Generic Name / Brand Name Classification Stocks

Indication ( client Specific) Dosage & Frequency Iron deficiency and prophylaxis for iron deficiency anemia Pregnant patient 150 mg PO daily during last 2 trimesters

Mechanism of action

Side Effect / Adverse Reaction

Nursing Responsibilities Includes Health Teaching and implication (Pre, Intra, Post)

FeSO4 (Ferrous sulfate) - For Iron Preparation Classification: Hematologic Drug Anti-anemic

Elevates the serum iron concentration which then helps to form High or trapped in the reticuloendothelial cells for storage and eventual conversion to a usable form of iron.

- temporary staining of the teeth - constipation - black or dark-colored stools - upset stomach - anorexia

Advice patient to take medicine as prescribed. Caution patient to make position changes slowly to minimize orthostatic hypotension. Instruct patient to avoid concurrent use of alcohol or OTC medicine without consulting the physician. Advice patient to consult physician if irregular heartbeat, dyspnea, swelling of hands and feet and hypotension occurs. Inform patient that angina attacks may occur 30 min. after administration due reflex tachycardia. Encourage patient to comply with additional intervention for hypertension like proper diet, regular exercise, and lifestyle changes and stress management.

Generic Name / Brand Name Classification Stocks

Indication ( client Specific) Dosage & Frequency

Mechanism of action

Side Effect / Adverse Reaction

Nursing Responsibilities Includes Health Teaching and implication (Pre, Intra, Post)

GN: Ampicillin Route/ BN: Pricipen Dosage: Cesarean Pharmacologic Section Class: Prophylaxis: Penicillin IV Single Therapeutic dose Class: immediately Antibiotic after cord clamping. ( 2 grams ) Indication: Prophylaxis in cesarean section in certain high risk patients.

Inhibits bacterial cell wall mucopeptide synthesis.

CNS: PRE: Dizziness; fatigue; insomnia; reversible - Obtain patient history, including drug history hyperactivity; neurotoxicity ( lethargy, and known allergies. neuromuscular irritability, hallucinations, - Review results of culture and sensitivity convulsions, seizures) testing, as available. GI: INTRA: Diarrhea; pseudomembranous colitis - Monitor patients condition closely for GU: several hours after administering the first Interstitial nephritis (eg, oliguria, hematuria, dose even when there is no history of pyuria); nephropathy; vaginitis; increase in allergy. creatinine - Notify the physician of any signs or HEMA: symptoms of hypersensitivity or Decrease Hct, Hgb, RBC, WBC, neutrophils, anaphylactic reaction. lymphocytes, platelets; increase monocytes, - Evaluate the skin daily for presence of basophils, eosinophils and platelets. classic ampicillin rash, usually macupapular, DERM: and pruritic and generalized. Urticaria, maculopapular to exfoliative - Monitor for bleeding in patients receiving dermatitis; vesicular eruptions; skin rashes anticoagulant therapy. META: POST: Elevated serum alkaline phosphatase, - Inform the patient to notify the physician glutamic oxaloacetic transminase; reduced immediately if rash develops or if patient has serum albumin and total proteins difficulty of breathing. Other: - Tell the patient to increase fluid intake to Pain at injection site; hyperthermia 2000 3000 ml/day, unless contradicted.

Generic Name / Brand Name Classification Stocks Magnesium sulfate CNS depressant

Indication ( client Specific) Dosage & Frequency Seizures of eclampsia (toxemia of pregnancy) Anticonvulsant: IM = loading dose (10 g of 50% solution [20 mL] divided into 2 doses); maintenance dose (4 5 g of 50% solution [10 mL] q4H deep IM; alternate buttocks IV = loading does (4 g MgSO4 in 250 mL of D5W infuse at 10 mL per minute; maintenance dose (1 2 g per hour by continuous infusion)

Mechanism of action

Side Effect / Adverse Reaction Deep tendon reflexes = absent Decreased urine output Decreases respiratory rate, blood pressure, fetal heart rate (fetal distress) Confusion Neonates = hypotension, hyporeflexia, respiratory depression

Nursing Responsibilities Includes Health Teaching and implication (Pre, Intra, Post) Pregnancy safety: Magnesium sulfate is administered to treat toxemia of pregnancy. It is recommended that the drug not be administered in the 2 hours before delivery, if possible. IV calcium gluconate or calcium chloride should be available as an antagonist to magnesium if needed. Convulsions may occur up to 48 hr after delivery, necessitating continued therapy. The "cure" for toxemia is delivery of the baby. Magnesium must be used with caution in patients with renal failure, since it is cleared by the kidneys and can reach toxic levels easily in those patients. Prophylactic administration of magnesium sulfate for patients with acute myocardial infarction should be considered. Continuously monitor contraction, fetal and maternal heart rate, and blood pressure Monitor patient extremely closely during 1st and 2nd labor because of risk of cervical laceration and uterine rupture and maternal and fetal death.

CNS depressants = potentiate CNS depressant effects of MgSO4 (barbiturates, analgesics, general anesthetics, tranquilizers, and alcohol Neuromuscular blocking agents = concurrent use with MgSO4 will further depress muscular activity.

GN: Oxytocin BN: Syntocinon Pharmacologic Class: Posterior pituitary hormone Therapeutic Class: Uterine-active agent

To induce or stimulate labor 10 units/ml in1ml ampule, vial or syringe incompatible IV solution.

As for endogenous oxytocin, but with little vasopressin activity Stimulates uterine contraction Stimulates lactating breast to eject milk

Hypertension Cardiac output Nausea Vomiting Asphyxia Low APGAR score

Generic Name / Brand Name Classification Stocks GN: Hydralazine BN: Apresoline Cardiovascular System Drug

Indication ( client Specific) Dosage & Frequency Pre-eclampsia /eclampsia 5 mg/dose then 5-10 mg every 20-30 minutes as needed. (TIV)

Mechanism of action

Side Effect / Adverse Reaction CNS: headache, dizziness CV: orthostatic hypotension, tachycardia, arrythmias, angina, palpitations. GI: n/v, diarrhea, anorexia Metabolic: weight gain, sodium retention Skin: rash nausea anorexia vomiting diarrhea

Nursing Responsibilities Includes Health Teaching and implication (Pre, Intra, Post) Assess blood pressure before starting therapy and regularly thereafter. Instruct client to take oral form with meals. Inform client that orthostatic hypotension can be minimized by rising slowly and not changing position suddenly. Tell pt. not to abruptly stop taking drug, but to call the one who prescribed it if adverse reaction occurs. Tell client to limit sodium intake.

Hydralazine Directly relaxes arteriolar smooth muscle Vasodilaion Lowers Blood Pressure

GN: Cefuroxime BN: Ceftin, Zinazef Anti-Infective

Bacterial infections, such as: bronchitis gonorrhea Lyme disease infections of the ears, throat, sinuses, urinary tract, and skin 750 mg cefuroxime sodium I.V q 8 hours for 5 days.

Secondgeneration pephalosporin that inhibits cellwall synthesis, promoting osmotic instability; usually bactericidal.

Determine history of hypersensitivity reactions to cephalosporin, penicillin, and history of allergies, particularly to drugs, before therapy is initiated. Inspect IM and IV injection sites frequently for signs of phlebitis. Report onset of loose stools or diarrhea. Although pseudo membranous colitis. Monitor I&O rates and pattern: Especially important in severely ill patients receiving high doses. Report any significant changes. Prior to reconstitution, protect drug from light. The power and reconstituted drug may darken without affecting potency.

Generic Name / Brand Name Classification Stocks GN: Phenergan BN: Promethazine HCI anti-emetics, antihistamines, sedative/hypnotics

Indication ( client Specific) Dosage & Frequency Preoperative sedation, treatment and prevention of nausea and vomiting, adjunct to anesthesia and analgesia. 25-50 mg (sedation); 10-25mg q 4hr as needed (anti-emetic) (1amp)

Mechanism of action

Side Effect / Adverse Reaction

Nursing Responsibilities Includes Health Teaching and implication (Pre, Intra, Post)

Selectively blocks H1 receptors, diminishing the effects of histamine on cells of the upper respiratory tract and eyes and decreasing the sneezing, mucus production, itching and tearing that accompany allergic reactions. blocks cholinergic receptors in the vomiting center that are believed to mediate the nausea and vomitting caused by gastric irritation.

CNS: neuroleptic malignant syndrome, confusion, disorientation, sedation, dizziness, extrapyramidal reaction, fatigue, insomnia, nervousness; EENT: blurred vision, diplopia, tinnitus; CV: bradycardia, hypertension, hypotension, tachycardia; GI: constipation, druginduced hepatitis, dry mouth; Derm: photosensitivity, rashes; Hema: blood dyscrasias

Monitor BP, pulse and respiratory rate frequently. Assess level of sedation after administration. Assess patient for nausea and vomiting before and after administration. Administer each 25mg slowly over at least 1 hr. Do not give rectal supp or tabs to children younger than 2 years old because of risk of fetal respiratory depressions Give IM injections deep into muscle Do not administer SQ, tissue necrosis may occur Arteriospasms and gangrene of artery may occur when administered intraarterially. Reduce dosage of barbiturates given concurrently within promethazine by least half.

Generic Name / Brand Name Classification Stocks GN: Buscopan BN: Hyoscine Butylbromide Anti-emetic

Indication ( client Specific) Dosage & Frequency To reduce secretions perioperatively. Given via IV, 1mg/ml to promote cervical effacement.

Mechanism of action

Side Effect / Adverse Reaction

Nursing Responsibilities Includes Health Teaching and implication (Pre, Intra, Post) Be alert for adverse reactions and drug interactions. Encourage pt. to void Monitor BP for possible hypotension. Monitor cervical effacement and dilatation.

Hyoscine Butylbromide Inhibits muscarinic actions of acetylcholine in the ANS Affecting neural pathway Relieves spasticity, nausea and vomitting; reduces secretions; and blocks cardiac vagal reflexes. Promotes cervical effacement

CNS: dizziness, headache, restlessness, disorientation, irritability, fever GI: constipation, dry mouth, nausea, vomiting CV: palpitations, tachycardia, flushing EENT: dilated pupils, blurred vision, photophobia, dysphagia GU: urinary hesitancy, urinary retention Skin: rash, dryness

D5LR Class: Hypertonic- Nonpyrogenic, parenteral fluid, electrolyte and nutrient plenisher

- Treatment for persons needing extra calories who cannot tolerate fluid overload. Dosage: 20 drops/ minute

Hypertonic Solutions are those that have an effective osmolality greater than the body fluids. This pulls the fluid into the vascular by osmosis resulting in an increase vascular volume. It raises intravascular osmotic pressure and provides fluid, electrolytes and calories for energy

-Increased serum osmolality -Hypernatremia -Hypokalemia -Altered thermoregulation

- Check vital signs frequently. Report adverse reactions.

Generic Name / Brand Name Classification Stocks GN: Nubain BN: Nalbuphine Hydrochloride Narcotic agonistantagonist analgesic

Indication ( client Specific) Dosage & Frequency

Mechanism of action

Side Effect / Adverse Reaction

Nursing Responsibilities Includes Health Teaching and implication (Pre, Intra, Post) Monitor respiratory rate before and after giving nubain because it causes respiratory depression Monitor I and O to determine if there is excessive fluid loss Monitor Bp before and after administering the medication to prevent any complication

Relief of moderate to Nalbuphine acts as an agonist at specific severe pain opioid receptors in the Preoperative CNS to produce analgesia, as a analgesia, supplement to sedation but also acts surgical anesthesia, to cause and for obstetric hallucinations and is analgesia during labor an antagonist at and delivery receptors Injection 10 mg/ml, 20mg/ml

CNS: Sedation, clamminess, sweating, headache,nervousness, restlessness,depression crying, confusion, faintness, hostility, unusual dreams, hallucinations, euphoria, dysphoria, unreality, dizziness, vertigo,floating feeling, feeling of heaviness, numbness, tingling, flushing, warmth, blurred vision. CV: Hypotension, Hypertension, bradycardia, tachycardia DERMATOLOGIC: Itching, burning, urticaria GI: Nausea,vomiting, cramps,dyspepsia, bitter taste, dry mouth GU: Urinary urgency RESPIRATORY: Respiratory depression, dyspnea, asthma