Professional Documents
Culture Documents
By: Adrienne Gebele, Claire Phillips, Hayley Aanestad, and Grace Delehanty
Flaxseed
By: Adrienne Gebele, Claire Phillips, Hayley Aanestad, and Grace Delehanty
What is flax?
Linum usitatissimum
Flax is a member of the genus
Linum in the family Linaceae. It is a
food and fiber crop that is grown in
cooler regions of the world.
(Ehrlich, 2013)
UPERFOODS
low caloRic couNt
NutRitioNally-DeNse
BeNeficial to oNes health
Role PlaYeR iN disease pRevention
NatuRal-MaN CaNT MaKe This ONe!
OtheRs: Kale, SaLMoN, BlueBeRRies
FUNCTIONAL FOOD
Defined by American Dietetics Association as:
a food that provides additional health benefits that may reduce disease risk
and/or promote good health
What makes a food a functional food:
USES
Edible Oil:
- Bakery Items
- Cooking Oil
- Margarine
Functional Food:
- Cancer
Fiber:
- Blankets
- Carpets
- Mattress
- Towel
Industrial Products:
- Heart Disease
- Linoleum
- Varnish
- Menopause
- Paint
COMPONENTS
From Seed Pressing
Insoluble Fiber
Omega 3
Soluble Fiber
Lignans
Chemical compounds from plants
Precursor to Phytoestrogen
estrogen-like chemical
Antioxidant Capabilities
PURE SEED
PURE MEAL
(Honeyville, 2013)
Atherosclerosis
Cardiovascular Disease
Schizophrenia
Depression
Alzheimers
ADHD
Postmenopausal
Cancers
breast cancer
prostate cancer
Inflammatory
Interactions
1. Cardiovascular
Relativity
Cardiovascular Disease
May lead to: heart attack, heart failure, sudden death, stroke, and cardiac
rhythm issues.
(High Cholesterol)
Nine clinical trials suggest that 15-50 grams per day of whole flaxseed can reduce
total cholesterol and LDL up to 18%
(Bloedon, Szapary, 2004)
Effected by
-vasoconstriction
-glucose levels
-blood volume
Effects of Flax
-ALA is a natural
anti-inflammatory agent
therefore reducing
vasoconstriction
-Soluble fiber lowers glucose
levels by forming a gel which
delays postprandial glucose
absorption in the gut
-Lowers blood pressure
Atherosclerosis
The accumulation of fat, cholesterol,
and other substances forming tough
plaques on arterial walls, causing
them to harden.
Blood flow is limited and can cause
tissue death and blockage can lead
to stroke and heart attacks.
High cholesterol speeds up this
process, increasing risk
(A.D.A.M. Medical Encyclopedia, 2012)
Flax is a functional food that has gained attention in the area of Atherosclerotic
Cardiovascular Disease (ASCVD).
Research shows that various components have an overall antioxidant, antiinflammatory, antiplatelet, hypoglycemic, and BP lowering capabilities.
The Study
2. Obesity &
Diabetes
Obesity
(Campbell, 2012)
4. Diseases Associated
with the Brain
10-20% of the fatty acids in the brain is DHA, followed by <1% ALA and
EPA
Within the tissues, DHA accumulates to form the axons, synapses, and
myelin sheaths that allow brain function.
There is significant correlation between DHA supplementation brain
development.
Studies have found that infants fed formulas without DHA exhibit several
neurological and neurocognitive soft signs
Schizophrenia
-High EPA treatment in concordance with anti
schizophrenia medications show significant
improvements
-One study targeted newly diagnosed patients.
After a 12 week period more than 40% of the
patients treated with EPA required no other
treatment.
-Preterm infants are very susceptible
Mood Disorders
-Patients with depression treated with 1 g/day of
EPA showed improvement. The patients treated
with EPA reported an improvement of 56%.
(Peet & Stokes, 2005)
5. Postmenopausal
Lignans
-Menopause is characterized by the cessation of the menstrual cycle.
-Change in hormones: drop in estrogen
-Phytoestrogens- produced from lignans in the gut.
-Compete with xenoestrogens.
-Constant intake-comparable to xenoestrogens
very rapid rate of degradation
(Mayo, 1997)
Postmenopausal Symptoms
flax is a source of phytoestrogens
estrogen of plants
mimics normal natural estrogen in the body
thousand times weaker than human made estrogen
can bind in place of estrogen to reduce physical symptoms
prevents xenoestrogens from damaging healthy tissues
(Schardt, 2000)
6. Cancers
Breast cancer
-some studies suggest:
may decrease risk
demonstrates antiproliferative effects in breast tissue of women
protect against primary breast cancer
may decrease mortality rate of those living with breast cancer
-others studies suggest:
phytoestrogen causes an increase in risk of breast cancer
Prostate cancer
7. Inflammatory
Arthritis
- Arthritis is the inflammation of the joints
ALA:
LA:
-medications
include ibuprofen,
aspirin, & naproxen
-The inflammation
mechanism of the
body is a natural
response to injury
to stabilize and
inhibit movement
(Yoder, 2013)
Crete &
Southern Italy
Mediterranean vs Western
Total Energy Contributed By The Major Food Groups
(Nelstle, 2013)
Interactions
Pregnant women
Elder people
Diverticulitis
Swallowing or eating difficulties
Chronic constipation
Issues with gums, dentures, or dental
Hemophiliacs
Sources:
A.D.A.M. Medical Encyclopedia. (June 3, 2012). Hardening of Arteries. PubMed Health. Retrieved from: http://www.ncbi.nlm.nih.
gov/pubmedhealth/PMH0001224/.
Adlercreutz, H. (1995). Phytoestrogen: Epidemiology and a Possible Role in Cancer Protection. Environmental Health Perspectives. 103(Supp 7): 103112.
American Dietetics Association. (2013). Retrieved from: http://www.diabetes.org/diabetes-basics/type-2/.
Bhathena, S. & Velasquez, M. (November 17, 2013). Beneficial Role of Dietary Phytoestrogen in Obesity and Diabetes. The American Journal of Clinical
Nutrition. Retrieved From: http://ajcn.nutrition.org/content/76/6/1191.full.pdf+htm.
Bloedon, L. T., M. S., R. D., & Szapary, P. O., M. D. (2004). Flaxseed and Cardiovascular Risk. Nutrition Reviews, 62(1), 18-27.
Brooks, G. (2011). Mediterranean Diet- Summary & Chart. Patient.co.uk. Retrieved from: http://www.patient.co.uk/health/mediterranean-diet-summarychart#.\
Campbell SC, Bello NT. (2012). Omega-3 Fatty Acids and Obesity. J Food Nutr Disor 1:2. doi:10.4172/2324-9323.1000e105
Denny, S., MS, RDN (Ed.). (2013, April). What are functional foods? EatRight. Retrieved
from: http://www.eatright.org/Public/content.aspx?id=6442472528
Dupasquier, C., & Pierce, G. (2007). The cardiovascular benefits of consuming flaxseed: possible modes of action. Retrieved from http://www.flaxcouncil.
ca/english/pdf/Dupasquier & Pierce IAS review.pdf
Ehrlich, S. (2013, January 13). Flaxseed. Retrieved from http://umm.edu/health/medical/altmed/herb/flaxseed
Flaxseed. (nd). NYU Langone Medical Center, Retrieved from http://www.med.nyu.edu/content?ChunkIID=21714
Flax. (n.d.). Retrieved from http://www.unm.edu/~jessicam/219/2_definition_jessica.pdf
Sources Continue:
Fitzpatrick, K. (n.d.). Flax Fights Prostate Cancer. SaskFlax. Retrieved from: http://www.saskflax.com/article_flaxprostate.html
Hasler, C. (December 1, 2002). Functional Foods: Benefits, Concerns and Challenges-A Position Paper from the American Council on Science
and Health. The Journal of Nutrition, 132(12), 3772-3781. Retrieved from:http://jn.nutrition.org/content/132/12/3772.full.
Hendrich, S. (March 17, 2010). Iowa state nwrc study finds flaxseed lowers high cholesterol in men. Retrieved from http://archive.news.iastate.
edu/news/2010/mar/flaxseed.
Honeyville. (2013). Honeyville Food Products Inc. Retreived from:
http://store.honeyvillegrain.com/wholeflaxseeds50lb.aspx#.UnnHPzm5LHM
Indiana Hemophilia and Thrombosis Center. (2013). Clotting Disorders FAQs. Indiana Hemophilia and Thrombosis Center. Retrieved from:
http://www.ihtc.org/patient/blood-disorders/clotting-disorders/thrombosis-faqs/
Jhala, A., & Hall, L. (2010). Flax (linum usitatissimum l.): Current uses and future applications. AJBAS, Retrieved from http://www.ajbasweb.
com/ajbas/2010/4304-4312.pdf
Lipid profile. In (2012). Lab Tests Online. American Association for Clinical Chemistry. Retrieved from http://labtestsonline.
org/understanding/analytes/lipid/tab/glance.
Mayo, J. L., MD, FACOG. (1997). A natural approach to menopause. Applied Nutritional Science Reports, 5(7), 1-8.
Mcintosh, M. & Miller, C. (2001). A Diet Containing Food Rich in Soluble and Insoluble Fiber Improves Glycemic Control and Reduces
Hyperlipidemia Among Patients with Type 2 Diabetes Mellitus. Nutrition Review, 59(2), 52-55. DOI: 10.1111/j.1753-4887.2001.tb06976.
x. Retrieved From: http://onlinelibrary.wiley.com/doi/10.1111/j.1753-4887.2001.tb06976.x/abstract.
McNamara, R. & Carlson S.E. (2006). Role of omega-3 fatty acids in brain development and function: Potential implications for the
pathogenesis and prevention of psychopathology. ScienceDirect. Retrieved from: www.sciencedirect.com
Sources Continue:
Nelstle, M. (2013). Mediterranean Diets: historical and research overview. The American Journal of Clinical Nutrition. Retrieved
from: http://ajcn.nutrition.org/content/61/6/1313S.full.pdf.
No Author. (2013). Benefits of Flaxseed 11 Important and Healthy Benefit of Flaxseed. Benefit of Flaxseed. Retrieved from:
http://benefitofflaxseed.org/.
Parker, G. (2012). Omega-3 fatty acids and mood disorders. Drugs, 65(8), 1051-1059. Retreived from: http://link.springer.
com/article/10.2165/00003495-200565080-00002.
Peet M. & Stokes C. (June, 2005). Omega-3 Fatty Acids in the Treatment of Psychiatric Disorders. SpringerLink. 65(8) pp 10511059. Retrieved from: http://link.springer.com/article/10.2165/00003495-200565080-00002
Prasad, K. (1997). Dietary flax seed in prevention of hypercholesterolemic atherosclerosis.Atherosclerosis, 132(1), 69-76.
Retrieved from http://www.sciencedirect.com/science/article/pii/S0021915097061108
Prasad, K. (2007). A study on regression of hypercholesterolemic atherosclerosis in rabbits by flax lignan complex. JCPT, 12(4),
Retrieved from http://cpt.sagepub.com/content/12/4/304.short
Schardt, D. (Jan/Feb 2000). Phytoestrogens for Menopause. Nutrition Action Health Letter. Retrieved from: http://www.cspinet.
org/nah/soy/phytoestrogen.html
Simon, J. A., Chen, Y. H., & Bent, S. (2009). The relation of -linolenic acid to the risk of prostate cancer: a systematic review and
meta-analysis. The American journal of clinical nutrition, 89(5), 1558S-1564S The relation of -linolenic acid to the risk of
prostate cancer: a systematic review and meta-analysis. The American journal of clinical nutrition, 89(5), 1558S-1564S
University of Maryland Medical Center. (n.d.). Flax. University of Maryland Medical Center. Retrieved from http://www.unm.
Sources Continue:
University of Maryland Medical Center. (May 31, 2013). Possible Interactions with: Flaxseed. University of Maryland Medical
Center. Retrieved from: http://umm.edu/health/medical/altmed/supplement-interaction/possible-interactions-with-flaxseedoil
Yoder, J. (2013). Lipids Chapter 5: Function, Structure, Digestion, Transport Metabolism [PowerPoint slides]. Retireved from:
https://blackboard.ohio.edu/webapps/portal/frameset.jsp?tab_tab_group_id=_2_1&url=%2Fwebapps%2Fblackboard%
2Fexecute%2Flauncher%3Ftype%3DCourse%26id%3D_294775_1%26url%3D.
What is flax?
Linum usitatissimum
Flax is a member of the genus
Linum in the family Linaceae. It is a
food and fiber crop that is grown in
cooler regions of the world.
(Ehrlich, 2013)
UPERFOODS
low caloRic couNt
NutRitioNally-DeNse
BeNeficial to oNes health
Role PlaYeR iN disease pRevention
NatuRal-MaN CaNT MaKe This ONe!
OtheRs: Kale, SaLMoN, BlueBeRRies
FUNCTIONAL FOOD
Defined by American Dietetics Association as:
a food that provides additional health benefits that may reduce disease risk
and/or promote good health
What makes a food a functional food:
USES
Edible Oil:
- Bakery Items
- Cooking Oil
- Margarine
Functional Food:
- Cancer
Fiber:
- Blankets
- Carpets
- Mattress
- Towel
Industrial Products:
- Heart Disease
- Linoleum
- Varnish
- Menopause
- Paint
COMPONENTS
From Seed Pressing
Insoluble Fiber
Omega 3
Soluble Fiber
Lignans
Chemical compounds from plants
Precursor to Phytoestrogen
estrogen-like chemical
Antioxidant Capabilities
PURE SEED
PURE MEAL
(Honeyville, 2013)
Atherosclerosis
Cardiovascular Disease
Schizophrenia
Depression
Alzheimers
ADHD
Postmenopausal
Cancers
breast cancer
prostate cancer
Inflammatory
Interactions
1. Cardiovascular
Relativity
Cardiovascular Disease
May lead to: heart attack, heart failure, sudden death, stroke, and cardiac
rhythm issues.
(High Cholesterol)
Nine clinical trials suggest that 15-50 grams per day of whole flaxseed can reduce
total cholesterol and LDL up to 18%
(Bloedon, Szapary, 2004)
Effected by
-vasoconstriction
-glucose levels
-blood volume
Effects of Flax
-ALA is a natural
anti-inflammatory agent
therefore reducing
vasoconstriction
-Soluble fiber lowers glucose
levels by forming a gel which
delays postprandial glucose
absorption in the gut
-Lowers blood pressure
Atherosclerosis
The accumulation of fat, cholesterol,
and other substances forming tough
plaques on arterial walls, causing
them to harden.
Blood flow is limited and can cause
tissue death and blockage can lead
to stroke and heart attacks.
High cholesterol speeds up this
process, increasing risk
(A.D.A.M. Medical Encyclopedia, 2012)
Flax is a functional food that has gained attention in the area of Atherosclerotic
Cardiovascular Disease (ASCVD).
Research shows that various components have an overall antioxidant, antiinflammatory, antiplatelet, hypoglycemic, and BP lowering capabilities.
The Study
2. Obesity &
Diabetes
Obesity
(Campbell, 2012)
4. Diseases Associated
with the Brain
10-20% of the fatty acids in the brain is DHA, followed by <1% ALA and
EPA
Within the tissues, DHA accumulates to form the axons, synapses, and
myelin sheaths that allow brain function.
There is significant correlation between DHA supplementation brain
development.
Studies have found that infants fed formulas without DHA exhibit several
neurological and neurocognitive soft signs
Schizophrenia
-High EPA treatment in concordance with anti
schizophrenia medications show significant
improvements
-One study targeted newly diagnosed patients.
After a 12 week period more than 40% of the
patients treated with EPA required no other
treatment.
-Preterm infants are very susceptible
Mood Disorders
-Patients with depression treated with 1 g/day of
EPA showed improvement. The patients treated
with EPA reported an improvement of 56%.
(Peet & Stokes, 2005)
5. Postmenopausal
Lignans
-Menopause is characterized by the cessation of the menstrual cycle.
-Change in hormones: drop in estrogen
-Phytoestrogens- produced from lignans in the gut.
-Compete with xenoestrogens.
-Constant intake-comparable to xenoestrogens
very rapid rate of degradation
(Mayo, 1997)
Postmenopausal Symptoms
flax is a source of phytoestrogens
estrogen of plants
mimics normal natural estrogen in the body
thousand times weaker than human made estrogen
can bind in place of estrogen to reduce physical symptoms
prevents xenoestrogens from damaging healthy tissues
(Schardt, 2000)
6. Cancers
Breast cancer
-some studies suggest:
may decrease risk
demonstrates antiproliferative effects in breast tissue of women
protect against primary breast cancer
may decrease mortality rate of those living with breast cancer
-others studies suggest:
phytoestrogen causes an increase in risk of breast cancer
Prostate cancer
7. Inflammatory
Arthritis
- Arthritis is the inflammation of the joints
ALA:
LA:
-medications
include ibuprofen,
aspirin, & naproxen
-The inflammation
mechanism of the
body is a natural
response to injury
to stabilize and
inhibit movement
(Yoder, 2013)
Crete &
Southern Italy
Mediterranean vs Western
Total Energy Contributed By The Major Food Groups
(Nelstle, 2013)
Interactions
Pregnant women
Elder people
Diverticulitis
Swallowing or eating difficulties
Chronic constipation
Issues with gums, dentures, or dental
Hemophiliacs
Sources:
A.D.A.M. Medical Encyclopedia. (June 3, 2012). Hardening of Arteries. PubMed Health. Retrieved from: http://www.ncbi.nlm.nih.
gov/pubmedhealth/PMH0001224/.
Adlercreutz, H. (1995). Phytoestrogen: Epidemiology and a Possible Role in Cancer Protection. Environmental Health Perspectives. 103(Supp 7): 103112.
American Dietetics Association. (2013). Retrieved from: http://www.diabetes.org/diabetes-basics/type-2/.
Bhathena, S. & Velasquez, M. (November 17, 2013). Beneficial Role of Dietary Phytoestrogen in Obesity and Diabetes. The American Journal of Clinical
Nutrition. Retrieved From: http://ajcn.nutrition.org/content/76/6/1191.full.pdf+htm.
Bloedon, L. T., M. S., R. D., & Szapary, P. O., M. D. (2004). Flaxseed and Cardiovascular Risk. Nutrition Reviews, 62(1), 18-27.
Brooks, G. (2011). Mediterranean Diet- Summary & Chart. Patient.co.uk. Retrieved from: http://www.patient.co.uk/health/mediterranean-diet-summarychart#.\
Campbell SC, Bello NT. (2012). Omega-3 Fatty Acids and Obesity. J Food Nutr Disor 1:2. doi:10.4172/2324-9323.1000e105
Denny, S., MS, RDN (Ed.). (2013, April). What are functional foods? EatRight. Retrieved
from: http://www.eatright.org/Public/content.aspx?id=6442472528
Dupasquier, C., & Pierce, G. (2007). The cardiovascular benefits of consuming flaxseed: possible modes of action. Retrieved from http://www.flaxcouncil.
ca/english/pdf/Dupasquier & Pierce IAS review.pdf
Ehrlich, S. (2013, January 13). Flaxseed. Retrieved from http://umm.edu/health/medical/altmed/herb/flaxseed
Flaxseed. (nd). NYU Langone Medical Center, Retrieved from http://www.med.nyu.edu/content?ChunkIID=21714
Flax. (n.d.). Retrieved from http://www.unm.edu/~jessicam/219/2_definition_jessica.pdf
Sources Continue:
Fitzpatrick, K. (n.d.). Flax Fights Prostate Cancer. SaskFlax. Retrieved from: http://www.saskflax.com/article_flaxprostate.html
Hasler, C. (December 1, 2002). Functional Foods: Benefits, Concerns and Challenges-A Position Paper from the American Council on Science
and Health. The Journal of Nutrition, 132(12), 3772-3781. Retrieved from:http://jn.nutrition.org/content/132/12/3772.full.
Hendrich, S. (March 17, 2010). Iowa state nwrc study finds flaxseed lowers high cholesterol in men. Retrieved from http://archive.news.iastate.
edu/news/2010/mar/flaxseed.
Honeyville. (2013). Honeyville Food Products Inc. Retreived from:
http://store.honeyvillegrain.com/wholeflaxseeds50lb.aspx#.UnnHPzm5LHM
Indiana Hemophilia and Thrombosis Center. (2013). Clotting Disorders FAQs. Indiana Hemophilia and Thrombosis Center. Retrieved from:
http://www.ihtc.org/patient/blood-disorders/clotting-disorders/thrombosis-faqs/
Jhala, A., & Hall, L. (2010). Flax (linum usitatissimum l.): Current uses and future applications. AJBAS, Retrieved from http://www.ajbasweb.
com/ajbas/2010/4304-4312.pdf
Lipid profile. In (2012). Lab Tests Online. American Association for Clinical Chemistry. Retrieved from http://labtestsonline.
org/understanding/analytes/lipid/tab/glance.
Mayo, J. L., MD, FACOG. (1997). A natural approach to menopause. Applied Nutritional Science Reports, 5(7), 1-8.
Mcintosh, M. & Miller, C. (2001). A Diet Containing Food Rich in Soluble and Insoluble Fiber Improves Glycemic Control and Reduces
Hyperlipidemia Among Patients with Type 2 Diabetes Mellitus. Nutrition Review, 59(2), 52-55. DOI: 10.1111/j.1753-4887.2001.tb06976.
x. Retrieved From: http://onlinelibrary.wiley.com/doi/10.1111/j.1753-4887.2001.tb06976.x/abstract.
McNamara, R. & Carlson S.E. (2006). Role of omega-3 fatty acids in brain development and function: Potential implications for the
pathogenesis and prevention of psychopathology. ScienceDirect. Retrieved from: www.sciencedirect.com
Sources Continue:
Nelstle, M. (2013). Mediterranean Diets: historical and research overview. The American Journal of Clinical Nutrition. Retrieved
from: http://ajcn.nutrition.org/content/61/6/1313S.full.pdf.
No Author. (2013). Benefits of Flaxseed 11 Important and Healthy Benefit of Flaxseed. Benefit of Flaxseed. Retrieved from:
http://benefitofflaxseed.org/.
Parker, G. (2012). Omega-3 fatty acids and mood disorders. Drugs, 65(8), 1051-1059. Retreived from: http://link.springer.
com/article/10.2165/00003495-200565080-00002.
Peet M. & Stokes C. (June, 2005). Omega-3 Fatty Acids in the Treatment of Psychiatric Disorders. SpringerLink. 65(8) pp 10511059. Retrieved from: http://link.springer.com/article/10.2165/00003495-200565080-00002
Prasad, K. (1997). Dietary flax seed in prevention of hypercholesterolemic atherosclerosis.Atherosclerosis, 132(1), 69-76.
Retrieved from http://www.sciencedirect.com/science/article/pii/S0021915097061108
Prasad, K. (2007). A study on regression of hypercholesterolemic atherosclerosis in rabbits by flax lignan complex. JCPT, 12(4),
Retrieved from http://cpt.sagepub.com/content/12/4/304.short
Schardt, D. (Jan/Feb 2000). Phytoestrogens for Menopause. Nutrition Action Health Letter. Retrieved from: http://www.cspinet.
org/nah/soy/phytoestrogen.html
Simon, J. A., Chen, Y. H., & Bent, S. (2009). The relation of -linolenic acid to the risk of prostate cancer: a systematic review and
meta-analysis. The American journal of clinical nutrition, 89(5), 1558S-1564S The relation of -linolenic acid to the risk of
prostate cancer: a systematic review and meta-analysis. The American journal of clinical nutrition, 89(5), 1558S-1564S
University of Maryland Medical Center. (n.d.). Flax. University of Maryland Medical Center. Retrieved from http://www.unm.
Sources Continue:
University of Maryland Medical Center. (May 31, 2013). Possible Interactions with: Flaxseed. University of Maryland Medical
Center. Retrieved from: http://umm.edu/health/medical/altmed/supplement-interaction/possible-interactions-with-flaxseedoil
Yoder, J. (2013). Lipids Chapter 5: Function, Structure, Digestion, Transport Metabolism [PowerPoint slides]. Retireved from:
https://blackboard.ohio.edu/webapps/portal/frameset.jsp?tab_tab_group_id=_2_1&url=%2Fwebapps%2Fblackboard%
2Fexecute%2Flauncher%3Ftype%3DCourse%26id%3D_294775_1%26url%3D.