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PCD P = C = D =

= Pussy Cat Disease (sorry Pussy Cat Dolls :) ) Pasteurella multocida Cellulitis enDotoxin

Clostridium Botulinum : Honey, I'm paralyzed because of that canned food. Please give me the anticholin bottle! Honey = spore ingested Paralyzed Eating canned food Please = Prophage Blocking the release of acetylcholine Bottle : botulinum Other classes of drugs with antimuscarinic pharmacology: Three crazy Parkinson patients are in pain, itching and having heart problems.. - Tricyclic antidepressant = Three - Antipsychotic = Crazy - Antiparkinson (amantadine ) - Meperidine = Pain - Antihistamine = Itching - Antidysrythmic (Quinidine) Interstitial pneumonia :CML for bacteria, CMV for virus CML : Chlamydia, Mycoplasma, Legionella Antineoplastic with less emetogenic potential : ViVi said, " Butter Bloated Me but Doxtor Helped Me ! " Vi- Vincristine Vi- Vinblastin Butter - Busulfan Bloated - Bleomycin Doxtor - Doxorubicin Helped - Hydroxyuria Me - Me = Methotrexate, Mercaptopurine Trinucleotide Repeat Expansion : Fredrich goes hunting then he is becoming fragi le because of muscle problem - Fredrich ataxia - Huntington disease - Fragile X syndrome - Myotonic dystrophy From mnemonic books pharma: Examples of the mnemonic or memory techniques or strategies used in this PharMne monics: 1> Linking a drug name (Pilocarpine) to its action (Pupil constriction): PILOCARPINE: A PILE of CAR-delivered PINEs is used for the pupil constri(u)ction project (illustruated with a figure). 2> Linking a drug class stem (-pril) to its action (Inhibition of an enzyme call ed ACE): PRIL: PERIL is gone with E (Enzyme ACE). By knocking out the E, the PERIL is rep laced with a -PRIL pill and the capital PERIL of hypertension and CHF can be dim inished by captoPRIL (illustruated with a figure). 3> Linking a drug name (Sumatriptan) to its use (treatment of Migraine):

SUMATRIPTAN: If you have migraine in the SUMMER, simply take A TRIP for TAN. Jus t relax (illustruated with a figure). 4> Linking a drug name (PHENyTOIN) to its side effects: Peripheral neuropathy. Hyperplasia of gingiva, Hirsutism and coarse facial features. Hypersensitivity: skin rash and even Stevens-Johnson syndrome. Enlarged lymph nodes (lymphadenopathy). Nystagmus, diplopia and sedation. Teratogenicity ("Fetal hydantoin syndrome"). Osteomalacia (due to decreased Vitamin D), megalOblastic anemia (due to deceased folate levels). Inhibition of ADH and insulin secretion. Nausea and vomiting 5> Linking a drug class (SSRIs) to its side effects: Sick stomach, leading to anorexia, nausea, etc. Sexual dysfunction. Restless: agitation, anxiety and tremor. Insomnia. Serotonin syndrome. Caused by concurrent use of MAOIs 6> Linking a disease name (DIABETES mellitus) to its drugs or drug classes: DDP-4 inhibitors (Sitagliptin) Insulins. Amylin analog (Pramlinitide). Acarbose (Alpha-glucosidase inhibitors). Biguanides (Metformin). Exenatide (GLP-1 agonists). Thiazolidinediones (PPARr agonists). Excercise and weight control (Essential for the control of type II DM). Sulfonylureas(Insulin secretagogues). 7> Dr. Bright's hint: Intern: Doc, of drugs used in Parkinson's disease, what drugs are better for rel ieving Bradykinesia? Dr: Bromocriptine and related DA agonists. Intern: Then, what drugs are better for attenuating Tremor? Dr: Trihexyphenidyl and related antimuscarinic agents. 8> Dr. Bright's hint: Intern: Doc, why can lithium cause nephrogenic diabetes insipidus? Dr: As you can see in the figure on the left, this is because the lithium batter y overcharges the water pump in the kidney. 9> Cartoons and humors: This feature may be sensed from the Front cover image: The man in the platelet on the left side stands for ASPIRIN (AS a PI [Platelet I nhibitor], I REIN COX-1 [the wheel] with an acetyl chain [CH3-CO-]); The dog on the top of the platelet on the right side represents CLOPIDOGREL (As a CLOPI [CLOt/Platelet Inhibitor], this DOG is for REaL in blocking the ADP rece ptor)

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