REPUBLIC OF THE PHILIPPINES DEPARTMENT OF HEALTH “ MI rooD AND DRUG ADMINISTRATION Food ond Drug Aimistratin Civic Drive, Filinvest Corporate PHILIPPINES. Alabang, City of Muntinlupa PHILIPPINES 03 April 2012 FDA MEMORANDUM CIRCULAR No. 2012-003 TO : All Drug Manufacturers Applying for Renewal of License to Operate (LTO) SUBJECT : Full Compliance to Good Manufacturing Praetice (GMP) In Tine with the implementation of RA 9711 or the “Food and Drug Administration (FDA) Act of 2009”, which aims to protect and promote the right to health of the Filipino people and to establish and maintain an effective health product regulatory system, it is hereby reiterated that all Drug Manufacturers applying for renewal of License to Operate (LTO) should ensure full compliance to Good Manufacturing Practice (GMP). For your strict and immediate compliance. SUZETTE H. , MD, FPSECP Actin Director 1V