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Treatment

Thereisaplethoraoftreatmentsforbreastcancer.
Specifictreatmentsarechosenforspecificcasesofcancer.
Hereisalistofthemostcommontreatments.

Breast Cancer
(Gene BRCA1)

Bibliography

By:JackDeMarco

Surgery
Chemotherapy
RadiationTherapy
TargetedTherapy
Immunotherapy

1.

http://newsnetwork.mayoclinic.org/files/201
4/04/shutterstock_155269400.jpg
2. http://www.cancer.org/cancer/breastcancer/
detailedguide/breast-cancer-what-is-breast-c
ancer
3. http://www.ncbi.nlm.nih.gov/books/NBK1247
/
4. http://www.ncbi.nlm.nih.gov/pmc/articles/P
MC3005727/
5. http://www.nytimes.com/health/guides/disea
se/breast-cancer/print.html
6. http://www.integratedhealthcare.eu/1/en/brea
stcancer/1512/
7. http://en.wikipedia.org/wiki/Cancer_syndrome
#mediaviewer/File:Autosomal_dominant.png
8. http://www.intechopen.com/books/future-asp
ects-of-tumor-suppressor-gene/to-grow-stop-o
r-die-novel-tumor-suppressive-mechanism-reg
ulated-by-the-transcription-factor-e2f
9. http://www.cancer.org/treatment/treatmentsa
ndsideeffects/treatmenttypes/treatment-types
-landing
10. http://www.nationalbreastcancer.org/breast-c
ancer-treatment

Detailedinformationonthesetreatmentscanbefound
at:
http://www.cancer.org/treatment/treatmentsandsideeffects/t
reatmenttypes/treatmenttypeslanding

10

Is Breast Cancer life


threatening?

Theshortanswertothisquestionisyes,unfortunately
thisdiseaseisfatalifleftuntreated.Thecancerouscellswill
continuetospreadandmultiplyuntiltheaffectedindividual
dies.

Fortunatelythetreatmentsabovecanhelpstoptheabove
fromhappening!

Symptoms

What exactly is Gene BRCA1?

GeneBRCA1isatumorsuppressorgene.Thismeans

What is Breast
Cancer?

theytellc
ellstoslowdowncelldivision,repairDNA
mistakes,ortellcellswhentodie.Thisgeneislocatedon
chromosome17.

Changeinbreastornippleappearance(Recent
asymmetry,rednessofskin,unexplainedchange
inshapeorsize)

Breastcancerisamalignanttumorthatstartsinthe

Changeinhowthebreastfeels

Anynippledischarge

cellsofthebreast.Amalignanttumorisagroupofcancer
cellsthatcangrowinto(invade)surroundingtissuesor
spread(metastasize)todistantareasofthebody.The
diseaseoccursalmostentirelyinwomen,butmencanget
2
it,too.

What causes Breast Cancer?

Mutationsthatturnon
oncogenes
orturnoff
tumorsuppressorgenes
.
Mutationsinthetumorsuppressorgenes
BRCA1andBRCA2cancausebreastcancer
MutationsinBRCA1andBRCA2canbe
hereditaryandpasseddowninanautosomal
dominantmanner
environmentalfactors
likeradiationand
carcinogenscanalsocausemutationsin
oncogenesandtumorsuppressorgenesthat
causecancer.

Facts about disease

Estimated1.4millioncasesofbreastcancer
worldwide
BreastCancerismorecommoninwomen
Breastcancerisdiagnosedinallpartsofthe
world
Breastcancerisdangerousbecauseitisso
easyforittospreadtothebones,lungsand
otherpartsofthebodythroughthelymphatic
system

Pedigree

of brca1 gene mutations:

Ifyouorsomeoneyouknowhasanyoftheabove
symptomsyou/theyneedtovisitadoctorimmediately
asanyofthesesymptomscanindicatebreastcancer
anditisgoodtocatchcancerearly.

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