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Subject: Radiology

Topic: Um..?
Lecturer: The usual
Shifting /Date: 2nd shifting, August 9 2008
Trans group: Chicken Naguits :D

Trauma classification • Up to 95% of patients with bladder rupture


• Grade 1 present with gross hematuria
o subscapular hematoma non-expanding • The susceptibility of bladder to injury is
o contusions and small infarcts dependent on degree of distention, a distended
o no parenchymal laceration urinary bladder is much more prone to injury
• Grade II than a nearly empty one
o less than 1 cm laceration • Urine extravasation, whether intraperitoneal or
o non-expanding perirenal hematoma extraperitoneal, is dependent on the location of
• Grade III the bladder. Intraperitoneal rupture often
o greater than 1 cm laceration results from a direct blow to a distended
o not extending to collecting system bladder
• Grade IV • Delayed scans may help display extravasated
o laceration with urinary extravasation urine
o main renal artery or vein injury with
Adrenal Adenoma
contained bleed
• Grade V • Incidence in the population is 2-8%
o main renal artery thrombosis • Diagnosis is often made as an incidental finding
o shattered kidney on CT examination
o renal hilar injury with devascularization of • In patient with no known primary, an adrenal
kidney mass is almost always a benign adenoma
o avulsion at UPJ • In a patient with a known neoplasm, especially
lung cancer, an adrenal mass is problematic
CT is highly useful for: and diagnosing a metastasis versus and
1. Diagnosing and staging renal injuries adenoma is critical for prognosis
2. Determining the depth of cortical • CT findings
lacerations o Size greater than 4 cm tend to be
3. The quantity of devascularized renal tissue metastases or adrenal carcinoma
4. The status of the renal collecting system - heterogeneous appearance and irregular
5. The extent of peri-renal hemorrhage shape are malignant characteristics
o Homogeneous and smooth are benign
Clas Criteria characteristics
s - intracellular lipid in adenoma results in low
Contusions, small attenuation on CT
corticomedullary o Little intracytoplasmic fat in metastases
I Lacerations that do not results in high attenuation on non-enhanced
communicate with the collecting CT
system o Non-enhanced CT (NECT)
II Laceration that communicates - threshold 10 HU
with the collection system - sensitivity 79%, specificity 96%
III Shattered kidney, injury to the o Contrast-enhanced CT (CECT)
vascular pedicle -because majority of CT examinations in
IV UPJ avulsion, laceration of the oncology use IV contrast, the % washout is
renal pelvis useful after 10 minutes.
- adenomas have greater than 50%
Bladder washout after 10 minutes
-washout can also be used on adrenal
• Occurs in association with blunt pelvic trauma,
masses that measure >10 HU on NECT
pelvic fractures or penetrating injuries
- alternative is to do MR or PET
• Gross hematuria almost always accompanies
bladder rupture

MARY YVETTE ALLAIN TINA RALPH SHERYL BART HEINRICH PIPOY KC JAM CECILLE DENESSE VINCE HOOPS CES XTIAN LAINEY RIZ KIX EZRA GOLDIE BUFF MONA AM MAAN ADI KC
PENG KARLA ALPHE AARON KYTH ANNE EISA KRING CANDY ISAY MARCO JOSHUA FARS RAIN JASSIE MIKA SHAR ERIKA MACKY VIKI JOAN PREI KATE BAM AMS HANNAH MEMAY PAU
RACHE ESTHER JOEL GLENN TONI
Subject: Radiology
Topic:
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MR findings: • Coronal and sagittal images may be helpful in
• Chemical Shift determining adrenal origin of the mass, thus
- most sensitive method for differentiating differentiating it from renal cell carcinoma or
adenomas from metastases hepatocellular carcinoma, especially if CT is
- sensitivity 81-100%, specificity 94-100% equivocal
- the difference in resonance rate of protons in
fat and water is exploited in chemical shift CT findings
-- intracellular lipid and water in same voxel • Large mass (>4 cm)
result in • Central necrosis or hemorrhage
summation of signal on “in-phase” and • Heterogeneous enhancement
canceling out of • Invasion into adjacent structures
signal on “out of phase”
• Venous extravasation into the renal vein or
• Spleen or muscle is used as an internal
inferior vena cave
standard to visually quantify signal drop-off
- liver is not a reliable standard because of
Adrenal metastases
steatosis
• Unilateral adrenal mass or enlargement
Adrenocortical carcinoma • Small masses (<1 cm)
• Rare malignancy with a poor prognosis o Adenoma
• Reported incidence: 2 cases per million persons o Ganglioneuroma
o Hyperplasia
• Tumors frequently are large, measuring 4-10
o Metastasis
cm in cross-sectional diameter
o Pheochromocytoma
• Arise from the adrenal cortex
• Large masses (>4 cm)
• Bilateral in up to 10% of patients
o Carcinoma of adrenal cortex
• Approximately 50-80% are functional tumors,
o Cyst or pseudocyst
with most causing Cushing syndrome
o Hematoma
• Sign and symptoms
o Infection
o A large palpable mass, abdominal pain, or
o Inflammation (eg, tuberculosis,
Cushing syndrome
histoplasmosis)
o Cushing syndrome is the most common
o Metastasis (eg, lung or breast related)
clinical presentation in adults with adrenal
o Myelolipoma
cortical carcinoma, although
o Neuroblastoma
o Patients can present with virilization,
o Ganglioneuroblastoma or ganglioneuroma
feminization, precocious puberty, or Conn
syndrome o Pheochromocytoma (eg, multiple endocrine
o In children, the most common clinical neoplasia)
presentation is virilization , followed by
Cushing syndrome
• Endocrine syndromes associated with Bilateral adrenal enlargement
adrenocortical carcinoma Common causes: hemorrhage (eg in infants,
o Cushing syndrome trauma, bleeding disorder), histoplasmosis,
hyperplasia, metastasis (eg, lung or breast
o Virilization and precocious puberty
related), neuroblastoma, and tuberculosis
o Feminization
o Primary hyperaldosteronism Uncommon causes: Addison disease, adenomas,
amyloidosis, carcinomas (eg, multiple, primary),
MRI findings: infection (ie, others), lymphoma,
• A large mass pheochromocytoma (multiple endocrine neoplasia),
- lower signal intensity than the liver on T1- and Wolman disease (eg, familial xanthomatosis)
weighted images and
- higher signal intensity than the liver on T2- CT Findings
weighted images • Appear as focal masses or distortion of the
- often, the tumor demonstrates contour of the adrenal gland
heterogeneously hyperintensity on T1- and T2- • Smaller than 3 cm may be homogenous
weighted images, due to the central necrosis
• Large lesions may have central necrosis or
and hemorrhage
hemorrhage. These lesions are heterogenous
Subject: Radiology
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and may have thick enhancing rims. They may
also invade contiguous organs such as the
kidneys.
• Attenuation values of less than 10 HU on
unenhanced
Left: T1-weighted, a mixed isointense-to-
MRI Findings hypointense right adrenal mass
• Are usually hypointense on T1-weighted images Right: T2-weighted, the right adrenal tumor has
and high signal intensity
• Relatively hyperintense on T2-weighted images
• The exception is metastatic melanoma, which Pheochromocytomas
may be bright on T1-weighted images
CT Findings
• Occasionally, lesions may remain hyperintense
• Large tumors (often > 3 cm)
on long-echo time T2-weighted images,
mimicking pheochromocytomas • They are usually round or oval masses with an
attenuation similar to that of the liver
• Larger lesions frequently demonstrate necrosis,
CASE: 43 year-old women with hypertension hemorrhage, and fluid-fluid levels
• A middle aged woman presented to her primary • As a result, they often appear inhomogenous
care physician with hypertension and episode • Calcification is rare, but it is reported
sweating. She was referred to a urologist who
obtained a 24 hour urinary vanillymandelic acid MRIs
(VMA) which was elevated • Usually hypointense or isointense relative to
the liver on T1-weighted spin-echo (SE) images,
and
• They are highly intense on T2-weighted SE
images
• The reason for this difference is unknown, but
likely results from the high water content in
cellular homogenous tumors or the high water
content in necrotic regions
• Tumors that have bled show the features
typical of hemorrhage, depending on the age of
CASE: 35 year-old women with HPN the hemorrhage
• A large, right-sided, inhomogenous, adrenal
mass with a central area of low attenuation
that represents hemorrhage or necrosis Normal Uterine Size:
By ultrasound, the normal postmenarchal
nulliparous uterus is 5-8 cm in length, 1.5-3 cm
thick, 2.5-5 cm wide.

Myometrium:
The normal myometrium is hypoechoic,
homogenous, and reasonably well demarcated
from the endometrial echos

Endometrial Structure:
The endometrium consists of a constant basal
layer (basalis), and a cycling functional layer
(functionalis). The functional layer includes a thin
compactum layer and a thick spongiosum layer.
Subject: Radiology
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sac is often considered abnormal, but
occasional normal pregnancies do not show
yolk sac up to 20mm.
Name Of Phase Days
Menstrual Phase 1-4 • By lower resolution abdominal scanning, a sac
Follicular phase 4-14 > 20mm MSD with no yolk sac is abnormal.
(aka proliferative
phase) Vaginal scanning to improve certainty should
Ovulation (not a 14 be done.
phase, but an
event dividing
phases
Luteal phase (aka 15-26
secretory phase)
Ischemic phase 27-28
(some sources
group this with
secretory phase)

Phase Days Thickness


Menstrual 1-4 Thin
phase
Proliferativ 4-14 Trilaminar
e Phase
Secretory 15-28 Thick
phase

Early pregnancy
• Gestational Sac first appears in the substance
of the deciduas (intradecidual) at 4.5 weeks,
and should be seen virtually in all normal 5
week intrauterine pregnancies. Abnormal gestational sac size (3cm) neither
a yolk sac not an embryo is identified.
• The yolk sac is a definite evidence of a true
gestational sac, first seen at 5 weeks. It is a
landmark to the early embryo, which develops
along its outer margin. Yolk sac should be seen
when the sac is 8-10mm. MSD by vaginal
probe, or 20mm. MSD by abdominal probe.

• By vaginal probe high resolution scanning, the


embryo is first seen between 5.7 – 6.1 weeks
with heartbeat appearing at 6.2 weeks. Small
normal embryos may not have a heartbeat.
Embryo should be seen by high resolution scan
at 18mm MSD, or 25mm MSD by abdominal
scan.

Anembryonic Gestation (Blighted Ovum)

• By high resolution vaginal scanning, a sac >


13mm MSD (mean sac diameter) with no yolk
Subject: Radiology
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Obstetrical Ultrasound Measurements

• Gestational Sac

Associated findings in threatened abortion o The first element to be measured is the


gestational sac of pregnancy. It is measured
• Subchorionic bleeding in three dimensions, and the average—the
MSD is used for estimating the gestational
o Often visible as endometrial fluid surrounding
age.
the external (deciduas capsularis) aspect of
the gestational sac. As long as the placental o It is useful between 5-8 menstrual weeks
(decidua vera) interface of the gestational with accuracy of +/- 0.5 week (95% CI).
sac and deciduas remain intact, the
pregnancy often continues. o As a rough rule of thumb, the MSD + 30 =
Menstrual Age in days.
o From the standpoint of hemorrhage volume
estimated using-- • Embryonic Crown Length

 length (cm) x height (cm) x depth (cm) x o The length of the embryo in the longest axis
0.52 = volume ml (excluding the yolk sac) constitutes the
crown rump length.
less than 75-200mL is often associated
with continued development. o This is among the best documented
parameters to date the embryo, with
• Slow heartbeat accuracy of +/- 3-5days.

o Embryonic heart rate <85 bpm is a negative o As a rule of thumb, the CRL +6.5 =
prognostic sign, but is less reliable in small Menstrual age in weeks
embryos
• Biparietal diameter (BPD)
• Small Sac
o The transverse width of the head at it’s
o When the mean sac diameter (MSD) exceeds widest, usually recognized by a symmetric
crown rump length (CRL) by less than 5mm, measure from the leading edge to leading
loss rate is 80%. However this “small sac” edge of the bones, because this leading
sign occurs in only 2% of the time. interface is most distinct.

o The BPD best used after 12 weeks. Accuracy


is +/- 1.1 week 14-20 weeks, +/- 1.6 weeks
Incomplete Spontaneous Abortion (embryo
20-26 weeks, +/- 2.4 week 26-30 weeks, and
dead)
+/- 3.4 weeks after 30 weeks.
• In many cases, embryo has already died.
• Head Circumference
Persistent chorionic function maintains a
positive HCG assay o A measurement which considers both
transverse (BPD) and front to back (APD) will
• Expulsion of the sac is often delayed several
be more accurate. This combined
days, though it may be seen to slowly migrate
measurement is called the head
from the initial fundal location toward the
circumference. A true circumference is not
uterine cervix.
actually measured through. The BPD and
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APD (anterior/posterior diameter) are
measured and the circumference of the
result in oval calculated Ang mga sumusunod ay mga hango lamang sa
mga sinabi ni doc na naitala po namin 
o If the machine does not calculate Head
Circumference, you can do it easily with the Delayed Film – used to determine if there is a
nephrogram
formula:
Case of Hydronephrosis:
(APD + BPD)/2 X 3.14 = Head
You have a bladder which has a smooth margin
Circumference outline, then the left kidney is now visualized, this
is the post void the distal third of the ureter this is
• Femur Length one hour delay. So what is the purpose of having a
delayed film? We could appreciate if there is a
o The femur length is a repeatable nephrogram in the left kidney. So until the three
measurement with accuracy similar to the hour delay there is no evidence of nephrogram.
BPD. It is affected by skeleton dysplasia, but The patient was ultrasound, the left kidney is very
since these are rare, it is reliable small it was 8.7 with cortical thickness of 0.8, so
this is a medical renal disease. So this is the rt
measurement which confirms measurements
kidney showing you the hydronephrosis. In that
of the head. It is best measured after 14 case the left kidney is not malfunctioning.
weeks.
Case of Enlarged Kidney:
• Abdominal Circumference Another patient showing you calcification in the left
pelvic region there are no calcifications in the
o The abdominal circumference is another region of the renal shadow as well as in the areas
circumference estimate made by averaging of the ureters. So this is a one minute film showing
the anterior-posture and transverse you a right kidney with a normal pelvocalyceal
system, the left kidney show you a urethrogram
diameters times 3.14. it is made at the
and the left kidney is enlarged.
widest point in the abdomen, through the
liver at the level of the left portal vein or There’s hydronephrosis in the dilated ureter to the
stomach. area of the uretero pelvic junction so there is a
stone.
o Fetal Breathing Movements: Complex Reflex,
Sensitive but not Specific, False + in sleep. Normal Ultasound Findings:
Normal Size: 9-12
o Fetal Trunk and Extremities Movements: Presence of corticomedullary differentiation - the
Moderate Complexity less Sensitive, more medulla is usu. whiter or hyperechogenicicity
compared to the cortex.
specific All pregnancies 26 weeks or more
Normal thickness of the urinary bladder: 0.3cm or
must show motion during routine ultrasound, 3mm for a well distended bladder; for a post ovoid
if not, further evaluation id done, First bladder it’s 0.5cm of 5mm
Acoustic Stimulation, an if negative, Formal
Biophysical Profile. So how will you know if it’s a fully
distended/underfield bladder? The bladder should
o Fetal tone: Simple maintenance of flexion have 200cc, if it’s less than 250cc it’s underfield in
“Fetal Position” posture. Relatively adults.
insensitive, but ominously specific often for
Case of Nephrolithiasis
more advanced distress.
In the kidney there is shadowing echogenicity,
there is nephrolithiasis.
o Amniotic fluid volume: not neural reflex, but
a physiologic reflection of uteri ne production Case of Acute Renal Failure
and uterine retention. Multiple shadowy echogenicity in the kidney - This
is a staghorn calculi; acute renal failure because
the kidney is around 7.7. So once the kidney is
Subject: Radiology
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small and there is no cortical differentiation mean • Superficial cortical lacerations less than 1
chronic medical renal disease. Then you have to cm in depth without collecting system injury
correlate it with the serum creatinine. Serum Grade 3
creatinine is elevated, so most likely the px is • Renal lacerations greater than 1 cm in
either acute renal failure or in a chronic stage. depth that do not involve the collecting
system
Case of Acute Renal Failure Grade 4
This is the left kidney, it’s small because it’s shows • Renal lacerations extending through the
8.9 but still there is cortical differentiation. kidney into the collecting system
• Injuries involving the main renal artery or
Case of Mild Pelvocalceal/Hydronephrosis
vein with contained hemorrhage
Ureter
• Segmental infarctions without associated
Fluid filled on urine field. So the patient has
lithotripsy there is no evidence of stones in the lacerations
kidney but the kidney shows hydronehprosis so • Expanding subcapsular hematomas
possibly the remaining stones were put in the compressing the kidney
distal or proximal ureter producing hydronephrosis Grade 5
 obstruction. So this is an example of a • Shattered or devascularized kidney
hydronephrosis ureter. Somehow you have a • Ureteropelvic avulsions
thinned out cortex and you have dilated proximal • Complete laceration or thrombus of the
ureter. main renal artery or vein

Limitation of Ultrasound: If you have a very gassy CT Scan useful for genitourinary dx or staging
abdomen you could not visualize the distal ureters. injuries, depth of the cortical laceration, extent of
perirenal hemorrhage, devascularize tissue,
Case of Perirenal Hematoma collecting system.
One of the complication of a lithotripsy is a
hematoma. The patient has a perirenal hematoma. CT Sonoram is a plain CT Scan which is able to
Usually the px will have utz everyday to monitor if visualize if there are pancake calcifications in the
it’s increasing or decreasing. Increasing  surgeon GUT. So in px with a very high serum creatinine
will evacuate hematoma. and they want to know if there is stone because of
microscopic hematuria, CT sonogram can be done.
Case of Angiomyolipoma
Angiomyolipoma so this is fat. In this case the px Case of Phechromocytoma
has a double collecting system, forming the entire On UTZ adrenals are not visualized unless they are
echogenicity meaning the single collecting system enlarged. If it’s >1cm, it’s enlarged. The normal
in this case we now have as 2, which is a normal structure is either a “Y’ or a “V”. if patient has lung
variant. CA, CT scan usually includes adrenals to check for
metastasis. Also used for unexplained elevated
Case of Cystitis BP, so px has pheochromocytoma.
You have a very thick walled, patient has cystitis.
Most common lesion in the adrenals is the
Case of Kidney Abscess adenoma.
Abnormal kidney has an abscess in the fascia. If px
has prev. hx of trauma, could be hematoma. If px
has prev. hx of lithotripsy also could be hematoma.

Grading of Trauma
Grade 1
• Hematuria with normal imaging studies
• Contusions
• Nonexpanding subcapsular hematomas
Grade 2
• Nonexpanding perinephric hematomas
confined to the retroperitoneum
Subject: Radiology
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