DAFTAR ISI

BAB I Pendahuluan
1.1 Latar Belakang............................................................................................

BAB II Thalassemia
2.1 Definisi Thalassemia.................................................................................
2.2 Epidemiologi.............................................................................................
2.2.1 Mortalitas dan Morbiditas................................................................
2.2.2 Usia...................................................................................................
2.3 Patofisiologi...............................................................................................
2.3.1 Produksi Rantai Globin....................................................................
2.3.2 Patofisiologi Seluler.........................................................................
2.3.3 Hipotesa Malaria...............................................................................
2.4 Klasifikasi Thalassemia dan Presentasi Klinisnya....................................
2.4.1 Thalassemia-...................................................................................
a. Silent Carrier Thalassemia- ......................................................
b. Trait Thalassemia-......................................................................
c. Penyakit Hb H..............................................................................
d. Thalassemia- mayor...................................................................
e. Thalassemia-..............................................................................
2.5 Stadium Thalassemia.................................................................................
2.5.1 Stadium I...........................................................................................
2.5.2 Stadium II.........................................................................................
2.5.3 Stadium III........................................................................................
2.6 Pemeriksaan Penunjang..............................................................................
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2.6.1 Darah Tepi.........................................................................................
2.6.2 Sumsum Tulang................................................................................
2.6.3 Pemeriksaan Khusus.........................................................................
2.6.4 Pemeriksaan Pedigree.......................................................................
2.6.5 Pemeriksaan Lain.............................................................................
2.7 Terapi.........................................................................................................
2.7.1 Transfusi Darah................................................................................
2.7.2 Komplikasi Transfusi Darah............................................................
2.7.3 Terapi Khelasi (Pengikat Besi).........................................................
2.7.4 Transplantasi Sel Stem Hematopoetik (TSSH)................................
2.7.5 Terapi Bedah....................................................................................
2.7.6 Diet...................................................................................................
2.8 Skrining.......................................................................................................
2.9 Prognosis.....................................................................................................

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BAB III
Simpulan..........................................................................................................

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DAFTAR PUSTAKA......................................................................................

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