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ii ACKNOWLEDGMENT

Life is a story that was written by us. No one could ever manipulate the script you have written nor the draft you have made. It is something that was thoroughly experienced by each of us. Values are beliefs shared by the members of a culture on what is good from bad and what is desirable and undesirable. It serves as guiding principle in a persons attitude. As a value- laden person it is very fitting to give heartfelt thanks and gratitude to those who helped in one way or another towards the completion of this thesis. Sr. Carolina S. Agravante, SPC, President of St. Paul University Iloilo, Dean of the College of Nursing, and Research I instructor, for the inspiration and enlightenment towards the love for research as well as her knowledge, approval, and support; Engr. Teresa Mallare, Research Adviser, for giving much time in patiently and tirelessly correcting the thesis despite her hectic schedule and for dedicatedly guiding with immense expertise, unwavering constant motivation, and firm belief that this study will be completed; Special mention given to Ms. Jimzie Lane Donguines, the ASC 2013, ACC 2013 for without their help and encouragement I will not be able to finish my study; Christine Epilepsia RN, MSN, Dr. Manuel Gayoles, Fr. Paul Solomia, members of the Ethics Committee, for their approval to the conduct of the study;

iii His research panelists, other members of the faculty, and staff of St. Paul University Iloilo, for their assistance, expertise, and valuable suggestions; Mr. and Mrs. Rex Baltazar, his beloved parents, Ms. Regene Mae Baltazar and Ms. Rexene Mae Baltazar, his sisters, relatives, and friends for the unconditional love, inspiration, understanding, encouragement and valuable moral, financial, and spiritual support given to him during him hardships which are deemed truly necessary for the completion of this study; and above all, The Almighty God, for His Divine intervention, invincible wisdom, and bountiful blessings for with Him, nothing is impossible to the researcher.

The Researcher

iv DEDICATION

This thesis is dedicated to God, my family, my closest friends, and the ASC 2013, whose unconditional love and support continue to inspire me in the pursuit of this study. Together, we continue to strive for holistic care.

v Baltazar, John Rex Jr. O. (2013). Effects of Gin on the Blood Glucose Levels of Mice. Unpublished undergraduate thesis (Bachelor of Science in Nursing, St. Paul University Iloilo, Iloilo City).

ABSTRACT This experimental study determined the effects of gin on the blood glucose levels of mice. Specifically, it aimed to determine (1) determine the blood glucose levels of mice before Alloxan induction (2) determine the blood glucose of mice after Alloxan induction (3) determine which treatment will significantly decrease the blood glucose of mice. In this study, the data gathered showed the positive effects of alcohol (gin) and Metformin hydrochloride to the blood glucose levels of Alloxan induced mice in the different Treatment groups. Trt 1(WAMA) labeled as With Alloxan monohydrate with Metformin hydrochloride with alcohol had significant difference with Trt 2 (WAA). Trt 2 (WAA) labeled as With Alloxan monohydrate without Metformin hydrochloride with alcohol has significant differences with all other treatments. Treatment 3 (WAM) labeled as With Alloxan monohydrate with Metformin hydrochloride without alcohol has significant difference to Trt 2 (WAA). Trt 4 (WA) labeled as With Alloxan monohydrate without Metformin hydrochloride without alcohol has significant difference with all other treatments. This has happened because of the constant high levels of blood glucose results that were gathered every time the mice are subjected to blood sampling. This means that alcohol is effective in lowering the blood glucose levels. Trt 1(WAMA) and 3 (WAM) have comparable results in lowering the blood glucose levels of mice. This study has shown that: generally, alcohol when given in combination

vi with Metformin of Diabetes mellitus produced greater decline in the blood glucose levels of mice than Metformin alone. Percentage change in the case of the Normoglycemic mice showed that the blood glucose levels of mice which belong to Trt 5 (MA) which were given Metfromin and alcohol had the greatest drop in the blood glucose levels which means that alcohol (gin) when given together in non-diabetic mice produce greater change in the blood glucose when compared to that of Trt 6 (M) which were given Metformin only. This suggests that alcohol and Metformin when given together produce greater blood glucose decrease regardless if the mice are diabetic or not.