Drug Order Generic Name: Amlodipine Brand Name: Norvasc Classificati on: -Calcium channelblocker -Antianginal Drug Antihyperte

nsive

Mechanis m of Action Inhibits the movement of calcium ions across the membrane s of cardiac and arterial muscle cells; inhibits transmemb rane calcium flow, which results in the depression of impulse formation in specialized cardiac pacemaker cells, slowing of the velocity of conduction of the cardiac impulse, depression of myocardial contractilit y, and dilation of coronary arteries and

Indication Angina pectoris due to coronary artery Spasm, Chronic stable angina, alone or in combinatio n with other agents, Essential hypertensio n, alone or in combinatio n with other antihyperte nsive

Contraindication The presence of any allergies to nitrates. These drugs are also contraindicated in the following conditions: Sever e anemia, head trauma or hemorrhage, preg nancy and lactation.

Adverse Effect CNS: Dizziness, lightheaded ness, headache, asthenia, fatigue, lethargy CV: Peripheral edema, arrhythmias Dermatolog ic: Flushing, rash GI: Nausea, abdominal Discomfort

Nursing Responsibil ities BEFORE: -Obtain patients history to allergy of amlodipine. -Assess vital signs before therapy. DURING: -Monitor patients BP, cardiac rhythm -Monitor intake and output. AFTER: -Monitor vital signs. -Be alert for adverse effect. >Advise patient to take medication as directed, even if feeling well. >Take missed doses as soon as possible unless almost time for next dose; do

arterioles and peripheral arterioles; these effects lead to decreased cardiac work, decreased cardiac oxygen consumpti on, and in patients with vasospastic angina, increased delivery of oxygen to cardiac cells.

not double doses. > Caution patient to change positions slowly to minimize orthostatic hypotensio n. > Advise patient to notify health care professiona l if irregular heartbeats, dyspnea, swelling of hands and feet, pronounced dizziness, nausea, constipatio n, or hypotensio n occurs or if headache is severe or persistent. > Caution patient to wear protective clothing and use sunscreen to prevent photosensit ivity reactions.

Drug Name Generic Name: Azithromyci n Brand Name: Zmax Classificati on: Antibiotic Dose: 500mg

Mechanis m of Action Bacteriosta tic or bactericida l insusceptib le bacteria.

Indication -Treatment of lower respiratory infections: Acute bacterial exacerbatio ns of COPD due to Haemophil us influenzae, Moraxella catarrhalis, Streptococ cus pneumonia e; community -acquired pneumonia due to S. pneumonia e, H. influenzae -Treatment of lower respiratory infections: Streptococ cal pharyngitis and tonsillitis due to Streptococ cus pyogenes in those who cannot take

Contraindication Adverse Effect -Contraindicated with hypersensitivity to azithromycin, erythromycin, or any macrolide antibiotic. -Use cautiously with gonorrhea or syphilis, pseudomembran ous colitis, hepatic or renal impairment, lactation. Mild to moderate nausea, vomiting, abdominal pain, dyspepsia, flatulence, diarrhea, cramping; angioede ma, cholestati c jaundice; dizziness, headache, vertigo, somnolen ce; transient elevations of liver enzyme values.

Nursing Responsibilities -History: Hypersensitivity to azithromycin, erythromycin, or any macrolide antibiotic; gonorrhea or syphilis, pseudomembran ous colitis, hepatic or renal impairment, lactation -Physical: Site of infection; skin color, lesions; orientation, GI output, bowel sounds, liver evaluation; culture and sensitivity tests of infection, urinalysis, LFTs, renal function tests -Culture site of infection before therapy. -Administer on an empty stomach 1 hr before or 23 hr after meals. Food affects the absorption of this drug. -Take the full

penicillins

course prescribed. Do not take with antacids. Tablets and oral suspension can be taken with or without food. -Prepare Zmax by adding 60 mL water to bottle, shake well. Counsel patients -You may experience these side effects: Stomach cramping, discomfort, diarrhea; fatigue, headache (medication may help); additional infections in the mouth or vagina (consult with health care provider for treatment). -Report severe or watery diarrhea, severe nausea or vomiting, rash or itching, mouth sores, vaginal sores.

Drug Order Generic Name: Ceftriaxon e Brand Name: Forgram Classificat ion: Cephalosp orins Dose: 1g

Mechanism of Action Works by inhibiting the mucopeptide synthesis in the bacterial cell wall. The beta-lactam moiety of Ceftriaxone binds to carboxypepti dases, endopeptidas es, and transpeptidas es in the bacterial cytoplasmic membrane. These enzymes are involved in cell-wall synthesis and cell division. By binding to these enzymes, Ceftriaxone results in the formation of defective cell walls and cell death.

Indication Treatment of infections of the lower respirator y tract, acute bacterial otitis media, skin & skin structure infection, UTI, uncomplic ated gonorrhea, pelvic inflammat ory disease, bacterial septicemia , bone & joint infections, intraabdominal infections, meningitis

Contraindic ation Hypersensit ivity to cephalospor ins. Hypersensit ivity to lidocaine (IM inj)

Adverse Effect -Pain -Induration -Phlebitis -Rash -Diarrhea Thrombocyt osis -Leucopenia -Glossitis Respiratory superinfecti ons

Nursing Responsibilities -Assess patients previous sensitivity reaction to penicillin or other cephalosphorins. -Assess patient for signs and symptoms of infection before and during the treatment -Obtain C&S before beginning drug therapy to identify if correct treatment has been initiated. -Assess for allergic reaction. -Monitor hematologic,elect rolytes, renal and hepatic function. Assess for possible superinfection: itching fever, malaise, redness, diarhhea