Professional Documents
Culture Documents
CAREER GOAL:
To pursue career in industrial research. The specific interests are cell biology, musculoskeletal research, gene
therapy, peptide based delivery of siRNA and antibody, stem cell biology, genomics, siRNA, microRNA,
structure and function analysis, engineering of stem cell lines, animal models and basic cancer research.
EDUCATION:
Non-degree course: Boston University School of Medicine in Drug Discovery (2005).
Postdoctoral Fellow: Orthopedic Surgery lab, Boston University School of Medicine, Boston, MA (Sept 2004-
Present)
PhD: Animal Biotechnology, National Biotechnology Centre, Indian Veterinary Research Institute, Izatnagar,
India, 2004.
M.V.Sc.: Animal Biotechnology, National Biotechnology Centre, Indian Veterinary Research Institute,
Izatnagar, India, 2001.
D.V.M.: AVMA listed Nagpur Veterinary College, India, 1998.
PhD THESIS:
Identification of Novel Nuclear Localization Signal from IBD Virus for Development of Peptide Based
Delivery System
MVSc THESIS:
Sequence Analysis of Very Virulent Infectious Bursal Disease Virus of Poultry
PATENT:
Development of reagent for intracellular delivery of small molecule such as siRNA and antibody.
An Artificially Synthesized Peptide. Dr. Satish Kumar, Dr. Manish Virendrasingh Bais, Dr. Ranjit Singh
Kataria Dr. Mahendra Pal Yadav
Pub. No.: WO/2008/041047
International Application No: PCT/IB2006/002786
Publication Date: 10.04.2008
International Filing Date: 06.10.2006
ABSTRACTS:
1. Bais M V, Barnes GL, Gerstenfeld LC, Einhorn TA Loss of Osteogenic Differentiation by Knock- Down of
Endogenous BMP-2 Expression Can Be Rescued by the Exogenous Administration of BMP-7 and is
Mediated by Increased Osterix Activity. 54th Annual Meeting of the ORS March 2-5, 2008 San Franscisco,
CA
2. Bais M V., Wigner N., Young M., Toholka R., Graves D.,. Morgan E. F,. Gerstenfeld L. C,. Einhorn T. A
Dependence of Post Natal Osteogenic Differentiation on BMP2: Dissection of Osteogenic Lineage
Commitment by Lentivirus BMP2 shRNA ex vivo and in vivo. 30th ASBMR annual meeting Sept 12-16,
2008 Montreal, Canada
3. Bais MV, Mclean J, Sabastiani P, Young M, Smith T, Wigner N, Kotton DN, Einhorn TA, and
Gerstenfeld LC. Induction of embryonic stem cell-related pluripotency genes in in Post Natal Stem Cells
during Fracture Healing. 30th ASBMR annual meeting Sept 12-16, 2008 Montreal, Canada
4. Bais M.V,.Kataria R.S, Tiwari A. K, Indervesh,.Das S. K, and.Suryanarayana V. V.S. Sequence analysis of
segment A encoding polyprotein of field isolate of infectious bursal disease virus. Abstract presented at
IXth Annual conference of IAAVR and national Symposium on “concepts in Sustainable livestock
production and health in new Millennium (2002).”
5. Bais M.V, Satish Kumar,.Tiwari A.K, Kataria R.S.and.Viswas K.N “A peptide molecule, ‘Rath’, as a
machine to deliver oligonucleotide and antibody in the cells” (Abstract presentation at International
symphosia “Molecules, Machines and Network” from January 6-9, 2004 at Banglore, India).
6. Bais M.V, Satish Kumar,.Tiwari A.K,.Kataria R.S and.Viswas K.N “Designing a peptide vector for
transfection of plasmid in mammalian cells” presented at National Symphosia on Cellular and Molecular
Biophysics; Jan 14-17,2004 at National institute of Mental Health and Neuro Sciences at Banglore, India.
REFERENCES:
1. Dr. Thomas Einhorn, MD
Professor, Biomedical Engineering
Professor and Chairman, Orthopedic Surgery
720 Harrison avenue, Suite 805 Boston MA 02118
phone: (617) 638-8435
fax: (617) 638-8493
Email: teinhorn@bu.edu
2. Louis C. Gerstenfeld, Ph.D
Associate Professor, Department of Orthopedic Surgery;
Director of Musculoskeletal Research Laboratory
715 Albany St., R-2, Boston MA 02118-2394
617/414-1660
Email: lgersten@bu.edu
3. Darrell N. Kotton, M.D.
The Pulmonary Center, Boston University School of Medicine
715 Albany St., R-304, Boston, MA 02118
Office: 617-638-4860
Email:dkotton@bu.edu
www.kottonlab.com