NURS 1566 Clinical Form 3: Clinical Medications Worksheets

Generic Name Trade Name Classification Dose Route Time/frequency

Ziprasidone Geodon Antipsychotic 80mg PO Bid
Peak Onset Duration Normal dosage range
1-3 days Within Unknown 40mg twice on first day, then 60 or 80mg twice daily on
hours second day, then 40-80mg twice daily.
Why is your patient getting this medication For IV meds, compatibility with IV drips and/or
Psychosis solutions
N/A
Mechanism of action and indications Nursing Implications (what to focus on)
The mechanism of action of Ziprasidone, as with Contraindications/warnings/interactions
other drugs used to treat schizophrenia, is unknown. Use cautiously during cases of diarrhea, hepatic
Ziprasidone exhibited high in vitro binding affinity impairment, dehydration.
for the dopamine D2 and D3, the serotonin 5HT2A, Common side effects
5HT2C, 5HT1A, 5HT1D and alpha 1-adrenergic NEUROLEPTIC MALIGNANT SYNDROME, dizziness,
receptors, and moderate affinity for the histamine drowsiness, restlessness, PROLONGED QT INTERVAL,
H1 receptor. However, it has been proposed that the constipation, diarrhea, nausea
drug's therapeutic activity in schizophrenia is
mediated through a combination of dopamine Type 2
(D2) and serotonin Type 2 (5HT2) receptor
antagonism.
Interactions with other patient drugs, OTC or Lab value alterations caused by medicine
herbal medicines (ask patient specifically) Monitor serum potassium and magnesium prior to and
BuSpar: CNS and/or respiratory-depressant effects periodically during therapy.
may be additively or synergistically increased in Be sure to teach the patient the following about this
patients taking multiple drugs that cause these medication
effects. Instruct patient to take medication as directed and not to
Seroquel: There is some concern that quetiapine may discontinue medication without discussing it with provider.
have additive adverse cardiovascular effects in Inform patient of risk of EPS and to report them
combination with other drugs that are known to immediately if noticed. Advise patient to change position
prolong the QT interval of the electrocardiogram. slowly to minimize orthostatic hypotension. May cause
Data are conflicting. seizures and drowsiness, so don’t drive or operate heavy
machinery until effects are known. Avoid alcohol, other
CNS depressants, OTC medications and herbal products
unless approved by provider. Notify provider if pregnancy
is planned or suspected. Inform about need for follow-up
psychotherapy, eye exams, and lab tests.
Nursing Process- Assessment Assessment Evaluation
(Pre-administration assessment) Why would you hold or not give this Check after giving
Monitor mental status prior to and during med? Diminished psychotic
therapy. Monitor orthostatic BP prior to Cardiac dysrythmias behaviors.
and frequently during initial dose titration.
Assess for rash. Ensure patient is not
hording medication. Assess for onset of
EPS every 2 months. Monitor for
constipation, seizures.