MODULE 1 MULTIPLE CHOICE QUESTIONS

Problem 1: Complementary bases

For the DNA strand 5'-TACGATCATAT-3' the correct complementary DNA strand is: A 3'-TACGATCATAT-5' B 3'-ATGCTAGTATA-5' C 3'-AUGCUAGUAUA-5' D 3'-GCATATACGCG-5' E 3'-TATACTAGCAT-5'

Problem 2: The replication fork

In this diagram of the process of DNA replication at a replication fork, the strand labeled B is the:

A template strand B lagging strand C leading strand D Okazaki fragment E RNA primer

Problem 3: The replication fork

In this diagram of the process of DNA replication at a replication fork, the newly synthesized DNA strand labeled C is the:

A coding strand

B parental DNA C leading strand D lagging strand

Problem 4: More on the replication fork

In this diagram of the process of DNA replication at a replication fork, the black boxes labeled D and E are:

A RNA primers

B DNA template strands C Okazaki fragments D DNA polymerase

E Newly synthesized DNA strand

Problem 5: Problems on transcription

Three types of RNA involved in comprising the structural and functional core for protein synthesis, serving as a template for translation, and transporting amino acid, respectively, are:

A mRNA, tRNA, rRNA B rRNA, tRNA, mRNA C tRNA, mRNA, rRNA D tRNA, rRNA, mRNA E rRNA, mRNA ,tRNA

Problem 6: Protein amino acids from translated mRNA

A messenger acid is 336 nucleotides long, including the initiator and termination codons. The number of amino acids in the protein translated from this mRNA is:

A 999 B 630 C 330 D 111 E 110

Problem 7: mRNA and protein coding

Under conditions where methionine must be the first amino acid, what protein would be coded for by the following mRNA?

5'-CCUCAUAUGCGCCAUUAUAAGUGACACACA-3'

A. B. C. D. E.

pro his met arg his tyr lys cys his thr met arg his tyr lys cys his thr met arg his tyr lys met pro his met arg his tyr lys cys his thr arg his ser glu tyr tyr arg leu tyr ser

Problem 7: mRNA polypeptide code

Which mRNA codes for the following polypeptide?

met arg ser leu glu

A. B. C. D. E.

3'-AUGCGUAGCUUGGAGUGA-5' 3'-AGUGAGGUUCGAUGCGUA-5' 5'-AUGCGUAGCUUGGAGUGG-3' 1'-AUGCGUAGCUUGGAGUGA-3' 3'-AUGCGUAGCUUGGAGUGA-1'

Problem 8: Codon-anticodon base pairing

With what mRNA codon would the tRNA in the diagram be able to form a codon-anticodon base pairing interaction?

A. B. C. D. E.

3'-AUG-5' 3'-GUA-5' 3'-CAU-5' 3'-UAC-5' 3'-UAG-5'