FEU-NRMF Institute of Medicine

Pharmacology A S.Y. 2015-2016

Sympathetic Drugs Reviewer
Based on Dr. Zenaida Maglaya Lecture

b. Selective Beta 2 Agonists

Adrenergic Agonists

Direct Acting Agonists

I.

Mixed Alpha & Beta Agonists

II.

Alpha Agonists

Norepinephrine
Epinephrine

Phenylephrine
Midodrine
Methoxamine

b. Selective Alpha 2 Agonists

Methyldopa
Clonidine
Guanabenz
Guanfasine
Apraclonidine
Brimodine

c. Non Selective Alpha 1 and

Alpha 2 Agonists

III.

c. Non Selective B Agonists

a. Selective Alpha 1 Agonists

Naphazoline
Tetrahydrozoline
Oxymetazoline
Xylometazoline

Beta Agonists

a. Selective Beta 1 Agonists

Dobutamine
Prenalterol

Metaproterenol
Terbutaline
Albuterol (Salbutamol)
Isoetharine
Pilbuterol
Bitolterol
Fenoterol
Procaterol
Formoterol
Salmeterol
Ritrodine

Isoproterenol

Indirect Acting Agonists

I.

II.

Amphetamine-Like

Tyramine
Amphetamine
Methampethamine
Methylphenidate
Modafinil

Cathecolamine Reuptake
Inhibitors

Cocaine
Sibutramine
Duloxetine
Milnacipram
Atomoxetine

Mixed Acting Agonists

Ephedrine
Pseudoephedrine
Phenylpropanolamine

Dopamine Agonists

Fenoldopam
Bromocriptine

Adrenergic Antagonists

Alpha Antagonists/Blockers
I.

Selective Alpha 1 Antagonists

Prazosin
Terazosin
Doxazosin
Trimazosin
Alfuzosin
Bunazosin
Tamsulosin
Indoramin

II.

III.

Non Selective Alpha Antagonists

Phenoxybenzamine
Phentolamine
Ergot Alkaloids
Neuroleptic Drugs

Beta Antagonists/Blockers
I.

II.

*Non Selective Alpha and Beta Antagonists

Beta 1 Selective Blockers

Acebutolol
Atenolol
Bisoprolol
Esmolol
Metoprolol
Betaxolol
Celiprolol
Nebivolol

Non Selective Beta Blockers

Nadolol
Penbutolol
Pindolol
Propranolol
Timolol
Sotalol
Levobunolol

Labetalol
Carvedilol

**Beta Blockers with no distinct classifications

Selective Alpha 2 Antagonists

Yohimbine

Metipranolol
Carteolol
Carvedilol
Bucindolol
Labetalol

Bopindolol
Nipradilol
Bevantolol
Tilisolol

Adrenergic Transmission Drugs

Process
Transmitter
Synthesis
Transmitter Storage
Transmitter
Releases

SNS Drugs
Metyrosine

Reserpine
Bretylium,
Guanethidine

*These drugs are primarily classified as non

selective third generation beta antagonists
however since they can also block alpha 1
receptors, they can be secondarily classified as
non selective alpha and beta antagonists
**You can see these drugs under additional
cardiovascular action table in Wini Ong
transcribed notes. I looked at Goodman and
Gilman to find their distinct classification [if
they can selectively block a specific receptor or
none] unfortunately, it is not specified in the
book.
For simplicity, I didnt use the generation based
classification in beta antagonists. If you want
to know what is the generation of a specific beta
blocker, just look at Wini Ong transcribed notes

Hope this helps. Kindly message me for any

clarifications or corrections.
jbvb07 (ver. 2.0)