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Worm Infestations

Entamoeba Histolytica
Taenia Solium
Taenia Saginata
Dr.Tahseen Kazmi

Life cycle of E.histolytica

Etiology & mode of transmission

Which form is infective for humans?


Trophozite or Cystic

Mode of Transmission:
Person to person
Faeco-oral
Sexual

Trophozites emerge from cysts in


Stomach
Duodenum
Colon

Etiology & mode of transmission

Carrier State
Non Invasive form

Invasive form
Ulcers
Perforation
Amoeboma
Liver Abscess
Lungs
Brain

Clinical Features
Asymptomatic
Abdominal pain
Diarrhea alternating with Constipation
Stools with offensive odour
Bloody diarrhea
Liver enlargement & tenderness
Cough
Right Shoulder Pain

Diagnosis
Stool Examination For?
Immunodiagnosis by Indirect Haemagglutination
Molecular Diagnosis __ PCR

Prevention and Control


Boiling of water

Use of absolute 1 micron water filters


Avoid eating raw vegetables
Eat only those fruits which you can peel
Avoid eating at road side vendors
Proper disposal of human excreta
Screening of food handlers for career state

Management

Metronidazole 800 mg Tid for 5 days

Tinidazole 2 gm OD for 3 days

Chloroquine 300 mg for 2 days then 150 mg for 14 days


BD

Furamide 500 mg Tid for 10 days after initial treatment


to eliminate luminal cysts

Taenia Solium &Taenia Saginata


Causal Agents:
The cestodes (tapeworms) Taenia saginata (beef
tapeworm)
T. solium (pork tapeworm).
Taenia solium can also cause cysticercosis.

Clinical Features

Taenia saginata taeniasis produces only mild abdominal


symptoms.

Passage of proglottids.

Appendicitis or cholangitis can result from migrating


proglottids.

Development of cysticercosis.

Clinical Features

Asymptomatic

Abdominal discomfort

Human Cysticercosis superficial can be palpated

Brain infection
Personality change
Epilepsy
Encephalitis

Management & Prevention

Eradication of disease in animals

Meat should be properly cooked

Treatment is simple and very effective. Praziquantel* is


the drug of choice

50 mg / kg Tid for 10 days alon with Prednislone 10 mg Tid


for 14 days

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