Safety data sheet

N-Vinyl-2-pyrrolidone non-stab.
Revision date : 2008/12/17 Version: 2.0 Page: 1/8 (30036596/MDS_GEN_US/EN)

1. Substance/preparation and company identification

Company BASF CORPORATION 100 Campus Drive Florham Park, NJ 07932, USA 24 Hour Emergency Response Information CHEMTREC: 1-800-424-9300 BASF HOTLINE: 1-800-832-HELP

Molecular formula: Chemical family: Synonyms:

C(6)H(9)NO unspecified, amine 1-ETHENYL-2-PYRROLIDINONE

2. Composition/information on ingredients
CAS Number 88-12-0 616-45-5 Content (W/W) > 99.0 % <= 0.2 % Chemical name 1-vinyl-2-pyrrolidone 2-Pyrrolidone

3. Hazard identification
Emergency overview WARNING: Causes eye irritation. MAY CAUSE SKIN IRRITATION. MAY BE HARMFUL IF SWALLOWED. HARMFUL IF INHALED. Use with local exhaust ventilation. Wear a NIOSH-certified (or equivalent) organic vapour/particulate respirator. Wear NIOSH-certified chemical goggles. Wear protective clothing. Eye wash fountains and safety showers must be easily accessible. Wear full face shield if splashing hazard exists. Potential health effects Primary routes of exposure Routes of entry for solids and liquids include eye and skin contact, ingestion and inhalation. Routes of entry for gases include inhalation and eye contact. Skin contact may be a route of entry for liquified gases. Acute toxicity: Of moderate toxicity after short-term inhalation. Of moderate toxicity after short-term skin contact. Of moderate toxicity after single ingestion. Irritation: May be irritating to the airways. May cause severe damage to the eyes. Sensitization:

Safety data sheet

N-Vinyl-2-pyrrolidone non-stab.
Revision date : 2008/12/17 Version: 2.0
Skin sensitizing effects were not observed in animal studies. Repeated dose toxicity: The substance may cause a specific damage to organs through repeated inhalative exposure. Information on: N-Vinyl Pyrrolidone Rats exhibited minor liver changes at airborne levels of 15 ppm and irritation of the nasal mucosa at 5 ppm. The results of a two year inhalation study indicate that rats exposed to 5, 10 and 20 ppm NVP exhibited benign or malignant tumors of the nasal tissues. Only benign tumors were observed among females at 10 ppm and males and females at5 ppm. Liver damage was noted at all dose levels, including a significant increase in the occurrence of malignant tumors in the livers of the high dose animals. Tumors of the larynx were also observed among the animals at the highest dose. Information on: N-Vinyl Pyrrolidone (NVP) N-vinylpyrrolidone is moderately toxic by ingestion and may be absorbed via skin or inhalation. Acute and subchronic animal studies indicate that overexposure to NVP by ingestion or inhalation may result in liver and kidney injury. Information on: N-Vinyl Pyrrolidone (NVP) In a screening study, liver tumors were reported in male mice administered a single intraperitoneal injection of NVP and allowed to mature to the age of 10 months. Medical conditions aggravated by overexposure: Data available do not indicate that there are medical conditions that are generally recognized as being aggravated by exposure to this substance/product. See MSDS section 11 - Toxicological information. Potential environmental effects Aquatic toxicity: Acutely harmful for aquatic organisms. The inhibition of the degradation activity of activated sludge is not anticipated when introduced to biological treatment plants in appropriate low concentrations.

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4. First-aid measures
General advice: Remove contaminated clothing. If inhaled: Remove the affected individual into fresh air and keep the person calm. Assist in breathing if necessary. Immediate medical attention required. If on skin: Wash affected areas thoroughly with soap and water. Remove contaminated clothing. Wash soiled clothing immediately. If irritation develops, seek medical attention. If in eyes: In case of contact with the eyes, rinse immediately for at least 15 minutes with plenty of water. If irritation develops, seek medical attention. Immediate medical attention required. If swallowed: Rinse mouth and then drink plenty of water. Induce vomiting. Never induce vomiting or give anything by mouth if the victim is unconscious or having convulsions. Immediate medical attention required.

5. Fire-fighting measures
Flash point: Autoignition: Lower explosion limit: Upper explosion limit: Flammability: 95 C 240 C 1.4 %(V) 10.0 %(V) not readily ignited (DIN 51758) (DIN 51794)

Safety data sheet

N-Vinyl-2-pyrrolidone non-stab.
Revision date : 2008/12/17 Version: 2.0
Suitable extinguishing media: water fog, foam, dry extinguishing media Hazards during fire-fighting: nitrogen oxides See MSDS section 10 - Stability and reactivity. Protective equipment for fire-fighting: Firefighters should be equipped with self-contained breathing apparatus and turn-out gear. Further information: Collect contaminated extinguishing water separately, do not allow to reach sewage or effluent systems. NFPA Hazard codes: Health : 2 Fire: 1

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Reactivity: 0

Special:

6. Accidental release measures

Personal precautions: Wear appropriate respiratory protection. Use personal protective clothing. Ensure adequate ventilation. Environmental precautions: Do not empty into drains. Do not discharge into drains/surface waters/groundwater. This product is not regulated by RCRA. Cleanup: For large amounts: Pump off product. For residues: Pick up with suitable absorbent material (e.g. sand, sawdust, general-purpose binder, kieselguhr). Dispose of absorbed material in accordance with regulations.

7. Handling and storage

Handling General advice: Ensure thorough ventilation of stores and work areas. Protect against heat. Product solidified and/or tending to sedimentation in barrels can be liquified or homogenized by careful application of indirect heat (no naked flames or direct contact with a heat source). Homogenize before use. See MSDS section 10 - Stability and reactivity. See MSDS section 5 - Fire fighting measures. Protection against fire and explosion: Prevent electrostatic charge - sources of ignition should be kept well clear - fire extinguishers should be kept handy. Heated containers should be cooled to prevent polymerization. Storage General advice: Keep only in the original container. Storage incompatibility: General: Segregate from acids and acid forming substances. Storage stability: Storage temperature: 17 - 23 C Storage duration: 14 d May yellow after lengthy storage.

Safety data sheet

N-Vinyl-2-pyrrolidone non-stab.
Revision date : 2008/12/17 Version: 2.0 Page: 4/8 (30036596/MDS_GEN_US/EN)
Temperature tolerance Protect from temperatures above: 25 C Changes in the properties of the product may occur if substance/product is stored above indicated temperature for extended periods of time.

8. Exposure controls and personal protection

Components with workplace control parameters 1-vinyl-2-pyrrolidone ACGIH TWA value 0.05 ppm ; Advice on system design: Provide local exhaust ventilation to control vapours/mists. Personal protective equipment Respiratory protection: Wear a NIOSH-certified (or equivalent) organic vapour/particulate respirator. Do not exceed the maximum use concentration for the respirator facepiece/cartridge combination. For emergency or non-routine, high exposure situations, use a NIOSH-certified full facepiece pressure demand self-contained breathing apparatus (SCBA) or a full facepiece pressure demand supplied-air respirator (SAR) with escape provisions. Hand protection: Chemical resistant protective gloves Eye protection: Tightly fitting safety goggles (chemical goggles). Wear face shield if splashing hazard exists. General safety and hygiene measures: Wear protective clothing as necessary to prevent contact. Handle in accordance with good industrial hygiene and safety practice.

9. Physical and chemical properties

Form: Odour: Colour: pH value: melting range: Boiling range: Vapour pressure: Density: Partitioning coefficient n-octanol/water (log Pow): Viscosity, dynamic: Solubility in water: Miscibility with water: Solubility (qualitative): liquid odourless, amine-like colourless to yellowish 9 - 10 13 - 14 C 90 - 92 C 0.12 mbar 1.23 mbar 1.043 g/cm3 0.4 2.4 mPa.s

( 100 g/l, 20 C) ( 13 mbar) ( 20 C) ( 50 C) ( 20 C) ( 25 C) ( 20 C) ( 20 C) miscible ( 20 C) miscible in all proportions

miscible solvent(s): organic solvents,

10. Stability and reactivity

Conditions to avoid: No conditions known that should be avoided. Substances to avoid: free radical initiators, acids, oxidizing agents, peroxides

Safety data sheet

N-Vinyl-2-pyrrolidone non-stab.
Revision date : 2008/12/17 Version: 2.0 Page: 5/8 (30036596/MDS_GEN_US/EN)

Hazardous reactions: Heat develops during polymerization. The product can polymerize if the shelf life or storage temperature are greatly exceeded. Reacts with oxidizing agents. Corrosion to metals: No corrosive effect on metal.

11. Toxicological information

Acute toxicity Oral: LD50/rat: 1,022 mg/kg (BASF-Test)

Inhalation: LC50/rat: 3.07 mg/l / 4 h(BASF-Test) rat: / 8 h(IRT) No mortality within the stated exposition time as shown in animal studies. Dermal: LD50/rabbit: > 400 mg/kg (BASF-Test) No mortality was observed. Skin irritation: rabbit: non-irritant (BASF-Test)

eye irritation : rabbit: Irritant. (Draize test) The European Union (EU) has classified this substance with 'Risk of serious damage to eyes' (R41) Sensitization: Buehler test/guinea pig: Non-sensitizing. (OECD Guideline 406)

Chronic toxicity Genetic toxicity: The substance was not mutagenic in bacteria. The substance was not mutagenic in mammalian cell culture. The substance was not mutagenic in a test with mammals. Carcinogenicity: Indication of possible carcinogenic effect in animal tests. Reproductive toxicity: The results of animal studies gave no indication of a fertility impairing effect. The results of animal studies suggest a fertility impairing effect.

12. Ecological information

Environmental fate and transport

Safety data sheet

N-Vinyl-2-pyrrolidone non-stab.
Revision date : 2008/12/17 Version: 2.0
Biodegradation: Test method: Method of analysis: Degree of elimination: Evaluation:

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OECD 301 A (new version) (aerobic), activated sludge, domestic DOC reduction 90 - 100 % (28 d) Readily biodegradable (according to OECD criteria).

Bioaccumulation: Because of the n-octanol/water distribution coefficient (log Pow) accumulation in organisms is not to be expected. Adsorbable organically-bound halogen (AOX): This product contains no organically-bound halogen.

Environmental toxicity Acute and prolonged toxicity to fish: OECD Guideline 203 static trout, rainbow/LC50 (96 h): 913 mg/l The details of the toxic effect relate to the nominal concentration. Acute toxicity to aquatic invertebrates: OECD Guideline 202, part 1 Daphnia magna/EC50 (48 h): 45 mg/l The details of the toxic effect relate to the nominal concentration. Toxicity to aquatic plants: DIN 38412 Part 9 green algae/EC50 (72 h): > 1,000 mg/l The details of the toxic effect relate to the nominal concentration. Toxicity to microorganisms: DIN 38412 Part 8 bacterium/EC50 (17 h): 4,812 mg/l The details of the toxic effect relate to the nominal concentration. OECD Guideline 209 aquatic activated sludge, industrial/EC20 (30 min): > 1,995 mg/l

13. Disposal considerations

Waste disposal of substance: Dispose of in accordance with national, state and local regulations. Incinerate or dispose of in a licensed facility. Container disposal: Packs must be completely emptied.

14. Transport information

Land transport USDOT Hazard class: Packing group: ID number: Hazard label: Proper shipping name: 6.1 III UN 2810 6.1 TOXIC LIQUID, ORGANIC, N.O.S. (contains 1-VINYL-2-PYRROLIDONE)

Safety data sheet

N-Vinyl-2-pyrrolidone non-stab.
Revision date : 2008/12/17 Version: 2.0
Sea transport IMDG Hazard class: Packing group: ID number: Hazard label: Marine pollutant: Proper shipping name: 6.1 III UN 2810 6.1 NO TOXIC LIQUID, ORGANIC, N.O.S. (contains 1-VINYL-2-PYRROLIDONE)

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Air transport IATA/ICAO Hazard class: Packing group: ID number: Hazard label: Proper shipping name: 6.1 III UN 2810 6.1 TOXIC LIQUID, ORGANIC, N.O.S. (contains 1-VINYL-2-PYRROLIDONE)

15. Regulatory information

Federal Regulations Registration status: TSCA, US

released / listed

OSHA hazard category: Skin and/or eye irritant, Other carcinogen, Chronic target organ effects reported, Acute target organ effects reported

SARA hazard categories (EPCRA 311/312): Chronic, Acute

State regulations State RTK CAS Number 616-45-5 Chemical name 2-Pyrrolidone State RTK MA, PA

16. Other information

HMIS III rating Health: 2

Flammability: 1

Physical hazard: 0

HMIS uses a numbering scale ranging from 0 to 4 to indicate the degree of hazard. A value of zero means that the substance possesses essentially no hazard; a rating of four indicates high hazard.

Local contact information prod_reg@basf.com

IMPORTANT: WHILE THE DESCRIPTIONS, DESIGNS, DATA AND INFORMATION CONTAINED HEREIN ARE PRESENTED IN GOOD FAITH AND BELIEVED TO BE ACCURATE , IT IS PROVIDED FOR YOUR GUIDANCE ONLY. BECAUSE MANY FACTORS MAY AFFECT PROCESSING OR APPLICATION/USE, WE RECOMMEND THAT YOU MAKE TESTS TO DETERMINE THE SUITABILITY OF A PRODUCT FOR YOUR PARTICULAR PURPOSE PRIOR TO USE. NO WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, ARE MADE REGARDING PRODUCTS DESCRIBED OR DESIGNS, DATA OR INFORMATION

Safety data sheet

N-Vinyl-2-pyrrolidone non-stab.
Revision date : 2008/12/17 Version: 2.0 Page: 8/8 (30036596/MDS_GEN_US/EN)
SET FORTH, OR THAT THE PRODUCTS, DESIGNS, DATA OR INFORMATION MAY BE USED WITHOUT INFRINGING THE INTELLECTUAL PROPERTY RIGHTS OF OTHERS. IN NO CASE SHALL THE DESCRIPTIONS, INFORMATION, DATA OR DESIGNS PROVIDED BE CONSIDERED A PART OF OUR TERMS AND CONDITIONS OF SALE. FURTHER, YOU EXPRESSLY UNDERSTAND AND AGREE THAT THE DESCRIPTIONS, DESIGNS, DATA, AND INFORMATION FURNISHED BY BASF HEREUNDER ARE GIVEN GRATIS AND BASF ASSUMES NO OBLIGATION OR LIABILITY FOR THE DESCRIPTION, DESIGNS, DATA AND INFORMATION GIVEN OR RESULTS OBTAINED, ALL SUCH BEING GIVEN AND ACCEPTED AT YOUR RISK. END OF DATA SHEET