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Jana Novotn
Dept. of Biochemistry
AMINO ACIDS
L-isomer
L-isomer is normally found in proteins.
Week acid
Week base
Proton
donor
Proton
acceptor
Izoelectric point
Dipolar ion
Fully protonated
form at wery low pH
Proton
donor
Proton
acceptor
HA
H++ A-
[H+] [A-]
Ka =
[HA]
[H ] = Ka x
+
[HA]
[A-]
[HA]
-log [H ] = -log Ka -log
[A-]
+
[A-]
pH = pKa + log [HA]
Nonpolar
Neutral polar
Charged polar
Methionine (Met)
Alanine (Ala)
Phenylalanine (Phe)
Valine (Val)
Proline (Pro)
Leucine (Leu)
Tryptophan (Trp)
Isoleucine (Ile)
http://www.indstate.edu/thcme/mwking/amino-acids.html
Alanine
Leucine
Valine
Isoleucine
Methionine
Phenylalanine
Threonine (Thr)
Tyrosine (Tyr)
Cysteine (cys)
Asparagine (Asn)
Glutamine (Gln)
http://www.indstate.edu/thcme/mwking/amino-acids.html
NH2
S
Asparagine
Glutamine
Arginine (Arg)
Histidine (His)
Lysine
Methionine
Threonine
Phenylalanine
Tryptophan
Glycine
Proline
Serine
Cysteine (from Met*)
Tyrosine (from Phe*)
http://www.imb-jena.de/~rake/Bioinformatics_WEB/gifs/amino_acids_chiral.gif
Intermediates of biosynthesis of
arginin and in urea cycle
Ninhydrin Reaction
This strong oxidizing agent
bring about the oxidative
decarboxylation of amino
acid. The ammonia and
hydrindantin forme
ninhydrin, a purple
pigment.
NH3+ C
amino acid 1
amino acid 2