DRUG STUDY

Generic & Dose, strength & Indication/Mechanism of Adverse/side effects Nursing

Rationale Client Teaching
Brand Name formulation Action drug Interaction Responsibility
Ordered: Indication: Side Effects:
Generic: CEFUROXIME -Serious lower respiratory
250mg IVTT tract infection, UTI, skin CNS: dizziness, -Assess patient’s -To monitor drug’s • Advise patient to take oral
q8hrs or skin structure headache, insomnia, infection before effectiveness. suspension with food to
Cefuroxime infections, bone/ joint stroke therapy and enhance absorption.
infection, septicemia CV: hypertension, MI, regularly
Timing: meningitis and gonorrhea. peripheral edema thereafter. • Tell patient to report
Brand: q8 hrs. -Perioperative prevention EENT: Pharyngitis, adverse reactions.
Ceftin - Bacterial exacerbations rhinitis, sinusitis
Duration: of chronic bronchitis/ GI: Abdominal pain, -Before giving
immediate. secondary bacterial diarrhea, dyspepsia, the first dose, • Instruct patient to take drug
infection of acute flatulence, nausea, GI obtain specimen exactly as prescribed, even he
-To ensure right drug.
bronchitis bleeding for culture and feels better after
Other Form: -Acute bacterial METABOLIC: sensitivity test.
maxillary sinusitis Hyperchloremia, • Stress the importance of
Classification: Suspension: -Pharyngitis & tonsilities hypophosphatemia -Before giving taking the drug.
Second 125mg/5ml, 250 -Otits media MUSCULOSKETETA first dose, ask
generation mg/5 ml -Uncomplicated skin & L: patient about
-to avoid cross sensitivity • Maintain all of the usual
cephalosporin, Infusion ; 750 skin-structure infection Back pain previous
with other beta- activities and restrictions that
antibiotic mg, 1.5 -Uncomplicated UTI RESPIRATORY: reactions to
lactamantibiotics apply to your condition
premixed, frozen -Uncomplicated Upper respiratory tract cephalosporin
solution gonorrhea infection and penicillin.
Injection: 750 -Early lyme disease SKIN:
mg, 1.5. mg -Impetigo Erythema, multiforme,
exfoliative dermatitis, -Be alert for
Capsules; 50 mg, rash, Stevens- Johnson adverse reaction
100 mg, 200 mg, syndrome, toxic and drug -To establish proper
400 mg: epidermal necrolysis interaction. precautionary measures
MECHANISM OF and management for
ACTION; OTHER: possible adverse effects
Accidental injury of the drug.
Chemical effect: May
-If GI reactions
selectively inhibit COX 2 INTERACTIONS
occur,monitor
decreasing prostaglandin -To prevent dehydration .
patient’s
synthesis Drug-drug Diuretics ;
hydration.
may increase risk of
Therapeutic effect; adverse renal
Relieves pain & reactions . Monitor
inflammation in joints renal function closely.
and smooth muscle Probenecid: may inhibit
tissue. excretion & increase
level of cefuroxime.
Sometimes used for this
effect.
Drug-food: Any food:
May increase drug
adsorption &
bioavailability of
suspension. Give
suspension with food.
Tablets may begin
without regard to food.
-Before giving dose,
obtain specimen for
culture & sensitivity
tests. Begin therapy
pending test results.

-Before giving the first

dose, ask the pt. about
previous reactions to.
 DRUG STUDY

Generic & Dose, strength & Indication/Mechanism of Adverse/side effects Nursing

Rationale Client Teaching
Brand Name formulation Action drug Interaction Responsibility
Ordered: Indications: Adverse reaction: Assessment:
Generic:
50 mg slow IVTT CNS: Light -assess patient for -to take an early actions of -inform patient that drug can
Ranitidine -Intractable duodenal headedness, epigastric or abdominal signs of internalbleeding. cause drowsiness and
ulcer; pathologic dizziness, insomnia, pain and frank or occult dizziness.
hypersecretory confusion, blood in the stool,
Brand: conditions, irritability,psychosis, emesis or gastric
-Duodenal and gastric ataxia, depression, aspirate.
Zantac Timing: ulcer hallucination. -instruct to report any
-Maintenance therapy for -Assess pt.’s. GI adverse reaction occurs.
Classification: duodenal ulcer -CV: CHF, orthostatic condition before -to monitor the drug
q8
Pharmacologic -Gastroesophageal hypotension, starting therapy and effectiveness.
class: -Reflux disease dyspnea. Regularly thereafter to
H2 –receptor Duration: -Erosive esophagitis monitor drug’s -encourage patient to
antagonist -Self-medication for -GI: Nausea,anorexia, effectiveness increase oral fluid intake
occasional heartburn, constipation, dry . and fibers to prevent or
Therapeutic -acid indigestion and mouth. *Be alert for adverse minimize constipation.
class: ther forms: sour stomach -GU: Urinary reactions and drug inter
Antiulcerative retention action. -to establish proper
O 12.5 mg TIV q Mechanism of action: precautionary measures and -inform patient that this
management for possible medication can cause
12 hrs Inhibits the action of the *asses patient’s and adverse effects of the drug. temporary grey black color
histamine at H2 receptor family’s knowledge of of tongue and stool.
site located primarily in drug therapy. - To check the patient and the
gastric parietal cells, in Family’s level of
resulting in inhibition of -Do not discontinue understanding about the drug. -encourage patient to have a
gastric acid secretion. abruptly when regular check up.
treating
parkinsonism
syndrome,
parkinsonian crisis -it might cause other
may occur. complications.
 DRUG STUDY

Indication/Mechanis
Generic & Dose, strength & Adverse/side effects Nursing
m of Rationale Client Teaching
Brand Name formulation drug Interaction Responsibility
Action
Ordered:] Indications: Adverse reaction: Assessment:
Generic:
Chronic constipation, Bloating; faintness; -Auscultate bowel sounds -.By checking frequency &
Bisacodyl preparation for nausea; rectal at least once per shift. characteristic of stools. >.Advise patient to swallow
Dulcolax rectal surgery/rectal/bowel irritation; stomach -.Obtain history of bowel enteric-coated tablet whole to
suppository 10 examination fullness, cramps, or disorder, GI status, fluid -Check for pain and cramping avoid GI irritation.
mg adult, 2 discomfort; vomiting. intake, nutritional status, and to know the condition of
Brand: suppositories per Mechanism of action: exercise habits & normal the patient >Advise patient to report
rectum patterns of eliminations. adverse effects to prescriber.
. Bisacodyl works by
dulcolax Timing: stimulating enteric Drug interactions: -Be alert for adverse >Warn patient against excessive
nerves to cause reactions and drug inter use of drugs.
Classification: HS(8pm) colonic mass . May cause gastric action -to establish proper >Teach patient about dietary
movements. It is also irritation or dyspnea precautionary measures and sources of fiber, including bran
Stimulant Duration: a contact laxative; it from premature management for possible and other cereals use of drugs..
laxative increases fluid and dissolution of enteric adverse effects of the drug.
NaCl secretion coating. avoid use -Assess for baseline data >teach patient the proper storage
Other forms:
(lippicott & wilkins together --to indicate baseline data and of the medication.
2009 Ed. ;213) monitor drug’s effectiveness.
Enema: 10mg/30
-To prepare the patient for any
ml
side effect.
Tablet(delayed-
release): 10 mg
Tablets(enteric-
coated
 DRUG STUDY

GENERIC/BRA DOSE, INDICATION/ ADVERSE/SIDE NURSING RATIONALE CLIENT TEACHING

ND NAME & STRENGTH & EFFECTS DRUG RESPONSIBILITIES
CLASSIFICATI FORMULATIO MECHANISM INTERACTION
ON N OF DRUG
ACTION

Generic: Ordered: Indications: Adverse/Side Effects: Assessment: *Teach patient to recognize and
immediately report signs and
Ketorolac >Short-term CNS:dizziness, 1. Assess patient’s pain before -To monitor drug’s symptoms of GI bleeding.
Tromethamine management of and after drug therapy. effectiveness.
pain drowsiness, *Advise patient to report
persistent or worsening pain.
headache,
2. Be alert for adverse -To avoid severe adverse *Explain that drug is intended
Timing: insomnia, reactions and drug effects. only for short term use.
interactions.
Mechanism of CV:edema, *Take drug as prescribed by the
Brand: Action: hypertension, Planning & Implementation: physician.
Duration: palpitations
*May inhibit 3. Drug may cause peptic *Tell patient not to exceed to the
6-8 hours prostaglandin EENT:transient ulcers, GI bleeding, or prescribed amount.
synthesis stinging and burning perforation of the stomach and
Available Forms: intestine. -Monitor patient closely.
*Relieves pain GI:diarrhea,
Injection:15 and dyspepsia, GI pain, 4. List all the medication the
Classification: mg/ml,30 mg/ml inflammation nausea patient is taking.
-To prevent drug interaction.
• NSAID Opthalmic GU:hematuria, 5. Apply pressure to injection
• Analgesi Solution:0.4% , polyuria, renal failure site for 15-30 seconds after -To minimize local effects.
cs, anti- 0.5% injection.
inflamm Hematologic:
atory Tablets:10 mg
anemia, eosinophilia,
purpura
Skin:sweating

Other:pain at
injection site.

Drug Interaction:

Drug-Drug. Anti-
hypertensive,
diuretics:May
decrease
effectiveness of these
drugs. Monitor
reactions closely.

Lithium:May increase
lithium level.

Warfarin:May
increase levels of free
salicylates or
warfarin in blood.

Methotrexate:

May decrease
methotrexate
clearance and
increase toxicity.