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Mitosis

Prophase:
Chromosomes shorten and thicken
Each chromosome is seen to consist of two
chromatids held by centromeres
Centrioles migrate to opposite poles of cell
Short microtubules radiate from centrioles
Nucleoli disappears
Spindle is formed
Metaphase
Chromosomes align at equator of spindle
Chromosomes attached by centromeres to their
spindle fibers
Anaphase
Such rapid phase
Centromeres split into two

Spindle fibers contract pulling daughter centromeres to


opposite poles

Sister chromatids pulled along by centromeres


Telophase
Chromatids reachpoles ofcell, uncoil ad lengthen to
from chromatic
Spindle fibers disintegrate
Centrioles replicate
Nuclear membrane re-forms around chromosomes,
nucleoli reappear

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