GENERIC BRAND DRUG CLASS DOSAGE AND HOW MECHANISM OF INDICATION CONTRAINDI SIDE - NURSING

NAME NAME FREQUENCY SUPPLIED ACTION CATION EFFECTS RESPONSIBILITIES

celecoxib Celebrex Pharmacologic 400 mg OD Capsules Exhibits anti- Adjunctive ● CNS: Before:
class: p.r.n inflammatory, treatment to Hypersensiti dizziness, - Assess pt’s
Nonsteroidal analgesic, decrease vity to drug, drowsiness, history of allergic
cyclooxygenase- and antipyretic the number sulfonamide headache, reaction to the
2 (COX-2 ) action due to of s, insomnia, drug
inhibitor, inhibition adenomatous or other fatigue - Monitor complete
anti- of the enzyme colorectal NSAIDs CV: blood count,
peripheral electrolyte
inflammatory COX-2 polyps in ● Severe
edema levels, creatinine
drug (NSAID) familial hepatic clearance, and
EENT:
Therapeutic adenomatous impairment occult fecal blood test
ophthalmic
class: polyposis ● History of and liver function
effects,
Antirheumatic asthma or tinnitus, test results every 6
Pregnancy risk urticaria to 12 months
pharyngitis,
category C ● Advanced rhinitis,
renal During:
sinusitis - Instruct patient to
disease GI: nausea, take drug with
● Late diarrhea, food or milk.
pregnancy constipation, - Teach patient to
● abdominal avoid aspirin and
Breastfeedi pain, other NSAIDs (such as
ng dyspepsia, ibuprofen and
flatulence, naproxen) during
dry mouth, therapy.
GI bleeding
GU: After:
menorrhagia - Advise patient to
Hematologic immediately report
: decreased bloody stools, blood in
vomit, or
hemoglobin
signs or symptoms of
or
liver damage
hematocrit, (nausea, fatigue,
eosinophilia, lethargy, pruritus,
epistaxis, yellowing
bruising, of eyes or skin,
tenderness on
upper right side of
abdomen, or flulike
symptoms).
SOURCE: NURSE’S DRUG GUDE 2008, SPRINGHOUSE