MAYO, OFELIA Q.

BSN 041/ GROUP 164

GENERIC NAME BRAND INDICATION CONTRAINDICATION SIDE EFFECT NURSING CONSIDERATION
NAME
Chloramphenicol is This medication -Do not use for trivial infections,
BRAND -To treat serious contraindicated in may temporarily highly toxic.
CHLORAMPHENICOL NAME infections due to individuals with a history of cause redness, -Refrigeration recommended.
150 mg/ every 8 hours (S): organisms resistant previous hypersensitivity irritation, itching - Do not give salicylates or NSAIDs
Elase- to other less toxic and/or toxic reaction to it. or swelling of the while administering this drug.
Chloromycetin Kapseals Chloro area. If these
antibiotics, or when
(chlorampenicol) mycetin symptoms DOSAGE RECOMMENDATION
its penetration into continue or
Chloromycetin Sodium the site of infection become Chloramphenicol palmitate) 25-90
Sumlinate is clinically bothersome, mg/lb , PO, q8hrs 4
(powder for injection) superior to other inform your
antibiotics. Those doctor. Notify Chloramphenicol sodium
CLASSIFICATION: bacteria sensitive to your doctor if sumlinate)15 mg/lb to 25 mg/lb ,
Antibiotic this drug include you experience a SQ or IM, BID for 7-14 days 4
clostridium, skin rash,
chlamydia, breathing trouble, (Chloramphenicol palmitate)50
1
mycoplasma, unusual bruising mg/kg to 200 mg/kg , PO , q8hrs
2
or bleeding,
salmonella.
weakness. If you
notice other
effects not listed (Chloramphenicol sodium
above, contact sumlinate)30mg/kg to 50mg/kg ,
your doctor or SQ or IM , q12hrs 1 11
pharmacist.

COTRIMOXAZOLE
150 mg/ BID

Sulfamethoxazole and -hypersensitivity -contraindicated in patients with

-treatment of
trimethoprim; cotrimoxazole
CLASSIFICATION:
Antibacterial
infections due to
susceptible organisms -hematologic toxicity: reactions known hypersensitivity to
BACTRIM, neutropenia, trimethoprim or sulfonamides, or
SEPTRA
thrombocytopenia, -pain, local with documented megaloblastic
agranulocytosis, aplastic irritation, anemia secondary to folate
inflammation, deficiency.
anemia
and rarely
thrombophlebitis -dilute each 5 mL ampoule with 125
-contraindicated in mL of D5W or NS, the prepared
patients with known solution must be kept at room
hypersensitivity to temperature (solution stable for 24
trimethoprim or hours)
sulfonamides, or with
documented -in fluid restriction: each 5 mL
megaloblastic anemia ampoule may be diluted with 75 mL
secondary to folate D5W or NS (solution stable for a
deficiency total of 3 hours, inluding infusion
period)
-use with caution in
patients with impaired -each 5 mL ampoule may be diluted
renal or hepatic function with 50mL D5W or NS (solution
stable for a total of 1.5 hours,
or with possible folate or
including infusion period)
G-6-PD deficiency
-discard if there is cloudiness or
precipitation
DOSAGE RECOMMENDATION
-hematologic toxicity: neutropenia,
thrombocytopenia, agranulocytosis,
aplastic anemia.
-use with caution in patients with
impaired renal or hepatic function
or with possible folate or G-6-PD
deficiency.
 Cotrimoxazole is a fixed
combination product containing
sulfamethoxazole and trimethoprim
in 5:1 ratio.

Pneumocystis Carinii Pneumonia:-

Adults and children: 5 mg/kg
trimethoprim (as cotrimoxazole)
every 6 hours

Gram-Negative Sepsis:

-Adults: 2.5 mg/kg trimethoprim (as

cotrimoxazole) every 6 hours

-Dosage interval must be

lengthened in renal impairment:
(2.5-5 mg/kg/dose)

ROUTES OF
ADMINISTRATION

IV intermittent - over 30-60 minutes

HYOSCINE
BUTYLBROMIDE
½ ampule/PRN
-relief of smooth
CLASSIFICATION: muscle spasm of the -contraindicated in -tachycardia
gastrointestinal and glaucoma
-contraindicated in glaucoma
Antispasmodic BUSCOPAN, genitourinary systems
-other adverse effects
scopolamine -other adverse effects include: dry
include: dry mouth,
butylbromide mouth, decreased perspiration,
decreased perspiration,
mydriasis, increased intra-ocular
mydriasis, increased intra-
pressure
ocular pressure
-use with caution in prostatic
-use with caution in hypertrophy
prostatic hypertrophy
- stable at room temperature

ROUTES OF
ADMINISTRATION

IV intermittent - over 30-60 minutes

DOSAGE RECOMMENDATION

Adult: 10-20 mg; may be repeated

3-4 times daily

ROUTES OF
ADMINISTRATION

-SC injection

-SC infusion - See Policy for

Administration of Subcutaneous
Infusions

-IM

-IV direct - administer 10 mg over at

least 1 minute

-IV intermittent