a) Platelets
b) Endothelial cells
c) Gastric mucosa
d) Basophils
Q.18- Cyclo-oxygenase is inhibited by all except?
a) Aspirin
b) Indomethacin
c) Brufen
d) Zileuton
Q.19- The normal level of serum Total cholesterol is?
a) 150-220 mg/dl
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b) 100-200 mg/dl
c) 1.5-2.5g/dl
d) 20-40 mg/dl
Q.20- Choose out of the followings, a fatty acid with 20 carbon atoms and five double bondsa) Timnodonic acid
b) Arachidonic acid
c) Clupanodonic acid
d) Nervonic acid
Q.21- Which type of lipid is a receptor for cholera toxin in the intestine?
a) GM2 Ganglioside
b) GM1 Ganglioside
c) Sphingomyelin
d) Galactocerebroside
Q.22- The significance of estimating L: S ratio of amniotic fluid in a pregnant female lies in
evaluatinga) Fetal heart rate
b) Fetal lung maturity
c) Fetal head size
d) Expected date of delivery
Q.23- Iodine number is a measure ofa) Degree of unsaturation of a fat
b) Degree of rancidity of a fat
c) Measure of volatile fatty acids in a fat
d) Measure of number of OH groups in a fat
Q.24-Which phospholipid out of the following is antigenic in nature -?
a) Cardiolipin
b) Lecithin
c) Plasmalogen
d) Cephalin
Q.25- Which out of the followings is not a derived lipid?
a) Ketone body
b) PGE2
c) Diacylglycerol,
d) Galactosyl ceramide
Q.26- What are the components of a ceramide?
a) Sphingosine+ fatty acid
b) Glycerol+Fatty acids+Phosphoric acid
c) Glycerol+Fatty acids+Phosphoric acid+Nitrogenous base
d) Sphingosine+ fatty acids+Phosphoric acid
Q.27- Choose the incorrect statementa) The chemical name of Arachidonic acid is Eicosa penta enoic acid
b) Cyclo-oxygenase and peroxidase are the components of PG-H synthase complex
c) Oleic acid is represented by 18;1,9
d) NSAIDs act by inhibiting Phospholipase A2 enzyme.
Answers1-(b)- VLDL
2-(b)- Palmitic acid
3-(d)- Plasmalogen
4-(d) All of the above
5-(d) Stearic acid
6-(c) Phospholipid
7-(c) Arachidonic acid
8-(a) Linoleic acid
9-(a)- Inhibition of cyclo-oxygenase enzyme
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10-(a) Choline
11-(b) Bilirubin
12-(c) Glycolipids
13-(a) Palmitoleic acid
14-(a)-- Linolenic acid
15-(b)-Hydrolytic Rancidity
16-(a) Beta Glucosidase
17-(b)-Endothelial cells
18-(d)-Zileuton
19-(a) 150-220 mg/dL
20-(a) Timnodonic acid
21-(b) GM1- Ganglioside
22-(b) Fetal lung maturity
23-(a)- Degree of unsaturation
24-(a)- Cardiolipin
25-(a)- Galactosyl Ceramide
26-(a)- Sphingosine+Fatty acid
27-(d) NSAIDs act by inhibiting Phospholipase A2 enzyme
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