Reaction Risk Assessment Form.

Reaction number: 1S (Part 1, Part 2 overleaf)

Write your reaction here including work-up and purification method (e.g. chromatography). Use the form below to risk assess ALL associated reaction and process conditions (e.g. heating, cooling, vacuum), particular hazards (e.g., exotherm, gas evolution, flooding, asphyxiation, burns - hot or cold, explosion), quench procedures, and waste disposal as well as the chemicals to be used, including your expected product, solvents, and known byproducts.

Chemical hazards and routes of exposure

Highly flammable, flammable
Route of exposure: 1 Inhalation; 2. Skin/eye contact; 3 Swallowing

Compound Dicyclopentadiene (1) Cyclopentadiene (2) Iron(II)chloride tetrahydrate (3) Diethylether (4) Potassium hydroxide (5) Dimethylsulfoxide (6) Ferrocene (7) Aqueous hydrogen chloride (8)

FW 132.20 66.10 198.81 74.12 56.11 78.13 186.03 n/a

d 0.986 0.786 n/a 0.706 n/a 1.10 n/a n/a

Quantity 60 mL 8.5 mL 10 g 100 mL 40 g 40 mL 9.36 g 80 mL

mmols n/a 164 50.3 n/a 713 n/a 50.3 n/a

equiv n/a 3.3 1 n/a exc. n/a 1 n/a

1,2,3 1,2,3 1,2,3 1,2,3 1,2,3 1,2,3 1,2,3 1,2,3 x x

x x

x x x x x x x x

Repeat experiment (this book only - please circle one) New experiment (Please circle one):

No

/ Yes (previous assessment on page:

Category:

Standard protocol followed? (Please give reference) As per laboratory manual Reaction conditions and associated processes (heat, cooling, pressure, vacuum etc) and hazards:
(Refer to general risk assessments on Departmental safety website)

Rotavap
Safety glasses: x Control Measures: (please tick boxes) Gloves (type): Scrubbing train (type): Lab coat: x Nitrile: x Fume hood: x Marigolds: Other: Safety screen: Other:

Are specific emergency procedures necessary for this process: Yes/No. If Yes, give details:

In case of spill contain in fume cupboard, close sash, notify demonstrator Reaction and/or reagent quench: n/a
(Give quench type and possible hazard)

Waste disposal: Chlorinated Waste

(circle as appropriate)

Hydrocarbon Waste

Silica Waste

Other (specify):

1, 2, 4, 6, 7 Co-worker signature: JOE BLOGGS Designated Supervisor Signature: L Patel Date: 01/01/12 Date: 01/01/12

Other (specify): Environment

x

Carcinogen, teratogen, mutagen

Very toxic / toxic

Harmful/irritant

Lachrymator

Pyrophoric

Explosive

Corrosive

Oxidising

Reaction Risk Assessment Form.

Reaction number: 1S (Part 2)

Write your reaction here including work-up and purification method (e.g. chromatography). Use the form below to risk assess ALL associated reaction and process conditions (e.g. heating, cooling, vacuum), particular hazards (e.g., exotherm, gas evolution, flooding, asphyxiation, burns - hot or cold, explosion), quench procedures, and waste disposal as well as the chemicals to be used, including your expected product, solvents, and known byproducts.

Chemical hazards and routes of exposure

Highly flammable, flammable
Route of exposure: 1 Inhalation; 2. Skin/eye contact; 3 Swallowing

Compound
Ferrocene (1) Dichloromethane (2) Toluene (3) Nitric acid (4) Acetic anhydride (5) Phosphoric acid (6) Acetyl ferrocene (7) Cyclohexane (8)

FW
186.03 84.93 92.14 n/a 102.09 n/a 228.07 n/a

d
n/a 1.325 0.865 n/a 1.08 1.685 n/a n/a

Quantity
3.0 g n/a n/a 5 mL 10 mL 2 mL 3.7 g n/a

mmols
16.1 n/a n/a n/a 90.7 n/a 16.1 n/a

equiv
1 n/a n/a n/a xs cat 1 n/a 1,2,3 1,2,3 1,2,3 1,2,3 1,2,3 1,2,3 1,2,3 1,2,3 x x x x x x x x x x x x x x x x

Repeat experiment (this book only - please circle one) New experiment (Please circle one):

No

/ Yes (previous assessment on page:

Category:

Standard protocol followed? (Please give reference) As per laboratory manual p.23 Reaction conditions and associated processes (heat, cooling, pressure, vacuum etc) and hazards:
(Refer to general risk assessments on Departmental safety website)

steam bath, vacuum desiccator Safety glasses: x

Control Measures: (please tick boxes) Gloves (type): Scrubbing train (type):

Lab coat: x Nitrile: x

Fume hood: x Marigolds: Other:

Safety screen: Other:

Are specific emergency procedures necessary for this process: Yes/No. If Yes, give details:

In case of spill contain in fume cupboard, close sash, notify demonstrator Reaction and/or reagent quench: Crushed ice
Waste disposal: Chlorinated Waste
(circle as appropriate)

Hydrocarbon Waste

Silica Waste

Other (specify):

Co-worker signature: Date: 01/01/12

1,3,8 JOE BLOGGS

Designated Supervisor Signature: L Patel Date: 01/01/12

Other (specify): Environment

Carcinogen, teratogen, mutagen

Very toxic / toxic

Harmful/irritant

Lachrymator

Pyrophoric

Explosive

Corrosive

Oxidising