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Works Cited Barak, Yorama, et al. "Affective psychosis following Accutane (isotretinoin) treatment .

" International Clinical Psychopharmacology 20.1 (2005): 39-41. International Clinical Psychopharmacology. Web. 18 Oct. 2011. This source describes of cases of 500 soldiers evaluated in a military specialists dermatology clinic for severe acne. The paper describes manic psychosis that developed during isotretinoin treatment and resulted in suicidality and examines risk factors of the drug. "Brain imaging studies suggest a link between Accutane and depression." Brown University Psychopharmacology Update 17.2 (2006): 3. Academic Search Complete. Web. 19 Oct. 2011. This source outlines a study conducted by Dr. J. Douglas Bremner provides evidence for a link between Accutane use and depression by suggesting that the drug causes changes in brain functioning associated with depression.

Ferguson, Sherry, et al. "Oral treatment with ACCUTANEdoes not increase measures of anhedonia or depression in rats." Neurotoxicology & Teratology 29.6 (2007): 642-651. Academic Search Complete. EBSCO. Web. 18 Oct. 2011. This source outlines the findings of a study of the effects of isotretinoin in rats. The study cites previous results and suggests that Accutane does not produce behavioral alterations indicative of depression in rats.

"Improved quality of life with isotretinoin (Accutane)." Brown University Child & Adolescent Psychopharmacology Update 11.3 (2009): 8. Academic Search Complete. EBSCO. Web. 18 Oct. 2011. The source summarizes the findings of a Brown University study on Accutane. The study found significant improvements in quality of life, depression and anxiety in patients with acne treated with Accutane as compared with topical acne therapy. Kern, Daniel. "Accutane / Roaccutane - Isotretinoin ." Acne.org. N.p., n.d. Web. 18 Oct. 2011. <www.acne.org/accutane.html>. This source provides an up to date report on the drug Accutane and its side effects. The website contains very detailed information on this drug and supports all of its points with citations.

Sundstrm, Anders. "Association of suicide attempts with acne and treatment with isotretinoin: retrospective Swedish cohort study." BMJ 341.5812 (2010): n. pag. BMJ. Web. 18 Oct. 2011. In this source, Sundstrm aims to assess suicide risk before, during and after isotretinoin treatment and patients with severe acne may be at higher risk of attempted suicide regardless of exposure to the drug.

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