Professional Documents
Culture Documents
Form 1 Section 1
NBME
Form 1 Section 2
NBME
Form 1 Section 3
NBME
Form 1 Section 4
NBME form 4-‐1
NBME form 6-‐1
Form 6-‐2
Form 6-‐3
Form 6-‐4
NBME form 5 ʹ 1
NBME Form 5-‐2
NBME Form 5-‐3
NBME form 5-‐4
NBME form 4-‐2
NBME form 4-‐3
N B M E form 4-4
Block 1
1... zinc finger motif is a D N A binding domain for steriod receptor so A is right answer
2 M c A rdle disease G lycogen is there in the ms but cant be used bec. of deficievy of G lycogen phospholylase enzyme
3- Discuss
4- T ight junction are present between the cells and when they are damaged the + discussion
5- C F is A R disease ... the child with diease is homozygous for C F gene.. car rier are heterogygous for the mutation...
For the parent to produce a homozygous child they must both be car rier of the C F . discuss
6- W e are transplanting gene in the bone mar row so is cant be structural gene and the probable answer could be B
7- here its cant be sarcoma becasue vimentin antibodies reaction are negative... only clue is keratin antibodies as in
squamous cell ca there is keratin pearls so E seem to be right
9-He is without food from the last one week... note he consumed his food in the first two weeks. A is wrong as no diet
is there hepatic glycogen store are for the first few hours.skeletal muscle glycogen cant be used because of abscence of
glucose 6 phosphatase enzyme in muscle D is the cor rect answer .. muscle protein are being used by the
gluconeogenesis process urea nitrogen cant help
10- D is the cor rect 11-Bleomycin causes pulmonary fibrosis mean a restrictive lung disease in restrictive lung diease
either there is increase in F E V1/F V C ratio or there is no change in it..... total lung volume decrease as there is
restriction in filling the lungs to there capacity please add what will be the effect of diffusing capacity C is the answer
13- urease is the answer but what is the substrate of urease and what the product??
16-this is acute rejection as occur after weeks of transplantations... so T lymphocyte play there role
17-need explanations
18 need explanations
19-T N F is produced in response to E ndotoxin and then T N F causes release of N O which is the main mediator of
shock and hypotension
20-D dimer are specific for D I C , D dimer can only assay the cross linked fibrin monomer while F DP assay detect all
the product of plasmin cleave of fibrenogen and insloluble fibrin clots
24- B is right D M causes accumulation of sorbitol in the schwann cell becuase of A L D OSE R E D U C T ASE E N Z Y M E
which convert glucose into sorbitol and lead to osmotic damage to the shwaan cell and defective myelination of
peripheral nerve and so peripheral neuropathy..........
28-iliopsoas
30-B
31-case of asthma which is an obstructive lung diseas F E V1. F V C is typically decreased and residual volume is
increased
32-superior vena cava syndrome due to small cell lung carcinoma causeing obstruction of the vena cava and so
puffiness of the face and neck
33- Patent ductus arterosis connecting aorta with left pulmonary vein
34-as we are increasing the precapillary resistance when flow will dec and the filtration will decrease .... 35-Beta 1
increase renin secretion but alpha 1 decrease renin secretion.
36...
37 J
39-Did you noticed that when we add the drug X we need more histamine to get the same response mean there is a
revercible competitive inhibitor there
40- its 30
42- becuase there are bruit its mean there is atherosclerosis of the renal artery .. less blood goes to the kidney and
renin is secreted which convert Ag1 into Ag 2 and which in turn increases ald. and increase Na absortion and so H T N.
45-B
47-W e know that radiation induced thyroid papillary ca is most common but can it be L aryngeal C A????
BLOCK TWO
1-B seem to be right... when we add antibiotic resistance plasmid, we can get the colonies who are resistance to a
particular drug and can eliminate the drug that are sensitive ...
2- C seem to be right as we see that in C F there is a defect mutation and 508 codon is missing coding for
Phenylalanine amino acid .. in C only phenylalanine is shown there
6-X linked recessive disease more common in male and if female are symptomatic then its because of inactivation of
more maternal chromsome than paternal... female are homozygouys for the abnormal chromosome.
7-A
9-here is a point never assist the patient to die .... passively is ok but actively is not ok.... i think C seem to be right
10-D??
11-E
13-A
15-B
16-D because IgG protect respiratory mucosa from infection 17-listen steven daughtery
19-see physio
20-A
21-polycythemia so F
23-Radial nevre
24-circle of willus
25-D should know from where various seizure arise in the brain
29-G
33-C
34-During exercise the heart rate increases and when H R reach 180 it compromise the coronary blood supply .. O K
now pumping action increases the heart metabolism and increases metabolite causes coronary vasodilation..... and so
increases blood flow. Now in exercise increase wor k volume occur at same pressure so C seem to be right
35- Aortic pressure will be less than ventricular pressure so D seem to be right
39-F
40-c
42-F
43-B
46-E
48-D
49-C seem to be right ... physiostigmine enter C NS , neostigmine not so when you have confusion about which enter
then think N is for N O T ..
50- C
BLOCK 3
1- A/T rich region are where H istone bind to D N A, Nucleosome are formed by the histone octamer plus D N A wound
round it. O ne nucleosome is connected to the other by H1 histone. Need net search or discussion..
7-G amma interferon secreted by T h1 cell causes M acrophages activation and activated macrophages become fused
to form multinucleated giant cell
8-A
10-V it. C
11-E
12-A
15-discussion
17-this is a bar graph ok first you count how many are total children so 25+30+35+10=100 now how many children
have two episode of U T I? answer 10 now out of hundred children 10 have two episode of U T I and will be be 10
percent .
19-A
20-Aferican type of Bur kit lymphoma classic picture of star ry sky appearance associated with c myc oncongene..
21-B
22-F
23-A
24-E
25-D
26-C
28-Posterior cruciate ligament T ibia move posterioly while for anterior cruciate ligament tibia move anteriorly
30-A???
32-Pneumothorax there will be H yper resonant, deviation of tracha to opposite plus decreased breath sound and
absent fremitus
33-A
34-A
35-B
37-C
41- A D H causes increase water reabsorption so serum osmolarity would Dec , U rine osmolarity inc and urine sodium
conc will be high
45 Cervical
55 endometrial
65 O varians Note C E O alphabat come accordingly in the Q stem ist mention that she has P C OS mean has high
estrogen plus H eight is normal mean she dont have tuner syndrome which point to ovarian syndrome ... but its
endometrial C a post menopausal bleeding
45-E
46-D PI D
47-B
49-need discussion
BLOCK 4
1-A
5-its X linked recessive mean only diease gene on X chromosome and if that male parent would have defective gene
on his X chromosome then he would have the disease and he dont have its mean that he is not car rier of this disease
6-B
8-B??
10-Partial agonist as at low dose its acting as agonist but at high dose its acting as antagonist.
11-A
12-Penecillin excreted by kid. so when renal function are compromised then sr. drug level increse as this y patient
13-D
14-B
15-E
19-E
21-A
23-E
25-E
27-B
29-need to discuss A?
30-H
31-E 32-G D V T
33-E
34-D
36-A
38-cir rhosis and increase in splenic vein pressure due to portal hypertension
41-C
43-B because for outlet incontenence there is continouse voiding without a stress factor
44-5 alpha reductase convert testosterone into D H T which is necessary for the development of external ganitalia
including prostate when D H T is not formed female external feature are formed but internal male system is
developed because testosterone is required to form normal internal male struture .
45-E
49-C
NBME
Form 3 Section 1
NBME
Form 3 Section 2
NBME
Form 3 Section 3
NBME
Form 3 Section 4
NBME
Form 2 Section 1
NBME
Form 2 Section 2
NBME
Form 2 Section 3
NBME
Form 2 Section 4