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TTR GPT Her a, Fever ws, yfkeror whe ate aex wie eather ergPeer gett wh ree area aR 1 we Ve ATA TeeTe AY rte & Pe aE eae afin # Rey are Pade ar ga ere & oTeTT a eT 7 BTA BIEL Raerecnh aor eh arte a aregtecr eh ae are, Rereret afer arr erly, fore arr weere gfieenr ait areceghy oh ery, wh rere B 1 sare" AL are ar! # scches wer 2 sfas'C! seer ger A afar amr | aeker THe GRR BT FLMC ous 25% Hae H fora aT | acter wer & at are fewer fey my B 1 gat a aaer gam Rewer OY “ae svat erator wer” B 1 aareest seater sre wr wet spear eraleerr BH eA BI Teer rh BV safer eT aT SOT Be By ae are, ar sea re fy S feng srary opera on wea Bf cent a ew = & silat ae site ae a ae frern ay 1 vGier erarer Bh cart oe wet GPReroT site wee aw sPrrCActer wr sraeT eta DATE aoregeter aor seri wet aw argh ae | ‘Preht sree a Pasi a meh araroht eeemeor seer TT 1 aan Ber argh Ts CATION wt HF ATP ora & 1 ‘$146 BU/13-3BH—1A, ‘8/46 BJ3-3BH—1B 1 srt ‘#' / PART ‘A’ ow Get fr Ae a at aw Ah tant wach gf wd am a ae ad Ted a Oa 81 ta set & abet & ga deme a s ‘An ant goes from A to C in the figure crawling only on the lines and taking the least length of path. The number of ways in which it can do so is a e . jc 12 24 35 4.6 att oui ae aderay afer A wa fig after ey a get ont toga fig a Arras OABH ase A safer Far BP (agi ZA0B = x tBu &) ib Be x x a az 3. A point is chosen at random from a circular disc shown below. What is the probability that the point lies in the sector OAB? (where ZAOB = x radians) 2 2. 2 = 4. ~/ V SR aeiter gar eig-arene att AY ara V Sl ag araet Sag % amd aH et F ser aren ater A ore ar atreretet F » Spat v v lL. it 2. a v v 3. a 4. al The capacity of the conical vessel shown above is V. It is filled with water upto half its height. The volume of water in the vessel is v v L at 2. nm v v 3G 4 Asa Row atatea ‘ahr a at oay uerafafer war srarer fervor, anaferer PARROT a ania fraraar & (Prt a aa) apr aafetet for a aifar ouafa Per a dtr Fr eran & LR 2. RV2 3. 2R 4. RV3 A tay of light, after getting reflected twice from a hemispherical mirror of radius R (see the above figure), emerges parallel to the incident ray. ‘The separation of the original incident ray and the final reflected ray is LR 2./ RVD 3. QR 4. RNB aR Tar 8 Rea, Bet ser, 2 Rea. aie A wa caftta fate aa A sar 2a. 81 Wa A Fo sta Gwar se see TAT aot Ff aidt ore 10 Praraort are fate aren siffaisa a ser or Poe a ate whet a idl ar srareT: 1/20at 1/10aF, ait at ued 1 oe & stat fate aT aot 9.25 Pam. Gem aml Bae Ay Py Pam. Bet Fy aT A? 1. 0.5 kg. 2 1 kg. 3. 2 kg. 4 3 kg sow io fee Bis ee We eae 5. A king ordered that a golden crown be made for him ‘frditi.8"kg'of gold and 2 kg of silver. The goldsmith) took away some amount of gold and replaced it by an equal amount of silver and the crown when made, weighed 10 kg. Archimedes knew that under water gold lost 1/20" of its weight, while silver lost 1/10" . When ‘the crown was weighed under water, it was 9.25 kg. How much gold was stolen by the goldsmith? 1. 05 ke, 2. 1 kg. BoD kee A 3 kg ve ah AY Fore er er, ah aly a ae No wir, 7:35 aot war 8? 1. 0° 2. 175" 3. 19.5" 4. 20° What is the angle between the minute and hour hands of a clock at 7:35? 5 . Pl 1 0 2.17.5" 3, 19.5" 4. 20° fot a at Reet ofaat A aefat A ica i 2. 13420 ; 4, 10m i. 1. 127220 3. 13aer21 2 In the figure below the numbers of circles in the blank rows must be 1, 1and 20. 2. 3. 13and21 4. 13 and 20 10 and 11 aft ga we teres A fat aed & art (w) waive 3irg (t) at air aR Bat fare eet aet are tanfat a ater at wet ort amet or RA? 1 2, "Le A If we plot the weight (w) versus age (t) of a child in a graph, the one that will never be obtained from amongst the four graphs given below is 1 2 “bo "NAL yet ser aT set wet 32 43 5 9. Find the missing number: BPR 0 32 4.3 10. wa afaera weir x? + axtb=0 at Ft aed ge UH Raat A oat aed ATT AAT aR 6 cer 2 oa wate gat faaet a b Br Waa Alar AT ATG TAT 1 A o TT b & et Ara, HAM: Fa FP 3 mer 4 8 ae 12 1. 79120 2 3 -7aMI2 4. 10. In solving a quadratic equation of the form x? + ax+b=0 , one student took the wrong value of a and got the roots as 6 and 2; while another student took the wrong value of b and got the roots as 6 and 1. What are the correct values of a and b, respectively? 2. 3and4 4. Band 12 1. 7and 12 3. -7and 12 11, diftat ar we war, fig A a B fig ae wach &, cer set ced & Ag A aT aid 81 eat diftat want aft a Tach & ar Raft aft Rig oe oe Saws at vifeat war fer A ore det Bi uw eid aT AT B am art 4 ve fae ore bi fare ater & ASB am & aa & aha ag Pract a ait @ difeat a rash? 1. 120 2. 60 3. 240 4. 180 11. A stream of ants go from point A to point B and return to A along the same path, All the ants move at a constant speed and from any given point 2 ants pass per second one way. It takes | minute for an 1. Aonly 2. B only 3. Conly 4, Aand Bonly 14, aaret fr ayoraTerat (x + ys) (Xe + Ya)s++(Xa0 + Yoo) at aig Rega wed BI Pet WA oe ahr ant to go from A to B. How many Barret Soar oe xara are Bat y eA? returning ants will an ant meet in its 1a 2 5 Joumey from A to B? 3 10 4, 20 1. 120 2, 60 14, Suppose you expand the product (xs + ya) (x2 + Y2)+++(X20 + Yao). How many terms will have 3. 240 eee only one xand rest y’s? 12. et & a war ad df at oft aoa 205 e hal 3. 10 4, 20 feet at BS oe A A one ore ar sere ‘art rar srar Br Aree Veit as ae cr 410% & ate geht we sea? 1, 3. dt 12, A large tank filled with water Is to be 15. a aagut & dea afr aft 6 fm a 81 2a 1:50000 een 4:5000 areas: & araett a ards 45 are ft aftat mare: war gah 1. 12a, aerd.2 Bat. emptied by removing half. of the water 2 2 daft, cera2 Wat. present in it everyday. After how many 3. 120a.a, aer12 Bah. days will there be closest to 10% watar left 4, 129M, aer120, a, in the tank? 15, The distance between two oil rigs is 6km. 2} One 2. Two What will be the distance between these 3. Three 4 Four rigs in maps of 1:50000 and 1:5000 scales, 13, ner smear aiear BI af nf Fawr 8, at respectively? freer Har wet 1, 12emand 1.2m (A) n fawar & 2. 2 emand 12cm (8) n? far & 3. 120 mand 12 om P 4, 12emand 120 cm (0) nt wae 4. eA 2 aaae 16. WH 16.2 a. ot aes & Ge a 2 a. 3 ear 4, faa wer B Hee care Bl wa gas, For sire 22 ua at, 8 at ort & fae ge a fara 13, nis a natural number. If n° is odd, which of ‘tert apreaT aTgT? the following is true? 1. 3.5m, 2. 7.0%. (A) nis odd 3. 14.07 4, 22.04 (B) n° is odd (C) n‘iseven 16. v7. a 18. 18. 19. ‘A 16.2 m long wooden log has a uniform diameter of 2 m. To what length the log should be cut to obtain a piece of 22 m* volume? 2. 7.0m 22.0m 1 3.5m 3. 14.0m 4. Thar atte aim aT BP 1.7 2.9 3. 3 41 . What is the last digit of 7°2 2.9 41 1.7 um nivaarer ager at each ApIait & af 6 efosat Pech 1 set on A eat Aprait Fr Heart war: 60, 30, 20 ae 15 FI ae wp fruit war 8, at aratt at eset F eavh-aprait ft aigard gar et wat # 1. 1045 2442 3. 15415 4. 12410 ‘A lucky man finds 6 pots of gold coins. He counts the coins in the first four pots to be 60, 30, 20 and 15, respectively. If there is a definite progression, what would be the numbers of coins in the next two pots? 4and2 12 and 10 1. 10and5 2 3. Wand15 4. we ayaa set ofear at Ys ated wer 30 fRae afar A aeR SEAT UF wam # ufaar cia fac & fae AY wea adit 8 agra ag ou # 20. 20. aan 40 fae seat UH Gat seuret A 10 fae & fe ay wef ah BP ae wad frencaa Ted B aoe Sear Oe aT aict &1 ae arent ge fe Ae sae aie a sect 8, ag sat Year A Rar ware & FAT ay UE? 1. 85 fae 2 3.135 ae 4. 155 fare 1 ae oar ). A bee leaves its hive in the morning and after flying for 30 minutes due south reaches a garden and spends 5 minutes collecting honey. Then it flies for 40 minutes due west and collects honey in another garden for 10 minutes. Then it returns to the hive taking the shortest route. How long was the bee away from its hive? (Assume that the bee flies at constant speed) 1. 85min = 2, 15S min 3. 135min 4. Less than | hour 12 A. Sag & ww ts F a BS OH vat, os 1 Sarg & Geet a we a os 82 & ait weet ww erage at gud B1 vet arama at oenget wa aie Tar ae Sect 1 aft chat ar aferat war &, at as & Se 2 Reet aft oe erate oat B ses STAT? 9a 14 1. 16 a. 2 3. 12 a. 4. A bird perched at the top of a 12 m high tree sees a centipede moving towards the base of the tree from a distance equal to. twice the height of the tree. The bird flies along a straight line to catch the centipede. If both move at the same speed, at what distance from the base of the tree will the centipede be picked up by the bird? 1. 16m 3. 12m 2.9m 4. 14m a. 2. 22, Sharopitsh T4°¢, anteng at centre ae sitar at vary atten a wfaee aT gar Bl aeneare Pasty Fr Stet ar says het arereensit A ghar OL aearer TNR (immediate carly), 3iTéftar (early) aie farcifaet (late) | wet wef fearsroy sfetler ur eat ath faq ee 8, fae sit fasiaor eter & 1, atlas erated FAT ATL 2, anfeeer ae wat! we oifearter a SoROT BRIT | . ardter oferta a dectqor FAT | Se Wat U Bea VHT FT ae RT Bacteriophage T4 infects Z, cali and injects its DNA inside the cell, The transcription of viral genes occurs in three stages: immediate early, early and late, All the promoters on viral genome are available, but the control takes place at the level of : 1, promoter strength. 2. modification of host RNA polymerase, 3, synthesis of new polymerases, 4, turn over rate of RNA synthesis, elon ae wale SRST aT O-STTR 4 1. seater ore adh aaT Bote Sitar a Aer aed fe sre F 2, wis tanga, ater a ofa aya. ad ag wera & 3, ws targa a eae tore a sider ah aT F Pe 4a tet 8 seaeuirar ae safe hr faftecar afaitaa ae aret f 22, o-subunit of E. coli RNA polymerase DOES NOT 1. initiate transcription and fall off during elongation. 2, increase affinity of the core enzyme to the promoter. 3. binds to DNA, independent of the core enzyme. 4, ensures specificity. of transcription by interacting with the core enzyme. 23, ein sirderat sdter (cIP4E), ait eereafareor (translation) & ardtrar fairer Y wae 8, aaa aansit a oredr fer at th ew gain at RM sheet a ahaventt eeerhfeat.Ay ayaa ay elFAR aftr & aa aga ATA a StarmeMfagT — (transfect)... ATH. BAA woraer airand aeitstr 1, VaR HRAT (apoptosis) 2, AaRSAT BATALT (neoplastic {transformation} 3. arg oRader aét 4, fastener 23. The cap binding ‘protein (eIF4E), which is involved in the global regulation of translation, is highly regulated inseukaryotic cells. In an experiment, a researcher -_ transfected mammalian cells with (eIF4B) gene for its ‘overexpression, Due. to this, the cells will undergo 1, apoptosis. 2, neoplastic transformation. 3. no change, 4, differentiation. 24, Hohe ast ar oRatier ara a fae, spits eear alftransit ar sifredaor qaer woot & afteata & fae fear stat Bl ga aes ar aaa fear star = 24. For developing transgenic mice, embryonic stem cells are engineered to express the transgene. These cells are selected by 1. novobi 2. neomycin, 3. tetracycline, 4, penicillin, 25.7 TH far, §—Fatfewreberr FPN (Klebsiella pneumoniae) FSA F tear art & He wel H we aeat ‘WaT WaT (severe septic shock) FAT Bl Ba wat & tar & fae far a a salaat wert wet ae G7 1. aiRreniifer sirafas arectarefecit ar aft seme aa FI 2.ae sat wT SvER we-TNFa wfattst gare ferar st werat & 1 3a gE & svar tq yah Shenftaa viet ar suet fret oT weet FI 4. mort vera & soe & fae qatar TNFa - arér fae ar soeter ear oT wre F | 25. Gram negative bacteria, Klebsiella pneumoniae, upon infecting humans, results in severe septic shock after a few hours of infection. Which of the following is not true for this type of infection? 1, Cell wall endotoxins cause overproduction of cytokines, 26. 26, 21, 21, 2. Septic shock can be treated by anti-TNFa antibodies. 3. Recombinant bacterial proteins can be used for the treatment of septic shock. 4, Recombinant TNFa receptor antagonist can be used for the treatment of septic shock, for a a stadt Ree afar afatiar & tag agt areit ret 8? 1. Ser ar vaRtst GRageT | 2. wer Ea Tests feratteT | 3. tar SoH A. agr EST TUT-HTGEA | 4. Tepre-arersraret BY wet eX | Which of the following is NOT associated with insulin action? 1, Increased glucose transport. 2. Increased glycogen formation, 3. Enhanced lipolysis in adipose tissue. 4, Decreased rate of gluconeogenesis. qenctea franca A angst a fare # sie seer usr te OW qenshfaat a vara gant eet 81 efta Pie Re fees a a steer shay ait (copper) #T gee area B freee F URIS WeTeT LAT BP 1. Acidithiobacillus ferroxidans. 2. Pseudomonas putida. 3. Deinococcus radiodurans. 4. Rhodopseudomonas capsulate. Microbial leaching involves the process of dissolution of metals from ore breaking rocks using microorganisms. Which one of the following bacteria helps in leaching copper from its ore? 1, Acidithiobacjllus ferroxidans, 2, Pseudomonas putida, 3. Deinococcus nadiodurans, 4, Rhodopseudomonas capsulate. 28, fret A aptarer oRaroy antes, anferhr dehrr srqere chagindy qanr atrafter ah fare Gt BERET 1H. 2. P, 3. "o. 4, BN. 28, Which of the following atomic nuclei cannot be probed by nuclear magnetic resonance spectroscopy? 1TH 2. IP, 3, Ho. 4. 5N, 29, ret saqearoter sent wag sfafmeT, SoP HT typ 1 Ber Bl ge Peat A 75% qian wet ara & fee aioe wr (det #) ear 1.15 2. 2.0, 3, 2.5, 4. 3.0, 29, tin of an irreversible first order reaction, SP. is 1 hour, ‘The time (in hours) required to reach 75% completion is 1. 15. 2. 2.0. 3. 2.5. 4. 3.0. 30.257 nm OX thier Confer aT ST Haetrsor apts 200 Mom" eat Sl sferet ise fe se see ree aT aater-aT BAT 257 nm VW, 0.5-cm Ter FY sens AY after #1 staeitsor werer ate? 1. 3.30. 2. 0.33. 3. 1.68. 4. 0.17. 30, Molar absorption coefficient of phenylalanine is 200 M'cm” at 257 nm, What concentration 10 3h 3 (g/L) of this amino acid will give an absorption of 1 in a cell of 0.5-cm path fength at 257 nm? 1. 3.30. 2. 033. 3. 1.65. 4. 0.17. aigiaatar anette (hybridoma technology ) A uagohel vfaftis seoreet 8 arerae oy, srr F og ag aractar atenait 7 ergulaifreret-sarettet premiere gimtst (HGPRT) tanga &Y ga dat car aah elat & fr data arene aait seid we wach Fo we Serr TET prsdisteeiter. arelteeeRet-erg fasta (HAT) ae fear sme! ge Hemet FH sratteticefter (aminopterin) AY syferer ar eet 8? 1. Arretar aiensit & ater aa dare & wo A seater star | eafrertarget ft deeteor after at HavG FAT | aractar vented Baraat ae vfafis sera atransit ar efor grater | wfefis scart B aftrarsit a Tee PTT | |. In the case of monoclonal antibody production by hybridoma technology, myeloma cells used lack the enzyme —hypoxanthine-guanine phosphoriboxy! transferase (HGPRT) such that fused cells can only survive when selected on hypoxanthine-aminopterin-thymidine (HAT). What is the role of aminopterin in this medium? 1. To be used as cell cycle inhibitor of myeloma cells. 2. To block the pathway for nucleotide synthesis, 3. To facilitate fusion of myeloid B cells and antibody producing B cells, 32. 32. 33, 33. 34. 4. To facilitate production of antibody producing B cells. fart A & ate daft B- wd T- after arqutar are sme #2 1. tarfmaneaistee rar 2. Rae war ar toranategiaatrar 3. faeate-ufege dearer 4. deat ar Corarscteaioairar Which of the following is considered to be a combined B- and T-cell deficiency? 1. Ataxia-telangiectasia 2. Swiss type agammaglobulinemia 3. Wiskott-Aldrich syndrome 4, Bruton's agammaglobulinemia ye A aor ar ag amt fet arene, east FR Ud sfeerer a fear erat &, agora & 1, anf tar | 2. sea | 3. afttetite | 4, sae | The part of the embryo from which the ectoderm, mesoderm and endoderm are formed in chick is known as 1. primitive streak, 2. hypoblast. 3. epiblast. 4, cytotrophoblast. oa taeAT (adenoma) Arete UatettanfeaitAT (metastatic adenocarcinoma) Hakata et creat &, at fawr a a aaa attat ar deter avert faite wo & arate a ore 1, aetoret wa IV ate Aihara 2. wigstaitcat Ua p, sefaet 3. Aeratsiferst ud Ber stews 11 4, wonfteat Ud Tasca 34. When adenoma is converted to metastatic adenocarcinoma, which of the following combination of proteins is almost certainly to be degraded? 1. Type IV collagen and laminin, 2, Fibronectin and Pp integrin, 3. Metalloprotease and serine protease. 4. Elastin and selectin. saaett tron cant wfaa ata steer aie teanfaert wea ar deat ae dfte san Prater at sdifta act ee 1. paket | 2. atta | 3. Barton | 4. Sees | Which protein secreted by the amphibian organizer induces neural tissue formation by inhibiting Bone Morphogenetic Protein? 1. Becatenii 2. Noggi 3. Dickkopf. 4. Dishevelled. BRAT (Drosophila) A Bae aT waar gat & 1, HAM AT (Fushi tarazu) | 2. tertes | 3. smear | 4. aafeee gees | The homologue of f-catenin in Drosophila is 1, Fushi tarazu, 2. Engrailed 3. Armadillo. 4. Cubitus interruptus. 37. a deat Way A sk BA fT a 8 aaa aniieftar 35. 35. 36. 36. seateatrent sae anor a ah a vier wae aiftiar dady err #7 1A ate 8 eng afage ¢ att regis wet & UE EA 2. Ste BY axe srectieper ett F ate aor ag feat & wee EI 3A aie 8 aroteiger et & ste war gat at faenfter aed F | 4.4 ait a arckiter et & athe var at at aratter ara & 1 37. Which one of the following non-covalent interactions between two non-bonded atoms A and B is most sensitive to. the distance between them? 1, A and B are permanent dipoles and are involved in hydrogen bonding, 2. A and B are fully ionized and are involved in salt bridge formation. 3. A and B are uncharged and repel cach other, 4, A and B are uncharged and attract each other. 38, wheteit a srattat taygh & pkade wafer career faesr a Wt atersan Sherer aptar t7 1. asa BAR Bh ypkia e-aTete Ay & pKa sea Mar Fy asriat Bag FT pKa estat way % pKa® fare eter & | osat WA BT pKa estat wa & pKa & wareer ser | ota BaE aT pKa SMfetefter ar vated aed sfgrar & pKa & ser Bat FI 38. Which statement best describes the pKa of amino groups in proteins? 1, pKa of a-amino group is higher than the pKa of -amino group. nN 2 12 3 2, pKa of a-amino group is lower than the pKa of e-amino group. pKa of a-amino group is same as the pKa of c-amino group. pKa of a-amino group is higher than the pKaof guanidine side chain of arginine. . seer 3/AREEt (ap3/pi) seaRadet apler-et ys uar vanfaer eter 8? 1, areager att gor 2. cer ate fae 3. faree site GAT 4, areaeet aie free Which of the floral ,whorls is affected in apetala 3/pistillata (ap3ipi) mutants? 1. Sepals and petals. 7 2. Petals and stamens. 3. Stamens and carpels, 4, Sepals and stamens, aigdaiieger ot 2, asrgarghfteter a war ware eat 8? ve tag waa fara ar ae ay far geagrar oftamer ar aiaviet feet are aeduor at sae HT Sa HL 2a safer argelatieger et a HIRO ATP-ADP ar Patera aha Re geagia oftage sit arp aeayor at aftr axa & | 3.u¢ sft 1, He mn ae seagter aftage atte ict dua at after art & | 4. ATP faetor & ateahe aerate fer aren & ate sehr HART aT daft wea e | 3. 4. s 40. 40, What is the effect of 2, 4-dinitropheriol- on mitochondria? 41. 41. a. a2. 1, Blocks ATP synthesis without inhibiting electron transport. by dissipating the proton gradient. 2. Blocks electron transport and ATP synthesis by inhibiting ATP-ADP exchange across the inner mitochondrial membrane. 3. Blocks electron transport and proton pumping at complexes I, Il and II] 4, Interacts directly with ATP synthase and inhibits its activ a ea yout cect & dre dar armen war) GROTARTET EF Bafa HIST ane iar aaa M1 ear NTE 1. ATRUT | 2. qerafsret | 3, Fara | 4, Teme | ‘Across is made between two plants with white flowers. All the F1 progeny had red coloured flower. This is because of 1. complementation. 2. recombination. 3. translocation. 4, reversion. fret siela A 30% Vonfeer faquaret & afe ast tera at vorgftat cant eeraiafta ae fear are at 1. psfeeht anda ag SIT | 2. pmax ada ae STE | 3, dear a ans oRacer ag ee | 4, torfaaeaaiatta ste, ser steer & geet A wa wfea ett | A protein has 30% alanine. If all the alanines are replaced by glycines, 1. helical content will increase. 2. Besheet content will increase. 3. there will be no change in conformation. 4, the alanine-substituted protein will be less structured than the parent protein. 13 43. 43. 44. 44. denise aa (Asp) aT FafaeeeaeT wiiq GAU wd GAC ant aa ZI sertada & sia, Asp ar Wace OH tora A a sat & HR GCx gant frefta far svar &, set x eh Bema & A,U, C Hua G, seaRada ar wearer art fRenefte sttediort onfeat gant é aire G1 te A seaftacter Ar wepfer aiichr oret & 4. SaATT | 2. HET | 3, AoA FAAT HTENT | 4, cagafagtettaeor (depurination) | ‘Aspartic acid (Asp) is specified by the codon GAU and GAC. After mutation, Asp is changed to Alanine represented by GCX, where X may be A, U, C or G. The reversion of the mutation could only be done with reactive oxygen species. The nature of the mutation is considered to be 1. transition. transversion. either transition or transversion. depurination. 2. 3. 4. FAST (Cladistic ) Aaa HT HE Langeite at Ge eet ww safaqedtar gat & scueat echt & | 2. arapnat faate aT a | 3. sranfthre aaror va cafseat ar SSRI 4, are doa va Ureettsy | Cladistic classification is based on 1, sequential order in which branches arise from a phylogenetic tree. 2. the order of sequence divergence. 3, morphological features and skeleton of individuals. 4. cellular organization and cytoskeleton. 45, Fart geet etch gS safer oer var & fac fer a a att ar warden soeler A are sire 8? 1. edie woreret | 2. srepfetan eet | 3, wfearertrer seater | 4.8 woe | 4 a Which of these programs is ised to conserve a species facing extinction? 1, Captive breeding. 2., Natural resources, 3. Sustainable use. 4, Bdge effects, Yricera(Tautonym) war tar steitrenftas aftr yeaa & sit sot wnforat a fore Sureiar fren siren & fret 4, der ud ser ar vas @ arate | 2. safer va sooner ar var é art et | 3, Prema araracor fear ara et | 4, Aawlauthor) ar aT one few fear aren et | Tautonym is an informal _ taxonomic designation used for animals referring to 1, same name for genus and species. 2. same name for species and subspecies. 3. trinomial nomenclature. 4, the name of the author for the species. fat wapte stadoniers at ag AY Tae BUH yeH seq Glo fare ga a wt ate ware: wa sik ay, soit car ag, ote caurggd al Ra ow pt wen dt wd AR uve da at faquaret F vg wer ware seater aml ga acer Be sree W sig wetter eat FT 1, aARE | 46. 4 R 47. 2, Tierephr | 3. agree (He) | 4, veered Greefereng) 1 47. A marine biologist dug up a small animal from the ocean floor. The animal was uniformly segmented with short, stiff appendages and soft, flexible skin, It had a complete digestive system and an open circulatory system but no exoskeleton, Based on this description, the animal appears to be a » lancelet. . roundworm. . mollusc. }- crustacean, eR 48, eget ft war Seiwa wr Sra WATT Rreaarafragaiagor fae cant fer oH er Sl went fea, fafeve ata A wa dt @ arafr a 100 Rest ar vaeTT, fees ate arantear fren arr) at at yntagor & vez, set safe sty ser ate Y 10 fafeea ate 90: fea fad fegs. gor wa? sire Afar fafése aa a oeriear a sree FT eer 1. 80, 2. 100. 3. 1,000. 4. 10,000. 48. A grasshopper population is being assessed by capture-mark-release-recapture method. On the first day, 100 grasshoppers were captured from a given area in 1 hour time, marked and released, On the next day during recapture, 10 marked and 90 unmarked grasshoppers could be found in the same time period from same area. What will be the estimated population size in the given area? 1. 80, 2. 100, 3. 1,000. 4, 10,000. 49. 49. 50. 50. 51. Fecha agit «= due fafaer uaa fart A scott at we wad 1 at a es ah a a aeqt Rasa Ff yea Fe 1, Oonetdeer— HAT FET | 2. Surfer entra Aer | 3. argon fare HFA FET | 4, shaver seretet Fer | Free-living nitrogen fixers can survive in different ecological niches. Identify the incorrect combination from the following list : 1, Azotobacter — acidic soil 2. Deraxia — alkaline soil. 3. Beijernckia — acid soil. 4. Frankia - neutral . Sat & aot S Belts va ACT Us ar aft GaAs (oyster mushrooms) @aNT aatoor fear aa UR Acae AH SNIcT 95% 8 sftren aga Witte erggharda ferrfet atfteat a arrefea ef ye a1 ag via ager F 1, TESTER | 2. TATASTIRT | 3. HERSTIRTT | 4, MIARTSTART | A plot of soil contaminated with diesel oil was inoculated with oyster mushrooms. After 4 weeks, more than 95% of the polycyclic aromatic hydrocarbons had been reduced tc non-toxic compounds. This process is called 1, phytoremediation. 2. chemoremediation. 3. mycoremediation. 4. zooremediation. wemfattst at ga freee daroT aTawA(Tm) TAT HET AaoT WT PAT arat &1 ga oes 15 51. 52. Laat oiemfetet ar Tm ar 2. DPPC @T Tm ferret afk DoPC FT seaam err 3. Popc Wd DOPC @T Tm Vaart ear aferet DMPC Heat PCCW fare eT 4. DoPC #T Tm wa atk ppcc aT Tm 3eqan eT | wearer The gel liquid crystalline transi temperature (Tm) of | phospholipids is dependent on the fatty acid composition. Considering this, Tm of 1. all the phospholipids will be identical, DPFC will be lowest and DOPC will be highest. . POPC and DOPC will be identical and lower than DMPC or DPPC. DOPC will be lowest and DPPC will be highest. gros A sieht aro ya A, faeiiea- ereisit (peppered moths ) #1 GT seat BAT ar worded f gee Grunt gait six tarst & fase wert wo & aerate (camouflaged) @t aia M1 sttqahftrer swifer & wea sete dam at ar aw oa fr gait oe threftat (factories) AY Feat wrt 8 ¢ ae os av ak wa areata BT A we aT Gar A ere ae ae) tar BT 1.oner A amar dear FH Peewee eresit A a at tmnt emt & mgt ROT BRT | 2. aTaTRONT TENT & HEAT ery aT seaRadet BRT | 3. qrareaoha ofa & woeaer abt are geq-facnrea a BRT | to 4. eet AY -wereroher frenfafe a wrepfcras aor ay eAIOT | 52, In pre-industrial period in England, peppered moths had light coloration which effectively camouflaged them against’ light coloured trees and lichens, . During. industrial , revolution, many lichens “died out and’ ‘trees became blackened by soot from factories and interestingly, dark coloured moths were predominantly seen, ‘This happened due to natural selection of dark coloured moths which were initially piesent in fewer numbers. 2. new mutation which arose due’ to environmental pollution. 3, macroevolution occuring’ due to ‘environmental “change. 4, natural selection of the caiiouflaging mechanism of the mioths, SNA rp aireeTet BF Sher Tar Torset rare Prat & at lac aifatex a freraray feretroT HH Reeder saziedwor vergat at wa axer OI sta Aire fa ferret O staat oRituiaat a se fate A, sit “seta & Reece Rear aire ain tare at are acl nee et & siqafeers ed #1" 2.mrF aa aa Aaehe athe copter 'etat & safeea aa FI 3.4 aa oa dache at areqaieat eat & atte aagte safeea ett F 4. Art aa oa aaele at safeerct et & aie vate sequfeeet stat Ft You have created a fusion between the mp ‘operon, which encodes the enzymes. for tryptophan biosynthesis, under the regulatory control of the Jac operator.. Under which of the following conditions will tryptophan 16 54, 5 & 55. synthase be induced in the strain that carries tho chimerio oporator fused operons? 1, Only whieh both ladtose and glucose are absent. 2. Only when both lactose and glucose are present. 3. Only when lactose ig'absent and glucose is present. 4. Only when lactose is present and'glucose is absent, cate «cnret fer aaa” (lave Save) A forear a a Fase” Sher at aifsrarettargor fra, are 7, 1. Lariat argeratsiver aia farts | 2. Lariat argraisiter -1-. arafergiors ara siifeesor | 3, temtfeect | 4, cifentcegeetsr | 7 Which of the following genes was engineered in the “Flave Save" transgenic tomato vari se z 28 a5 s 78. =e See £34 5: synthase, . I-Amino eyelopropae- ~carboxy! oxidase, PPE . Expansin, ' . Polygalacturonase, fara A a stad soars war goat aT pH sty Raqye- TIE, eaTSe,, CHAT, x AY ere 55. 4. argeratar vd argent | 2. ugerater ud aigetatigen ar screw ‘Feareet | 3. aigchater Ud Usha | 4. aigeraigars srertt wd afer ‘fereeet | Which of the following pairs of subcellular ‘compartments is likely to have same pH and electrolyte composition? 1. Cytosol and lysosomes. 2. Cytosol and mitochondrial inter membrane space. Cytosol and endosome. 4, Mitochondrial matrix and inter membrane space. 56. wet fears & Her wT se famaqeraet & dest A fret A a alae Beak waa Soya eT? 1. ach waraaer Fi, wa ae ferftier eter & sata, agate yenafead, carers FRE oe ef Pagerhtga at a 2.apt wage A, wa ay fata et & swia, aweicen yenafead, water RAT oe ef agerhigat ee EI 3. aigeclat yererfeat waa aa at arena fat ox agerhiga ett & cere saat fragerhrearer over a ‘oat BI 4, wigetclant qerafcant ace ROTA FRU aie ger cea at agora at ¢ ak aera Saar Frage eat t1 56. Regarding microtubule assembly _and disassembly during cell division, which will be the most appropriate answer? . 1. Once formed, kinetochore microtubiles depolymerize at the plus ends throughout mitosis. 2. Once formed, kinetochore microtubules polymerize at the plus ends throughout mitosis. 3. Kinetochore microtubules polymerize at their plus ends up to anaphase, at which point they begin to depolymerize. 4, Kinetochore microtubules polymerize at their minus ends up to cytokinesis, at which point they depolymerize, ‘S/46 BJ13-3BH—2A 17 87. e% oferat A venrer-zigeraofh | areer Hoe (PCR) aH H Ava, Portesess Suptehe (G3P) & wa sy SeTeet fae sot qeaareit & fart a a fre wer abort Ht raver act &: 1. 9NADPH 3 6 ATP 2. 3 NADPH 3it 9 ATP 3. 2NADPH 34% 3 ATP 4. 6 NADPH 3it 9 ATP 57. During photosynthetic carbon reduction cycle in green leaves, net production of one molecule of glyceraldehyde 3-phosphate requires one of the following combinations of energy equivalents: 1. 9NADPH and 6 ATP. 2. 3 NADPH and 9 ATP. 3. 2NADPH and 3 ATP, 4, 6NADPH and 9 ATP. 58. afc a searet A ore: Faegrret et & 1. GC age sepRA | 2. dat aT Ud GC age saFA | 3. areprat ar aig fafse facet at | 4. AT AGS 3ehH | 58. Origin of replication usually contains 1. GC rich sequences. 2. both AT and GC rich sequences. 3. no particular stretch of sequences. 4, AT rich sequences. somerrarrs «oF sffeasita decker wpEKS TAMA (oxidative pentose phosphate pathway ) @Y syfdter a aaah a et # OB ala wut wet ae 8? 1oarariaa sfafransit a dart a fee NADPH #1 3eUeet siraewear ee & Qa set a vetwr a far deca Glee seoreat sraeern gar & 3. quer afte arr a saeiedwor bq Qusyler 4niehe wr aera Ha SF 4, ATP & faator a fee NADH aT Beueat gra F 59. Which one of the following statements is INCORRECT about the role of oxidative pentose phosphate pathway in plant metabolism? 1, Generation of NADPH required to drive biosynthetic reactions. Production of pentose phosphate for the synthesis of nucleic acids, Formation of erythrose 4-phosphate for biosynthesis of aromatic amino acids. Production of NADH to generate ATP. 60, ser Trent a freweret BPs Uorget wre fara 4 @ steer anaes yeahs wae 8 1, farfaret (Nickel) 2. alferederat (Molybdenum) 3, feta (Zinc) 4. BTA (Capp) 60. Which one of the following essential micronutrients is assoclated with urease enzyme found in higher plants? 1, Nickel. 2. Molybdenum. 3, Zine, 4, Copper. 61. HOt A, ds ca Pere siete ite ert aera ot wenrer AY wea ERT aT ie carr ware et sre BL wearer vera ft core ff efte oft Aa aptaar wert Wee BP 2 3. 4, 1. dt & aren as A waar worst ee ae . aiReTRe (Cytoplasmic cGMP ) AGT IS TAM . oat & sat as A alsa yore ae a ond & . Heratieear Y onsHoT faetferer a sare & 61. In the dark, rods show a large inward “dark” current which is suppressed by a flash of light. Which one of the following statements, cxplaining the effect of light, is true? 1. Sodium channels in the outer segment of rods are closed. Cytoplasmic increases. Sodium channels in the inner segment of rods are closed. Transducin dissociates from beta-arrestin. 2, GMP concentration 3 4 2.7m, vee aT ree fate varemnfgal, ser arqwargt ott & ean aaa EL sitter Aifare fr feet A a ater ‘eh otter wenrer araprer & tire amet 87 1, PIF3. 2. NPRI, 3, PHYE. 4. CRY3. 62, Plants -are able to perceive light through various photoreceptors and downstream genes. Which one of the following genes is NOT involved in light perception? 1, PIF3, 63, FET BT TeTEeT (mast cell generation) & fee arava arta & fore UR ANH BART, 1L-3-FIH, OM CSE, G-csr-agt sty wagwtgiersya, FT eau Rar mer 8) sfret Afore ay ‘8/46 BJ/13-3BH—2B 63. 64. 64, 65. fea ase A Aeqa ater scored wager dat A aera wae afte 7 1. IL3-FT I 2. GM-CSE-7T | 3. G-CSF-AaF | 4, tagetagderaaet | Four groups of mice were studied for the factor required for mast cell generation: IL-3- deficient, GM-CSF-deficient, G-CSF- deficient and erythropoietin-deficient. In which mice, mast cell generation is most likely to be deficient? L.IL-3-deficient 2.GM-CSF-deficient. 3.G-CSF-deficient. 4,Erythropoietin-deficient. wa wa & preg fear & aeahe anager arf ot ofa ar mat at Reet He F RY ST AeA aT agt oRtafeta eral Sea ACT eure | . Garett | TeTraeT | 4. SIaRA | ‘A chromosome aberration leads to change in the order of genes in a genetic map but does not alter its linkage group. This is due to | translocation, 2.recombination, 3.transposition, 4.inversion, afe fret anita crfferaner (Graafian follicle ) # efter greet wtfeard (theca interna cells) ATCT et STE at GOTT rr ea? 1. aa edais-fis ar Frater | 2, afar alent A ar gr Ststeetiet GeTTOT | ens 19 3. arena west A wer BT degra BeetwTr | 4. vacrardt fis ar ferater | 65. What would be the outcome if the theca interna cells were destroyed in a Graafian follicle? 1 Immediate formation of corpus albicans. 2.Increased progesterone synthesis in the granulosa cells. 3.Decreased estrogen granulosa cells. 4,Formation of corpus hemorrhagicum. synthesis in the 66, Ree A, ore SOR ae aT Hen wae oft A quar a Het after gar 81 fier ste & ge ae ge Brae FY ret BACT HAH. HT HOT F 1, area sfx atari Fr worst Fr ag gS RTT | 2. cetsat A eer ga oeeRTH are | 3. ort VOR ast A ag BT weet are | 4. are Bae athena A are doe whetat ar feats | 66. The size of red blood cells (RBC) in venous blood is greater than that of arterial blood. This increased size of red blood cell in the venous blood is due to I.the increased permeability of red blood cell (RBC) membrane. 2.the decreased osmotic pressure in plasma. 3.the increased osmotic pressure in RBC. 4.the dissociation of cytoskeletal proteins in RBC. 67, AR FT (Seymour Benzer) A Lert (recon) AY sreereor wreaTfeeT ar eft 1, haropiish T4 a saat seahtafedat & ate Grafs ar Herat aS | PSE] 1 vsthi BIRGIT v0 FIR: i "0 ea Gere ga ' ; we et htolal = 1 A TEAR FARA Hh sais} oN i, teen Rasa ablong Vow 67, ‘The concept of recon was proposed by ve (Seymour Benzer ‘by.istudying: kecombination temp «ysis mitant’ bf backesidphage TE: whitey “eye tvitnbitantsi(si0f WDrOsophila melanogaster... 3. ‘biochemical’ mutants sslerassai\ oy oT 4, auxotrophic mutants of Escherlehla coli. 68. eS | (giterenalty ta pera! aera 8) gaan ara gee sit halt et area wa ata & siete meat 8, qeeehforal vol pb Sher seater: san! arama ugar 1 teh ieee oi feat a ata nth atts Fay Sar o bord STL oT bd 1. reat aa vig 2 boold 2. MHC APT atheros ont elt eMac Ub ata py A 2 ate | ] of Netirspora thai 68, One aims to fihd dif the role of gene product “in nacrophages by using a transgenié mouse expressing the genes under a promoter. Which of the following is the, most sport WD (oor) mitotic: 4 Th: promoter: 4 waelivey Tits “i goltexatog Moo sestt sist doirter 69, The speciation “:whicho'a population splits into two geographically :isolated’.populations experience. dissimilar:seleetive> pressre and genetic drift is knownias 1. sympatric speciation. 2. parapatric speciation. 3. yperipatric speciation, 4 ‘allopatie speciation. its ics 11» get er, Rare ghee wae Aer otter REPT SAM Ie ths 2. Fra server shar-faferRy ART, 3. anette SeuRactell AITisky 4. tet otter aferyeray ean ‘Sth faferrr gant | #170. Evolution of multi-gene family cers: by 8 eoob ds fly. gene duplication. 2) Oly iitequal ‘crossing:o' 3. random mutations. #0! Sty Tes ehi6e nip ney st_“aT'/PART 'C' 11. sari apie set sit westciiss & frost ovat & & atarar wee? 1.*Ormithine aspartat. tryptophan -quinine’ 2.‘Omithine-nicotine’and ‘tyrosine-orphine” 3.‘Tyrosine-quinine’ and ‘tryptophan- orphine’ 4.‘Omnithine-quinine’ and ‘ornithine aspartate - nicotine” ine’and, 71. Which one of the following pairs of precursor amino acid and alkaloid is correct? 1.Omithine aspartate-nicotine’and tryptophan -quinine™ 2.'Omithine-nicotine’and ‘tyrosine-orphine” ” and “tryptophan- nine’ and ‘ornithine aspartate - nicotine” mn. wR at ee wd sie afar, aes wd sais, gant ser (apoptosis) eqra at F 1 aeT war ater aes fetes & ater wae aRq aitat & ance cant aime gat Sl sae fate aa aS senda saver stake oer at air azar 3 at wre-srerdt are wd aren wietet afar 31 feet ater A A yer dato cant igelata C mt wfaee arrar war 8, saa feat ater BA, weit qearietor gant urgeletr C at at vfase aera war &, Wey ae wa aH ( wteteit ) 21 2B. HOO Yoo Cells undergo apoptosis by two distinet and inter-connected pathways: extrinsic and intrinsic, Extrinsic pathway is activated by extracellular ligand binding to cell surface death receptors. Whenever an apoptotic stimulus activates intrinsic pathway, the pro- apoptotic Bax and Bak proteins become activated and induce the release of cytochrome C from mitochondria leading to caspase cascade activation resulting in apoptosis. In cell A, cytochrome C is introduced by microinjection whereas in cell B, cytochrome C is introduced by microinjection but Bax and Bak are inactivated. What will be the most appropriate apoptotic response type in both cells? ML ‘og fl | BALBle Hyat &r gist wa (DC) @Y 1L-10 3iaT IFN-Y @aRT Soe spoptnte 1 fever aren get SATE pa-TIgMITAteA fer iter art fr afar a Rresit a aft IL-10 3tYar IFN-Y ERT seater Pear wear | gat aR FLHEL tergs Fr safeaiet a, apit a sist & order (HEL)-Paftse tT aafterarér oerefetr aye & cps 7 atftensit a wer ae. waftia fer wer | vie at a are, cps" T aiftrenrait ar eden aifererr atztet & fore sree fear aren | sft AST fe fer dateit a a whet a afdeert ede after snfastaar ete 1, DC (BALB/c)!"“"°x CD8°T 2. DC (BALB/c) "x CD8'T . 3. DC (f2-microglobulin-deficient) Meloy. cps'T 4. DC (2-microglobulin-deficient) "x cD8'T 73. Dendritic cells (DC) from BALB/c mice were treated with 1L-10 or with IFN-Y. Similarly, dendritic cells from 2-microglobulin- deficient mice were also treated with 1L-10 or with IFN-Y.These cells were co-cultured with CD8* T cells from hen egg lysozyme (HEL)-specific T cell receptor transgenic mice in presence of the HEL peptide. Five days later, CD8" T cells were assayed for target cell lysis. Which one of the following combinations will have the highest target cytotoxicity? 1, DC (BALB/c)"“°x CD8°T. 2. DC (BALB/c) "** CD8"T 3. DC (B2-microglobulin-deficient) "“"°x cps'T 4. DC (B2-microglobulin-deficient) ""* cps'T 14, Wh Bet Tift S. Be. BL Tet -seroy-swe Se wes aT MT - BB(liquid nutrient broth) A gfe ase At crerforas STE (Rea area —> afar sree > eanht sre — IY sre) eee Safe wna wearer 10° wife fAfer art saropsit a waeier ar ceTar WAR 10 fare et Se Sa Vote TART aft 10 fare @, at efter Afr fr 30 fRae oot ser oe wT weeaT areal (Re afe) sete 1. 6.0 x 10° 2.2.0 x 10° 3. 3.0 x 10° 4.4.0 x 10° 74. A rapidly growing bacterial species such as E. coli exhibits a typical phase of growth cycle in liquid nutrient broth (lag phase —> log phase —» stationary phase ~> death phase). If a bacterial culture has. a starting density of 10° cells/ml’ has a lag time of 10 minutes and a generation time of 10 minutes, what will the cell density be at (cells/ml) 30 minutes? 1. 6.0.x 10° 2, 20x 10° 3. 3.0x 10° 4, 4.0x 10° 5, we at ara afte eo, wa sis aT fiat ad & at aga (polyspermy) fr, feufat seat eter 21 UE WE: oer ett & safes Te wT arrest ar sere art & fret fet wp dear sik we feet Be 1 ge eae & ofeter A aga safest A agepryeT at arate face aa &: ga arate ait ag sente Bay sift A: (A) 9 state ar wera acaret lat & ferry creat & sie py aT oss aT Wafta ag get at cer we fra aban saat & siacig carr ware # ont e | (B) OF HeRte ar vera aearet erat & fore waraET FS HoT HT ACT faa ae creat § HR eT aT is arr Watts al get tat ae ag fer aifanr area a afkate gare wera Br ore & 1 (C) Feq aeRler srrat aepe | witTaT sara afer | aell zane waratfert Fr orat & 1 (D) Fee HANG sera aoe Hira HARA eRe saat gant waraAfera Fr oredr €1 sMied AS was Het wea F 2 1.(A) RO 2.(A) 3 (D) 3.(B) HK] 4. (B) 3i& (D) 75. Polyspermy results when two or more sperms: fertilize an egg. It is usually lethal since it results in blastomeres with different numbers and types of chromosomes. Many species therefore, have two blocks to polyspermy: the fast block and the slow block. In the case of sea urchins: (A) the fast block is immediate and causes the egg membrane resting potential to rise which does not allow the sperm to fuse with the egg and is mediated by an influx of sodium ions. (B) the fast block is immediate and causes the egg membrane resting potential to e which does not allow the sperm to fuse with the egg and is mediated by an efflux of sodium ions. (C) the slow block or cortical granule reaction is mediated by caleium ions. 23 (D) the slow block or cortical granule reaction is mediated by potassium ions. Which of the above statements are true? 1. (A) and (C) 2. (A) and (D) 3. (B) and (C) 4. (B) and (D) Toomer osretrr ate afr seperott & Gres Babe oRRaOT ae A ag chet & wea eet & fare soar fee ona @ 1 sia Hifae fH eat a a alae sramith vce daa ofait at daa & aa & fae soar & at as a 1. aeiiee A weer A gfe at ROT deft TeTRAT 2. weir Raya aera Wear A ach sree 3. afte A aOR A ga wed & aT weft siren 4. wer ofeeat Fr arerhr 76, Typical morphological defects are routinely used in genetic screens to identify novel genes in signal transduction pathways. Which one of the following morphology has been used to decipher the ethylene signaling pathways? 1. Light grown morphology of seedling. 2. Triple response morphology of seedling. 3. Dark grown morphology of seedling. 4. Morphology of true leaves, 71, svat Sel HepRHOT Her OX are tT we wept ofate often A aeansit & uel Hea ar oer AST 1. Shea v Prenursadas grant Frrattor> separator > ASSO BATT Sfecactarcrstada a regia 2. 8. BY er. atwarntor > greenery rator > arapiveror > asiateor Ss Reed ator Dat ahaa a mEgiaaoT | S vat v fava ada> ARTE ‘Geter >. Gereret ART: se Foes ‘ CY hn aia . Choose the correct sequence of event in a next generation sequencing techitology/ based 4 whole genome sequencing project. LDNA’éktractidnt shearing —itbrty Ne preparation —+ sequencing assembly finishing —» qnnotation —> submission te, Genbatik, 2.DNA extraction’ library preparation =>! sequencing —> assembly ~> annotation» finishing» submission to Genbank. 3.DNA extraction — shearing “+ adaptor (° ligation —» library amplification»... sequencing —» assembly — finishing > annotation — submission to Genbank, 4.DNA extraction => adapter ligation“ tibia 4 atnplification - shearing —> se = finishing — aisémbly — aniitatio sulpmission to Ghani: “ali isxiq we watt a, 3A, AM erie eae: gherhorgor iat “cists: ‘evga is aot ir, eet" hare Be 2, & Ratha we Rear sar ate gee He at after Be ahh A ce Ra ata feaias yaar waren as ofan BY wear A Shear peter arewran sere” oy, Siar ARTE fr faa he ate resist aagifeeatite eaaRent losin ier aiitransit A after vadt aire watt @ afther! Siar gfe: aw RRrerait gerber ast Saray SisRUT TTA arena cor Ay Fai feta aa & ee Brean etre 1 3 Wik eta) aiRreri ae Reon eneiiReer Sat apbfttear Gi ate: sh afferent eager ae pt ore ar feator ats Oa aad areiatateor a aeaaa agomiRreratiess aerial smretette AR sa wat a Raita) ehae eifrar sin Farin aptety HIBIE BIpBIE Oita were sree cian ARIA wferag vad at ware Tact & aie va fafeatett etre ay fenton &q ‘aRaftier: @t ores fora fameeer eta até effet! aor tome rat PBF gear a aan UR TION a wo a aid ee (9) Se (ay & uy 18 Manic (cy vtie . In an experiment, the cells that would normally become the, middie, Drosophila leg. were, remoyed, fom, the foiming area of the larva and were, ie in, the tip of the, fly’s antenna, fas foi a “French flag” analogy forthe, operat gradient of positional “nemo ‘ash eo the following. statémenits is true? appa i from, t canary net vay otk at The transplanted cells retain their committed 180 mac spspend ito, be «1. oa ete ac gino 0 becoiing hn gain The’ transplant red ae ie aa eel Ine ant mined as /es omplets oly (£1) ele wath ynment,and Jimb instead of an antenna, ;* The transplanted cells would f inierm the cells present in the, new enyirot cen accordingly, to, ante ‘voi cl sui io dvold wole ott (7 wi nyuiolss ed bolsibara ai noise vue 4, The transplanted cells retain their committed status as leg cells and would develop to form a chimeric structure having proximal region made of antenna and the distal region ending in a complete leg, 79. wren a are venrer apr areraterer 1. after ander sri axar & sik Wha gaat at aR aa t 2a dia afMRa axa & sik tha ged at sata aa & 3. wha gaat at setts aa g 4, wien ater ar sender erat & 79, Perception of blue light in plants causes 1 inhibition of cell elongation and stimulation of stomatal opening. 2. stimulation of cell elongation and_ inhibition of stomatal opening. 3. inhibition of stomatal opening. 4. inhibition of cell elongation. 25 80. Protoplast fusion is used in plant tissue culture for various applications. In protoplast fusion: (A) -naked plant cells are used. transfer of organelles is not possible. partial genome transfer is involved. cells from two different plants can be mixed together and forced to fuse. Which one of the following combinations of the above statements is correct? 1. (A), (B) and (C) 2. (A), (©)and (D) 3. (A),(B) and (D) 4. (B),(C)and(D) a. ag A out sik sae agH saeait A daca fre are fart tor gata & aro fet (A-D) A A we oftoray feranrest? amferta att | ater at aa saH 80. Ter Saw Batis A shagern doe fafar sq A soahr feet ora @1 write age SHageas deer A: ((1)| sar ardt aeaerear | aeaera (A) aver orem aifRreare weer Ht oaret BI aaatfreare (B) sae Fr SaaiaT Besa aE BI (2) sat arezceren | srrt aaenifrenre [ase raTe (© sites shatter eeretieaeor weaet eta 81 San gH Oe Beater oat & atest ae Gla lad wear Palit array frome deat & fac fear aanifieac far aT weeT BI (2) std areacaen | set aaatfrare| areacre sia Ase fe sated weet ar fret - FS ater dato wet a? (A) oR aE dge Fr aire 1. (A) (B) IR © aufeder oRatia cate & 2. (A), © at DO) (8) wnRe aE age Hf ware 3. (A), (B) 3k (@) Fated Rater aetefr & 4 - (B) (C) HR O) (© san AE age & atte aufeder Ratt cetct & 26 (D) Bae Fae age Fr aire 82. varrest oftatier ae & agt oRomet & 1.(A) ait (D) 2.(B) 3k © 3.(A) Alt 4,(D) at 81. Which of the inferences (A-D) given below would you draw from the following tissue transplantation experiments performed with the early and late gastrula stages of the newt? Host regions [Donor Differenti regions ation of donor | tissue EARLY GASTRULA| (j) | Prospective neurons [Prospective [Epidermis _ kpidermis ii) | Prospective [Prospective | Neurons epidermis neurons ILATE GASTRULA (i) | Prospective neurons [Prospective | Neurons | 82. pidermis Gi) | Prospective irospective [Epidermis epidermis yeurons (A) Cells of carly newt gastrula exhibit conditional development. (B) Cells of early newt gastrula exhibit autonomous development. (©) Calls of late newt gastrula exhibit conditional development. (D) Cells of late. gastrula exhibit autonomous development. ‘The correct inferences are: 1, (A)and (D) 2. B)and (C) 3. (A)only 4, D)only sreivear # vidharat sft cer wight (Ran, par ent ate ws yaa) F sat scaftacdt carormmedh a srepHe Fasnfsre ete 1 ant Ge way wishsraet ted verdt oat at oan dre (Bag % Hest A) weqa PR ara @: “ @) hairy -> paired-> tailless > patched hunchback > even-skipped —> fushi tarazu -> wingless (© odd-skipped —> giam > paired > wingless (D) tailless > hairy —> fushi tarazu > gooseberry ‘Sint Hifoe fr urea BY seat aor a aitearat stat & aoe few aepeat A B wearer a wer F 2 1.) art 2.(A) aie (B) 3. (©) ait () 4.(B) ait ©) Segmentation genes in Drosophila are divided into three groups (gap, pair rule and segment polarity) based on their mutant phenotype. Below are some of the major genes expressed in a sequential manner (with respect to the groups) affecting segmentation pattern, (A) @) hairy -> paired» tailless > patched hunchback > even-skipped —> fushi tarazu ~> wingless odd-skipped —> giant -> paired — wingless tailless > hairy —> fushi tarazu > gooseberry © () Which of the above sequence(s) of genes expressed from early to late embryo is/are correct? 1. (D) only 2. (A) and (B) 3.(C)and (B) 4,(B) and (D) 83. Tent A crea oRatr & Her (A) ae IR St qe aired aka a SRid at wah fasnoet gant scot art @1 (B) rT 4 aware ata ater oer oRacian H agree ett @1 (© sfayat aiftare oak aor ar ara wart eft EI (D) wrraferar we ont Fos aat ae apaat at wn arqaita agate (synergid )% Haare et B Sr feu ae aeat Aa strat aes? 1. (A) 3 (@) 2 @) 3k () 3. @) 3k © 4, (A) 3k (D) 83. During reproductive development in plants: (A) male and female gametes are produced as a result of two mitotic divisions after meiosis. (B) vegetative cells in pollen contribute to pollen development. (©) antipodals provide nourishment to developing embryos. (D) pollen tube ruptures and releases both the male gametes in one of the degenerated synergids. Which of the above statements are true? (A) and (B) (B) and (D) (B) and (C) (A) and (D) BYERS 27 |. Sareea H feta & Hea epHOT-3is aieahes Bran, ster defer (zp) war Ft wera 3 Serhr esoror aor A faquaret afgat gant waited Fr ont 81 zP3 tat wy zp sider seu at age fore Tea-stefariees SALT epPHTT-HS aeterfrar & fae Ageapt 81 wae sioedarers sree sia A epee Fr pRUp-sis eater fear srerrt A ye, 2P3 Heal FAH Baia wat A AT ax fear war & 1 sitet Aifere fee fae a8 aae i gers We fem at sreatftr at ater seer & os eperoy a zp3 sda B aged ay afar ZP3 Wier ar favergHsaeedt at a SMa Saal YR] AyrA aa H fae saetr Arfsre 2P3 Wier aT wren at SRlt SAH YY Bat ae a fae srarr AST 4, ZP3 wider ar fantenicter at SRid saat PMY HT Se & fae srart HAST . During fertilization in mammals, sperm-egg interaction is mediated by zona pellucida (ZP) membrane proteins and their receptors present in sperm membrane. ZP3 has been identified to be the principle ZP protein whose post-translational modification is i ~ egg interaction. In a ibition assay the sperm is saturated with either active ZP3 or its modified forms, before studying sperm-ege- interaction. Which of the following experiments will. NOT inhibit sperm-ege- interaction aR 1 Saturate sperm with ZP3 protein prior to use. 2. Deglyeosylate'the ZP3 jprotein bind Wi8e"iN tor! saturation of sperm... 3. Phosphorylate th satlitation! of sper. 1°" 4. Daphosphorylatgzthe. RB poteiniand tuse)its for saturation of sperm.. Bogs, ETA ahh, soorenfeaiehh: srorary Fb atteetsret aoe sae Soe oT A vies Gis \ ag Meme eERMOT. AT ag URE VaR! AS WareawT Sey ae Have HG Sar | Be ScaRactar ar Tereraietaer ariet! aie wat! qf aemginaral sétieterlive «I varersrardt aft a weeds ag het! Geir Sta-se: zeit kw To SK Beare: a seer cia ao teRaETT vfeerat ‘aor ar sftomay spore et Sates . If an Arabidopsis plant, mutated in eens biosyinthetic™ pathway” is “grown In” sunny’ tropical climate in the presence of dxyigei 86. Would adéithtile highée Bion :f higher ratelofiphotosynthesis: 2. there will not be any inf mutation on the rate of phot eaagcit and plant growth. 87. 3.""it'woilld: show'"Feduded Biota aie CJ * ‘dati pois ai toitamiolal ) lait ue (A). MRT saath wer A, water aga! oiforteIH (B) afield arratt (RY TERAE, BE, 5): remgaiterangte) er safeaferhin 1 (© her vier (D) RRA ATR Mama eatin ah ae pine ae cs, este Tee yiie yes ae ye a; ma is Hove gy Te Riese 3. (0 4 @ faeéte wR oe att © Ghee ras pip Accord to’the clirént’model offaitetfiative” oxides seat he afilloving Aes Ti 2) (A) ‘signifigantsineréase if the, ubiquitisipgote in the cytosol. presence of a-keto acidé'tiiké Pyrite -! and glyoxylate). 1d) Wie) cold stress, sft increase in cytosolic ATE edndelitralioh. E (Al Which one of the following combinations of aboye statements is tue? aviiguboiqen guiwel 2 oy D hyet 7 ks si baw aleit (A) 2, ADAG). siren oi Yo sues 6 3." (A) and (B) 4a MaMlQaction ni T (hCG), oer RFE a Blh@G Sn FEAR HA PMA AT A: NOG Baw Rraifor gar ox aft sintat Hse § aml wa we ware afar 4, raters, a hCG ar sferet-saretia ax fear’ ara, at Sion arent Ter ae setae fa arerat a amtoor & fev: 87. 88. stew wo A afer amor ae ET hCG & anaverrar at ett coreeleec afer hCG HT SHE BT ura 3, st eae wo a ashe Porat A uerars eat o1 asa fr wars at asters AY sie saree & fae hco 4 araeawet wet at FI apr & aia & Hava aa & far afatted soir sae scaterht aét a1 Human chor ic gonadotropin (hCG) is known to facilitate attachment of blastocyst to uterus, In women with mutation in hCG gene, biologically inactive hCG was formed but implantation occurred. When hCG was immuno-neutralized in the uterus of normal woman, implantation failed. This suggests that for implantation in humans: 1 biologically active circulating hCG is not required. 2. blastocyst can produce the required hCG, which helps locally in uterine attachment. 3. trophoblastic cells do not require hCG for the invasion of uterus. 4, extra-embryonic tissue is not responsible for the attachment of embryo to uterus . Borer saat A sour decker wiehe oer aaet (savifaat a) age. TR & fae area qeaat a saaer aart & 1 aoe at War} Be fer FS ata wert at era? 1. NH! @ RARE TAC Hae a geiioae A eraiaa et ‘Sat @1 2. amteragte aitarcer a waviiras A carafe a stat g1 29 88, (A) (B) © (D) PENS 3. aapreoniere = avira A aitarcea A enatata e star & ait arr eat F | 4.gmm owiehe | aire a sravfferrs A Renata eT Ta él The oxidative pentose phosphate pathway provides the reducing equivalents for nitrite reduction in plastids (leucoplasts) of non- green tissues. Which one of the following statements would be correct for the above mentioned pathway? 1. Glutamate synthesized from NH,’ is translocated from cytosol to leucoplast. 2. arketoglutarate is translocated from cytosol to leucoplast. 3. Glucose-6-phosphate is translocated and moves from leucoplast to cytosol. 4, Triose phosphate is translocated from cytosol to leucoplast. Wer & aot fase & Hast A Ho weet aire few are &: Fer set aT RRO faare (y,) aah Fenit & faa aes: awa ear él wach Fer ar TRO fase (y,) Fat ea & afte gar a1 ype Feat A aeT oe fara a xa eafaw ara (y,) Hear carers stat B1 Her et wT TTpedter Fast (y,) HAA GE & Sag & arqaige ear 8 swiea seat a fet A A alee Patort BET F? (A) a © (8) 3 © 3k B) (D) 3k (A) 89. Following are fow statements regarding water potential of soil. (A) The osmotic potential (y,) of soil water is generally negligible, except in saline soils. (B) The osmotic potential (y,).of saline soil is always more than zero. (©) In dry soils the hydrostatic pressure (¥y,) of soil water potential is always positive. (D) Gravitational potential (y,) of soil water is always proportional to height of the tree. Which one of the following combinations of above statements is true? 1. (Ayand ©) 2. (B)and(D) 3, C)and(B) 4, (D)and(A) 90, after vise a, caer afer ater sort der gait a fer vitae ete ee wee at gat areeT-arorT ser gait Fr ated at af ad Brera (aG-CSF), afPraTUp-qETHTSH watetet aR aR (GM-CSF) tt aftr, arrar agasitshartetetr HABA FIA (G-CSF HAT M-CSF), BI WH GM-CSP-ayat asa a, draretstetear wir fr deer a afar at saree Siar Aafore fas reat AS aah a Bet &? tome afart A deat at ares Watt Aer aor ote qpasnisrat #1 sear we ores. 2, efter act at weer Reet, Arar exert Ar ae 3. apawtety fr Hear srahateet waht. 4, ayer Bat ater wee AY atferatt & wager aur | 30 90. In bone marrow, stem cells-are committed to different lincages. Factors that stimulate the colonies of these different lineages are interleukin-3(multi-CSF), —_granulocyte- macrophage colony stimulating factor (GM- CSF) and granulocyte or macrophage colony stimulating factor (G-CSF or M-CSF). In a mouse deficient in GM-CSF, the number of hematopoietic cells will be altered. - Which one of the following is correct?” «Mast cells will be normal in number while granulocytes and macrophages willbe deficient in number. 2,Granulocytes count will be normal but not of, macrophages. 3. Macrophage number will remain unaltered. 4.Mice will be deficient in all the three cell types. o1. Bg cafe oat wath venfat wisa aml wert SB sat wer fe ae froteiger soviat att err fire ge BI wa oad order A ag at see faa (wetret) A ate ore are: (A) Serr aeapraar TRE are finer wher (B) FapRrT aReargar steer (C) Na‘/K* ATPase . (D) CoP ATPase j aAfae Pe ga wee A ore aigag & fore sates a A aher-aT BOT Br amet 8” 1. FIA (A) 2. (B) ak © 3. (© 3k (D) 4. Art (D) 91, An individual was suffering from digestive complications. It was observed that the individual had dehydrated gastrointestinal tract, When an advanced investigation was done, the person was found to have defects in the following: (A) cystic fibrosis transmembrane conductance regulator protein. (B) glucose transporter protein, (C) Na'/K’ ATPase. (D) Ca* ATPase. Which of the above could be the cause for such a digestive disorder? 1. (A) only 2. (B) and (C) 3. ©) and (D) 4. (D) only 92. a) WER a gat SY Bays srr I BAT wae oa Barer gat wre ae atest Fangs GaN Scat t aaTe TAM war afer ear raat ar ag fart oT, agate ae owe feras & ater dite oa aitaiaer frarefrer fasra afte fre are) ae oar wer fi atat Farecat A rar fara a opie areer-srerr eh sft afore f fet A awe wane aftorer ata-ar gta? 1 Wear arr seat faare A afar ag go or af wage A Pat aiBae igor aor fire Pere aT eet ae Ta et, 2, Tet erase a aan vig & weet & areare fear fae ar sey UR we war a, afer Har Bae # said ag as eh. 3. targa & fret ear Bigot a arr Aa Thor fsa ae war or atte Arar fasta er arava sit aa et ae aT, 4, Teaht carga A war igor & ue ort ow, fear fee aT eT 31 waRafeter ter em, fear fasta Fy arafer ae ag ef. 92.The action potential was recorded intracellularly from a squid giant axon bathed in two.types of fluid such as sea water and artificial sea water_-having lower concentration of sodium ions while maintaining the same osmotic pressure with choline chloride. The nature of action potential was different in the two bathing fluids. Which of the following results is most likely? - The resting transmembrane potential was not changed but the amplitude of action potential was increased with lower sodium concentration in the bathing fluid. 2.The amplitude of action potential was gradually decreased with reduction of, sodium concentration in bathing fluid but the duration of action potential was prolonged. 3.The resting transmembrane potential was decreased and the amplitude of action Potential was also decreased with lower sodium concentration in the bathing fluid. 4.The amplitude of action potential was not changed with reduction of sodium concentration in the bathing fluid but the duration of action potential was prolonged. 93, Arrat Howe aftaa weonga AY ope A 7S! Se TURE A oa at far fre ow Giga aT Reda AT are fet faeuarer &, fet faftat soar Bi (A) Vargas Fr Brareftear RNAi aafta a Src! (B) Seiwa + one Afar att seer deaf ar Heat at & fae aeract ar feeder Afar] (©) Varga ar giao Ais, geek achat SET Hep HT Tat aeTse, sa St var zart 32 gies Oe Bie 8 ve aieh 8.2 teen 1. Codeine Papaver somniforurt 1: +3 2. Vinblastine — Catharanthus raseus 3. Quinine — Cinchona ledgeriana 44) in the figures, above. 1. X; =-Geographic distance, Y; = Sexual isolation index; X, = Genetic distance, Y= mating frequency 2. X; = Geographic distance; Y, = mating frequency; X2 =" Genetic distance, Y, = Sexual isolation index 3. X= Genetic distance; Y; = mating frequency; X; = Sexual isolation index; Y2 = Geographic distance 4, X1= Genetic distance; Y; = Geographic distance; X; = Sexual isolation index; Y;= mating frequency 36 103. ferear at fret aah A are at der 103, 1. faeurener gt F 2 1, aeysrech, afr, etter 2, fercrch, aoa, wore 3, Sarenrong, fetch, werrerat 4, RETA, WoT, FETT Which of the following groups have only two wings? Honey bee, beetle, ant 2. Butterfly, housefly, fruitfly 3, Dragonfly, butterfly, fruitfly 4, Housefly, fruitfly, mosquito 104, 104, areca ara a stentogrer a, 2006 ( faear ae ), a atpene feat a B ahaa aAeitenfet (Nothospecies) 8? 1. Polypodium vulgare subsp. prionodes (Asch.) Rothm, 2, Polypogon monspeliensis (L.) Desf. 3. Agrostis stolonifera L. 4, Agrostis. stolonifera L. ‘monspeliensis (L..) Desf. x Polypogon As per the of International Code of Botanical Nomenclature, 2006 (Vienna Code), which of the following is a Nothospecies? 1. Polypodium vulgare’ subsp. . prionodes (Asch.) Rothm, 2. Polypogon monspeliensis (L.) Desf. 3. Agrostis stolonifera L. 4. Agrostis stolonifera L. ‘monspeliensis (L..) Desf. x Polypogon 105, fare ay Aeegs RRareRt ar soar terest ar afsrerar ar freien axet a fee fer ore & aie aed fer ae aes Hirata Pee ae e: ‘ero Kw(mM) | Kea") PAPAIG | 402 26 PAPAtA | 151 etl PAPA IF | 0.64 Z are aaa cua at sa ara g1 ST fare ge ero & er seta tar & A (Ay PAPAR waif ga afer & orfeer Bat BI PAPAG walftles get afer & onfeat Bar eI CRT we Hepa sere waftse srpeitiee fear stat 81 CARRE oe war STATE aT srafttee arapbfear rar ren & 1 wareeat # Paget Bret N-RGT WR dd wa aanpa ay sae ht arava eet F 1 @) © (D) () Sia Pifare fe fret FS aha Be & (A), ©) ) (B), (D), (E) (at (©), E)art Reyer 105, The following small peptide substrates are used for determining elastase activity and the following data have been recorded, Substrate [Ky(mM) | kaa(s") PAPAIG | 402 26 PAPAIA | 151 By PAPA IF | 0.64 i The arrow indicates the cleavage site. From the above observations, it appears that: 37 (A) PAPAF is digested most rapidly. (B) PAPAG is digested most rapidly. (©) A hydrophobic residue at the C- terminus seems to be favored. (D) A smaller residue at the C-terminus seems to be favored. (E) Elastase always requires a smaller residue at the N-terminus of the cleavage site. Which of the following is true? 1. (A) (©), 2. (B), (D), (E) 3. (E) only 4. (D), (E) only 106. aRa H adaret H 17 Sais fra gs ot Rerier oat a viata we @) ue mer as, ae Wem Bat dat a aia ot A fies &1 Sadsa fear A srauor Fr ‘wafecet corear ater arch wetat (A a G ) & a8 dae & eae Afar. (A) Bearer, (B) fer, Carrdrr frarr Bee, (D) Frade fant sep Ay, (E) weraeret faites wala, (F) aS wares feraar él, (G)eiter. 1.(A), (B), (©), (F), (G) 2.(A), (B), (D), (F), (G) 3.(A), (B), ©), (E), G@) 4.(A), (D), (E), (G) 106. India has currently 17 biosphere reserves representing different ecosystems. These conservation areas significantly differ from the conventional protected areas of the country. Identify the correct combination of attributes (A to G) that best explains the concept of biosphere reserve. (A) Conservation, (B) Education, (©) Human habitation allowed, (D) Human habitation not allowed, (B) Strong legal back-up, @ F) No supporting act, (G) Research, 1 2. 3. 4. 107. af il 107. Mews Hy (A), (B), (©), (), (G) (A), (B), (D), (F), (G) (A), (B), (C), (E), (G) (A), ©), ©), (G) Ae Peer uRat dae ‘omferat a fear araror atte Peon test few ae € 1 str Aire sent alacer onftet a siete afgeaeor ay STARE aR? ‘erat rao ‘trina rant Eo orca Envirohmienta gradient Followings are the niche characteristics of the constituent species and resource partitioning pattern in different ecosystems, Which of these would lead to competitive exclusion of species? ih aE * etrimary Production 38 108. achat srr Venfeter safer Hero 108, faafter a fr yer valet arora Ba 20.3rftee aerget oae wart aor & gare afavlt viegn, Beat & ww ar Ltr & aie agar art D-tenfet & darear B, ay 185-250 nm a att a aifafGer rar arm sitar Ae fe se fei a feat a & ata-ar Sar sre: wig vite at alfa etait aeergst a aaigelitearer aor fare et Set | ait aonene deigedterar & arr afeat: wai D-Ala Geergs & arr welt seshr area grit | am corer degederar & arr vfrat: wile dat @& tcegs afaoreitae ‘peterat ferator ater | wat ore rT atiqerar are afzal | The amino acid alanine has high propensity to occur in helical conformation. The circular dichroism spectrum of an equimolar mixture of two 20-residue peptides, one composed of only L-alanine and the other only D-alanine is recorded in the region of 185-250 nm. Which one of the following will be observed? 1. No signal: as the chiroptical properties of the two peptides will cancel 0 2. Bands with only negative ellipti helix formed by the D-Ala peptide will be unstable, 3. Bands with only positive ellipticity: as both the peptides will form right- handed helices, 4, Bands with identical Positive ellipticity, negative and 109, 109, frat siieertcergs 1 AS aaa aT fruor art & fav, ara qasTTEET (A) ZR, sitet ae Garoet wT ITET mem sraret Hifersiicergs at arateeiattesa (B), aageiightur (C), fefeeet (D) 3ik CNBr (E) &® arr arate far sar er sk Ba ES far sa see et Pee war an | sede are Seerget at feat Par arr am] fareer Roney wre Be (wIST wete ser A sate seat & aor aati 8): (A) (2Ala, Arg, Lys, Met, Phe, 2Ser) (B) (Ala, Arg, Lys, Met, Phe, 2Ser) and Ala (C) (Ala, Arg, Phe, Ser), (Ala, Lys, Met, Ser) (D) (Ala, Arg), (Lys, Phe, Ser), (Ala, Met, Ser) (E) (Ala, Arg, Lys, Met, Phe, Ser), (Ala, Ser) afta Ase fe alifaendcergs ar we wn Bes Ha ata oD 1. Arg-Ala-Ser-Lys-Met-Phe-Ser-Ala 2. Arg-Ala-Ser-Lys-Phe-Met-Ser-Ala 3. Ala-Arg-Ser-Phe-Lys-Met-Ser-Ala 4, Ala-Arg-Phe-Ser-Lys-Met-Ser-Ala In order to determine the primary structure of an octapeptide, amino acid composition was determined by acid hydrolysis (A). The intact oligopeptide was treated’ with carboxypeptidase (B), chymotrypsin (C), trypsin (D) and CNBr (E). The peptides were separated in each case and acid hydrolysis was carried out for B - E. Following results were obtained (the brackets represent mixtures of amino acids in each fragment): (A) (2Ala, Arg, Lys, Met, Phe, 2Ser) (B) (Ala, Arg, Lys, Met, Phe, 2Ser) and Ala (©) (Ala, Arg, Phe, Ser), (Ala, Lys, Met, Ser) 110. The apparent pH of a fluid is 39 (D) (Ala, Arg), (Lys, Phe, Ser), (Ala, Met, Ser) (B) (Ala, Arg, Lys, Met, Phe, Ser), (Ala, Ser) Which one is the correct sequence of the oligopeptide? 1. Arg-Ala-Ser-Lys-Met-Phe-Ser-Ala 2. Arg-Ala-Ser-Lys-Phe-Met-Ser-Ala 3. Ala-Arg-Ser-Phe-Lys-Met-Ser-Ala 4, Ala-Arg-Phe-Ser-Lys-Met-Ser-Ala 110. feet aa wT Memet pH 7.45%, wet se aare Tat A argarrefete aoe dae eat 1 aralfery srt pKa FET 6.15 ate 1o.4s @1 [agree (3r] aT Hee sea & 1. 1:20 2. 20:1 3. 1: 1000 4, 1000:1 ater, Ree 13-200, a oF 10" 1000) 7.45, where bicarbonate buffer is involved for maintaining its pH. Values of pKa of carbonic acid are 6.15 and 10.45. The molar ratio of [conjugate base] : [acid] is (Hint: antlog 1.3 = 20.0, and antilog 10° = 1000) Wi. Seeert & diet wat grit sania, aguarehiare atte agteraters at, far snfdaar agcare feat 8, agh aia wat A senrsremr dalfta fear vem! saegeat ft frederiat aT frater art & fee aires ferric A seegrett & sisel ar araraa fra arm weonfaer oRener Presta Vt wet & (A) amanpear oy carmentt Seaerit Ar fardeoiern, a8 drag A geen & wl anfOas er (®) sentir Saag, apherairs athe agearitrs Sragit & gear a wet arftien ferecifaer ge a (© agherifera Sera, sari ak aguariiran Seager quer A wet after freiieer gv (D) aguas = Seeger sarfet aihe agheriiaas Seagret A qe a art after farecifeer ge a1 Sita Afse fe fer a a wheter aielorat wer 8? 1, (A) ar 2. (B) HT 3. (A) 3 © 4. (B) ai (D) 111Three forms of dextrans namely neutral, polyanionic and polycationic having different molecular radii were injected separately in three groups of rats. ‘The concentrations of dextrans in glomerular filtrate were measured to determine the filterability of the dextrans. The possible outcomes could be as follows: (A) The dextrans having smaller diameter have greater filterability than larger dextrans, (B) Neutral dextrans were filtered more than polycationic and polyanionic dextrans. (C) Polycationic dextrans were filtered more than neutral and polyanionic dextrans, (D) Polyanionic dextrans were filtered more than neutral and polycationic dextrans, Which one of the following combinations is correct? 1. (A)only 2. (B)only 40 3. (A)and(C) 4. (B)and (D) 112, 31 dacier a Pe sider wer at var warns = Sflagerr wot ce Sree aafferor aT Here TT Bi araet gat weer & art Fr aor *s. ARE (CEe-sehla cael) a wer surreal deere aerate eaRT at apr ferofer fore @1 fasiorat a va am a SKia, Mena at vite sta Gece & wat ware gant scaa aR, Seema vensrer a fore zener ferea wer! fr Afere war aR wfafis a eer wfexan araatoor ae a Sait amy ger wider & safer eet Fr ater fereat af et fare sier at a? 1, are sfageer a 2, art sfrager aor a 3. steigedt snfear att sfager war atait & at 4. art urd yfearait ate siaeett ‘onferat a 112. You are following the intracellular sorting of an integral plasma membrane protein in a living cell, in culture. You have decided to probe this protein by metabolic labeling technique with “'S-methionine (pulse-chase technique). After one cycle of division, the cells were treated with a potent inhibitor of protein biosynthesis and processed for subcellular fractionation, In which of the following fractions will you expect the presence of — this ‘protein. upon immunoprecipitation with a specific antibody? 1.Only cytoplasm. 2.Only plasma membrane, 3.Both endoplasmic reticulum and plasma membrane, 4.Only secretory vesicles and endoplasmic reticulum. 113. arraeat gegrast & ar aiesht srt (pH 6.6) 8 facifaa vestatat (pH 6.0) & uftageat 3X MOP (Aaitet 6 aise) anfgat a ares at gertror A ae ‘after atet wait a dra pH & 3siaw oe fasit act &1 Mop anér aireeras site qadaor sik oigetatat A sarit wearer Fy oftarsit & dast A ary art & sree oe sacra fare ar aie fairer vestatat aH pH 6.6 & HT we aor far are at oRona ear star? 1, MOP @ggiesit ar aitétiet at wea ‘feet orgstetat a facifear wesrerat 4 saatfaa aét eto 2. M6P aiggtetsit Fr sider aT After srgidat at facifea weshetat 4 saat eer 3. Sea Westra pH W, mer aegis aT graareet agit atm sit saat areot art a yerdswor ai eT wera! 4, Sea pH WR Mop 3rgafea a Sea 113. The principal pathway for transport of lysosomal hydrolases from the trans Golgi network (pH 6.6) to the late endosomes (pH 6.0) and the recycling of M6P (mannose 6 phosphate) receptors back to the Golgi depends on the pH difference between those two compartments. From what you know about MOP receptor binding and recycling and the pathways for delivery of material to lysosomes, predict what would happen if the pH in late endosomes was raised to 6.62 . M6P will bind to hydrolases but will not release the hydrolases in the late endosomes. 44 2. MOP will bind to hydrolases and will release the hydrolases in the late endosomes. 3. At higher endosomal pH, the receptor would not release the hydrolase and could not be recycled back to the trans Golgi network. 4, M6P will be degraded at higher pH. 114. Pet omer at afeaferer setar FF 6.4 x 10° bp Stet & SH AE 6 pm SATE AeA a swgea wo a war oat eae amg ava St watt hse I 0.34 nm sientet ae PeaRta et at sha Aifore fe feet aca ater A st wav AT Hat cians free ast 1.3.0m 2.3.5 m 322m 4.4.0 m 114. The diploid genome of a species comprises 6.4 x 10” bp and fits into a nucleus that is 6 hm in diameter. If base pairs occur at intervals of 0.34 nm along the DNA helix, what is the total length of DNA in a resting cell? 1, 3.0m 2. 3.5m 3. 2.2m 4. 4.0m 115. Stet ar wearer aan Rett qeot A ongitat ar Afaceri wieder aafraarea cat F SUT wa dren & frat a wafer ard ¢ ud shar afteatta ft cite a Recap fersad anor axa 1 se TAT B seaeat area A aren oad qeat at wr Ue wey We far BET & aaa at yeni ater aa 1 Swat u ROTH anata sate 2 3. 4 St wr Ceca RE Par Ye aireer Beat oars Ver wr wfenifectenor gf wer west ween fer a agra & ‘arghter wr Afaeteor sie weer St wat weed weERe fara Br agrar & 115. Phosphorylation of serines as well as 116. 116. 117. methylation and acety! of lysines in histone tails affect the stability of chromatin structure above the nucleosome level and have important consequences for gene expression, ‘The resulting changes in charge are expected to affect the ability of the tals to interact with DNA because DNA is negatively charged. DNA-histone interaction is independent of net charge. phosphorylation of serine increases DNA~ histone interaction, methylation and acetylation of lysine increases DNA-histone interaction, B-DNA #1 Uh WS 5OkD anfvacy sme a fet worga at dei war 31 se as Fr um a eanfaer sang eet 1. 0.1547 2. 0.1547 x 10° 3, 0.4641 4, 0.4641 x 10° A segment of B-DNA encodes an enzyme of molecular mass 50 kD. ‘The estimated length of this segment in jum would be 1. 0.1547 2. 0.1547 x 10° 3. 0.4641 4, 0.4641 x 10 taht wet ot Waeet eit Gra area Ht afer site fasnorr ae wr €, s sacar A amt DNA A gia 42 wt ugdaiors wr waar ae al € ol ve WW weer seh at car F erge fort after war ye (30 ach, wena gar Barer engfasir faf@ra a ont fo) gee Sata area ar Reaareiga oreiaer & aren aaa fear ser wer were afatert war ae gfe aed aie fasnfore dct wet area oRadar & are Pepe war suid, iat a wa qereri garr sie ver) waryaOT HT xt wart srt weer oreat gana wor Yuga ony Foor fe aiferaisit ar ag ier forest Yeetafarer so owt uv fawn ¢ a Ta Yeataftar gant sie rar sr ara 1 aie gaat at aeie far & sq ergierstat eavcret & ware hr Pract & mar a areifer fre om waar B: sem th — BR SA Ups HT HT S am Fr ons ue sat Rant at aefar & sit fr Star seit BAT (S phase) S wat vfepianor WaT ae wy ae Usataies angiaser wt fers war al am & Rex aiarsit Ht M araeer aT eter & | 3. amp H 20 fac & smi wT Use wiftansit #1 wireltes sacar 8 Fae eI ae 4010 fae & snia sre saw aifrersit ar M sacar A faeaara eer etter @1 117. Cells that grow and divide in a medium containing radioactive thymidine covalently incorporate the thymidine into their DNA during S phase. Consider a simple experiment in which cells are labeled by a brief (30 minutes) exposure to radioactive thymidine. The medium is then replaced with one containing unlabeled thymidine, and the cells grow and divide for some additional time. At different time points after replacement of the medium, cells are examined under a microscope. Cells in mitosis are easy to recognize by their condensed chromosomes and the fraction of mitotic cells that have radioactive DNA can be estimated by autoradiography and plotted as a function of time after the thymidine labeling asin the figure below: ee The rise and fall of the curve is because: L.initial rise of the curve corresponds to cells that were just finishing DNA replication when radioactive thymidine was added (S phase). 2.the peak of the curve corresponds to cells in curve after 20 min corresponds to cells in apoptotic phase. 43 4.the fall in curve after 10 min indicates the cells exiting M phase. 118. & wa wfepiraror A sires Ar afte a sea at & far arqahnd: HBP th eet ar care Pear aren Brat areitator ae wT uot oft ar wart ay fear ae eT wa gt cheat waren aset airrsit at dar ot daftfar far ara, at 3eelet 100 aire feaeroret & aria at segtaae aetar sit arerdter wiftensit 4 reper at ora at BFA Sita Mae fe fara A a stare wer are 8? 1 war we wepiaarr a dat A deters tiga & atoctear ft ef a ara sik ase ape so A er aa e 1 2. 9, Aa ot ua wR a RY PR Soret & BROT Aaa st sre S aie a wt v fer wapioacr & fer Sretetar Fr srareeper wet ete | 3. ayet A ara Ft qa A wet var aa fea aren sires St wet w eT faquara eat 3 1 4 oF, aga St wa © sfetpiraeor at He wa U wisest & araeanat aét rat | 118. In order to study the role of telomeres in DNA replication, genetically engineered mice were prepared, where the gene for telomerase RNA was knocked out. When cells from these knock out mice were taken and cultured in vitro, they proliferated even after 100 cell divisions which is quite unlikely in the case of human cells. Which of the following is the correct reason? 1. Human and mice are fundamentally different with respect to their requirements for telomerase enzyme in the context of DNA. replication. 2.Jn vitro, mice DNA becomes circular due to end toend chromosome fusion and does not require telomerase for DNA end replication, 3.Mice have very long stretch of telomere DNA sequence compared to that of human, 4.Jn vitro, mice DNA. replication does not require the removal of RNA primers. 119. wrath 3 weferiecrnt WM yarecoet Wrag He Heat Meera g (A) We sfaier & far agdtargite Srrereeran Brat BI (B) Wie oRatier & few siifeerer arava erat 81 (©) stfeeet 8 agetargiv ar anya siecle sree eter 81 (D) dat, ag we we vRait & far Shofar seer arraere eta 21 Sitter Aifore far sortea wert ar feat A a spleen datorar HET 82 1 (A) ik © 2. (B) afk (D) 3. (A) ait (D) 4. (B) aK © 119. Following are few — statements for regeneration of plants from explants/tissues, (A) Cytokinin is required for shoot development, (B) Auxin is required for shoot development. (C) Auxin to cytokinin ratio is very important. (D) Jasmonic acid is required for both root and shoot development, Which of the following combinations of above statements is true? I. (A)and (C) 2. (B) and (D) 3. (A)and (D) 4, (B)and (C) 120, wa Worgarfagier fastoy x steer fafeee wire shar atten Breeton BORA andl og aS! aeft x vida & rer fare sft verre BY 7 (in vitro) Bt WaT U andter frarferar fr aearet gt Ar or Bt, ae se (in vivo) ARATE athe Um RRA spree aren a aT we frehater 1g 7$ | smird Ghai a gar a feast A a ata UT weet UaheceT Cane WET AAT 8? 1X Ua Sf wat U snetrer vier & 1 2X separ ara eer wgfaa freer a ompR WER Bear ae a 3.X miata ar saree arr a fore waictte ae & 1 4. X Ua efter F 1 120, A non-enzymatic viral protein X was found to be inducing a cellular gene promoter activity. Although no in vitro DNA binding activity could be identified with X protein, it was found to be co-recruited on the cellular promoter along with a cellular transcription factor in vivo. Which one of the following statements seems to be the best interpretation of the above findings? 121, i. 1.X is a DNA-binding protein. 2.X physically interacts with the transcription. factor. 3.X modifies the chromatin for transcription activation. 4, X isa chaperone ST ot wa Oe BabA sree Hz & oe at a we Bet dat area sik sreeefader war Gel WA BIN Wet T (mRNAs) HT SeTTET Peal st A sa ae WA I wa Tit (mRNAs) @Y Faetarsrr wife dear facet & arr sofia fear sie fe Herr-stent Seoreh aT at euie far a HeET aoa PRT! Shere AtfSre fas AT fer ae amt a a ata a ata oftomat ar agt eo a aetar 87 me 2 5 stata Nate i | i | H il ‘oot Ut ido Ge Set ened —— ae You are working with an in vitro eukaryotic transcription system, which produced both capped and uncapped mRNAs. You incubated these mRNAs with mammalian cell nuclear extract and then quantified the different products as shown below. Which of the following graphs correctly represents the expected result? 45 a As i i i ‘Capen Uncaromt ow enea 122, (a) (B) © it fl Lid os i Lem’ |_| sr fer ge onfaqedtr ger aA, emer cragat fet fafse dena & ware BT oRadat der F sama & art 1g F | ge gar a fr farat orca fae are a: Sfraroy sift (Archaea) FY apart ‘gear (Eukarya) & freee aeaieut él Stary ait safer ww get a, ent a fret ca & ghar & quar a, we Hite wars i anita ai afar wagRt &, sah aderea yar & stay H ator et a OG, avatar at ae a ata Afar PR Rat a a sear daar wet feat aetar & 1. (A), @) 3k © 2. (A) HR (B) AT 3. (@B) ait (© Ar 4, (A) ai () arr 122. Baye ete, Archaoa In the phylogenetic tree above, branch- lengths are drawn proportional to the number of changes along a lineage. ‘The following inferences were made from this tree. (A) Bacteria are more closely related to Bukarya than to Archaea. Bacteria and Archaea are more similar to each other than either is to Eukarya. Archaea and Eukarya diverged from each other after their common ancestor diverged from bacteria, @) C Which of the following represents a combination of correct inferences? 1, (A), (B) and (C) 2. (A) and (B) only 3. (B) and (C) only 4, (A) and (C) only 123, at A feat ARG eer aT weet Serer Be H ware A ae sen aa Pe gt at eft Psy qanr ants aét fear ot wear! Bie Area Fa WH fas tina & ofa yer et F fre were & oie ara ar SoteteT aan afte a ter wait ae vest et we at oat wey ae aopire Bt Be: aa fee ge fanest AS wet ater ar rat AifSTT: 1. eR er asa sit abe PasToy A TTT wheter Fr aifsteuterer axe #1 2. Uap tar ayer Sit oe aera aTgt Shter Fr aitoaita acer st areet ste afer Faso] & smazieor & fore wiftenr Teel sitéter apr ferator arxeit 81 3. ue tar aye st mad MHC at 1 faeax stare sr aiteattar are 81 4. wa tar aye ot ser arera angt sitet Fr after axa at sa ver a wiftrer aaer steer ar fevator arcit &, fat areata ofaer fasIey arden weer Get ster sft et at daar ow ge foo Ar aagt weer fr sroaftr anret Fr aetat anor aeett @ | 123, While attempting to create a disease model of poliomyelitis in mice, it was found that mice can not be infected with the said virus. Since human beings are susceptible to this viral infection, which kind of transgenic mice should be generated to have a transgenic ‘mouse model that can be infected with polio virus? Select the right approach from below: 1. A mouse expressing surface protein of polio virus. 2, A mouse expressing human receptor gene which makes cell surface protein for docking and internalization of polio virus. 3. A mouse expressing human MHC class I invariant chain. 4, A mouse expressing human receptor gene which makes cell surface protein for docking and internalization of polio virus along with a gene designed to express surface protein of this virus at puberty. 124. sa Afar fear A a shee aw ORE CaN Weilet seat Bw a we oe A outer 2 124. Which of the following curves correctly represents the process of ethanol production by yeast? t 12sate Seat aH sim a Tet A waa woh aa Scot et aT | aft ae wag gfe ara Safer age dea a) sta Ae fh art & ng faftat A a staat war oo 8 fast oeieh seq eT 47 2. 125. wait eonpast daft & waa semet & fae os deat A qeier Net at voreret ( PaROT ) Ger WaT asat 8 are aeel Sat cher a soea steve F aaa afer Rit rt dafe & wad setae & fore waa caste ATT a Wan aa wee of aet a ae aT Inbreeding for 5 generations led to production of homozygous transgenic mice, However, these homozygous males or females were infertile. Which of the following approach is most preferable and economical to obtain heterozygous transgenic animals continuously? 1, More transgenic founder (1* animal) should be generated. 2. Crossing (breeding) of transgenic mice with wild type mice in earlier generations should be done for continued production of transgenic heterozygous offspring. 3.Inbreeding should be avoided after 5 generation. 4, Homozygous transgenic mice should be mated with wild type mice for continued production of transgenic heterozygous offspring. 126. vara Ae a UR BCT Bt UT wag & fasnfsrar fear avert) waR 1 & aanqgat at Pet ofeoret & ae at ster arm BR 2 FY KLH aT aa & fae welts ata atk Macat aa fear aan wa 3-H AaNEaT 2 1. after Rohe ars ( ver Sey) aT semed gear aeT | wr meat KLH & arr ifs fear ae, Of grat engaedeecr fear aa! wag 4% wamaget at KLE fer aren, engatedtper farar aren, Afar KLH- faftee cpa" T attest & arer yer: defer fer vem gear weft aeat at sigan wrest ater og, KLH & arr fateh feafa a cer mar sik ufe- KLHIgG vfefis ar araet dat a Pre aa ga Ase R fer A a ata wiaftis veqeat ft Arar ar uel stepReT e [>= greater than, 2 = greater than or equal to} 1, Group 1 > Group 2> Group 3 > Group 4 2. Group 2> Group 1 > Group 3 > Group 4 3. Group 2 > Group 3 > Group 1 > Group 4 4, Group 4 > Group 1 > Group 22 Group 3 126, A set of neonatal mice are divided into four groups, Group 1 neonates were not primed ‘with any antigen, Group 2 neonates were primed with KLH, Group 3 neonates were primed with KLH but thymectomized. Group 4 neonates were KLH-primed, thymectomized, but reconstituted with KLH- specific CD4" T cells. All these mice, when grown adult, were challenged with KLH and the anti-KLH IgG antibody was measured in sera, Which of the following is the correct order of magnitude of antibody response? [> = greater than, > = greater than or equal to] 1, Group 1 > Group 2> Group 3 > Group 4 2. Group 2> Group 1 > Group 3 > Group 4 3. Group 2>Group 3> Group 1 > Group 4 4, Group 4 > Group 1 > Group 2 > Group 3 127,fret sede a et aret Morseht & fore wr av ag A Gtr AS a ae siete sige srefer Beards Br TeRTET axa Ugeat em se sie se ofa wfaftis at saerer at gt war, after wie Greats wet et sem sft ioe fe Ber A a strat afer 48 waite esta: weer A ueETET ath? 1, Grp. ant aaraat steer hr was awARraT tar A aeafta A oral & atk gear LC-MS/MS. @aRt faeetsor fer star 2. GEP-mnét derret sider Br war awifReRT ar aH afteateer Ar snc & ate GFP & fae warren afar a ster ax afta ae ait wa oifermrarcrengs Stet OE TEA FAT 3. GEP-amgt sidiet at WR TengET (ELISA) wat oe arelfter ae flee gear wfet-GFP sfafts & ener warger Pre ara | 4, mgt ar GRP Fy wa eoraet sitet a eo A aeleat fear mar site adit aftenit A after = rar are wia-crp wfafis & ganr sfarat- gaat sft et LC-MS/MS @a@Rr faedwor fare seri 127. An investigator discovers a new receptor for ‘a known ligand and wanted to identify the binding partner of the receptor i. its co- receptor. ‘The antireceptor antibody is not available but anti GFP-antibody is available. Which one of the following strategies is most likely to identify the co-receptor? 1. The GFP-receptor fusion protein is expressed in a cell line and analyzed by LC-MS/MS. 2. The GFP-receptor fusion protein is expressed in acell line and the cells positive for GFP were sorted out, lysed and run on a polyacrylamide gel. 3.The GFP-receptor protein is coated on ELISA plate, followed by ELISA with anti- GFP antibody. 4. The receptor is cloned as a fusion protein of GFP and expressed in stimulated cells. The immuno-precipitated complex obtained by anti-GFP antibody was analyzed by LC- MS/MS. 128. Ad at Wat at A at aie at erfer & qa Sagat ar aRFanar fear after fear sar &: ovr te F r i i "a woe sia Afar fH ag sie & fae a Rea aT get Ht Sagat ae as vara ogat @, aro fara A a steer ‘aifeaa feds cafes wet 2 1. othedt fr qorar & fer + teror 2. ate aah fr wa orn aoe 3. eet sik sth gar Surat ar Terrace facet 4, ger Sears ar aca we wieRACT 128. The frequency distribution of tree heights in two forest areas with different annual rainfall are given trem neneee roa wan et Which of the following statistical analysis will you choose to test whether rainfall has an effect on tree heights? 1. test for comparison of means. 2.A non-parametric comparison of the two ‘groups. 3. Correlation analysis of rainfall and mean tree heights. 4. Regression of tree heights on rainfall. ‘8/46 BJN3-3BH—4. 49 129, facta Hr feafeat a sree ae oielt-L- arent Ye o-gecht, paar sie arefeay gefea deat a Paquin oer orat & | ge otiaters & aged, pore ate arefite deft deat a sitaa sae aeigedan API A: 220 ram ({@Jz20) F -35,700, -13,800 ate +3,900 deg cm*dmol" 1 ag viferIerss_ pH 10.8 HR 25°C WE apse sear aH eT Wet & | after at Part F at sraensit cgact ste areas gach gear & ate ofa star 81 ag ora arr & PR 6M after # sofeafa a cifras FT [O22 -14800 deg cm*dmot" gta 81 Se Uifertcergs F a-gschh sear aa veer & 1.37 2.41 3.47 4. 50 129. Poly-L-lysine exists in pure a-helix, B-sheet and random coiled conformations depending upon the solvent conditions. The values of mean residue ellipticity at 220 nm ({@Jza0) are -35,700, -13,800 and +3,900 deg cm’dmol" for achelix, B-sheet and random coil conformations of this _ polypeptide, respectively. The polypeptide exists in o— helix conformation at pH 10.8 and 25°C. Addition of urea leads to a two state transition between a-helix and random coil conformation. It has been observed that [8]: of the polypeptide is -14800 deg cm’dmol" in the presence of 6M urea. The percentage of the polypeptide in a-helix conformation is: 1.37 2. 41 3.47 4. 50 130. velar igen a Aelfancor aor a He, eartieor mRNA Bie AfEEATeT -RNA BT ugdia a ear Y we welt arate wet 1 hens H GTP ste ER-G Paria Bag aa E 1 aeet Bear aragg, wet erate GTP HT ER-G & tacts of eigesr gt wear B1 Bt aroit a sree ae feet URaersTe sreget Bt om arch @: (A) araiener Fr ort sufbaer afaiisrer aha aifBiisrear & yvter Beer | (B) Sarerrareer fereafleraA GTP stet sree 8 tadt SI (© eaatiarer Brareiterat ora: GTP ait EP-G & arte & 1 (b) Seraiaeer Brerefterat Ugateait FH siafaiftr at & ATT euraieror ex GTP sik EF-G ht sufeafe a vata wr a ag sit 1 aia AC fe fer a a saa aatoret Ber 2? 1, Ha (D) | 2. (A) SIR (C1 3. (A) 3K (B) I 4, (C) 3k (D) | 130. During elongation step of protein synthesis, translocation moves the mRNA and the peptidyl tRNA by one codon through the ribosome, Translocation in E. coli involves GTP and EF-G. However, in vitro translocation can take place independent of GTP and EF-G. Based on these observations, the following hypotheses can be made: (A) The molecular mechanism of translocation in vitro is completely different from that’ in vivo. 50 (B) Translocation activity is independent of GTP hydrolysis. (C) Translocation activity is _ completely dependent on GTP and EF-G. ‘Translocation activity is inherent in ribosomes, however, the rate of translocation in vivo is enhanced ignificantly in presence of GTP and EF-G (D) Which one of the following combinations is correct? 1. only (D) 2. (A) and (C) 3. (A) and (B) 4, (C) and (D) . 131. det atch & arrare sare var WaT Bl gat @ yer ada wy We oH A, 325/km? a ueica oe Pewaret 8, FRx arr ww at outer B, 119/km? 3 Ueiet we FaquaeT 8, chee adr oy, ale a ait B onftah sare 297/km? = 3H 150/km? weet OT Raqgeret 1 get Pa A A stra hort Frac ST aA 8? 1 dat onfeat wr get a vfeeset aig ar wer E | 2. gat siete wfaatrar, sierronft weiter $Y gaat Ht afte cia & 1 3. gare aiawenia = widatfrar, sient wieeiiirar gear # afte alae 1 4, sit atte atraronfer wfeenftrare weer ctaat Fr € | 131. Three islands have identical _ habitat characteristics, On first island rodent species A js present at a density 325/km’. Second island has only species B at a density of 132. 179/km?. On the third island, both A and B co-exist with densities 297/km? and 150/km’, respectively. Which of the following can be inferred from this? 1.The two species do not compete with each other. 2. The intra-species competition is more intense than inter-species competition. 3. The inter-species competition is more intense than intra-species competition, 4. The inter and intra species competition are of the same intensity. aietrat a gd wr wt Afece aiaeas Paria & siete ww Agcy ager ar fader aear &1 Sar oer aa & f& Pet ofa & facadf ata sik gmt agar a ak fF wT Ader ae e aay we fauta weday git & a gee wattcter ait ag gr seta & mex der weed 31 arta Ap aera giver pear seater A wR ore areata aft Sl aA 88 ah Srivatifaer piwar & ear saver das ee wa at saat wpateer omer eta) dear arr & far ae B deatar atrat ar s-torengiegter wearer at & ome at aa ven ata A Ravahfaar aT RR a oa F HT wt arenfeaa ee BI Sira Afar PH storages & dest 4 Bea 4 O ata wee ae at 1. ter aAtend st stomegteda vara A an ont & sa argiedr eat & ft wa UA aanface we Sat a 51 132, 133. stararsfesit af va 0 ART aT wr AT tat & damaged feed ufafectaor at SOR eta & staragtgia stat afreaftr at aR wet aKa & DNA methylation plays an important role in transcription regulation in vertebrates. There is an inverse correlation between the level of DNA methylation in the vicinity of a gene and its transcription rate, whereas there is a direct correlation between histone acetylation and increased transcription, B-thalassemia is a common genetic impairment of hemoglobin B-chain synthesis in humans. If these patients can synthesize hemoglobin-F instead of hemoglobin B-chain in its place, they would be notably benefited. Administration of S-azacytidine to B-thalassemia patients increases hemoglobin-F level in erythrocytes and thus benefit the patients. Which one of the following statements about S-azacytidine is NOT correct? Cells exposed to S-azacytidine incorporate it into DNA in place of cytidine. azacytidine decreases DNA methylation. azacytidine promotes histone acetylation. S-azacytidine does not promote gene expression. Pret at A cach Ft et anfaet Ar 32 waedt a ote ah of 1 AT syeeuar & fae ster sty ROT wre 162 se 48 cen sift 2 & far 3.6 aie 3.2 8 gat roast & cant ga Faget A dat onfat & aor & val A fart AS et eet ar wala gta 2? aat onftai uefa wa & facta & 2 sf 1 at weft wr ad feat & wafer sift 2 as at 3. oft 1 gis AS safe orf 2 at arefeiar wr @ face & 4, dat snfaar as a fate & 133. Two species of plants were sampled in 32 quadrats in a forest, ‘The mean and variance for the occurrence of species 1 were 16.2 and 48 and species 2 were 3.6 and 3.2 respectively. Which of the following statements about the distribution of the two species in these quadrats is supported by these findings? 1.Both species are distributed randomly. 2. Species 1 is distributed randomly and species 2iis clustered, 3,Species 1 is clustered and species 2 is distributed randomly. 4, Both species are clustered, 134, tat alan feet G wer after mgt faquaret om, sismeTay ameter A weet aigetet A aaRT dart HET WT desist 3idtret itéret (ABP) 3H CREB wheat ar sieht we TAT | cAMP, Sit A og 8, % art a 1. ABP aT sefctaet Ie TTTT | 2. CREB Wet a wench a sav | 3, eperaet GAT Ie a ORRaciet art sta 4. Go save FY GTPase frame ae arest | 134, In cells having G protein coupled receptor, inhibition of protein kinase A by siRNA technology led to diminished transcription of androgen binding protein (ABP) and CREB protein. Addition of cAMP, which is a second messenger, will lead to 1 increased transcription of ABP. 52 2. increased phosphorylation of CREB protein. 3.no change in transcription level. 4. increased G'T'Pase activity of Ga subunit. 135.ter were & fe ser ahr wife arta Ber itehfeeiter aifttenait & Reefer gS & aati ero ft afeorar aor. Seth B. 1 ae ax 2, Salt seer er aera 3. gapior a oA weareera 4, srerreper fererrer Sree TROT aT Fr aTeTaT 135, Complex eukaryotic cells may have evolved from simpler prokaryotic cells because complexity of organization increases the 1. growth rate, 2. _ efficiency of energy utilization. 3. tolerance to starvation, 4, ability to attain larger size, 136. aie fret fetes ar aerate mer 2. SO ander ae fear ome at 4 sicier aagaat & srepaftes after a ater Swe streamer eet oreReTOT oar ‘afer a one & | serch after Yer Aa, ae mete we dha after a we Haga wider cant arated wa & oa fe agit atfter tare a, ae maga BRT BT A Rawt ates ad el ame sige fet A alae ‘rsa wer at & 2 wifter A A dat oT afl ser ett | aie A A sea Beat OT aarit & fede dur at aera artearga war ete | 3. wien A a eat vader A wesraaT arta aiftter ett 4 wet Ba sea doa oat a area Bw wae Ft ata stearper Sear eter | 136. Binding of a ligand to a cell-surface receptor activates an intracellular signal transduction pathway through the sequential activation of four protein kinases. In the human cell A, these kinases are held in a signaling complex by a scaffolding protein whereas in another cell line B, these kinases are freely diffusible. Which one of the following possibilities do you think is NOT correct? 1. Speed of signal transduction will be higher in cell A 2. Possibility of cross-linking with other signal transduction pathways will be lesser in cell AL 3.Possibility of signal amplification will be higher in cell A. 4.Potency of spreading signal through other signaling pathways will be higher in cell B. 137.06 C8 var A ot wad 50 af aa (A) (B) waa wr %, Heat ae ta est & dart & wane 71g %, Pray atsit 4 de ff seca arr et ae oar aa & fe aden 4 sia do arr ae serie a feet a cect A aria afte g1 se Sarr Fy carensit & fae far uRtaerant seater Fr ag ef: we oseaRade | wedet ‘for woraed dat A da A ArT as 7S) sea dent ent wer wh dafear set wet & for aBMRa far a faerh dist A der fr wel wet gS aT i 146 BJ/13-3BH—S. 53, © 137. 138, ) ART A HITT ert & telat Fr agt BS anrarar seraka BS, free sik sft sear deer att stat & dalstet ar freer gar | Sita fae fe fer A a stra wer went ar datort cuter 8? 1. (A) site (B) arr 2. (A) #R © aR 3. (8) HR © aT 4. (A), (B) 3k © In an experiment that has continued for more than 50 years, corn has been: propagated by breeding only from plants with the highest amount of oil in the seeds. The average oil content is now much greater than any of the plants in the original population. The following hypotheses were proposed as explanations for this observation. (A) Mutations occurred that increased the oil content in seeds. Plants with high oil content were stimulated to produce offspring with more oil in their seeds, The breeding led to increased frequency of alleles at multiple loci, so that new combinations of genes for even higher oil content were formed. (B) © Which of the following represents a combination of correct statements? (A) and (B) only (A) and (C) only (B) and (C) only (A), (B) and (C) we atl tr & oat ger et adh dea 4 wernt sraffa axa oar aren | Ofer gar ect A feet eft sae e wee a sewer ae a wT AT Repo Sita Ase fe ge veror Ar ee a fara Ha ated aden corer et ‘aac formcadtt ata # ater goa ait ania & agg AG 3eT oTe Safe a aa BL 2. fermeacth ata a after quae atg arr Sofa at & sta: oeerorantt ger one Fr atte amet & fore are ¢1 3. REMY aesae: sre-at ager & ‘after #1 4. URTeToreRY ara afiey aol ay Ser wee BI 138. A plant with blue-coloured flowers was observed to attract a large number of pollinators. However, these flowers were not producing any nectar, Which of the following can be a logical. explanation to the observation? 1. There could be another species in the vicinity that has blue flowers and is rich in nectar, 2. There is no other species with blue flowers in the vicinity so pollinators are compelled to visit this species. 3.Pollinators may not have blue-colour vision. 4,Pollinators may be able to see only blue colour. 139, ararenvie oReaiaat seppeite ayerat a ofeat & daar at weariea ar aad @ 1 at few ae faa A at Ar oifeat a wae & urea aa at URaciet a aa waftter fe are gyfer fae fe ant & fee fer a a ata ‘at ott wet 54 A= Tega, BARA, Coreraett Asner, Boarefadl, C-rnRar Asntaadl, B=aaitady, C-refRaT Aswad, B-rtaadl, C-refREt 139. Environmental conditions can influence accumulation of species in successional communities, Curves representing changes Bere in forest species over time are given in the figure below, Which of the following keys is correct for the curves? intermediate, B = xeric, .A = intermediate, B= mesic, C= xeric 4,A = mesic, B= intermediate, C = xeric 140.ue snfe Fe yfeer wd Sheer Gharsrg) wa ae ain A qreenite Pee ae) sah sere HS Higat aa aaaftr & a7g car set art & fr 3 atgee test cefer: eee softy a attra aaror test fy career at ater 8? 1. Fenway falar afeqaretigfeat arte sheer et aft) 2, fererer aT STAT 3. 4. 140. 141, fedfad dite ofaraar Sieareeet oRatir a sett arta ear A few males and females of a species were introduced to a new island. Their population Was monitored over several generations and followed a pattern shown in the figure: Which of the characteristics of the species does NOT explain the pattern? Skewed sex ratio (more females than males) Large litter size Delayed sexual maturity Effects of intra-uterine development on fecundity vray seafer | (wageicieie) ar wage & fee asa warda (MEL) witarit at cw ot aren cater wise & wo A sot fear oat F | gat atari at saiawr aT WeRAERS Hae AH sel ae fear stat 81 gat AHI at Gr can ant falar & few afte fre or arat § anf ag salschiser ar Aer at hl ga wa A waite ware aifvars after ag et wart & fe eer 3a Hasta Sr frat aravtere (HRI) aig BY Behera sateen seer e aX Tha 8, St selfs Pear a TH ales & sa Heifer B weEIET fatter srrafta ef atat & | Be oReeva a Fed ae & fae fara 4 & stash it sha Le 2 1.HRI aigetot sft et MEL aifrersit at eaaiahta aa 2.MEL @arsit A faqmart HRI aigetst oft BY BACT aL car 3. siéter Seerwor Ft ax ar favlaet & UH Ber & wT A caret freer aA 4. HRI aigetat fsa ar fastest a wa Bea & wT A A AT 141. Mouse erythroleukemia (MEL) cells are used as an in vitro cell culture model for understanding erythropoiesis. These cells are arrested at the stage of pro-erythroblast due to transformation. These cells could be induced by heme to differentiate further so as to synthesize hemoglobin, The most probable molecular mechanism for this could be that heme may suppress and/or downregulate an endogenous heme-regulated inhibitor (HRI) kinase, an inhibitor of globin synthesis. ‘This downregulation in tum —_ promotes differentiation. To validate this hypothesis which of the following approaches is NOT appropriate? 1.Transfect MEL cells with HRI kinase gene. 2. Knock down HRI Kinase gene in MEL cells. 3. Determine the rate of protein synthesis in situ as a function of differentiation. 4, Measure HRI kinase activity as a function of differentiation. 12.

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