A service of the U.S.

National Library of Medicine

My NCBI
and the National Institutes of Health
[Sign In] [Register]

All Databases PubMed Nucleotide Protein Genome Structure OMIM PMC Journals Books
Advanced Search
Search PubMed for Go
Clear
Limits Preview/Index History Clipboard Details

Display AbstractPlus Show 20 Sort By Send to

All: 1 Review: 0

1: In Vivo. 1988 May-Aug;2(3-4):247-52. Links

Antitumor activity of ascorbic acid in combination with antitumor agents against Lewis lung Related Articles
carcinoma.
Antitumor activity of calcium in combination with antitumor agents against Lewis
lung carcinoma. [I nVivo. 1989]
Nakano K, Fujimoto S, Tokita H.
[Effect of combination immunochemotherapy with an organogermanium
Shizuoka Sena Hospital, Japan. compound, Ge-132, and antitumor agents on C57BL/6[Gmice
an Tobearing
Kag akuLewis lung
Ry oho. 1986]
Antitumor activity of a C-raf antisense oligonucleotide in combination with
Antitumor activity of ascorbic acid in combination with antitumor agents (mitomycin C and 5-fluorouracil) was standard chemotherapeutic agents against various human tumors transplanted
[ClinCancer Res. 1997]
examined against subcutaneously implanted Lewis lung carcinoma-bearing C57BL/6 mice by feeding them an
ascorbic acid-deficient diet. The mice were divided into four groups: group 1 received intraperitoneally Antitumor activity of cryptophycins: effect of infusion time and combination
mitomycin C (2 mg/kg) and 5-fluorouracil (50 mg/kg) once a week for four weeks beginning from the day after studies. [Cancer Chemoth er Pha rmacol. 2000]
implantation of tumors, as well as ascorbic acid (1000 mg/kg) twice a week for the same four weeks; group 2 Enhanced suppression of tumor growth by combination of angiogenesis inhibitor
received only mitomycin C and 5-fluorouracil; group 3 received only ascorbic acid; group 4 received a vehicle O-(chloroacetyl-carbamoyl)fumagillol (TNP-470) and cytotoxic agents in mice.
[Cancer Res. 1994]
(physiological saline). Tumor growth of group 1 compared with the other three groups, and that of group 2
» See All...
compared with groups 3 and 4, was significantly inhibited by day 13 post implantation. Histological
examinations of tumor tissues at 10 days after implantation of tumors already showed degenerative changes
Patient Drug Information
which indicated these antitumor effects.

PMID: 2979840 [PubMed - indexed for MEDLINE] Ascorbic Acid (Cecon® Drops, Cenolate® , Cevi-Bid® , ...) Ascorbic acid is used
to prevent and treat scurvy, a disease caused by a lack of vitamin C in the body.

Fluorouracil (Adrucil® ) Your doctor has ordered the drug fluorouracil to help treat
your illness. The drug is given by injection into a vein.

Mitomycin (Mutamycin® ) Your doctor has ordered the drug mitomycin to help
treat your illness. The drug is given by injection into a vein.

Source: AHFS Consumer Medication Information

Recent Activity
Turn Off Clear

Antitumor activity of ascorbic acid in combination with antitumor agents

against Lewis lun...

Effect of ascorbic acid on the intragastric environment in patients at

increased risk of d...

Ultrastructure and cell surface studies of cancer cells following vitamin C

administration...

Potential protective effect of vitamin C on carcinogenesis caused by

nitrosamine in drinki...

Characterization of a new malignant human T-cell line (PFI-285) sensitive to

ascorbic acid...

Display AbstractPlus Show 20 Sort By Send to

Write to the Help Desk
NCBI | NLM | NIH
Department of Health & Human Services
Privacy Statement | Freedom of Information Act | Disclaimer