Generic Name, Trade Name & Form of Drug

Tramadol + Paracetamol (Dolcet)

Date Ordered

Classification

Dose/Frequency

Mechanism of Action

Indications

Contraindications

Adverse Reactions

Nursing Responsibilities
1 .Assess onset, type, location, and duration of pain. 2. Effect of medication is reduced if full pain recurs before next dose. 3. Review past medical history, especially epilepsy or seizures. 4. Give without regards to meals. 5. Monitor pulse and blood pressure. 6. Assist with ambulation if dizziness or vertigo occurs. 7. Dry crackers or cola may relieve nausea. 8. Assess for

12/28/11

Analgesic

1 tab TID 6-12-6

Tramadol binds to opiate receptors and inhibits reuptake of norepinephrin e and serotonin. It reduces intensity of pain stimuli incoming from sensory nerve endings, altering pain perception and emotional response to pain.

Moderate to severe pain

Acute intoxication with alcohol, hypnotics, narcotics, centrallyacting analgesics,opioids or psychotropic drugs. Hypersensitivity

CNS & GI disturbances. Nausea, dizziness, somnolence. Asthenia, fatigue, hot flushes, constipation, diarrhea, flatulence, dry mouth, pruritus, increased sweating, tinnitus

clinical improvement and record onset of relief from pain.

Generic Name, Date Trade Name Ordered & Form of Drug

Moxifloxacin (Avelox) 12/28/11

Classification

Dose/Frequency

Mechanism of Action

Indications

Contraindications

Adverse Reactions

Nursing Responsibilities
Observe 10 rights in giving medications.

Macrolides Anti-infectives

400mg 1 tab OD

Moxifloxacin has in vitro activity against a wide range of Grampositive and Gram-negative microorganisms. The bactericidal action of moxifloxacin results from inhibition of the topoisomerase II (DNA gyrase) and topoisomerase IV required for bacterial DNA replication, transcription, repair, and recombination. It appears that the C8-methoxy moiety contributes to

Treatment of upper & lower respiratory tract infections e.g. community acquired pneumonia

Hypersensitivity to quinolones.

Nausea Vomiting Abdomina l Pain Headache

enhanced activity and lower selection of resistant mutants of Gram-positive bacteria compared to the C8-H moiety. The presence of the bulky bicycloamine substituent at the C-7 position prevents active efflux, associated with the NorA or pmrA genes seen in certain Gram-positive bacteria.

Generic Name, Trade Name & Form of Drug

Clindamycin (Indamix)

Date Ordered

Classification

Dose/Frequency

Mechanism of Action

Indications

Contraindications

Adverse Reactions

Nursing Responsibilities
1. be alert for adverse reactions and drug interactions

12/29/11

Antibiotic

300 mg 1 capsule every 6 hrs.

- inhibits bacterial protein synthesis by binding to 50S unit of ribosome - hinders or kill susceptible

Infections caused by sensitive staphylococ ci, strepcocci, pneumococc i, bacteroides, fusibacteriu

Contraindicated in patients hypersensitive to drug or lincomycin - use cautiously in patients with renal or hepatic disease,

CNS: headache CV: Thrombop hlebitis EENT: pharyngiti s GI: abdominal

bacteria

m, clostridium perfringens, and other sensitive aerobic and anaerobic organisms, pneumocysti s pneumonia

asthma, history of GI disease, or significant allergies

pain, Anorexia, bloody or tarry stools, constipati on, diarrhea, dysphagia, esophagiti s, flatulence, nausea, ps eudomem branuscoli tis, unpleasant or bitter taste,vomi ting. GU: UTI HEMATO LOGIC: Eosinophil ia, thrombocy topenia, transient leukopeni a SKIN: maculopa pular rash, urticaria

Generic Name, Trade Name & Form of Drug

Celecoxib (Celebrex)

Date Ordered

Classification

Dose/Frequency

Mechanism of Action

Indications

Contraindications

Adverse Reactions

Nursing Responsibilities
1. May give without regard to food. 2. Assess onset, type, location, and duration of pain or inflammation. 3. Do not crush or break capsules. 4. Evaluate for therapeutic response: relief of pain, decreased stiffness, swelling, increased joint mobility, decreased tenderness, and improved grip strength.

12/28/11

Nonsteroidal Antiinflammatory Drugs (NSAIDs)

200 mg 1 cap BID 8-8

Celecoxib inhibits cyclooxygenase-2, an enzyme responsible for producing prostagladin which causes pain and inflammation. It produces antiinflammatory effect.

Management of acute pain

Allergy to NSAIDs. Patients with allergic reactions to NSAIDs

GI discomfort , nausea & diarrhea

Generic Name, Trade Name & Form of Drug

Myrin-P Forte

Date Ordered

Classification

Dose/Frequency

Mechanism of Action

Indications

Contraindications

Adverse Reactions

Nursing Responsibilities
Observe 10 rights of giving medications

1/1/2012

Anti-TB Agents

3 tabs OD

The mechanism of action of ethambutol is not fully known. It diffuses into mycobacteria and appears to suppress multiplication by interfering with RNA synthesis. It is effective only against mycobacteria that are actively dividing. Rifampicin inhibits bacterial RNA synthesis by bonding strongly to the -subunit of DNAdependent

Initial phase treatment & re-treatment of all forms of TB in category I & II patients caused by susceptible strains of mycobacteri a

Alcoholism, optic neuritis, impaired hepatic function, severe renal insufficiency, hyperuricemia, gouty arthritis, jaundice, retrobulbar neuritis. Pregnancy and Lactation.

Disorders of the blood & lymphatic system, immune system, metabolism & nutrition, CNS, eye, GI, hepatobiliary, skin tissues, musculoskeletal, connective tissue & bone, renal/urinary, reproductive system & breast. Fever, malaise, flu-like syndrome, dryness of mouth.

RNA polymerase, preventing the attachment of the enzyme to DNA and thus, blocking initiation of RNA transcription. Isoniazid is a bactericidal antitubercular agent, which is active against actively dividing mycobacteria, and its mode of action may relate to inhibition of mycolic acid synthesis and the disruption of the cell wall in susceptible organisms. The mechanism of action of pyrazinamide

is unknown. Pyrazinamide may be bacteriostatic or bactericidal depending on its concentration and the susceptibility of the organism.

Generic Name, Trade Name & Form of Drug

Omeprazole (Losec)

Date Ordered

Classification

Dose/Frequency

Mechanism of Action
Omeprazole is converted to active metabolites that irreversibly bind and inhibit H+-K+ATPase (an enzyme on the surface of gastric parietal cells). It inhibits transport of hydrogen ions

Indications

Contraindications

Adverse Reactions

Nursing Responsibilities

1/1/2012

Antacid

40mg 1 cap OD

It is used in the prevention and treatment of NSAIDinduced ulcers.

Hypersensitivity to omeprazole

Headache Diarrhea Constipation Abdominal Pain Nausea Vomiting Flatulence

1. Give before meals. 2. Do not crush or chew tablets, swallow whole. 3. Evaluate for therapeutic response like relief of Gastrointestinal symptoms. 4. Question if

into the gastric lumen. Omeprazole increases the gastric pH and reduces gastric acid formation.

Gastrointestinal discomfort, nausea, and diarrhea occurs.