ee a a ¥ ‘noge eumonis ety uo pam ‘a pUE y 'sdnoI6 uoTaUN} omy ay AWN (A) Ne) 1uojeq uous 8 pe oY unde jo exneyUEW ot 10, wuurdse wl ws 1d ons jo ayduexe aug “a1uNoO a4) J810 SHES iu) ued enanss of pesonpoxd aq 1ouUeD suudlopuS, use Suyce-sey Ang am 08 puw la ‘sopyded woh uy fq wusous oy rEK UID Ce) “a Jo posed Bue se wjed a ado oF ane Saino 4370 uel ufeiq tn 0 pre ayy} aus99 Kel SUE JNO UI PUNE} SopHAG BIE SURyEIODU z J9n0 wan} cep su ey eee seuss BPE “safiod pojuud 91, 30 116009 Joded uonsonb Sm. a6 [wan ° ale s |e “sume fe uses x ye aso Fee eet ciel (yg) Aaeuso4g 0) 004 aA ‘otsanb an ‘yen | ven | no] wo oURuWOD Ueno AE gen sumwimwxa wos | yoes jo pus oy 2 [J sioypeNR UL UAKS = SHFEL JO 220 SAIVOIONVO HO NOLIVIHOANI amok Bure ascyeq op oF ony NOK EU Mou NOK auns eeu UR ede uojsenb au wo seaeds ‘enoge sex0q aig U eqUunU aWePIpUED pu Seq eH “arog eoeds ain U ‘SAIVGIONYD 01 SNOLLONELSN ‘erin 9¢ roy} SNA ny AT rene ser es) uc sto 1oded open gw lowes semqucesnoy} ——eooumy og ANRGL ——_AesepoN pais pur sueoig siushog esez (Sears) AMLSINaHO 399 pooteapy SNouWNInyxa Yeu aN 3DaIuaHWvo GUOXO3 acl, (©) Draw te: A sold sample of aspirin prepared using this method was found tobe impure, 9) Name the technique you would use to puly the sample (0) How would you determine whether the sample is pure? mula ofthe acy chloride you would use inthis reaction Aspirin ean be prepared inthe laboratory by the reaction of an acyl chloride with ealoyto | Be tt] i (Turn over iL ot wintergreon is aleo a paikiter onde sold asa cream to be applied diecly tot skin. ean be made by heating slleyic acid under reflux with an alcohol and a suitable catalyst. (©) (Complete the equation below to show the structural formula of the alcohol you ‘woud use and the formula ofthe other produe formed. i bi So — ry ef od. |_ | saboylie ac aleohot ilof wintergreen other product a (i) Name a sutabi catalyst for reaction. Clot wintergraen can be hytrlyoed to give two products (9. Complete the equation below to show the structure ofthe produets formed when ol ot \wintorgreen is hydrolysed with aqueous sodum hydroxce. oa) product ¥ product Z[i uoneounaniog usiuya Jo Aeon wre gerd ‘01 puog 01 | shoe e9eq eujuent Wj uo Woye UaBOAIL yl Jo aune UM (D () 3 088 euten fe Sous asouL, jooueo-nU eu ‘vognyos ouyes waged ou oy van 5! upetcsp Ayr ysefiGns 0 LogeUORY SHA e8n) (0) (2puowp upos jo uonennsav0. YB feaner 2 Suuuewoo uouryes snoonbe we) uoUNos Sues ul waned au o1 VAAN s UNEIGES oy. Oz + OPH CN) = ONE + Pro*FHNNal “sisi wunuquinbe Suymojoy on 19H" y sax)ossIP UNICO HOUR “Awoe sooueo- nue ssass0d (I)kunUNEd JO saxeydui09 poBLeYauN ax AUD soo win) aia uy ‘equine uoseupiccn exp ih xoPiuoo Bo adoys ojqSH0d JOY AR BIAS (I) ur fio Nc] yo soqunu woteip2000 ox 3 EUNK, ur EOE Eot eit Nha K@ umoys wovewoejo ody ou wR (N) fa “stows! aqssod ou mei) “un guowoe: ony wy 39041 1eUR}d 0b of oF ene xaCNCD a4, (4) sojctuco wen ay) fa wou 6 Tous ney (2) ‘onal xerun9 ow suTIUOD UNIO -voqovas o8usyox9 pu © yBnosse YO 61 8PUNq “Yop sour} BupvaNO:d S00 eOUeD ‘BUpIA vt YG oF Buu Aq ae of PENdHOG 6 "Brup JB0UED-qu ryssEOONS 8) UNAS aCarboplatin contains the following ligand, L Carboplatin nas a simar strcture fo cisplatin, but with ligand L replacing the two chloride ganas. (6) Draw the structure of carboplatin below showing how ligand L. bonds to the platinum on. 1 (0, What name is oven to a ligand, such as igand L, that has two points of attachment to the mela on? veel {otal 20) a Tum over , ba Captain has been tound to have toe side effects, so alternative compounds are being | 3 Investigated. One of these Is called carboplatin. | 1 ‘When archasologits were excavating @ Viking sattenent in Copporgnt, York, tha ‘Sscovered an almost prec preserved Angin helmet. ea 7 ‘The ground in which the feimet was bured was completly waterlogged which meant that the parts of the heimet made from iton had eorcoded very slowly. When te helmet was excavated it began to corrode very quickly. (2) Suggest why corrosion of he helmot underground had taken place very slowly. 1) (0) The fest stage of rusng Is an etcrcherical process ivohing the folowing ha seustons Fo(ac) + 2° 5 Fale) Ene ration t Ox) + 2H00 + dor —+ 40H (aq) 24040 reation2 (0) ete an overall equation fr to fst ino of to rsting roece. i) Calesate E. forthe overall eactionin (6). std (il) Suggest formuta for rust and explain how it is fonned from the product of the reaction i (BK.a mo}oq Bunpow snOK MOUS ‘spuodas ppd) Jou ean LOADED! 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B cwEL jo LoREUNOH UP Jo S209 Butlog fq Gusts W304 paroanod are ‘epHOND wnpos panjossip Jo eouBseid BAL “epHOW Lunypos DaNOsSH SUIEIIOD Heyem 9S even 98 Aq popuneins exe suoddns \2es eM se sDu 1040) WO,AOIG B OB 8 BUEN ourey ou jo deo ™ oidoup 90m roway 24 Jo aompns oun w Hoy UodDOIS 19 Jo UOREOHP OU og MojOR LHEIBEIP OH HS el meee yy UoTOMDS OH ‘ye vonenbesieH, ‘wolea Weide ou Uo g pu ye SuuINaco suoROEAL AiR 20} LoRENDEHHEU eHBOND (0) wap ai punose wapinD Ayejoqved sex yrs ‘uogenzaxe Joyy “dco ou UN Wop ofse|v aney 0 pund) Sn usoy‘amount of H,, remsining/x 10% mal " fe (0 Pita graph ofthe amount of hydrogen poroxide temalning in 1Dem? of reaction misture against time on he gid Beton. 0 190 200 960 400 560 600 700 90 900 1600 tina’ ‘si the 4) How dows your graph confi that the reaction is fst orcer with rap ‘concentration of Fydrogen peroxide? Show cearly haw you artved at your sone Ina separate set of experiments, the students found thatthe order of reaction with respect to tho catalyst was 26r0, (©) (Wie the ate equation forthe reaction, sence (i) The ate is measured in molds. Work out the unite of the rate constant, snowing your working. Units of ate constant Penn secs (otal: uct tit ver "800 1400 1500 1600 1700 1600 1900 ‘Amphstamines aro synthete chemicals which can act as stimulants. ‘The fist amphetamine to be markoted vas called Benzedrina, which was used in World War to enable eolcors to stay awako fr long periods of tie. “The structure of Bonzecrine is shown below. ons Bonzedrine (2) raw an astorick() next to the chiral earbon atom on the etuctire of Berzedtine, [1] ‘A more potent form ofthe drugis ts mor image Dexectine. (©) Draw the 3clmensional stuctures of Benzedrine an its miro image Dexedrine. (You do not need fo label wich i whic). a ‘The structures of amphotamines resemble that of noradrenaline. Novadrenaline is a ‘moiacuie made in our todtes that affects blood pressure. ‘The structure of noradrenaline is shown below. “or8 (©) () Name the functional group ccleg on noradrenaline, Att)‘ouiod » 0 yBuans apse, ay s99s0.5u1 Bum pos Ap we ‘Bwyveip ps0 payed I spuers cll ousjod a4 BUM Jo sseC01d Bu. Ce) ‘mojea unoys | 9'9-LO/u Jo UEuD Z0WKod B Jo We "sanqy Supnpoad 1) snjoq es os pu sioaied oxy URKA simaredusy Buyous JOYE © pUE ‘yBvans o1sve. Ize e Pey UO} ay. 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(lew Lae y} " aA Inialy Stary! was rejected because its molecusr mass was considered to be 100 low. Haweter, Siany/has eeoantly been produced with a molecular mass in the region of 30000. Stanylhas a greater tensile Strengl and melts ata higher temperature than nyion-8.6 (€) (@ Stany! metts at a bigher temperature than nylon-66. Explain wy this is 60. (You ‘ay assume that the polymer chans have a similar 8) (ji) How many repeating units would you expect to bo prosent in polymer chan ot Stany/ot M3200? Ta c12, HA; Nes 0.16) store Tum over ‘ovar isa fre resistant material, which is also much stronger than nylon, The strength of ‘Kevlar is one property which makes it sutable forthe replacement of steel cord in tyros. ‘Revlarbelongs toa family of polyamides called aramid. +O1O-+ {(@) Suggest throe other usstul propertise of Kevlar hich arse from is structure ait BE produce a specie! typs of sik to support their webs. Scientists have discovered that 15, weight for weight stongor tran Kolar ‘Scientists have isolated the gone responsile for making ths sik Thay inserted this gane Into E cof bacteria, The bacteria then produced the sik. (©) Outine the stages in the genetic engineerng technique that allowed sclontsts to transfer the gene and so use Ecol bacteria as an artical spider. smell otal: 181 Saar ‘coming Prac lon ant ead ei Cn Si Yo Acne et