-

-
:
:

ziyadwetti@yahoo.com:

ziyadwetti@yahoo.com
THE ROLE OF CHOLESTEROL
Despite its negative portrayal by the popular press cholesterol is an essential
part of human metabolism. certainly, the role of cholesterol in health has been
clouded by the publics confusion over serum versus dietary cholesterol and
any relationship the two have to each other. the following article on the role of
cholesterol and fat in diet and heart disease was prepared by Dr.Ziyad wetti.
Department of Nutrition and Food Science ,GCSAR

.


.


.

%18
.

 :
()Cholesterols Chole
Stereos
OL
1824



1769 .
1815
. 1824




1856





1908

.
1910



:

% 75 . .

. D %25

.
.


:

.

.
:

 : HDL -1
: LDL -2
: VLDL-3

:
-1 : HDL
% 20 HDL

HDL
. HDL



.
-2 : LDL
LDL

()

.

LDL 159 %

.
-3 :


.



. 120-100
/ ( ) 2
:
( )LDL , HDL


( )LDL
( . )HDL
:
A
3 A ( )
A (HMG-
) CoA Reductase
( ) .

 30 -
.
3
.
:
:



.



:
:
-1 HDL
LDL .
-2 .


-3 HMG-CoA

.LDL
-4
.
-5

:
12

700 1000 1000
. %16
%10


:
(
)
. ( )1

( )1

80
6
70

100
28
82

150
19
2

205
22
26

230
24
36

220
19
27

150
5
55

30
2
42

245
18
24

290
16
19

360
14
57

( )


.
.


.
:
()


.
( )
:


.

%15-10 .

.

% 0.01


3-2

( )2

/
> 225
179-162
39-20
-1
>257
209-186
59-40
>262
213-189
60
-119
> 59-40 159
117-100
LDL
-2 20-39

>183
140
>190
143-122
60
>52
59-40 0.0
>51
HDL
-3 20-39
0.0
0.0
>60
60
> 59-40 195
93-71
39-20
-4
>231
121-89
>206
110-83
60
> 59-40 6.1
3.6-2.3
HDL
-5 20-39/
>7.4
4.2-2.6
>6.9
4.0-2.5
60

( )3 /

>220
176-157
39-20
-1
>259
209-186
59-40
>276
227-205
60
-110
> 59-40 149
108-90
LDL
-2 20-39
>181
128
>198
149-126
60
>69
59-40>63
HDL
-3 20-39
>74
60
> 59-40 146
77-58
39-20
-4
>190
98-73
>206
110-82
60
> 59-40 4.2
2.8-1.9
HDL
-5 20-39/
>4.9
3-2
>5.5
3.2-2
60
:




% 65

:

HDL
.




. :
- HDL .

 :

HDL
5 100/ 6.5100/

.

-
:

-
:
:

ziyadwetti@yahoo.com:

ziyadwetti@yahoo.com
THE ROLE OF CHOLESTEROL
Despite its negative portrayal by the popular press cholesterol is an essential
part of human metabolism. certainly, the role of cholesterol in health has been
clouded by the publics confusion over serum versus dietary cholesterol and
any relationship the two have to each other. the following article on the role of
cholesterol and fat in diet and heart disease was prepared by Dr.Ziyad wetti.
Department of Nutrition and Food Science ,GCSAR

:


.



.


.

%18
.
:
()Cholesterols Chole
Stereos
OL
1824



1769 .
1815
. 1824




1856





1908

.
1910



:

% 75 . .

. D %25

.

 .


:

.

.
:
: HDL -1
: LDL -2
: VLDL-3

:
-1 : HDL
% 20 HDL

HDL
. HDL



.
-2 : LDL
LDL

()

.

LDL 159 %

.
-3 :


.



. 120-100
/ ( ) 2
:
( )LDL , HDL


( )LDL
( . )HDL
:
A
3 A ( )
A (HMG-
) CoA Reductase
( ) .
30 -
.
3
.
:
:



.



:
:
-1 HDL
LDL .
-2 .


-3 HMG-CoA

.LDL
-4
.
-5

:
12

700 1000 1000
. %16
%10

 :
(
)
. ( )1

( )1

80
6
70

100
28
82

150
19
2

205
22
26

230
24
36

220
19
27

150
5
55

30
2
42

245
18
24

290
16
19

360
14
57

( )


.
.


.
:
()


.
( )
:


.

%15-10 .

.

% 0.01


3-2

( )2

/
> 225
179-162
39-20
-1
>257
209-186
59-40
>262
213-189
60
-119
> 59-40 159
117-100
LDL
-2 20-39
>183
140
>190
143-122
60
>52
59-40 0.0
>51
HDL
-3 20-39
0.0
0.0
>60
60
> 59-40 195
93-71
39-20
-4
>231
121-89
>206
110-83
60
> 59-40 6.1
3.6-2.3
HDL
-5 20-39/
>7.4
4.2-2.6
>6.9
4.0-2.5
60

( )3 /

>220
176-157
39-20
-1
>259
209-186
59-40
>276
227-205
60
-110
> 59-40 149
108-90
LDL
-2 20-39
>181
128
>198
149-126
60
>69
59-40>63
HDL
-3 20-39
>74
60
> 59-40 146
77-58
39-20
-4
>190
98-73
>206
110-82
60
> 59-40 4.2
2.8-1.9
HDL
-5 20-39/
>4.9
3-2
>5.5
3.2-2
60
:




% 65

:


HDL
.




. :
HDL . :

HDL
5 100/ 6.5100/

.