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Anatomy and Physiology
Definitions
Gross anatomy: structures can be seen with
unaided eye
Microscopic anatomy: tissues are studied
using a microscope (magnification of 401000 times), also called histology
Comparative anatomy: comparisons
between species
Definitions (continued)
Embryology: study of development in
utero or within the egg (e.g. birds)
Morphology: pertaining to structure
Physiology: pertaining to body-organ
function, individually and collectively in
systems
Cutaneous Anatomy
Skin consists of two layers: epidermis
(outer layer of epithelial cells) and dermis
(corium, composed of connective tissue and
vessels)
Glands of the skin include sebaceous (oily)
and sweat (sudoriferous) glands
The dermis also contains sensory nerves
and arrector pili muscles
Types of Joints
Ball-and-socket (shoulder)
Hinge (elbow)
Pivot (neck)
Gliding (vertebrae)
Ligaments span joints outside the joint
capsule, within the capsule is synovial fluid
Extensor (straighten)
Flexor (bend)
Abductor (move away from midline)
Adductor (move towards midline)
Muscle Metabolism
Aerobic
ATP breaks down to ADP releasing energy
Muscle glycogen breaks down to generate more
ATP, produces lactic acid which is oxidized to
carbon dioxide and water producing energy
which liver can use to resynthesize glycogen
Heart
Veins, arteries, capillaries
Lymph vessels and lymph nodes
Spleen
Red marrow (bone marrow)
Heart
Typical human heart pumps 60,000 miles of
blood through blood vessels each day
By 70 years of age a human heart will have
beaten over 2.5 trillion times and pumped
more than 435,000 tons of blood
Veins
Thin walled with valves
Carry blood towards heart
Capillaries
Tiny, one-cell thick
Systemic Circulation
Heartbeats are coordinated by the sinoatrial
node (pacemaker of the heart)
Systemic circulation refers to the heart and
vessels that move oxygenated arterial blood
from the left atrium and ventricle
throughout the body and then returns it via
veins into the right atrium (from which it
goes into the right ventricle and then the
pulmonary circulation)
Portal Circulation
This is a subset of the systemic circulation
located in the abdominal cavity
Takes venous blood from the stomach,
pancreas, small intestines and spleen
through the liver for filtering and processing
of nutrients prior to return to the heart
Pulmonary Circulation
The pulmonary artery receives
unoxygenated blood from the right ventricle
and carries it into the pulmonary circulation
Within pulmonary capillaries associated
with alveoli of the lungs, oxygen diffuses
into the blood while carbon dioxide is
released into the airways
Pulmonary veins then return the now
oxygenated blood to the left atrium
Lymphatic System
Lymph vessels collect tissue fluids, are
filtered through lymph nodes and then
returned to veins of the circulatory system
Lymph nodes filter out foreign cells and
materials and produce lymphocytes
Lymphocytes produce antibodies and also
destroy foreign and infectious cells
Blood Composition
50-65% of blood volume is plasma
Contains 90% water
10% solids include salts, proteins, enzymes,
antibodies, hormones, vitamins, minerals,
glucose, clotting factors, etc. (clotting of plasma
leaves a fluid called serum)
Hemoglobins
Hemoglobin within erythrocytes gives them
their red color
Consists of heme (an iron-containing
porphyrin) and a globin (a protein)
Readily absorbs oxygen forming
oxyhemoglobin
Abnormalities in Hemoglobin
Anemia = inadequate amount of
hemoglobin (or decreased #s of
erythrocytes)
Sickle-cell hemoglobin (result of a gene
mutation, common in some races of people)
Blood Types
Antigens are substances capable of
producing an immunological response,
usually in the form of specific antibodies
directed against the antigen
Red blood cells can have a variety of cell
surface antigens coded for by different
genes
Different antigens = Different blood types
Blood Types
Antibodies against cell surface antigens will
agglutinate cells (clumping)
Humans: A, B, O series (genes A, B, a)
Gene A produces antigen A
Gene B produces antigen B
Gene a does not produce antigens
Human Transfusions
Type A can receive type A or type O blood
Type B can receive type B or type O blood
Type AB can receive any blood (universal
recipient)
Type O can only receive type O blood (but
can donate to anyone, universal donor)
Human Rh Factor
Another type of antigen on human
erythrocytes is the Rh factor
If have Rh factor are called Rh positive
If lack Rh factor are called Rh negative (and
will produce antibodies against Rh positive
cells if received from a transfusion or
during birth of an Rh positive baby to an Rh
negative mother---do not occur naturally)
Erythroblastosis Fetalis
When an Rh positive baby is born to a mother
previously sensitized and producing antibodies to
Rh, these antibodies can cross the placenta and
agglutinate the erythrocytes of the baby resulting
in severe anemia or death
Sensitization can often be prevented by treating an
Rh negative mother with an anti-Rh gamma
globulin immediately after the birth of each Rh
positive baby
Blood Typing
Blood typing tests for cell surface antigens
Useful in parentage testing
Certain blood types are associated with
superior performance (e.g. egg hatchability
and egg production in chickens), others with
genetic disease (e.g. PSS and PSE in swine)
Useful in avoiding problems of blood
incompatibility (for transfusions and
breeding of domestic animals)
Accessory organs
Liver, pancreas, salivary glands
Nostrils (paired)
Nasal Cavity
Pharynx
Epiglottis
Larynx
Primary bronchi
Bronchioles
Respiratory
bronchioles
Alveoli
Birds also have a
voice box syrinx and
air sacs
Respiratory center (in
medulla of brain)
Peripheral Nerves
Bundles of neurons bound together form a
nerve trunk, these may be covered with
myelin forming a medullary sheath
A bundle of nerve cell bodies found
together outside the CNS is called a
ganglion
Neurons receiving stimuli are termed
sensory or afferent neurons
Neurons conducting impulses are called
motor or efferent neurons
Cerebrum
Cerebellum
Pons
Medulla oblongata
Spinal Cord
Located within the vertebral column
Main line between the brain and each part
of the body
Sensory (afferent) impulses come in
through dorsal roots of the spinal nerves
Motor (efferent) impulses are transmitted
through the ventral roots of the spinal
nerves
Kidney architecture
Cortex
Medulla
See Figure 10.20