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Topic: Um..?
Lecturer: The usual
Shifting /Date: 2nd shifting, August 9 2008
Trans group: Chicken Naguits :D
MARY YVETTE ALLAIN TINA RALPH SHERYL BART HEINRICH PIPOY KC JAM CECILLE DENESSE VINCE HOOPS CES XTIAN LAINEY RIZ KIX EZRA GOLDIE BUFF MONA AM MAAN ADI KC
PENG KARLA ALPHE AARON KYTH ANNE EISA KRING CANDY ISAY MARCO JOSHUA FARS RAIN JASSIE MIKA SHAR ERIKA MACKY VIKI JOAN PREI KATE BAM AMS HANNAH MEMAY PAU
RACHE ESTHER JOEL GLENN TONI
Subject: Radiology
Topic:
Page 2 of 8
MR findings: • Coronal and sagittal images may be helpful in
• Chemical Shift determining adrenal origin of the mass, thus
- most sensitive method for differentiating differentiating it from renal cell carcinoma or
adenomas from metastases hepatocellular carcinoma, especially if CT is
- sensitivity 81-100%, specificity 94-100% equivocal
- the difference in resonance rate of protons in
fat and water is exploited in chemical shift CT findings
-- intracellular lipid and water in same voxel • Large mass (>4 cm)
result in • Central necrosis or hemorrhage
summation of signal on “in-phase” and • Heterogeneous enhancement
canceling out of • Invasion into adjacent structures
signal on “out of phase”
• Venous extravasation into the renal vein or
• Spleen or muscle is used as an internal
inferior vena cave
standard to visually quantify signal drop-off
- liver is not a reliable standard because of
Adrenal metastases
steatosis
• Unilateral adrenal mass or enlargement
Adrenocortical carcinoma • Small masses (<1 cm)
• Rare malignancy with a poor prognosis o Adenoma
• Reported incidence: 2 cases per million persons o Ganglioneuroma
o Hyperplasia
• Tumors frequently are large, measuring 4-10
o Metastasis
cm in cross-sectional diameter
o Pheochromocytoma
• Arise from the adrenal cortex
• Large masses (>4 cm)
• Bilateral in up to 10% of patients
o Carcinoma of adrenal cortex
• Approximately 50-80% are functional tumors,
o Cyst or pseudocyst
with most causing Cushing syndrome
o Hematoma
• Sign and symptoms
o Infection
o A large palpable mass, abdominal pain, or
o Inflammation (eg, tuberculosis,
Cushing syndrome
histoplasmosis)
o Cushing syndrome is the most common
o Metastasis (eg, lung or breast related)
clinical presentation in adults with adrenal
o Myelolipoma
cortical carcinoma, although
o Neuroblastoma
o Patients can present with virilization,
o Ganglioneuroblastoma or ganglioneuroma
feminization, precocious puberty, or Conn
syndrome o Pheochromocytoma (eg, multiple endocrine
o In children, the most common clinical neoplasia)
presentation is virilization , followed by
Cushing syndrome
• Endocrine syndromes associated with Bilateral adrenal enlargement
adrenocortical carcinoma Common causes: hemorrhage (eg in infants,
o Cushing syndrome trauma, bleeding disorder), histoplasmosis,
hyperplasia, metastasis (eg, lung or breast
o Virilization and precocious puberty
related), neuroblastoma, and tuberculosis
o Feminization
o Primary hyperaldosteronism Uncommon causes: Addison disease, adenomas,
amyloidosis, carcinomas (eg, multiple, primary),
MRI findings: infection (ie, others), lymphoma,
• A large mass pheochromocytoma (multiple endocrine neoplasia),
- lower signal intensity than the liver on T1- and Wolman disease (eg, familial xanthomatosis)
weighted images and
- higher signal intensity than the liver on T2- CT Findings
weighted images • Appear as focal masses or distortion of the
- often, the tumor demonstrates contour of the adrenal gland
heterogeneously hyperintensity on T1- and T2- • Smaller than 3 cm may be homogenous
weighted images, due to the central necrosis
• Large lesions may have central necrosis or
and hemorrhage
hemorrhage. These lesions are heterogenous
Subject: Radiology
Topic:
Page 3 of 8
and may have thick enhancing rims. They may
also invade contiguous organs such as the
kidneys.
• Attenuation values of less than 10 HU on
unenhanced
Left: T1-weighted, a mixed isointense-to-
MRI Findings hypointense right adrenal mass
• Are usually hypointense on T1-weighted images Right: T2-weighted, the right adrenal tumor has
and high signal intensity
• Relatively hyperintense on T2-weighted images
• The exception is metastatic melanoma, which Pheochromocytomas
may be bright on T1-weighted images
CT Findings
• Occasionally, lesions may remain hyperintense
• Large tumors (often > 3 cm)
on long-echo time T2-weighted images,
mimicking pheochromocytomas • They are usually round or oval masses with an
attenuation similar to that of the liver
• Larger lesions frequently demonstrate necrosis,
CASE: 43 year-old women with hypertension hemorrhage, and fluid-fluid levels
• A middle aged woman presented to her primary • As a result, they often appear inhomogenous
care physician with hypertension and episode • Calcification is rare, but it is reported
sweating. She was referred to a urologist who
obtained a 24 hour urinary vanillymandelic acid MRIs
(VMA) which was elevated • Usually hypointense or isointense relative to
the liver on T1-weighted spin-echo (SE) images,
and
• They are highly intense on T2-weighted SE
images
• The reason for this difference is unknown, but
likely results from the high water content in
cellular homogenous tumors or the high water
content in necrotic regions
• Tumors that have bled show the features
typical of hemorrhage, depending on the age of
CASE: 35 year-old women with HPN the hemorrhage
• A large, right-sided, inhomogenous, adrenal
mass with a central area of low attenuation
that represents hemorrhage or necrosis Normal Uterine Size:
By ultrasound, the normal postmenarchal
nulliparous uterus is 5-8 cm in length, 1.5-3 cm
thick, 2.5-5 cm wide.
Myometrium:
The normal myometrium is hypoechoic,
homogenous, and reasonably well demarcated
from the endometrial echos
Endometrial Structure:
The endometrium consists of a constant basal
layer (basalis), and a cycling functional layer
(functionalis). The functional layer includes a thin
compactum layer and a thick spongiosum layer.
Subject: Radiology
Topic:
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sac is often considered abnormal, but
occasional normal pregnancies do not show
yolk sac up to 20mm.
Name Of Phase Days
Menstrual Phase 1-4 • By lower resolution abdominal scanning, a sac
Follicular phase 4-14 > 20mm MSD with no yolk sac is abnormal.
(aka proliferative
phase) Vaginal scanning to improve certainty should
Ovulation (not a 14 be done.
phase, but an
event dividing
phases
Luteal phase (aka 15-26
secretory phase)
Ischemic phase 27-28
(some sources
group this with
secretory phase)
Early pregnancy
• Gestational Sac first appears in the substance
of the deciduas (intradecidual) at 4.5 weeks,
and should be seen virtually in all normal 5
week intrauterine pregnancies. Abnormal gestational sac size (3cm) neither
a yolk sac not an embryo is identified.
• The yolk sac is a definite evidence of a true
gestational sac, first seen at 5 weeks. It is a
landmark to the early embryo, which develops
along its outer margin. Yolk sac should be seen
when the sac is 8-10mm. MSD by vaginal
probe, or 20mm. MSD by abdominal probe.
• Gestational Sac
length (cm) x height (cm) x depth (cm) x o The length of the embryo in the longest axis
0.52 = volume ml (excluding the yolk sac) constitutes the
crown rump length.
less than 75-200mL is often associated
with continued development. o This is among the best documented
parameters to date the embryo, with
• Slow heartbeat accuracy of +/- 3-5days.
o Embryonic heart rate <85 bpm is a negative o As a rule of thumb, the CRL +6.5 =
prognostic sign, but is less reliable in small Menstrual age in weeks
embryos
• Biparietal diameter (BPD)
• Small Sac
o The transverse width of the head at it’s
o When the mean sac diameter (MSD) exceeds widest, usually recognized by a symmetric
crown rump length (CRL) by less than 5mm, measure from the leading edge to leading
loss rate is 80%. However this “small sac” edge of the bones, because this leading
sign occurs in only 2% of the time. interface is most distinct.
Limitation of Ultrasound: If you have a very gassy CT Scan useful for genitourinary dx or staging
abdomen you could not visualize the distal ureters. injuries, depth of the cortical laceration, extent of
perirenal hemorrhage, devascularize tissue,
Case of Perirenal Hematoma collecting system.
One of the complication of a lithotripsy is a
hematoma. The patient has a perirenal hematoma. CT Sonoram is a plain CT Scan which is able to
Usually the px will have utz everyday to monitor if visualize if there are pancake calcifications in the
it’s increasing or decreasing. Increasing surgeon GUT. So in px with a very high serum creatinine
will evacuate hematoma. and they want to know if there is stone because of
microscopic hematuria, CT sonogram can be done.
Case of Angiomyolipoma
Angiomyolipoma so this is fat. In this case the px Case of Phechromocytoma
has a double collecting system, forming the entire On UTZ adrenals are not visualized unless they are
echogenicity meaning the single collecting system enlarged. If it’s >1cm, it’s enlarged. The normal
in this case we now have as 2, which is a normal structure is either a “Y’ or a “V”. if patient has lung
variant. CA, CT scan usually includes adrenals to check for
metastasis. Also used for unexplained elevated
Case of Cystitis BP, so px has pheochromocytoma.
You have a very thick walled, patient has cystitis.
Most common lesion in the adrenals is the
Case of Kidney Abscess adenoma.
Abnormal kidney has an abscess in the fascia. If px
has prev. hx of trauma, could be hematoma. If px
has prev. hx of lithotripsy also could be hematoma.
Grading of Trauma
Grade 1
• Hematuria with normal imaging studies
• Contusions
• Nonexpanding subcapsular hematomas
Grade 2
• Nonexpanding perinephric hematomas
confined to the retroperitoneum
Subject: Radiology
Topic:
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