Name: Chetan J. Phadke Class: M.Pharm (Pharmaceutics). Seminar Date: 17th March 2012.

Seminar Time: 3:00- 3:30 pm. Under the Guidance of: Mrs. Harsha Kathpalia

NOVEL TECHNIQUES IN ORAL SUSPENSION

Abstract: Oral drug delivery known for decades is the most widely utilized route for administration among all routes that have been explored for systemic delivery of different dosage forms. Popularity may be ease of administration as well a traditional belief that by oral administration the drug is well absorbed like food stuff ingested daily. Suspensions occupy a central role in drug development. Because Drug in suspension exhibits higher rate of bioavailability than other solid dosage forms. Conventional oral suspension have disadvantages like- Physical stability, sedimentation and compaction can causes problems, it is bulky sufficient care must be taken during handling and transport, it is difficult to formulate, uniform and accurate dose can not be achieved unless suspension are packed in unit dosage form. So novel techniques have tried to modify oral suspension, namely Nanosuspension, Taste masking and modified release oral suspension. These techniques have been used to improve stability and bioavailability of poorly soluble, obnoxious tasting drugs and potent drugs.