Mathematics and Physics of Emerging Biomedical Imaging (1996)
Mathematics and Physics of
Emerging Biomedical
Imaging
Committee on the Mathematics and Physics of
Emerging Dynamic Biomedical Imaging
Board on Mathematical Sciences
Board on Physics and Astronomy
Commission on Physical Sciences, Mathematics,
and Applications
National Research Council
and
Board on Biobehavioral Sciences and Mental Disorders
Institute of Medicine
National Academy Press
Washington, D.C. 1996Mathomatics and Physics of Emerging Biomedical Imaging (1006)
NOTICE: The project that is the subject of this report was approved by
the Governing Board of the National Research Council, whose members are
drawn from the councils of the National Academy of Sciences, the National
‘Academy of Engineering, and the Institute of Medicine. The members of
the committee responsible for the report were chosen for their special com
petences and with regard for appropriate balance.
‘This report has been reviewed by a group other than the authors ac-
cording to procedures approved by a Report Review Committee consisting
of members of the National Academy of Sciences, the National Academy of
Engineering, and the Institute of Medicine.
Support for this project was provided by the Advanced Research Projects
Agency, the Department of Energy, and the National Institute of Mental
Health.
Library of Congress Catalog Card Number 95-72622
International Standard Book Number 0-309-05387-0
Copyright 1996 by the National Academy of Sciences. All rights reserved.
Available from
National Academy Press
2101 Constitution Avenue, NW
Washington, DC 20418
Available on the Internet via the World Wide Web at the URL:
http://www.nas.edn/
Printed in the United States of America
COVER ILLUSTRATIONS: The upper figure was produced by rapid volu-
metric magnetic resonance imaging (MRI) after injection of a paramagnetic
contrast agent and shows vessel anatomy, kidney perfusion, and ureters
(bright). The contrast agent causes urine and blood to produce different
magnetic resonance signals. (Ilustration courtesy of George Holland, Uni-
versity of Pennsylvania and General Electric Medical Systems.) The lower il-
lustration, an example of modern non-invasive computed tomography (CT),
shows calcium deposits in the aorta (center of image) and the blood vessel
anatomy. It was produced using rapid data collection via spiral CT with
injected contrast material. (ustration courtesy of Siemens Medical Sy
tems.)Matomates and Physicg of Emaruing Bomedica Imaging (1006)
COMMITTEE ON THE MATHEMATICS AND PHYSICS OF
EMERGING DYNAMIC BIOMEDICAL IMAGING
‘Tuomas BubinGer, Lawrence Berkeley National Laboratory, Co-chair
Feuix Wexrui, University of Pennsylvania Medical Center, Co-chair
S. Morais Brumenretp, General Electric Medical Systems
F. ALBERTO Grinnavat, University of California at Berkeley
R. MARK HenkeLMan, University of Toronto
Paut C. LAUTERBUR, University of Ilinois at Urbana-Champaign
Witrniep LOprFter, Siemens Medical Systems, Inc.
FRANK NATTERER, University of Muenster
Saran Jae Neison, University of California at San Francisco
Lawrence Suer?, AT&T Bell Laboratories
Roserr G. SHULMAN, Yale University
BENJAMIN MING Wax Tsvt, University of North Carolina at Chapel Hill
Scorr T. Wewsan, Senior Staff Officer, Board on Mathematical Sciences
Rosear L. Riswpr, Associate Director, Board on Physics and Astronomy
Constaxcr M. Pacuvaa, Director, Board on Biobehavioral Sciences
and Mental Disorders
iti