Generic/ Trade name Dosage and frequency Generic name: -Losartan

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Antihypertensive Selectively blocks the binding of Trade name: angiotensin II to -Cozaar specific tissue receptors found Dosage in the vascular -50 mg 1 tab OD smooth muscle and adrenal gland; this action blocks the vasoconstriction effect of the renninangiotensin system as well as the release of aldosterone leading to decreased BP.

-Decrease BP -Increase potassium -GI upset -facial/ angioedema -dizziness -cough -weakness -decrease renal function

Indication: -hypertensive -prevent CVA in HTN and LVH Contraindication: -patients who are hypersensitive to any component of the drug.

*Patient blood pressure is 200/110 160/90 Check: -Monitor patient closely in any situation that may lead to a decrease BP secondary to reduction in fluid volume excessive perspiration, dehydration, vomiting, and diarrhea excessive hypotension can occur

Generic/ Trade name Dosage and frequency Generic name: -Clonidine Trade name: -Catapres Dosage: -PRN

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Antihypertensive Centrally acting -centrally acting antiadrenergic sympatholytic derivative. Stimulates alpha2adrenergic receptors in CNS to inhibit sympathetic vasomotor centers. Central actions reduce plasma concentrations of norepinephrine. It decreases systolic and diastolic BP and heart rate. Orthostatic effects tend to be mild and occur infrequently. Also inhibits

-Orthostatic decrease BP -bradycardia -Drowsiness -dizziness -light headedness -headache -weakness -dry mouth -GI upset -nightmares -impotence

Indication: - Essential renal and malignant hypertension Contraindication: -patient hypersensitive to clonidine

-Urinary retention -changes in vision -blanching of fingers -rash

Check: -History of hypersensitivity to clonidine -severe coronary insufficiency -recent MI -cerebrovascular disease -Monitor blood pressure and pulse rate -May be given rapidly lower blood pressure in some hypertensive emergencies -Rising slowly and avoid sudden position change to prevent orthostatic hypotension.

renin release from kidneys..

-Remove patch before defibrillation to prevent arcing *Patient has a hypertension stage two thus this drug is given to decrease his blood pressure.

Generic/ Trade name Dosage and frequency Generic name: Citicholine Trade name: -Somazine Dosage: -1g TID

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Neurotonics

Citicoline is aninter neuronal communication enhancer. It increases the neurotransmission levels because it favors the synthesis and production speed of dopamine in the striatum, acting then as a dopaminergic agonist thru the inhibition of tyrosinehydroxylase

-Low blood pressure (faintness, dizziness) -Slow or fast heart beat -Headache -Nausea and Vomiting or diarrhea

Indication; CVD in acute & recovery phase, symptoms &signs of cerebral in sufficiency (dizziness, memory loss, poor concentration, disorientation, recent cranial trauma & their squeal.) Contraindication; Parasympathetic hypertonia

-Itching or hives -swelling in face or hands -tingling in your mouth or throat -chest tightness -trouble breathing -rash

Check: -hypersensitivity to citicholine - Somazine must not be administered along with medicaments containing meclophenoxate. *The patient has been stroke (patient who experience stroke usually has/had a speech problem) the patient had a speech difficulty, and is now diminished because of these drug.

Generic/ Trade name Dosage and frequency Generic name: -Clopidogrel Trade name: -Plavix Dosage: -75 mg tab OD

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Anti-platelet

Inhibits platelet aggregation by blocking ADP receptors on platelets, preventing clumping of platelets.

-Dizziness -light headedness -headache -nausea -gastric distress -prolong bleeding

Indication: Treatment of patient at risk for ischemia events such as recent MI, recent ischemia CVA Contraindication: -Contra indicated with allergy to clopidogrel, -active pathological bleeding such as peptic ulcer or intracranial hemorrhage, lactation.

-Skin rash -chest pain -fainting -severe headache -abnormal bleeding

Check for; -Allergy to clopidogel -recent surgery -hepatic impairment Physical: -skin color -temperature -lesions -BP -baseline ECG -adventitious sounds -Assess for symptoms of stroke, MI during treatment -Monitor liver function: creatinine if patient is on long-term therapy -Monitor blood

studies: CBC, Hgb, Hct, protime, cholesterol if the patient is on long-term therapy; thrombocytopenia and neutropenia may occur. *The patient experience stroke thus this drug is given to prevent MI

Generic/ Trade name Dosage and frequency Generic name: -Omeprazole Trade name: -Losec Dosage: -40 mg 1 tab OD

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Antisecretory drug Proton pump inhibitor

Gastric acidpump inhibitor: Suppresses gastric acid secretion by specific inhibition of the hydrogenpotassium ATPase enzyme system at the secretory surface of the gastric parietal cells; blocks the final step of acid production.

-Headache -dizziness -asthenia -vertigo -insomnia -apathy -anxiety -paresthesias -dream abnormalities -urticaria -pruritus -alopecia -diarrhea -abdominal pain -nausea -vomiting -constipation -dry mouth -tongue atrophy -URI symptoms -cough -epistaxis

Indication: -Short-term treatment of active duodenal ulcer; First-line therapy in treatment of heartburn or symptoms of gastro esophageal reflux disease (GERD) -Short-term treatment of active benign gastric ulcer; -GERD, severe erosive esophagitis, poorly responsive symptomatic GERD; -Long-term therapy: Treatment of pathologic hypersecretory conditions

Check: -History: hypersensitivity to omeprazole or any of its components; pregnancy, lactation -Physical: skin lesions, reflexes, urinary output; abdominal examination; respiratory auscultation -Administer before meals -Administer antacids with, if needed -.Have regular medical follow-upvisits -Report severe headache, worsening of symptoms, fever, chills.

(Zollinger-Ellison syndrome, multiple adenomas, systemic mastocytosis); -Eradication of H. pylori with amoxicillin or metronidazole and clarithromycin

Contraindication: -Contraindicated with hypersensitivity to omeprazole or its components; Use cautiously with pregnancy, lactation.