Name of Contraindicati Adverse Nursing

Action Indication
Drug on Effect Consideration

Generic: Cefuroxime It is effective for Hypersensitivity Body as a •Determine history of

Cefuroxime binds o one or the treatment of to Whole: hypersensitivity
more of the penicillinase- cephalosporins Thrombophlebi reactions to
Brand: penicillin- and related tis cephalosporins,
producingNeisse
binding antibiotics; (IV site); pain, penicillins, and
ria
Classificat proteins (PBPs) pregnancy burning,
gonorrhoea(PPN history
ion: which inhibits (category B),
cellulitis of allergies,
Antieffectiv the final G). lactation.
(IM site); particularly to drugs,
e; transpeptidatio Effectively superinfections before therapy is
Antibiotic; n step of treats , initiated.
Second peptidoglycan bone and joint
Generation synthesis in positive •Inspect IM and IV
infections, Coombs'
Cephalospo bacterial cell bronchitis, injection sites
rin wall, thus test. frequently for signs of
meningitis,
inhibiting GI:Diarrhea, phlebitis.
gonorrhea, otitis
biosynthesis nausea,
media, •Report onset of
and arresting
cell wall pharyngitis/tonsi antibiotic- loose
assembly lliti associated stools or diarrhea.
resulting in s, sinusitis, colitis. Although
bacterial cell lower pseudomembranous
Skin:Ra sh ,
death. respiratory tract colitis.
infections, skin pruritus,
•Monitor I&O rates
and urticaria.
and
soft tissue Urogenital: pattern: Especially
infections, Increased important in severely
urinary serum ill patients receiving
tract infections, creatinine and high doses. Report
and BUN, any
 is used for decreased significant changes
surgical creatinine
prophylaxis, clearance
reducing or
eliminating
infection.

Name of Contraindicati Adverse Nursing

Action Indication
Drug on Effect Consideration

Generic: Chemopreventi Prophylaxis and Use of sodium GI: Nausea, Assessment & Drug
Ascorbic ve action of treatment of ascorbate in vomiting,
patients on Effects
Acid vitamin C is scurvy heartburn,
attributed to sodium diarrhea. •Lab tests: Periodic
and as a dietary
Brand: two of its restriction; use Hematologic: Hct
supplement.
functions. It is of calcium Acute
Increases & Hgb, serum
Classificat a water-soluble ascorbate in hemolytic
ion: chain breaking protection patients anemia electrolytes.
Vitamins antioxidant. As mechanism of receiving (patients •Monitor for S&S of
an antioxidant, the digitalis. with deficiency acute hemolytic
it scavenges immune system, of
thus supporting Safety during anemia, sickle cell
free radicals G6PD); sickle
and reactive wound healing. pregnancy cell crisis.
oxygen Necessary for (category C) or crisis.
molecules, wound healing lactation is not CN S : Patient & Family
which are and established. Headache
Education
produced resistance to (high
Take large doses of
during infection doses).
metabolic Urogenital: vitamin
 pathways of Urethritis, C in divided amounts
detoxification. dysuria, because the body
The structure crystalluria uses
of ascorbic (high only what is needed
acid is doses). at a
reminiscent of Other: particular time and
glucose, from Mild soreness
excretes the rest in
which it is at
urine.
derived in the injection site;
majority of dizziness and
mammals. temporary •Megadoses can
faintness with interfere with
rapid
IV absorption of vitamin
administration. B12.

Note: Vitamin C
increases
theabsorption of iron
when takenat the
same time as iron-
rich

Name of Contraindicati Adverse Nursing

Action Indication
Drug on Effect Consideration

Generic: Due to To relieve mild Hypersensitivity Side effects Assessment & Drug
Paracetam paracetamol’s to to are Effects
ol structural moderate pain acetaminophen • Monitor for s/s of:
rare with
similarity to due or hepatotoxicity, even
aspirin, it has paracetamol
Brand: been assumed to things such phenacetin; use when with moderate
that as with alcohol it is taken at acetaminophen
Classificat paracetamol headache, doses, especially in
the
ion: acts by reducing muscle individuals with poor
production of recommended
Non-opiod and joint pain, doses. Skin nutrition.
prostaglandins,
Analgesic backache and Patient & Family
which are rashes, Education
involved in the period pains. It
blood • Do not take other
pain and fever is
disorders medications (e.g.,
processes, by also used to
bring and acute cold
inhibiting the
cyclooxygenase down a high inflammation preparations)
(COX) enzyme. temperature. of the containing
However, there For this reason, pancreas have acetaminophen
are important paracetamol can occasionally without medical
differences be occurred in advice; overdosing
between the and chronic use can
given to children people
effects of aspirin cause liver damage
and those of after taking the drug
vaccinations on and other toxic
paracetamol.
Prostaglandins to prevent post- effects.
a regular basis
participate in immunisation • Do not self-
for
the pyrexia (high medicate
a long time. children for pain more
inflammatory temp).
response, but One than 5 d without
Paracetamol is
paracetamol has advantage of consulting a
often included in
no appreciable cough, cold and paracetamol physician.
anti- flu over • Do not use for fever
inflammatory aspirin and persisting longer than
remedies.
action. 3 d, fever over 39.5°
NSAIDs
is that it C (103° F), or
doesn't recurrent fever.
irritate the
stomach or
causing it to
 bleed,
potential Side
effects of
aspirin
and NSAIDs.

Name of Contraindicati Adverse Nursing

Action Indication
Drug on Effect Consideration

Generic: It stimulates Shortens the Contraindicated Elevation of Avoid self

Immunosin the immune course of illness in patients with: serum and medication without
system by Gout consuting a
& reduces urine uric acid
Brand: inducing Renal disorders physician.
activation or severity of values which
Inosiplex Sever gastric
increasing symptoms of will return to
ulcers
activity of any respiratory normal of the
Classificatio of its
Pregnancy and
infections, lactation cessation of
n: components.
hepatitis A, drug
Immunostimul One notable
ant epidemic administration
example is the
granulocyte parotiditis, .
macrophage influenza A,
colony- German
stimulating measles,
factor.
infectious
mononucleosis,
measles, herpes
simplex, viral
encephalitis,
chickenpox,
 herpes zoster,
subacute
sclerosing
panencephalitis
(SSPE), CA.

Name of Contraindicati Adverse Nursing

Action Indication
Drug on Effect Consideration

Generic: • Inhibits the Treatment and Contraindicated CNS: • Assess patient for
Ranitidine action of prevention of in: Confusion, epigastric or
heartburn, acid dizziness, abdominal pain and
histamine at •Hypersensitivit
Brand: indigestion, and drowsiness, frank or occult blood
Zantac the H2 y, Cross- headache in the stool, emesis,
receptor site sour stomach. sensitivity may CV: or gastric aspirate.
Classificati located occur; some oral Arrhythmias • Nurse should know
on: primarily in liquids contain GI: that it may cause
Therapeutic gastric parietal alcohol and Altered taste, false-positive results
: black tongue, for urine protein; test
cells, resulting should be
Anti-ulcer constipation, with sulfosalicylic
agents in inhibition of avoided in dark stools, acid.
gastric acid patients with diarrhea, drug- • Inform patient that
Pharmacolo secretion. known induced it may cause
gic: • In addition, intolerance. hepatitis, drowsiness or
Histamine ranitidine nausea dizziness.
H2 GU: • Inform patient that
bismuth citrate Use Cautiously
antagonist Decreased increased fluid and
has some in: sperm count, fiber intake may
antibacterial • Renal impotence minimize
action against impairment ENDO: constipation.
H. pylori. • Geriatric Gynecomastia • Advise patient to
HEMAT: report onset of black,
patients (more
Agranulocytosi tarry stools; fever,
susceptible to s, Aplastic sore throat; diarrhea;
adverse CNS Anemia, dizziness; rash;
reactions) neutropenia, confusion; or
• Pregnancy or thrombocytope hallucinations to
Lactation nia health car
LOCAL: professional
Pain at IM site promptly.
MISC: • Inform patient that
Hypersensitivit medication may
y temporarily cause
stools and tongue to
appear gray black.