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Contents
Classification History Introduction Indications Key terms- compliance , ventilatory work Components Control mechanism Variables Triggering Factors to consider in mechanical ventilation
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Classification
According to Robert chatburn Broadly classified into
ventilators
Positive pressure
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Exert a negative pressure on the external chest during inspiration allows air to flow into the lung, filling its volume ventilation is similar to spontaneous ventilation
failure associated with neuromascular conditions such as poliomyleitis, muscular dystrophy, a myotrophic lateral sclerosis, and 5/30/12 mysthenia gravis.
referred to in the early days as the "Drinker respirator", was invented byPhillip Drinker(1894 1972) andLouis Agassiz Shaw Junior,professors ofindustrial hygiene at theHarvard School of Public Health .
The machine was
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method ofventilation which requires the patient to wear an upper body shell orcuirass, so named after the body armour worn by medieval soldiers. cuirass is attached to a pump which actively controls both theinspiratory andexpiratory phases of the respiratory cycle .
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Disadvantages
Complex and Cumbersome Difficult for transporting Difficult to access the patient in emergency claustrophobic
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pressure on the airway, similar to a bellows mechanism, forcing the alveoli to expand during inspiration
Expiration occurs passively. modern ventilators are mainly PPV s and
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History
Andreas Vesalius (1555) Vesalius is credited with the first description
of positive-pressure ventilation, but it took 400 years to apply his concept to patient care. The occasion was the polio epidemic of 1955, when the demand for assisted ventilation outgrew the supply of negative-pressure tank ventilators (known as iron lungs).
In Sweden, all medical schools shut down and
medical students worked in 8-hour shifts as human ventilators, manually inflating the lungs of afflicted patients.
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patients who are unable to sustain the level of ventilation necessary to maintain the gas exchange functions-oxygenation and carbon dioxide elimination
The first positive-pressure ventilators were
Key terms
Ventilatory workDuring inspiration , the size of the thoracic cage
increases overcoming the elastic forces of the lungs and the thorax and resistance of the airways. As the volume of the thoracic cage increases, intrapleural pressure becomes more negative, resulting in lung expansion.
Gas flows from the atmosphere into the lungs as a result
thorax cause the chest to decrease in volume and exhalation occurs as a result of greater pressure at the alveolus compared to atm. Press.
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referred to as the load that the muscles or ventilator must work against. elastic ( volume & inv. Prop t0 compliance)
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load
Lung compliance
Lung compliance: Is the change in volume per
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Types
Static compliance- is measured when there
is no air flow.
flow is present
Plateau pressure-
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INPUT POWER
It can be Pneumatically powered(uses compressed
gases)
AC/12Volts DC) Here the electric motor drives pistons and compressors to generate gas flows .
Microprocessor controlled- combined.
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DRIVE MECHANISM
Its the system used by the ventilator to
transmit or convert the input power to useful ventilatory work. pressure patterns produced by the ventilator. pistons bellows reducing valves
It includes
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pneumatic circuits
Piston mechanism
Bellows mechanism Pneumatic mechanism
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power source.
these are microprocessor controlled with
solenoid valves.
use programmed algorithms in
microprocessor to open and close solenoid valves to mimic any flow or pressure wave pattern.
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Control circuit
Its the system that governs the ventilator
and venti. Measures a specific parameter (flow/vol/press) continuously and input is constantly adjusted to match desired output.
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Control parameters
Pressure Volume Flow Time
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positive pressure at a certain rate. The amount of gas delivered can be limited by time, pressure or volume. The duration can be cycled by time, pressure or flow. If volume is set, pressure varies..if pressure is set, volume varies.. .according to the compliance...
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control direction of other gas flows and to perform logic functions based on the COANDA effect.
Electronic- uses resistors and diodes and
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Pressure controller
Ventilator controls the trans-respiratory
system pressure .
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Volume controller
Volume cycled ventilation delivers a: set volume; with a variable Pressure - determined by
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Flow controller
Allows pressure to vary with changes in
Time controller
measures and controls inspiratory and expiratory time.
Normal inspiratory time of a spontaneously breathing healthy adult is approximately 0. 8- 1.2 seconds, with an inspiratory expiratory (I: E) ratio of 1:1.5 to 1:2 2. Its advantageous to extend the inspiratory time in order to: improve oxygenation - through the addition of an inspiratory pause; or to increase tidal volume - in pressure controlled ventilation Adverse effects of excessively long inspiratory times are haemodynamic compromise, patient ventilator dysynchrony, and the development of autoPEEP.
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Phase variables
A. Trigger .
What causes the breath to begin?
B A
B. Limit
What regulates gas flow during the breath?
C. Cycle .
What causes the breath to end?
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inspiration change from inspiration to expiration expiration change from expiration to inspiration Types of ventilator breathsMandatory breath
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Trigger variable
Its the variable that determines start of
inspiration
which the ventilator senses inspiratory effort and delivers gas flow or a machine breath in concert with the patients inspiratory effort.
Can use pressure or volume or time or flow as
a trigger.
triggered by either a fall in pressure (pressure 5/30/12 triggered) or a change in flow (flow triggered).
Time triggering
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Pressure Triggering
spontaneous inspiratory effort.
Breath is delivered when ventilator senses patients sensitivity refers to the amount of negative pressure the
generate 1 cm H2O of negative pressure for the machine to sense the patient's effort and deliver a breath.
Acceptable range - -1 to -5 cm H2O below patient s
baseline pressure
If the sensitivity is too high the patient's work of breathing
will be unnecessarily increased. It is not a reasonable course of action to increase the sensitivity to reduce the 5/30/12 patient's respiratory rate as it only increases their work of
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Flow Triggering
flows continuously through the circuit. The patients earliest demand for flow is satisfied by the base flow.
The flow sensitivity is computed as the
difference between the base flow and the exhaled flow flow
Here delivered flow= base flow- returned Hence the flow sensitivity is the magnitude of
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Flow trigger Advantages -The time taken for the onset of inspiratory effort to the onset of inspiratory flow is considerably less. -decreases the work involved in initiating a breath.
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Limit variable
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Cycle variable
Defined as the length of one complete
Inspiration ends when a specific cycle variable This variable is used as a feedback signal to
end inspiratory flow delivery which then allows exhalation to start. as a feedback signal. time
Most new ventilators measure flow and use it So volume becomes a function of flow and 5/30/12
Baseline variable
The variable controlled during expiration
phase.
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Basic definitions
Airway Pressures
Peak Inspiratory Pressure (PIP) Plateau pressures Positive End Expiratory Pressure (PEEP) Continuous Positive Airway Pressure (CPAP)
Inspiratory Time or I:E ratio Tidal Volume: amount of gas delivered with each
breath
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Pressures
Mechanical ventilation delivers flow and
volume to the patients as a result of the development of a positive pressure gradient between the ventilator circuit and the patients gas exchange units as illustrated in the diagram above. There are four pressures to be aware of in regards to mechanical ventilation. These are the:
Peak Plateau
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The peak pressure is the maximum pressure obtainable during active gas delivery. This pressure a function of the compliance of the lung and thorax and the airway resistance including the contribution made by the tracheal tube and the ventilator circuit.
Plateau Pressure-
The plateau pressure is defined as the end 5/30/12 inspiratory pressure during a period of no gas
there is no flow within the circuit and patient airways it most closely represents the alveolar pressure and thus is of considerable significance as it desirable to limit the pressure that the alveoli are subjected to. extrapulmonary air (eg pneumothorax) and acute lung injury. ETT resistance) will result in an increase in PIP.
occlusion pressure (ie plateau pressure) is the best clinically applicable estimate of average peak alveolar pressure. Although controversial it has been generally recommended that the plateau pressure should be limited to 35 cms H2O.
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The mean airway pressure is an average of the system pressure over the entire ventilatory period.
End expiratory pressure is the airway pressure at the termination of the expiratory phase and is normally equal to atmospheric or the applied PEEP level. 5/30/12
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PEEP
to the application of a fixed amount of positive pressure applied during mechanical ventilation cycle refers to the addition of a fixed amount of positive airway pressure to spontaneous respirations, in the presence or absence of an endotracheal tube.
ventilation as they do not provide ventilation. Rather they are used together with other modes of ventilation or during spontaneous 5/30/12
Advantages
ability to increase functional residual capacity
increasing alveolar volume and through the recruitment of alveoli that would not otherwise contribute to gas exchange. Thus increasing oxygenation and lung compliance
The potential ability of PEEP and CPAP to open
closed lung units increases lung compliance and tends to make regional impedances to ventilation more homogenous. 5/30/12
positive pressure gradient. In spontaneous respiration gas flow occurs due to the generation of a negative pressure in the alveoli relative to atmospheric or circuit pressure (as in CPAP) (refer to following diagram).
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Physiology of PEEP
Reinflates collapsed alveoli and maintains
PEEP Decreases alveolar distending pressure Increases FRC by alveolar recruitment Improves ventilation
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Dangers of PEEP
High intrathoracic pressures can cause
pulmonary disease
metabolism
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AutoPEEP
During expiration alveolar pressure is greater
than circuit pressure until expiratory flow ceases. If expiratory flow does not cease prior to the initiation of the next breath gas trapping may occur. Gas trapping increases the pressure in the alveoli at the end of expiration and has been termed:
patient to:
an increased risk of barotrauma; fall in cardiac output; hypotension; fluid retention; and an increased work of breathing
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I:E ratio
This defines the inspiration to expiration ratio. I:E ratios are normally set as 1:2 as expiration requires a longer
time .
be set as 1:4
Factors affecting I:E Ratio1. Tidal volume 2. Respiratory rate 3. Flow rate
Increasing inspiration time will increase TV, but may lead to
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auto-PEEP
Tidal Volume
Tidal volume refers to the size of the breath that is
ml / kg whereas the traditional aim for tidal volumes has been approximately 10 - 15 ml / kg.
The rationale for increasing the size of the tidal volume in
ventilated patients has been to prevent atelectasis and overcome the deadspace of the ventilator circuitry and endotracheal tube.
Inspired and expired tidal volumes are plotted on the y
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generally correlate.
Expired tidal volumes may be less than
causing some of the gas delivered to the patient to leak into the atmosphere
there is a leak around the endotracheal /
bronchopleural fistula
volume of gas is delivered, or exhaled, per unit of time. Flow is described in litres per minute . the maximum flow delivered to a patient per ventilator breath.
is plotted above the zero flow line, whereas expiratory flow is plotted as a negative deflection. When the graph depicting flow is at 5/30/12
Flow
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primary factors to consider when applying mechanical ventilation of each individual breath, the components
the method of triggering the mechanical
specifically whether pressure, flow, volume and time are set by the operator, variable or dependent on other parameters ventilator breath/gas flow,
ventilation.
synchrony; and
Time (Ti)
Time in mechanical ventilation is divided between
flow rate, flow waveform and inspiratory pause. Where inspiratory time is able to be set, flow becomes dependent 5/30/12 on inspiratory time and tidal volume.
because gas is constantly being delivered at a flow rate of 60 lpm, which equals 1 litre per second. If an inspiratory pause of 0.5 seconds were applied then the inspiratory time would be increased to 1.5 seconds.
Changing the patients flow waveform from a square to a
decelerating 5/30/12
Output waveforms
Graphical representation of the control or
presented as
variable whereas the other two depend on the patient compliance and resistance.
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Advantages
Allows user to interpret, evaluate, and troubleshoot
the ventilator and the patients response to ventilator. Monitors the patients disease status (C and Raw). Assesses patients response to therapy.
Monitors ventilator function Allows fine tuning of ventilator to decrease WOB,
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Flow Waveforms
of flow delivered to the patient during inspiration, whereas the flow waveform determines the how quickly gas will be delivered to the patient throughout various stages of the inspiratory cycle.
There are four different types of flow
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Square waveform The square flow waveform delivers a set flow rate
throughout ventilator inspiration. If for example the peak flow rate is set at 60 lpm then the patient will receive 60 lpm throughout ventilator inspiration.
Decelerating waveform The decelerating flow waveform delivers the peak flow at
the start of ventilator inspiration and slowly decreases until a percentage of the peak inspiratory flow rate is attained.
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delivers a fraction of the peak inspiratory flow and steadily increasing the rate of flow until the peak flow has been reached.
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Setting the Peak Flow and Flow Waveform the The flow rate should be set to match
patients inspiratory demand. Where the patients inspiratory flow requirements exceed the preset flow rate there will be an imposed work of breathing which may cause the patient to fight the ventilator and become fatigued.
Where flow rate is unable to match the
patients inspiratory flow requirements the pressure waveform on the ventilator graphics screen may show a depressed or scooped out pressure waveform.
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frequently selected flow waveform as it produces the lowest peak inspiratory pressures of all the flow waveforms.
alveolar expansion. Initially a high flow rate is required to open the alveoli. Once alveolar opening has occurred a lower flow rate is sufficient to procure alveolar expansion.
Flow waveforms which produce a high flow
rate at the end of inspiration (ie. square and accelerating flow waveforms) exceed the flow 5/30/12 requirements for alveolar expansion, resulting
Pressure waveforms
Rectangular Exponential rise Sine
Can be used to monitor Air trapping (auto-PEEP) Airway Obstruction Bronchodilator Response Respiratory Mechanics (C/Raw) Active Exhalation Breath Type (Pressure vs. Volume) PIP, Pplat CPAP, PEEP Asynchrony
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References
Guide to mechanical ventilation- chang s Breathing and mechanical support- wolfgang
oczenski
Internet references
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Thank you
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ventilation is the ability to set a tidal volume. This is of critical importance to patients requiring tight regulation of carbon dioxide elimination. Neurosurgical patients - post surgery / head injury and patients suffering a neurological insult (eg post cardiac arrest) often require CO2 regulation. This is because carbon dioxide is a potent vasodilator.
therefore increase cerebral blood volume with a concomitant elevation of intracranial pressure. A raised intracranial pressure may decrease the delivery of oxygenated blood to the brain - resulting in cerebral ischaemia. Conversely a low CO2 may cause constriction of the cerebral vasculature also resulting in decreased oxygen delivery and cerebral ischaemia. For these reasons volume cycled ventilation is 5/30/12the mode of choice for patients requiring CO2 regulation. often
Disadvantages
The major disadvantages of volume cycled
ventilation are the variable pressure and set flow rate. It is therefore a necessary part of nursing practice to closely monitor the patient's inspiratory pressure and observe the patient for signs of flow starvation.
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